Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - A0A7I2YQ65 (A0A7I2YQ65_HUMAN)

Entry version 4 (25 May 2022)
Sequence version 1 (07 Apr 2021)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

Gene

GBF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GBF1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:4181, GBF1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000107862

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...PeptideAtlasi		A0A7I2YQ65

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A0A7I2YQ65

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini594 – 784SEC7InterPro annotationAdd BLAST191

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni215 – 266DisorderedSequence analysisAdd BLAST52
Regioni281 – 373DisorderedSequence analysisAdd BLAST93
Regioni521 – 567DisorderedSequence analysisAdd BLAST47
Regioni1186 – 1237DisorderedSequence analysisAdd BLAST52
Regioni1252 – 1272DisorderedSequence analysisAdd BLAST21
Regioni1332 – 1385DisorderedSequence analysisAdd BLAST54
Regioni1623 – 1706DisorderedSequence analysisAdd BLAST84

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi246 – 265Polar residuesSequence analysisAdd BLAST20
Compositional biasi281 – 326Polar residuesSequence analysisAdd BLAST46
Compositional biasi1202 – 1220Polar residuesSequence analysisAdd BLAST19
Compositional biasi1221 – 1237Basic and acidic residuesSequence analysisAdd BLAST17
Compositional biasi1672 – 1691Polar residuesSequence analysisAdd BLAST20
Compositional biasi1692 – 1706Pro residuesSequence analysisAdd BLAST15

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156925

Family and domain databases

Conserved Domains Database

More...CDDi		cd00171, Sec7, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1000.11, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR023394, Sec7_C_sf
IPR000904, Sec7_dom
IPR035999, Sec7_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01369, Sec7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00222, Sec7, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48425, SSF48425, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50190, SEC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 84 potential isoforms that are computationally mapped.Show allAlign All

A0A7I2YQ65-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVDKNIYIIQ GEINIVVGAI KRNARWSTHT PLDEERDPLL HSFGHLKEVL 
        60         70         80         90        100
NSITELSEIE PNVFLRPFLE VIRSEDTTGP ITGLALTSVN KFLSYALIDP 
       110        120        130        140        150
THEGTAEGME NMADAVTHAR FVGTDPASDE VVLMKILQVL RTLLLTPVGA 
       160        170        180        190        200
HLTNESVCEI MQSCFRICFE MRLSELLRKS AEHTLVDMVQ LLFTRLPQFK 
       210        220        230        240        250
EEPKNYVGTN MKKLKMRAGG MSDSSKWKKQ KRSPRPPRHM TKVTPGSELP 
       260        270        280        290        300
TPNGTTLSSN LTGGMPFIDV PTPISSASSE AASAVVSPST DSGLEFSSQT 
       310        320        330        340        350
TSKEDLTDLE QPGSPGYSTA TEPGSSELGV PEQPDLQEGT HVEKSQSASV 
       360        370        380        390        400
ESIPEVLEEC TSPADHSDSA SVHDMDYVNP RGVRFTQSSQ KEGTALVPYG 
       410        420        430        440        450
LPCIRELFRF LISLTNPHDR HNSEVMIHMG LHLLTVALES APVAQCQTLL 
       460        470        480        490        500
GLIKDEMCRH LFQNAFPVSG QLYTTHLLSL DALLTVIDST EAHCQAKVLN 
       510        520        530        540        550
SLTQQEKKET ARPSCEIVDG TREASNTERT ASDGKAVGMA SDIPGLHLPG 
       560        570        580        590        600
GGRLPPEHGK SGCSDLEEAV DSGADKKFAR KPPRFSCLLP DPRELIEIKN 
       610        620        630        640        650
KKKLLITGTE QFNQKPKKGI QFLQEKGLLT IPMDNTEVAQ WLRENPRLDK 
       660        670        680        690        700
KMIGEFVSDR KNIDLLESFV STFSFQGLRL DEALRLYLEA FRLPGEAPVI 
       710        720        730        740        750
QRLLEAFTER WMNCNGSPFA NSDACFSLAY AVIMLNTDQH NHNVRKQNAP 
       760        770        780        790        800
MTLEEFRKNL KGVNGGKDFE QDILEDMYHA IKNEEIVMPE EQTGLVRENY 
       810        820        830        840        850
VWNVLLHRGA TPEGIFLRVP TASYDLDLFT MTWGPTIAAL SYVFDKSLEE 
       860        870        880        890        900
TIIQKAISGF RKCAMISAHY GLSDVFDNLI ISLCKFTALS SESIENLPSV 
       910        920        930        940        950
FGSNPKAHIA AKTVFHLAHR HGDILREGWK NIMEAMLQLF RAQLLPKAMI 
       960        970        980        990       1000
EVEDFVDPNG KISLQREETP SNRGESTVLS FVSWLTLSGP EQSSVRGPST 
      1010       1020       1030       1040       1050
ENQEAKRVAL ECIKQCDPEK MITESKFLQL ESLQELMKAL VSVTPDEETY 
      1060       1070       1080       1090       1100
DEEDAAFCLE MLLRIVLENR DRVGCVWQTV RDHLYHLCVQ AQDFCFLVER 
      1110       1120       1130       1140       1150
AVVGLLRLAI RLLRREEISA QVLLSLRILL LMKPSVLSRV SHQVAYGLHE 
      1160       1170       1180       1190       1200
LLKTNAANIH SGDDWATLFT LLECIGSGVK PPAALQATAR ADAPDAGAQS 
      1210       1220       1230       1240       1250
DSELPSYHQN DVSLDRGYTS DSEVYTDHGR PGKIHRSATD ADVVNSGWLV 
      1260       1270       1280       1290       1300
VGKDDVDNSK PGPSRPGPSP LINQYSLTVG LDLGPHDTKS LLKCVESLSF 
      1310       1320       1330       1340       1350
IVRDAAHITP DNFELCVKTL RIFVEASLNG GCKSQEKRGK SHKYDSKGNR 
      1360       1370       1380       1390       1400
FKKKSKEGSM LRRPRTSSQH ASRGGQSDDD EDEGVPASYH TVSLQLLDLM 
      1410       1420       1430       1440       1450
HTLHTRAASI YSSWAEEQRH LETGGQKIEA DSRTLWAHCW CPLLQGIACL 
      1460       1470       1480       1490       1500
CCDARRQVRM QALTYLQRAL LVHDLQKLDA LEWESCFNKV LFPLLTKLLE 
      1510       1520       1530       1540       1550
NISPADVGGM EETRMRASTL LSKVFLQHLS PLLSLSTFAA LWLTILDFMD 
      1560       1570       1580       1590       1600
KYMHAGSSDL LSEAIPESLK NMLLVMDTAE IFHSADARGG GPSALWEITW 
      1610       1620       1630       1640       1650
ERIDCFLPHL RDELFKQTVI QDPMPMEPQG QKPLASAHLT SAAGDTRTPG 
      1660       1670       1680       1690       1700
HPPPPEIPSE LGACDFEKPE SPRAASSSSP GSPVASSPSR LSPTPDGPPP 
      1710       1720       1730       1740       1750
LAQPPLILQP LASPLQVGVP PMTLPIILNP ALIEATSPVP LLATPRPTDP 

