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UniProtKB - A0A6J3BMQ0 (A0A6J3BMQ0_VICPA)
Protein
Submitted name:
ankyrin-2 isoform X24
Gene
ANK2
Organism
Vicugna pacos (Alpaca) (Lama pacos)
Status
Names & Taxonomyi
Protein namesi | Submitted name: ankyrin-2 isoform X24Imported |
Gene namesi | Name:ANK2Imported |
Organismi | Vicugna pacos (Alpaca) (Lama pacos)Imported |
Taxonomic identifieri | 30538 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Tylopoda › Camelidae › Vicugna |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- cytoskeleton ARBA annotation
Other locations
- Membrane ARBA annotation
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Other locations
- membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cytoplasm, CytoskeletonARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 63 – 95 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 96 – 128 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 129 – 161 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 232 – 264 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 265 – 297 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 298 – 330 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 331 – 363 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 364 – 396 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 397 – 429 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 430 – 462 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 463 – 495 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 496 – 528 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 529 – 561 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 562 – 594 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 595 – 627 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 628 – 660 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 661 – 693 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 694 – 726 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 727 – 759 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 760 – 792 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Domaini | 980 – 1168 | ZU5InterPro annotationAdd BLAST | 189 | |
Domaini | 1170 – 1316 | ZU5InterPro annotationAdd BLAST | 147 | |
Domaini | 1496 – 1580 | DeathInterPro annotationAdd BLAST | 85 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 34 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 1470 – 1493 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 1615 – 1637 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 1671 – 1778 | DisorderedSequence analysisAdd BLAST | 108 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 8 – 31 | Basic and acidic residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 1615 – 1636 | Basic and acidic residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 1671 – 1724 | Polar residuesSequence analysisAdd BLAST | 54 | |
Compositional biasi | 1750 – 1766 | Basic and acidic residuesSequence analysisAdd BLAST | 17 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationFamily and domain databases
Gene3Di | 1.10.533.10, 1 hit 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR040745, Ankyrin_UPA IPR011029, DEATH-like_dom_sf IPR000488, Death_domain IPR000906, ZU5_dom |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 7 hits PF13637, Ank_4, 2 hits PF00531, Death, 1 hit PF17809, UPA_2, 1 hit PF00791, ZU5, 2 hits |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 23 hits SM00005, DEATH, 1 hit SM00218, ZU5, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit SSF48403, SSF48403, 3 hits |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 20 hits PS50017, DEATH_DOMAIN, 1 hit PS51145, ZU5, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 49 potential isoforms that are computationally mapped.Show allAlign All
A0A6J3BMQ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMNEDAAQKS DSGEKFNGGS QRRKRPKKSD SNASFLRAAR AGNLDKVVEY
60 70 80 90 100
LKGGIDINTC NQNGLNALHL AAKEGHVGLV QELLGRGSAV DSATKKGNTA
110 120 130 140 150
LHIASLAGQA EVVKVLVKEG ANINAQSQNG FTPLYMAAQE NHIDVVKYLL
160 170 180 190 200
ENGANQSTAT EDGFTPLAVA LQQGHNQAVA ILLENDTKGK VRLPALHIAA
210 220 230 240 250
RKDDTKSAAL LLQNDHNADV QSKMMVNRTT ESGFTPLHIA AHYGNVNVAT
260 270 280 290 300
LLLNRGAAVD FTARNGITPL HVASKRGNTN MVKLLLDRGG QIDAKTRDGL
310 320 330 340 350
TPLHCAARSG HDQVVELLLE RGAPLLARTK NGLSPLHMAA QGDHVECVKH
360 370 380 390 400
LLQHKAPVDD VTLDYLTALH VAAHCGHYRV TKLLLDKRAN PNARALNGFT
410 420 430 440 450
PLHIACKKNR IKVMELLVKY GASIQAITES GLTPIHVAAF MGHLNIVLLL
460 470 480 490 500
LQNGASPDVT NIRGETALHM AARAGQVEVV RCLLRNGALV DARAREEQTP
510 520 530 540 550
LHIASRLGKT EIVQLLLQHM AHPDAATTNG YTPLHISARE GQVDVASVLL
560 570 580 590 600
EAGAAHSLAT KKGFTPLHVA AKYGSLDVAK LLLQRRAAAD SAGKNGLTPL
610 620 630 640 650
HVAAHYDNQK VALLLLEKGA SPHATAKNGY TPLHIAAKKN QMQIASTLLN
660 670 680 690 700
YGAETNIVTK QGVTPLHLAS QEGHTDMVTL LLDKGANIHM STKSGLTSLH
710 720 730 740 750
LAAQEDKVNV ADILTKHGAD QDAHTKLGYT PLIVACHYGN VKMVNFLLKQ
760 770 780 790 800
GANVNAKTKN GYTPLHQAAQ QGHTHIINVL LQHGAKPNAT TANGNTALAI
810 820 830 840 850
AKRLGYISVV DTLKVVTEEV TTTTTTITEK HKLNVPETMT EVLDVSDEEG
860 870 880 890 900
DDTMTGDGGE YLRPEDLKEL GDDSLPSSQF LDGMNYLRYS LEGGRSDSLR
910 920 930 940 950
SFSSDRSHTL SHASYLRDSA MIDDTVVIPS HQVSTLAKEA ERNSYRLSWG
960 970 980 990 1000
TENLDNVALS SSPIHSGRTS PCLDRDSSSF LVSFMVDARG GAMRGCRHNG
1010 1020 1030 1040 1050
LRIIIPPRKC TAPTRVTCRL VKRHRLATMP PMVEGEGLAS RLIEVGPSGA
1060 1070 1080 1090 1100
QFLGKLHLPT APPPLNEGES LVSRILQLGP PGTKFLGPVI VEIPHFAALR
1110 1120 1130 1140 1150
GKERELVVLR SENGDSWKEH YCEYTEDELN EILNGMDEVL DSPEDLEKKR
1160 1170 1180 1190 1200
ICRIITRDFP QYFAVVSRIK QDSNLIGPEG GVLSSTVVPQ VQAVFPEGAL
1210 1220 1230 1240 1250
TKRIRVGLQA QPMHSELVKK ILGNKATFSP IVTLEPRRRK FHKPITMTIP
1260 1270 1280 1290 1300
VPKASSDVML NGFGGDAPTL RLLCSITGGT TPAQWEDITG TTPLTFVNEC
1310 1320 1330 1340 1350
VSFTTNVSAR FWLIDCRQIQ ESVTFASQVY REIICVPYMA KFVVFAKSHD
1360 1370 1380 1390 1400
PIEARLRCFC MTDDKVDKTL EQQENFAEVA RSRDVEVLEG KPIYVDCFGN
1410 1420 1430 1440 1450
LVPLTKSGQH HIFSFFAFKE NRLPLFVKVR DTTQEPCGRL SFMKEPKSTR
1460 1470 1480 1490 1500
GLVHQAICNL NITLPIYTKE SESDQEQEEE IDMTSEKNQQ AEQERIEERL
1510 1520 1530 1540 1550
AYIADHLGFS WTELARELDF TEEQIHQIRI ENPNSLQDQS HALLKYWLER
1560 1570 1580 1590 1600
DGKHATDTSL IECLTKINRM DIVHLMETST EPLQERISHS YAEIEHTITL
1610 1620 1630 1640 1650
DHSEGFSVLQ EELCAAQHKQ KEEQADSKEG DHPPIVSEED ISVGYSTFQD
1660 1670 1680 1690 1700
SIPKTEGDSS ATEHLPLTHQ EHAQQDFSGK MQDQPEESSL EQQEYFVTTP
1710 1720 1730 1740 1750
GTEVSETQKA TAVPGSPSQT PEEVSSPAEE ERPYPHTLTS SGRGDSPIVQ
1760 1770 1780 1790 1800
EPEEPPERRE EGSPRKSSLV IVESAEDQPR AFERLDEEAA FQKELTEELG
1810 1820 1830 1840 1850
ELEASSDEEA MLTTRVVRRR VIIQGEDMPD IPPESVTEEE YVDERGHTVV
1860 1870 1880 1890 1900
KKVTRKIIRR YVSSDGVEKE EITMQGMPQD PVNIEEGDGY SKVIKRIVLK
1910
SDMEQSEDNH E
Computationally mapped potential isoform sequencesi
There are 49 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A6I9IGW9 | A0A6I9IGW9_VICPA | ankyrin-2 isoform X11 | ANK2 | 3,954 | Annotation score: | ||
A0A6J0ARX9 | A0A6J0ARX9_VICPA | ankyrin-2 isoform X9 | ANK2 | 4,112 | Annotation score: | ||
A0A6J0AT39 | A0A6J0AT39_VICPA | ankyrin-2 isoform X7 | ANK2 | 4,117 | Annotation score: | ||
A0A6J0ATX4 | A0A6J0ATX4_VICPA | ankyrin-2 isoform X3 | ANK2 | 4,162 | Annotation score: | ||
A0A6J0ATY0 | A0A6J0ATY0_VICPA | ankyrin-2 isoform X10 | ANK2 | 4,102 | Annotation score: | ||
A0A6J0AUL1 | A0A6J0AUL1_VICPA | ankyrin-2 isoform X4 | ANK2 | 4,150 | Annotation score: | ||
A0A6J0AW57 | A0A6J0AW57_VICPA | ankyrin-2 isoform X6 | ANK2 | 4,133 | Annotation score: | ||
A0A6J0AW62 | A0A6J0AW62_VICPA | ankyrin-2 isoform X8 | ANK2 | 4,109 | Annotation score: | ||
A0A6J3BIP9 | A0A6J3BIP9_VICPA | ankyrin-2 isoform X2 | ANK2 | 4,179 | Annotation score: | ||
A0A6J3BMK4 | A0A6J3BMK4_VICPA | ankyrin-2 isoform X5 | ANK2 | 4,135 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
RefSeqi | XP_031547008.1, XM_031691148.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_031547008.1, XM_031691148.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
Gene3Di | 1.10.533.10, 1 hit 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR040745, Ankyrin_UPA IPR011029, DEATH-like_dom_sf IPR000488, Death_domain IPR000906, ZU5_dom |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 7 hits PF13637, Ank_4, 2 hits PF00531, Death, 1 hit PF17809, UPA_2, 1 hit PF00791, ZU5, 2 hits |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 23 hits SM00005, DEATH, 1 hit SM00218, ZU5, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit SSF48403, SSF48403, 3 hits |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 20 hits PS50017, DEATH_DOMAIN, 1 hit PS51145, ZU5, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A6J3BMQ0_VICPA | |
Accessioni | A0A6J3BMQ0Primary (citable) accession number: A0A6J3BMQ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 7, 2020 |
Last sequence update: | October 7, 2020 | |
Last modified: | January 19, 2022 | |
This is version 6 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |