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Entry version 65 (08 May 2019)
Sequence version 1 (28 Nov 2006)
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Protein
Submitted name:

Uncharacterized protein

Gene

GSPATT00001565001

Organism
Paramecium tetraurelia
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.3.2.4 the ryanodine-inositol 1,4,5-triphosphate receptor ca(2+) channel (rir-cac) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:GSPATT00001565001Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiParamecium tetraureliaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5888 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataCiliophoraIntramacronucleataOligohymenophoreaPeniculidaParameciidaeParamecium
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000600 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Partially assembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2400 – 2417HelicalSequence analysisAdd BLAST18
Transmembranei2601 – 2621HelicalSequence analysisAdd BLAST21
Transmembranei2659 – 2680HelicalSequence analysisAdd BLAST22
Transmembranei2687 – 2708HelicalSequence analysisAdd BLAST22
Transmembranei2728 – 2753HelicalSequence analysisAdd BLAST26
Transmembranei2774 – 2794HelicalSequence analysisAdd BLAST21
Transmembranei2877 – 2898HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5888.CAK75361

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini382 – 430MIRInterPro annotationAdd BLAST49
Domaini438 – 502MIRInterPro annotationAdd BLAST65

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili776 – 822Sequence analysisAdd BLAST47
Coiled coili1171 – 1209Sequence analysisAdd BLAST39
Coiled coili2481 – 2515Sequence analysisAdd BLAST35
Coiled coili3002 – 3032Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2243 Eukaryota
KOG3533 Eukaryota
ENOG410XR97 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A0CX44

KEGG Orthology (KO)

More...
KOi
K04960

Identification of Orthologs from Complete Genome Data

More...
OMAi
LECNINS

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014821 Ins145_P3_rcpt
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR013662 RIH_assoc-dom
IPR035910 RyR/IP3R_RIH_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08709 Ins145_P3_rec, 1 hit
PF02815 MIR, 1 hit
PF08454 RIH_assoc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF100909 SSF100909, 1 hit
SSF82109 SSF82109, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50919 MIR, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0CX44-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSQPITYSSL ISLSLAKFPQ VYMYTDGFMS NDFELISFNS VHGNLFHDFQ
60 70 80 90 100
NTVFRIIPVL NFKWTQKLLK EIVQEDFQKL SEIQVVKQRK GQIQSLRTNL
110 120 130 140 150
DGEVTSNISL TSKLTGVPLI FGSSTFMLVH VTSLKFLTLN DENPEDLHFQ
160 170 180 190 200
LKDFPEEGSI MKFTPCLNFQ KLRTNIVYNK DAVILSSTKV VCNRPPSLYT
210 220 230 240 250
FYKGQEYKYK ESKDKQLKKQ FQQEVKRSKI IGSIEYQTRW RVEGYHCASN
260 270 280 290 300
NEKQSEFDDY LHVGDVIALY LSELKLHVNA LKPYDPFKKI LQILKIENLT
310 320 330 340 350
SAEPQTKQKD QLLKLTKTQQ HLDKEFNLNQ SDAKILKKIL IEDVVVTFQN
360 370 380 390 400
FNYFNSTESQ KKLLDLPNSC FWKIESADQM SGGRVDWNKI YRLRHYQTGR
410 420 430 440 450
YLQITKNGNL VDMELISEPN QNALFKFSQI QNSEDSEVTY IKRDSFYYLL
460 470 480 490 500
HIETGQYLGI SDEVNEVNPK IEQLSKEAEV EVKQAYLSVV QNHYTTFRVK
510 520 530 540 550
KIDFSDMWET YMLQYSLPFF LEAIDYIQRL HQKHIVNSTI AYNDEDIKSK
560 570 580 590 600
LHFYQIFLKL DRMLDMYCEF VNNKLISNIS AKQEYSYIVT NRQNVVREQN
610 620 630 640 650
IFILLVWMLF RCFPSRQIIE KYPQKFEAMK IDFMDEKDFI FRVQSFLQSN
660 670 680 690 700
TLKHHPRMLV KLEDGHNKRQ IYLSYKVYMT IKDFCKDNKS NQRTLMKLLN
710 720 730 740 750
IFYNHIGLGD QIVDTLANSI SKTKSILQQL PKTMISMPQK PNQDEHQNHS
760 770 780 790 800
TSQDKSQVQG DQIKVMDQSN LSMTAHNKSK ERVSQKEIEL QREKEKEQQK
810 820 830 840 850
LKEQQEKQKE KEKQQKNESN SLQAIILKLL EFPPFSKPDI IYLLATVCQS
860 870 880 890 900
LESPVFVNQN LIYRAFFENK LIYNHAFMKL TYKFGDLLLT CLDKNDQPVT
910 920 930 940 950
IKFLDFFDDP RLESGANYQR QFEYIKNELN LIANLCLSRN TLACKTFQQT
960 970 980 990 1000
FLFNKTLPFV ENSNLKEEIR AVFLKLIRVL YIDQEPYQTQ KRPELVREII
1010 1020 1030 1040 1050
YDKSILTTKL IKQDGGILSM LKMNANNYVS FEEIQKRQLE PLISKDTILY
1060 1070 1080 1090 1100
QTMRVKKLKQ QQINWERIQK EQAIDESEVE ESEEVKKFLQ SLIKILIQHI
1110 1120 1130 1140 1150
QESAQKLTSL KQGRLIYNIL TLEVIQIVKL IFQFGFFNYE YIKPPNQHTK
1160 1170 1180 1190 1200
KSQAIMREIE KQIKNSEIEQ IIQLLAQLLE YDEQYNQALE NANVQRKYIE
1210 1220 1230 1240 1250
NKLKRDEKKK KNAFDDLANL GNINLDMMNL LDGAEKQKKE RKIIHQDIEM
1260 1270 1280 1290 1300
EIINDPLFRK VKQLKKILDK CSNKTFSIKQ EDQFTQYEVQ IKMEICEIFI
1310 1320 1330 1340 1350
LMLGMRQDFL IDNAIDFFKQ QFVPYQVSMI DENHNYTDLL PELGIEVGED
1360 1370 1380 1390 1400
VDSIQTMKEY CEKFQTVRNF DIILDRPFYE TLILSLFFST NAKLSNKIVE
1410 1420 1430 1440 1450
LIEKYSSQRY DLVQNLTELQ VVVSMETIAF YKKWSRLLNK LKRNIPNCQA
1460 1470 1480 1490 1500
WLQLDTPQKL NGRNETNFQK NLKLVKKIID VFQENAGDNQ RMKIKQRIFK
1510 1520 1530 1540 1550
HVGGFDSMLE LMLSCMIMII NNRQVFTFKE APTSFSQYQQ HLAKLILQLL
1560 1570 1580 1590 1600
ECILQIMVFF GKNSIENQEL VFHKVVPHLT KYRRNNFNQS QFITDLLNDN
1610 1620 1630 1640 1650
PKLTQHINRD REIEYFFKLI KKHGRYTEFI DFFLIILKNA ESNKTGQSNV
1660 1670 1680 1690 1700
LSMHIINFVL DKKYFEFCNP FVPQPKLKGK SLFYQHKPQS SYLGKFIIML
1710 1720 1730 1740 1750
AQCLKNYIGV SLTYRAQQTF KLNLLLESLV QISSEERETA FEQFNQLEVK
1760 1770 1780 1790 1800
TCIFEIIMVV LERAEKKNLE IMSCSEKIQE FLVLESQFLN SRQQFSNAQL
1810 1820 1830 1840 1850
IYLFQKQSPF LLQYFKAFYK DAGAKLFQNA EQSKIERKKI QEYGKAFLNA
1860 1870 1880 1890 1900
LNHMSQKTIM DDVPKISMVE DLCRALKIDI PKSFRRPVNS DDEIDDDVEE
1910 1920 1930 1940 1950
QEDETDDKAK QISMDVSNEN THQKGSFTTG PPLVNENTAR AFLQKFKSLK
1960 1970 1980 1990 2000
AKQLQTDKKD NEDSESKQIN YYWQLFVSLL SDNEQVHEAI KEEKQIFANS
2010 2020 2030 2040 2050
VWNISQMFQS DIKSDQKDLV LNQEDVVKNL LNYIQYWQVN AADKKSVLFI
2060 2070 2080 2090 2100
FKALKQILKN PFRSDDLDEL RERQEILNKL NATKILMQLL WSEDENDLQY
2110 2120 2130 2140 2150
LTTLLSLFCM MLKKGNLVVQ TTILEYSKSN QECEKLYFKL NLIIANYINS
2160 2170 2180 2190 2200
NPAELKQQGK LQTKLICKTL QFMQLLCEGH NLQLQEYLHQ QTNSKTSYDL
2210 2220 2230 2240 2250
VLQIVKLQQC IKIDNKNYGI VTQCFDTITE VIQGPCKTNQ IALSNSKFME
2260 2270 2280 2290 2300
YVVDVLSENE KLFETQEIQK KQEAKLLGVI FKQVQTQKKE FKSFNQMGQT
2310 2320 2330 2340 2350
KEQQGIKRNK IMDPTKPYNL TLHLAKLARL KLKALISLVS LVECCDLQDN
2360 2370 2380 2390 2400
LILRIIRAIP IRVLTNNMSR QYFKDEYKEE LFGRAEQLIV LTEEEEKYEL
2410 2420 2430 2440 2450
VVEIGFYIYI LMQIFVASKK GKDILQEDIE MREILNEFDV DRADEQSTGL
2460 2470 2480 2490 2500
FSGISKLGGQ MLQVGLGGLQ KFKQGIEEVG KTDEDRRKEK EAQELEEKKK
2510 2520 2530 2540 2550
NKELLKNSIR FFKKNSCSIE IVREEKVYQV FFPKLPYCHQ LPKDLKTEFH
2560 2570 2580 2590 2600
DEVNRSSAKT KLNYLMTKSE SIIKTMKHEE YLRILFNINP IFGAIASQGK
2610 2620 2630 2640 2650
LWELCLFLTT IAINLIILFS YSQFLVPDQY LDNDSRIQYY RLYEPRLLWY
2660 2670 2680 2690 2700
DQLSITKQII LILGILDLAF SSLIVFFFAL KRAPLKVYHI WVGFFSTQGF
2710 2720 2730 2740 2750
FKIIIRLIKN SLVSIFVLLQ DFEILYYSAY ILAGIVGLAA HPFFFCVHLM
2760 2770 2780 2790 2800
DFLKLDQLKT VVQAIWKPKV ELGLALMLLI IIEYYFNILA WIVFYNQYPA
2810 2820 2830 2840 2850
SGESGQEYCN EFWRCLITTF DWTFKFTGSI GAHLQDPATL EELQKQAVLQ
2860 2870 2880 2890 2900
GDEDASYDYV NADQTAIYYE RFFFDNLFNI MLVFILLNMI QGIIIDTFSS
2910 2920 2930 2940 2950
LREDLAEKNK DMEFKCFVCG FDMETLDKSS DSDKGFAFHI KYEHHMWNYV
2960 2970 2980 2990 3000
FYFAYLQFKD PTEYDGNETF VSNKMENLDL GWLPIKKAKC ITDENQEDKK
3010 3020 3030
KLEQLDLLNK KADKIEEDLK KQTEKVEKIY KSLLPE
Length:3,036
Mass (Da):357,633
Last modified:November 28, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6EFE3D75AB76D592
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CT868207 Genomic DNA Translation: CAK75361.1