IPTSEVN
Length:1,757
Mass (Da):194,172
Last modified:April 7, 2021 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDA36EFBF9EF70BD8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 84 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q92538GBF1_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1 KIAA0248
1,859Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A669KBG8A0A669KBG8_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,892Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A669KB10A0A669KB10_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,884Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V529A0A7I2V529_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,682Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7P0RGV0A0A7P0RGV0_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,860Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V2L4A0A7I2V2L4_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,489Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V3Y5A0A7I2V3Y5_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,493Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V452A0A7I2V452_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,843Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V4K2A0A7I2V4K2_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,600Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V514A0A7I2V514_HUMAN
Golgi-specific brefeldin A-resistan...
GBF1
1,761Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL121928 Genomic DNA No translation available.
AL160011 Genomic DNA No translation available.
AL356420 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000677618.1; ENSP00000502877.1; ENSG00000107862.7

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121928 Genomic DNA No translation available.
AL160011 Genomic DNA No translation available.
AL356420 Genomic DNA No translation available.

3D structure databases

SMRiA0A7I2YQ65
ModBaseiSearch...

Proteomic databases

PeptideAtlasiA0A7I2YQ65

Genome annotation databases

EnsembliENST00000677618.1; ENSP00000502877.1; ENSG00000107862.7

Organism-specific databases

HGNCiHGNC:4181, GBF1
OpenTargetsiENSG00000107862

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00940000156925

Family and domain databases

CDDicd00171, Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
InterProiView protein in InterPro
IPR023394, Sec7_C_sf
IPR000904, Sec7_dom
IPR035999, Sec7_dom_sf
PfamiView protein in Pfam
PF01369, Sec7, 1 hit
SMARTiView protein in SMART
SM00222, Sec7, 1 hit
SUPFAMiSSF48425, SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50190, SEC7, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A7I2YQ65_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A7I2YQ65
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 7, 2021
Last sequence update: April 7, 2021
Last modified: May 25, 2022
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again