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UniProtKB - A0A6J2RH64 (A0A6J2RH64_COTGO)

Entry version 3 (10 Feb 2021)
Sequence version 1 (07 Oct 2020)
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Protein
Submitted name:

collagen alpha-1(XVIII) chain-like isoform X3

Gene

LOC115022564

Organism
Cottoperca gobio (Frogmouth) (Aphritis gobio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
collagen alpha-1(XVIII) chain-like isoform X3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOC115022564Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCottoperca gobio (Frogmouth) (Aphritis gobio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri56716 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Eupercaria › Perciformes › Notothenioidei › Bovichtidae › Cottoperca
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000504630 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini74 – 263LAM_G_DOMAINInterPro annotationAdd BLAST190

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 55DisorderedSequence analysisAdd BLAST55
Regioni264 – 699DisorderedSequence analysisAdd BLAST436
Regioni736 – 1029DisorderedSequence analysisAdd BLAST294
Regioni1075 – 1111DisorderedSequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi13 – 47PolarSequence analysisAdd BLAST35
Compositional biasi292 – 311PolyampholyteSequence analysisAdd BLAST20
Compositional biasi344 – 370PolyampholyteSequence analysisAdd BLAST27
Compositional biasi374 – 394Pro-richSequence analysisAdd BLAST21
Compositional biasi459 – 473Pro-richSequence analysisAdd BLAST15
Compositional biasi501 – 515Pro-richSequence analysisAdd BLAST15
Compositional biasi592 – 610Pro-richSequence analysisAdd BLAST19
Compositional biasi1008 – 1022Pro-richSequence analysisAdd BLAST15
Compositional biasi1078 – 1111PolarSequence analysisAdd BLAST34

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

CollagenImportedARBA annotation

Family and domain databases

Conserved Domains Database

More...CDDi		cd00247, Endostatin-like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016186, C-type_lectin-like/link_sf
IPR008160, Collagen
IPR010515, Collagenase_NC10/endostatin
IPR013320, ConA-like_dom_sf
IPR016187, CTDL_fold
IPR001791, Laminin_G

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01391, Collagen, 6 hits
PF06482, Endostatin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00210, TSPN, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49899, SSF49899, 1 hit
SSF56436, SSF56436, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A6J2RH64-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVKGDRVTEN APEDSTLTEG SVLAPTPSPV SIFDHSTEEQ GTSPPEDNAG 
        60         70         80         90        100
GGSKHRVQYK PLKHWKSERG SGDHLDLTEL IGVPLPPFVS FTPGHESFPA 
       110        120        130        140        150
YNFGPDANIG RLTKTFVPGS FYRDFAIIVT VRPATQRGGV LFAITDALQK 
       160        170        180        190        200
VVELGLALTP VRGGLQSILL YYTDREQASH SHKAASFSVP DMTEQWTRFT 
       210        220        230        240        250
LVVEHDEVRL YMDCGEAERT TFHRSAERLN FSHNSGIFVA NAGGTGLDKF 
       260        270        280        290        300
VGSLQQLVIK DDPRAAEEQC EDDDPYASGY TSGDDALDDR ETEEEIMKNT 
       310        320        330        340        350
HERKHGTAQE EDSVPVRAPP TEAPEVELDE YSGHQTSTEA TEEIRGPHMT 
       360        370        380        390        400
EEPGERSGDG HVRHGLKGER GGPGPRGPPG PPGHPGPTPL PGQAQPGPRG 
       410        420        430        440        450
TQGTPGASGS PGLAGRDGQQ GNKGDKGDAG QRGSQGFPGL AGEAGTKGEK 
       460        470        480        490        500
GDQAVGVPGP PGLPGPPGPP RSRSVPYGAD ALGSGFEDLD SDTELIRGHP 
       510        520        530        540        550
GLPGPPGPPG PPGPLSDSDE DLSTAGAPGT PGKDGLTGKP GIPGPAGKDG 
       560        570        580        590        600
GPGLPGVVGE KGEQGLSGPL GPKGECGSLG TAGSSGPPGP SGPQGKRGPS 
       610        620        630        640        650
GPPGPPGPPG TKFFVEDMEG SGKSDMLIGA GVRGPQGPPG LPGAQGPKGE 
       660        670        680        690        700
DGATGAPALS VKGEPGDAGP EGLQGPAGLP GARGAKGEKG NLGPKGDQGV 
       710        720        730        740        750
DGLCIPGPPG PPGPIINLSD LLLNVTDGIF NFTEIRGPPG SVGPEGLPGR 
       760        770        780        790        800
AGFPGPRGPK GDLGPPGVQG PAGFKGEKGE PGVTIAADGS LLSSPKGPQG 
       810        820        830        840        850
PKGIKGDRGF PGSSGLMGPI GPSGQKGEYG FPGRPGRSGL PGRKGDKADS 
       860        870        880        890        900
VGLPGPRGLP GPPGNPGKII GLKGTVFPVR PRPHCKMGRS GTWEESVGAK 
       910        920        930        940        950
GDKGDEGIPG EPGTLAPVFP EGFVGARGDQ GYQGQKGEKG DGGLPGPPGL 
       960        970        980        990       1000
PGRSGLVGPK GESIVGPQGP VGSVGQPGAP GFGRPGSRGS PGPAGPPGYA 
      1010       1020       1030       1040       1050
PAYGSDVNVP GPPGPPGPTG SPGYANPVTT YKTSHALSRE TQRAAEGTLA 
      1060       1070       1080       1090       1100
YVSEKGGELY IRARNGWRKI QLGELIHPGP SSSATSQSLS RTGELSRPQR 
      1110       1120       1130       1140       1150
IHSQELQESS RGYQPSYNVL PQTFNAVPGL HMVALNTPLK GDMRGIRGAD 
      1160       1170       1180       1190       1200
FQCYQQARSM GLTATYRAFL SSHLQDLATI VRKADRTDMP VVNFRGEVLF 
      1210       1220       1230       1240       1250
SSWMSIFSGN GGTFNPSTPI YSFDGRNVMT DSAWPEKLVW HGSNTVGIRL 
      1260       1270       1280       1290       1300
TTNYCEAWRT ADIAVTGQAA LLQTGRLLGQ HTRSCSNHYI VLCIENTYVG 

NKHQKRT
Length:1,307
Mass (Da):134,087
Last modified:October 7, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC668B4BAD71F2986
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6J2RF03A0A6J2RF03_COTGO
collagen alpha-1(XVIII) chain-like ...
LOC115022564
1,266Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J2RF00A0A6J2RF00_COTGO
collagen alpha-1(XVIII) chain-like ...
LOC115022564
1,307Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J2RGX1A0A6J2RGX1_COTGO
collagen alpha-1(XVIII) chain-like ...
LOC115022564
1,293Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J2RIX2A0A6J2RIX2_COTGO
collagen alpha-1(XVIII) chain-like ...
LOC115022564
1,308Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J2RIX8A0A6J2RIX8_COTGO
collagen alpha-1(XVIII) chain-like ...
LOC115022564
1,292Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J2RJC2A0A6J2RJC2_COTGO
collagen alpha-1(XVIII) chain-like ...
LOC115022564
1,296Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_029309454.1, XM_029453594.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_029309454.1, XM_029453594.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

CDDicd00247, Endostatin-like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186, C-type_lectin-like/link_sf
IPR008160, Collagen
IPR010515, Collagenase_NC10/endostatin
IPR013320, ConA-like_dom_sf
IPR016187, CTDL_fold
IPR001791, Laminin_G
PfamiView protein in Pfam
PF01391, Collagen, 6 hits
PF06482, Endostatin, 1 hit
SMARTiView protein in SMART
SM00210, TSPN, 1 hit
SUPFAMiSSF49899, SSF49899, 1 hit
SSF56436, SSF56436, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6J2RH64_COTGO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6J2RH64
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 7, 2020
Last sequence update: October 7, 2020
Last modified: February 10, 2021
This is version 3 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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