NCBI Reference Sequences

More...
RefSeqi
XP_001442758.1, XM_001442721.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAK75361; CAK75361; GSPATT00001565001

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5028543

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ptm:GSPATT00001565001

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT868207 Genomic DNA Translation: CAK75361.1
RefSeqiXP_001442758.1, XM_001442721.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5888.CAK75361

Protein family/group databases

TCDBi1.A.3.2.4 the ryanodine-inositol 1,4,5-triphosphate receptor ca(2+) channel (rir-cac) family

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAK75361; CAK75361; GSPATT00001565001
GeneIDi5028543
KEGGiptm:GSPATT00001565001

Phylogenomic databases

eggNOGiKOG2243 Eukaryota
KOG3533 Eukaryota
ENOG410XR97 LUCA
InParanoidiA0CX44
KOiK04960
OMAiLECNINS

Family and domain databases

InterProiView protein in InterPro
IPR014821 Ins145_P3_rcpt
IPR036300 MIR_dom_sf
IPR016093 MIR_motif
IPR013662 RIH_assoc-dom
IPR035910 RyR/IP3R_RIH_dom_sf
PfamiView protein in Pfam
PF08709 Ins145_P3_rec, 1 hit
PF02815 MIR, 1 hit
PF08454 RIH_assoc, 1 hit
SUPFAMiSSF100909 SSF100909, 1 hit
SSF82109 SSF82109, 1 hit
PROSITEiView protein in PROSITE
PS50919 MIR, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0CX44_PARTE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0CX44
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 28, 2006
Last sequence update: November 28, 2006
Last modified: May 8, 2019
This is version 65 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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