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Entry version 4 (02 Jun 2021)
Sequence version 1 (02 Dec 2020)
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Protein

Microtubule-associated protein

Gene

Map2

Organism
Mus caroli (Ryukyu mouse) (Ricefield mouse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Microtubule-associated proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Map2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus caroli (Ryukyu mouse) (Ricefield mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10089 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000515126 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini376 – 1510MAP2_projctnInterPro annotationAdd BLAST1135

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 86DisorderedSequence analysisAdd BLAST86
Regioni110 – 380DisorderedSequence analysisAdd BLAST271
Regioni402 – 495DisorderedSequence analysisAdd BLAST94
Regioni512 – 543DisorderedSequence analysisAdd BLAST32
Regioni591 – 686DisorderedSequence analysisAdd BLAST96
Regioni764 – 795DisorderedSequence analysisAdd BLAST32
Regioni823 – 863DisorderedSequence analysisAdd BLAST41
Regioni929 – 986DisorderedSequence analysisAdd BLAST58
Regioni1005 – 1035DisorderedSequence analysisAdd BLAST31
Regioni1087 – 1167DisorderedSequence analysisAdd BLAST81
Regioni1206 – 1228DisorderedSequence analysisAdd BLAST23
Regioni1304 – 1373DisorderedSequence analysisAdd BLAST70
Regioni1407 – 1465DisorderedSequence analysisAdd BLAST59
Regioni1475 – 1494DisorderedSequence analysisAdd BLAST20
Regioni1512 – 1640DisorderedSequence analysisAdd BLAST129
Regioni1809 – 1833DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi176 – 215Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi224 – 249Polar residuesSequence analysisAdd BLAST26
Compositional biasi259 – 273Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi361 – 380Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi418 – 434Polar residuesSequence analysisAdd BLAST17
Compositional biasi435 – 464Basic and acidic residuesSequence analysisAdd BLAST30
Compositional biasi479 – 493Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi522 – 543Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi623 – 643Polar residuesSequence analysisAdd BLAST21
Compositional biasi664 – 682Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi775 – 790Polar residuesSequence analysisAdd BLAST16
Compositional biasi947 – 986Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi1106 – 1164Basic and acidic residuesSequence analysisAdd BLAST59
Compositional biasi1320 – 1344Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi1354 – 1373Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi1565 – 1580Polar residuesSequence analysisAdd BLAST16
Compositional biasi1587 – 1622Polar residuesSequence analysisAdd BLAST36
Compositional biasi1811 – 1833Polar residuesSequence analysisAdd BLAST23

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030797, MAP2
IPR013588, MAP2_projctn
IPR001084, MAP_tubulin-bd_rpt

The PANTHER Classification System

More...
PANTHERi
PTHR11501:SF15, PTHR11501:SF15, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08377, MAP2_projctn, 1 hit
PF00418, Tubulin-binding, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00229, TAU_MAP_1, 2 hits
PS51491, TAU_MAP_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A6P7R563-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADERKDEGK APHWTSASLT EAAAHPHSPE MKDQGGAGEG LSRNANGFPY
60 70 80 90 100
REEEEGAFGE HRSQGTYSDT KENGINGELT SADRETAEEV SARIVQVVTA
110 120 130 140 150
EAVAVLKGEQ EKEAQYKDQP AALPLAAEET ANLPPSPPPS PASEQTATVE
160 170 180 190 200
EDLLTASKME FPEQQKFPSS FAEPLDKGEM EFKMPSKPGE DFEHAALVPD
210 220 230 240 250
TSKTPQDKKD LQGMEGEKLP PTPFAQTFGT NLEDRKQSTE PSISMPSIGL
260 270 280 290 300
SAEPSAPKEP KDWFIEMPTE SKKDEWGLAA PISPGPLTPM REKDVLEDIP
310 320 330 340 350
RWEGKQFDSP MPSPFHGGSF TLPLDTMKNE RVSEGPRPFA PIFFQSDDKV
360 370 380 390 400
SLQDPSALAT SKESSKDEEP QKDKADKMAD VSISEVTTLL GNVHSPVVEG
410 420 430 440 450
YVGENISGED KVTTNQEKKE TSVPSVQEPT LTETEPQTKL EEKSTVSIEE
460 470 480 490 500
AVAKEEESLK LRDDKTGVIQ TSTEQSFSKE DQKGQEHTID ELKQDSFPIS
510 520 530 540 550
LEQAVTDAAM TSKTLGKVSS EPEAVSERRE IQGLFEEKTA DKNKLEGAGT
560 570 580 590 600
ATITEVEMPF YEDKSGMSKY FETSALKEDM ARSTELGSDY YELSDSRGSA
610 620 630 640 650
QESLDTISPK NQHDEKELQA KASQPSPPAQ EAGYSTLAQS YTPDHPSELP
660 670 680 690 700
EEPSSPQERM FTIDPKVYGE KRDLHSKNKD DLTLSRSLGL GGRSAIEQRS
710 720 730 740 750
MSINLPMSCL DSIALGFNFG RGHDLSPLAS DILTNTSGSM DEGDDYLPPT
760 770 780 790 800
TPAVEKMPCF PIESKEEEDK AEPTKVTGGQ TTQVETSSES PFPAKEYYKN
810 820 830 840 850
GTVMAPDLPE MLDLAGTRSR LASVSADAEV ARRKSVPSEA MLAESSASLP
860 870 880 890 900
PVADESPVTV KPDSQLEDMG YCVFNKYTVP LPSPVQDSEN LSGESGSFYE
910 920 930 940 950
GTDDKVRRDL ATDLSLIEVK LAAAGRVKDE FTAEKEASPP TSADKSGLSR
960 970 980 990 1000
EFDHDRKAND KLDTVLEKSE EHLDSKEHVK ESEEMGDKVE LFGLGITYDQ
1010 1020 1030 1040 1050
TSTKELITTK DTSPEKTEKG LSSVPEVAEV EPTTKADQGL DFAAKKAESS
1060 1070 1080 1090 1100
QLDIKVSDFG QMASGMNVDA GKAIELKFEV AQELTLSSEA PQEADSFMGV
1110 1120 1130 1140 1150
ESGHTKEGVK VNETEVKEKV TKPDLVHQEA VDKEESYESS GEHESLTMES
1160 1170 1180 1190 1200
LKPDEGKKET SPETSLIQDE VALKLSVEIP CPPPVSEADL STDEKGEVQM
1210 1220 1230 1240 1250
EFIQLPKEES TETPDIPAIP SDVTQPQPEA IVSEPAEVPS EEEEIEAGGE
1260 1270 1280 1290 1300
YDKLLFRSDT LQISDLLVSG SREEFVETCP GEHKGVVESV VTIEDDFITV
1310 1320 1330 1340 1350
VQTTTDEGES GSHSVRFAAP AQPEEERRPC PHDEELEVEM AAEAQAEPKD
1360 1370 1380 1390 1400
GSPDAPATPE KEEVAFSEYK TETYDDYKDE TTIDDSIMDA DSLWVDTQDD
1410 1420 1430 1440 1450
DRSILTEQLE TIPKEERAEK EARRPSLEKH RKEKPFKTGR GRISTPERKV
1460 1470 1480 1490 1500
AKKEPSTVSR DEVRRKKAVY KKAELAKKSE VQAHSPSRKL ILKPAIKYTR
1510 1520 1530 1540 1550
PTHLSCVKRK TTAASGELAQ APSAFKQAKD KVTDGITKSP EKRSSLPRPS
1560 1570 1580 1590 1600
SILPPRRGVS GDREEHSFSL NSSISSARRT TRSEPIRRAG KSGTSTPTTP
1610 1620 1630 1640 1650
GSTAITPGTP PSYSSRTPGT PGTPSYPRTP GTPKSGILVP SEKKVAIIRT
1660 1670 1680 1690 1700
PPKSPATPKQ LRLINQPLPD LKNVKSKIGS TDNIKYQPKG GQVRILNKKI
1710 1720 1730 1740 1750
DFSKVQSRCG SKDNIKHSAG GGNVQIVTKK IDLSHVTSKC GSLKNIRHRP
1760 1770 1780 1790 1800
GGGRVKIESV KLDFKEKAQA KVGSLDNAHH VPGGGNVKID SQKLNFREHA
1810 1820 1830 1840 1850
KARVDHGAEI ITQSPSRSSV ASPRRLSNVS SSGSINLLES PQLATLAEDV

TAALAKQGL
Length:1,859
Mass (Da):202,562
Last modified:December 2, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE5032FC1AA29EB08
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_029332790.1, XM_029476930.1
XP_029332792.1, XM_029476932.1
XP_029332796.1, XM_029476936.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_029332790.1, XM_029476930.1
XP_029332792.1, XM_029476932.1
XP_029332796.1, XM_029476936.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR030797, MAP2
IPR013588, MAP2_projctn
IPR001084, MAP_tubulin-bd_rpt
PANTHERiPTHR11501:SF15, PTHR11501:SF15, 2 hits
PfamiView protein in Pfam
PF08377, MAP2_projctn, 1 hit
PF00418, Tubulin-binding, 4 hits
PROSITEiView protein in PROSITE
PS00229, TAU_MAP_1, 2 hits
PS51491, TAU_MAP_2, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6P7R563_MUSCR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6P7R563
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 2, 2020
Last sequence update: December 2, 2020
Last modified: June 2, 2021
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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