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UniProtKB - A0A6M3ZEB4 (A0A6M3ZEB4_BACSU)
Protein
Chitosanase
Gene
HIR78_15815
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
UniRule annotationCatalytic activityi
- Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan.UniRule annotation EC:3.2.1.132
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 54 | Proton donorUniRule annotation | 1 | |
Active sitei | 70 | NucleophileUniRule annotation | 1 |
GO - Molecular functioni
- chitosanase activity Source: UniProtKB-UniRule
GO - Biological processi
- carbohydrate metabolic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | GlycosidaseUniRule annotation, Hydrolase |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:HIR78_15815Imported |
Organismi | Bacillus subtilis (strain 168)Imported |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Subcellular locationi
Extracellular region or secreted
- Secreted UniRule annotation
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedUniRule annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 35 | Sequence analysisAdd BLAST | 35 | |
ChainiPRO_5030158730 | 36 – 277 | ChitosanaseSequence analysisAdd BLAST | 242 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycosyl hydrolase 46 family.UniRule annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
OMAi | AQNDERD |
Family and domain databases
CDDi | cd00978, chitosanase_GH46, 1 hit |
Gene3Di | 3.30.386.10, 1 hit |
InterProi | View protein in InterPro IPR000400, Glyco_hydro_46 IPR023099, Glyco_hydro_46_N IPR023346, Lysozyme-like_dom_sf |
Pfami | View protein in Pfam PF01374, Glyco_hydro_46, 1 hit |
PIRSFi | PIRSF036551, Chitosanase, 1 hit |
SUPFAMi | SSF53955, SSF53955, 1 hit |
PROSITEi | View protein in PROSITE PS60000, CHITOSANASE_46_80, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A6M3ZEB4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKISMQKADF WKKAAISLLV FTMFFTLMMS ETVFAAGLNK DQKRRAEQLT
60 70 80 90 100
SIFENGTTEI QYGYVERLDD GRGYTCGRAG FTTATGDALE VVEVYTKAVP
110 120 130 140 150
NNKLKKYLPE LRRLAKEESD DTSNLKGFAS AWKSLANDKE FRAAQDKVND
160 170 180 190 200
HLYYQPAMKR SDNAGLKTAL ARAVMYDTVI QHGDGDDPDS FYALIKRTNK
210 220 230 240 250
KAGGSPKDGI DEKKWLNKFL DVRYDDLMNP ANHDTRDEWR ESVARVDVLR
260 270
SIAKENNYNL NGPIHVRSNE YGNFVIK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP052842 Genomic DNA Translation: QJP89408.1 |
RefSeqi | NP_390566.1, NC_000964.3 WP_003229851.1, NZ_JNCM01000036.1 |
Genome annotation databases
GeneIDi | 936802 |
KEGGi | bsu:BSU26890 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP052842 Genomic DNA Translation: QJP89408.1 |
RefSeqi | NP_390566.1, NC_000964.3 WP_003229851.1, NZ_JNCM01000036.1 |
3D structure databases
SMRi | A0A6M3ZEB4 |
ModBasei | Search... |
Genome annotation databases
GeneIDi | 936802 |
KEGGi | bsu:BSU26890 |
Phylogenomic databases
OMAi | AQNDERD |
Family and domain databases
CDDi | cd00978, chitosanase_GH46, 1 hit |
Gene3Di | 3.30.386.10, 1 hit |
InterProi | View protein in InterPro IPR000400, Glyco_hydro_46 IPR023099, Glyco_hydro_46_N IPR023346, Lysozyme-like_dom_sf |
Pfami | View protein in Pfam PF01374, Glyco_hydro_46, 1 hit |
PIRSFi | PIRSF036551, Chitosanase, 1 hit |
SUPFAMi | SSF53955, SSF53955, 1 hit |
PROSITEi | View protein in PROSITE PS60000, CHITOSANASE_46_80, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A6M3ZEB4_BACSU | |
Accessioni | A0A6M3ZEB4Primary (citable) accession number: A0A6M3ZEB4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 7, 2020 |
Last sequence update: | October 7, 2020 | |
Last modified: | September 29, 2021 | |
This is version 5 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |