UniProtKB - A0A6M6PA06 (A0A6M6PA06_ECOBB)
Protein
Alkyl hydroperoxide reductase C
Gene
ahpC
Organism
Escherichia coli (strain B / BL21)
Status
Functioni
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.UniRule annotation
Catalytic activityi
- EC:1.11.1.26UniRule annotationARBA annotation
Keywordsi
Molecular function | AntioxidantUniRule annotation, Oxidoreductase, PeroxidaseUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Alkyl hydroperoxide reductase CUniRule annotationARBA annotation (EC:1.11.1.26UniRule annotationARBA annotation)Alternative name(s): PeroxiredoxinUniRule annotation Thioredoxin peroxidaseUniRule annotation |
Gene namesi | Name:ahpCImported ORF Names:HO397_02860Imported |
Organismi | Escherichia coli (strain B / BL21)Imported |
Taxonomic identifieri | 511693 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Subcellular locationi
- Cytoplasm UniRule annotationARBA annotation
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Homodimer.
UniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 157 | ThioredoxinInterPro annotationAdd BLAST | 156 |
Sequence similaritiesi
Keywords - Domaini
Redox-active centerUniRule annotationFamily and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR017559, AhpC IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
PANTHERi | PTHR10681:SF121, PTHR10681:SF121, 1 hit |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
TIGRFAMsi | TIGR03137, AhpC, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A6M6PA06-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLINTKIKP FKNQAFKNGE FIEITEKDTE GRWSVFFFYP ADFTFVCPTE
60 70 80 90 100
LGDVADHYEE LQKLGVDVYA VSTDTHFTHK AWHSSSETIA KIKYAMIGDP
110 120 130 140 150
TGALTRNFDN MREDEGLADR ATFVVDPQGI IQAIEVTAEG IGRDASDLLR
160 170 180
KIKAAQYVAS HPGEVCPAKW KEGEATLAPS LDLVGKI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP053601 Genomic DNA Translation: QJZ03116.1 |
RefSeqi | WP_000052796.1, NZ_CP053601.1 |
Genome annotation databases
GeneIDi | 49585628 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP053601 Genomic DNA Translation: QJZ03116.1 |
RefSeqi | WP_000052796.1, NZ_CP053601.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 49585628 |
Family and domain databases
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR017559, AhpC IPR000866, AhpC/TSA IPR024706, Peroxiredoxin_AhpC-typ IPR019479, Peroxiredoxin_C IPR036249, Thioredoxin-like_sf IPR013766, Thioredoxin_domain |
PANTHERi | PTHR10681:SF121, PTHR10681:SF121, 1 hit |
Pfami | View protein in Pfam PF10417, 1-cysPrx_C, 1 hit PF00578, AhpC-TSA, 1 hit |
PIRSFi | PIRSF000239, AHPC, 1 hit |
SUPFAMi | SSF52833, SSF52833, 1 hit |
TIGRFAMsi | TIGR03137, AhpC, 1 hit |
PROSITEi | View protein in PROSITE PS51352, THIOREDOXIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A6M6PA06_ECOBB | |
Accessioni | A0A6M6PA06Primary (citable) accession number: A0A6M6PA06 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 7, 2020 |
Last sequence update: | October 7, 2020 | |
Last modified: | December 2, 2020 | |
This is version 2 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |