The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - A0A7I2V3G4 (A0A7I2V3G4_HUMAN)
Protein
Submitted name:
Sec1 family domain-containing protein 1
Gene
SCFD1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- protein transport Source: UniProtKB-KW
- vesicle-mediated transport Source: InterPro
Keywordsi
Biological process | Protein transportARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Submitted name: Sec1 family domain-containing protein 1 |
Gene namesi | Name:SCFD1 |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:20726, SCFD1 |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 297 – 317 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the STXBP/unc-18/SEC1 family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00550000074845 |
Family and domain databases
Gene3Di | 3.40.50.1910, 1 hit 3.90.830.10, 1 hit |
InterProi | View protein in InterPro IPR043127, Sec-1-like_dom3a IPR001619, Sec1-like IPR027482, Sec1-like_dom2 IPR036045, Sec1-like_sf |
PANTHERi | PTHR11679, PTHR11679, 2 hits |
Pfami | View protein in Pfam PF00995, Sec1, 2 hits |
PIRSFi | PIRSF005715, VPS45_Sec1, 2 hits |
SUPFAMi | SSF56815, SSF56815, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 37 potential isoforms that are computationally mapped.Show allAlign All
A0A7I2V3G4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAAAAATAA AAASIRERQT VALKRMLNFN VPHIKNSTGE PVWKVLIYDR
60 70 80 90 100
FGQDIISPLL SVKELRDMGI TLHLLLHSDR DPIPDVPAVY FVMPTEENID
110 120 130 140 150
RMCQVFDQYL NFITLEDDMF VLCNQNKELV SYRAINRPDI TDTEMETVMD
160 170 180 190 200
TIVDSLFCFF VTLGAVPIIR CSRGTAAEMV AVKLDKKLRE NLRDARNSLF
210 220 230 240 250
TGDTLGAGQF SFQRPLLVLV DRNIDLATPL HHTWTYQALV HDVLDFHLNR
260 270 280 290 300
VNLEESSGVE NSPAGARPKR KNKKSYDLTP VDKFWQKHKG SPFPEVAESV
310 320 330 340 350
QQELESYRAQ EDEVKRLKSI MGLEGEDEGA ISMLSDNTAK LTSAVSSLPE
360 370 380 390 400
LLEKKRLIDL HTNVATAVLE HIKARKLDVY FEYEEKIMSK TTLDKSLLDI
410 420 430 440 450
ISDPDAGTPE DKMRLFLIYY ISTQQAPSEA DLEQYKKALT DAGCNLNPLQ
460 470 480 490 500
YIKQWKAFTK MASAPASYGS TTTKPMGLLS RVMNTGSQFV MEGVKNLVLK
510 520 530 540 550
QQNLPVTRIL DNLMEMKSNP ETDDYRYFDP KMLRGNDSSV PRNKNPFQEA
560 570 580 590 600
IVFVVGGGNY IEYQNLVDYI KGKQGKHILY GCSELFNATQ FIKQLSQLGQ
K
Computationally mapped potential isoform sequencesi
There are 37 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8WVM8 | SCFD1_HUMAN | Sec1 family domain-containing prote... | SCFD1 C14orf163, KIAA0917, STXBP1L2, FKSG23 | 642 | Annotation score: | ||
A0A7I2V448 | A0A7I2V448_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 453 | Annotation score: | ||
A0A7I2V5I2 | A0A7I2V5I2_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 612 | Annotation score: | ||
A0A7I2V534 | A0A7I2V534_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 369 | Annotation score: | ||
H0YIZ7 | H0YIZ7_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 465 | Annotation score: | ||
B7Z5N7 | B7Z5N7_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 457 | Annotation score: | ||
G3V5F3 | G3V5F3_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 121 | Annotation score: | ||
A0A7I2V590 | A0A7I2V590_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 532 | Annotation score: | ||
A0A7I2V320 | A0A7I2V320_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 572 | Annotation score: | ||
A0A7I2V3B4 | A0A7I2V3B4_HUMAN | Sec1 family domain-containing prote... | SCFD1 | 620 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL121852 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000678402.1; ENSP00000503444.1; ENSG00000092108.22 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL121852 Genomic DNA No translation available. |
3D structure databases
SMRi | A0A7I2V3G4 |
ModBasei | Search... |
Proteomic databases
PeptideAtlasi | A0A7I2V3G4 |
Genome annotation databases
Ensembli | ENST00000678402.1; ENSP00000503444.1; ENSG00000092108.22 |
Organism-specific databases
HGNCi | HGNC:20726, SCFD1 |
OpenTargetsi | ENSG00000092108 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00550000074845 |
Family and domain databases
Gene3Di | 3.40.50.1910, 1 hit 3.90.830.10, 1 hit |
InterProi | View protein in InterPro IPR043127, Sec-1-like_dom3a IPR001619, Sec1-like IPR027482, Sec1-like_dom2 IPR036045, Sec1-like_sf |
PANTHERi | PTHR11679, PTHR11679, 2 hits |
Pfami | View protein in Pfam PF00995, Sec1, 2 hits |
PIRSFi | PIRSF005715, VPS45_Sec1, 2 hits |
SUPFAMi | SSF56815, SSF56815, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A7I2V3G4_HUMAN | |
Accessioni | A0A7I2V3G4Primary (citable) accession number: A0A7I2V3G4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 7, 2021 |
Last sequence update: | April 7, 2021 | |
Last modified: | May 25, 2022 | |
This is version 4 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |