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Protein

Clustered mitochondria protein homolog

Gene

cluh

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Clustered mitochondria protein homologUniRule annotation
Gene namesi
Name:cluhUniRule annotation
ORF Names:zgc:152873
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Unplaced

Organism-specific databases

ZFINiZDB-GENE-061103-457 cluha

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003663741 – 1400Clustered mitochondria protein homologAdd BLAST1400

Proteomic databases

PaxDbiA0JMD0
PeptideAtlasiA0JMD0
PRIDEiA0JMD0

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000047470

Structurei

3D structure databases

ProteinModelPortaliA0JMD0
SMRiA0JMD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini380 – 622CluPROSITE-ProRule annotationAdd BLAST243
Repeati1088 – 1121TPR 1Add BLAST34
Repeati1130 – 1163TPR 2Add BLAST34
Repeati1172 – 1205TPR 3Add BLAST34
Repeati1214 – 1247TPR 4Add BLAST34

Sequence similaritiesi

Belongs to the CLU family.UniRule annotation

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiKOG1839 Eukaryota
ENOG410XQUQ LUCA
HOGENOMiHOG000113156
HOVERGENiHBG108020
InParanoidiA0JMD0
KOiK03255
PhylomeDBiA0JMD0

Family and domain databases

CDDicd15466 CLU-central, 1 hit
Gene3Di1.25.40.10, 1 hit
HAMAPiMF_03013 CLU, 1 hit
InterProiView protein in InterPro
IPR027523 CLU
IPR033646 CLU-central
IPR025697 CLU_dom
IPR028275 CLU_N
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF13236 CLU, 1 hit
PF15044 CLU_N, 1 hit
PF12807 eIF3_p135, 1 hit
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS51823 CLU, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A0JMD0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSKTDDIPA SVPNCSPADF ARDGETANSK GTTSKKEASC ACGHGVETAV
60 70 80 90 100
MNGDAGHDQA EEADSKQDGS GDADQAEDAN EQEVIVIQDT GFTVKIQAPG
110 120 130 140 150
TEPFDLQVSP QEMVQEIHQV LMDREDTCHR TCFSLQLDGN VLDNFAELKS
160 170 180 190 200
IEGLQEGSLL KVVEEPYTVR EARIHVRHIR DLLKSLDPSD AYNGVDCNSL
210 220 230 240 250
SFLSVFSEGD LGDTGKRKKK GSELEQIDCT PPEHILPGSK ERPLVPLQPQ
260 270 280 290 300
NKDWKPMQCL KVLTMSSWNP PPGNRKMHGD LMYLYIVTVE DRHVSITAST
310 320 330 340 350
RGFYLNQSTT YNFSPKPANP SFLSHSLVEL LSQISAAFKK NFTTLQKKRV
360 370 380 390 400
QRHPFERIAT PFQVYSWTAP QIDHAMDCVR AEDAYTSRLG YEEHIPGQTR
410 420 430 440 450
DWNEELQTTR ELSRKNLPER LLRERAIFKV HSDFAAAATR GAMAVIDGNV
460 470 480 490 500
MAINPGEETR MQMFIWNNIF FSLGFDVRDH YRELGGDSAA HAAPTNDLNG
510 520 530 540 550
VRAYSAVDVE GLYTLGTVVV DYRGYRVTAQ SIIPGILERE QEQSVIYGSI
560 570 580 590 600
DFGKTVVSHP KYLELLEKTS RPLKVQRHAV LNEKDSAVEL CSSVECKGII
610 620 630 640 650
GNDGRHYILD LLRTFPPDLN FLPVEGEELT PESQKLGFPR QHRHRLACLR
660 670 680 690 700
QELIEAFVEH RYLLFMKMAA LQLMQQKANK DKTAALQDSN AAGAGSENKP
710 720 730 740 750
LALESCDGTP DSPTSSESTL TPEDSEATTV SENSSAENQE AMTEVPVASI
760 770 780 790 800
NGTHEPLAAE RQNGGCDGPL EGKEADENIP GLAQAKELAE SLAAEDGSGI
810 820 830 840 850
DPKSREVVLN ACKAVGSISN TSFDIRFNPD IFSPGVRFPD DSNDDIKKQK
860 870 880 890 900
QLLKDAAAFL VSCQIPSLVK DCLDHSSLPM DGATLTEALH QRGINVRYLG
910 920 930 940 950
TVLEFMDNMP AKAQLEHIYR IGISELITRC AKHIFKTYLQ GVDLSALSAA
960 970 980 990 1000
VSYFLNCLLS SFPDAVAHLP ADELVSRKKS RKRRNRVPGG GDNTAWASLT
1010 1020 1030 1040 1050
PSELWKNITS EAHGYYNFSL QCESVDQAVE KYGLQKITLL REISIKTGIQ
1060 1070 1080 1090 1100
ILIKEYNFDS RHKPAFTEED ILNIFPVVKH VNPKASDAFH FFQSGQAKVQ
1110 1120 1130 1140 1150
QGFLKEGCEL INEALNLFNN VYGAMHVEIC ACLRLLARLN YIMGDHPEAL
1160 1170 1180 1190 1200
SNQQKAVLMS ERVLGIEHPN TIQEYMHLAL YCFANGQLST ALKLLYRARY
1210 1220 1230 1240 1250
LMLVVCGEDH PEMALLDSNI GLVLHGVMEY DLSLRFLENA LAINTKYHGP
1260 1270 1280 1290 1300
RSLKVALSHH LVARVYESKA EFRSALQHEK EGYTIYKNQV GEAHEKTKES
1310 1320 1330 1340 1350
SEYLKYLTQQ AVALQRTMNE IYKNGSNASI MPLKFTAPSM ASVLEQLNII
1360 1370 1380 1390 1400
NGIIFIPLSQ KDLENLKAEV QRRQLMQDSG KIQEQQGSHL ELDDKLPVDD
Length:1,400
Mass (Da):155,810
Last modified:December 12, 2006 - v1
Checksum:i515A6C85819C1ED9
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1QSU2F1QSU2_DANRE
Clustered mitochondria protein homo...
cluha cluh
1,400Annotation score:
R4GER3R4GER3_DANRE
Clustered mitochondria (cluA/CLU1) ...
cluha cluh
124Annotation score:
R4GE78R4GE78_DANRE
Clustered mitochondria (cluA/CLU1) ...
cluha cluh
171Annotation score:
R4GE19R4GE19_DANRE
Clustered mitochondria (cluA/CLU1) ...
cluha cluh
104Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti1304L → S in AAH90714 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090714 mRNA Translation: AAH90714.1
BC125829 mRNA Translation: AAI25830.1
RefSeqiNP_001071028.1, NM_001077560.1
UniGeneiDr.39110

Genome annotation databases

GeneIDi562666
KEGGidre:562666

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC090714 mRNA Translation: AAH90714.1
BC125829 mRNA Translation: AAI25830.1
RefSeqiNP_001071028.1, NM_001077560.1
UniGeneiDr.39110

3D structure databases

ProteinModelPortaliA0JMD0
SMRiA0JMD0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000047470

Proteomic databases

PaxDbiA0JMD0
PeptideAtlasiA0JMD0
PRIDEiA0JMD0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi562666
KEGGidre:562666

Organism-specific databases

CTDi562666
ZFINiZDB-GENE-061103-457 cluha

Phylogenomic databases

eggNOGiKOG1839 Eukaryota
ENOG410XQUQ LUCA
HOGENOMiHOG000113156
HOVERGENiHBG108020
InParanoidiA0JMD0
KOiK03255
PhylomeDBiA0JMD0

Miscellaneous databases

PROiPR:A0JMD0

Family and domain databases

CDDicd15466 CLU-central, 1 hit
Gene3Di1.25.40.10, 1 hit
HAMAPiMF_03013 CLU, 1 hit
InterProiView protein in InterPro
IPR027523 CLU
IPR033646 CLU-central
IPR025697 CLU_dom
IPR028275 CLU_N
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF13236 CLU, 1 hit
PF15044 CLU_N, 1 hit
PF12807 eIF3_p135, 1 hit
SUPFAMiSSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS51823 CLU, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCLU_DANRE
AccessioniPrimary (citable) accession number: A0JMD0
Secondary accession number(s): Q5CZT5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: December 12, 2006
Last modified: February 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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