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Entry version 2 (02 Dec 2020)
Sequence version 2 (02 Dec 2020)
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Protein
Submitted name:

zinc finger protein 106 isoform X1

Gene

ZNF106

Organism
Zalophus californianus (California sealion)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
zinc finger protein 106 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF106Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiZalophus californianus (California sealion)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9704 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaOtariidaeZalophus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000515165 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

WD repeatPROSITE-ProRule annotationARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type

The PANTHER Classification System

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PANTHERi
PTHR14435, PTHR14435, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF00400, WD40, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A6J2B1I6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVRERKCILC HIVYSSKKEM DEHMRSMLHH RELENLKGRD SSHECRVCGV
60 70 80 90 100
TEVGLSAYAK HISSQLHKDN VDAQDREDDG KGEEEEEDYF DKELVQLIKQ
110 120 130 140 150
RKEQSRQEEP SNSSQEISSD DRRPQWRRED RIPYQDREGY SQPAWHHRGP
160 170 180 190 200
PQRDWKWEKD GFNNNRKNNF PHSLRNNGGP RGCSGWHKGV AGGASTWFHN
210 220 230 240 250
HSNSGGGWHS KSGAVDWNPN GTGRNSSWHS EGTGGFSSWH MNSSNGNWKS
260 270 280 290 300
SVRSTNSWNY SGPGDKFQPG RNRNSNCQMD DLTMLWNKKS KSNKYNQERY
310 320 330 340 350
SWQRQESDKI GTAATYRGPS EGFTADKFPS EGLLSFSFEQ LESKTTKQTD
360 370 380 390 400
PIASKMGGKN GSVARDKLHR WTPYPPQKTL DLQSGMKEVT GNKSEMIDKP
410 420 430 440 450
FFDFSLTTAG TPEPQIDETN HSPTLKTQKE THGGSLTHKA PSDCTASYEA
460 470 480 490 500
VRDCPVTEKH EQELHLSKMP SLKSALLPIP VTKSVPQKPD LKNPSKNTKT
510 520 530 540 550
NSFFPGEHSN PLNKPAMEDS HGSHVTKLRS SCPHVLKGNK STFGTQREPD
560 570 580 590 600
ENFSDTLQKA KEVLQCHESL QNPLLGTSKR TRNFAKASRN VEESEKGSLK
610 620 630 640 650
IEFQVHTLED ESDGELSDTE KRGSKIGTLG SATTEMLSCS THLADEKEGD
660 670 680 690 700
DQNLKTCRKL STNACNSTIH QKEPELQMTS AASPPSGLLL DLKTSLEDAQ
710 720 730 740 750
VDDPVKSHVS YETEGFESAS LDAELQKNDL GQSSGPLLPE LSKLGFPASL
760 770 780 790 800
QRDLTRHISL KSKTGAHLPE PNLNSARRIR NISGHRKGET EKESGLKPTL
810 820 830 840 850
RQILNASRRN VNWEQVIQQV TKKKQELGKG LPRFGIEMVP LVQNEQEVLD
860 870 880 890 900
LDGEPDLSNL EGFQWEGISI SSSPGLARKR SLSESSVIMD RAPSVYSFFS
910 920 930 940 950
EEGTGKENEP QQIFSPSNSL RAAQSQTTTL GLKQEVTPLA ASLRTGERAE
960 970 980 990 1000
NVASQRRHSA QLSSDRAIPL MHLAKDLNSQ EGSTPSSENQ NTQESNGEGN
1010 1020 1030 1040 1050
SLSSNTSSAL GISSLADAAT DSSCTSGAEQ NDSQSVRKKR RATGDGSSPE
1060 1070 1080 1090 1100
LPSLERKNKR RKIKGKKERS QVDQLLNISL REEELSKSLQ CMDNNLLQAR
1110 1120 1130 1140 1150
AALQTAYVEV QRLLMLKQQI TMEMSALRTH RIQILQGLQE TYEPSERPDQ
1160 1170 1180 1190 1200
VPYSLPRERR NSRSQTSADA TLLPTPFFPV VLEPPSSHMS PSFTGVPLQV
1210 1220 1230 1240 1250
TTSPTFQAHG SVPAPDSSIQ IKQEPMSPEH DESVTAVSQG SAGNVSKELL
1260 1270 1280 1290 1300
QANRENSDSC PVYPVITATL SLSEVTESFH EPSQELKFSM EQGNTRNRGN
1310 1320 1330 1340 1350
APSSQPADLH EEPVKGNSGS EACTSSFPRL SFVSETPLER DPHSPADQPE
1360 1370 1380 1390 1400
QQAESTLTSA ETRGNKKKKK LRKKKTLRAA HVPENSDTEQ DVFTAKPVRK
1410 1420 1430 1440 1450
VKTGKSTKGG KVTTSTWEDS RTGPEQESVR DEPDSDSSLE VLEIPNPQLE
1460 1470 1480 1490 1500
VVAIDSSESG EEKPDSPSKK DIWNSAEQNS LETSRSGCDE VSSTSEIGTR
1510 1520 1530 1540 1550
YKDGIPVSVA ETQTVISSIK GSKNSSEISS EPGDDDEPTE GSFEGHQAAV
1560 1570 1580 1590 1600
NAIQIFGNLL YTCSADKTVR AYNLVSRKCI GVFEGHTSKV NCLLVTQTSG
1610 1620 1630 1640 1650
KNAALYTGSS DHTIRCYHVK TRECVEQLQL EDRVLCLHSR WRILYAGLAN
1660 1670 1680 1690 1700
GTVVTFNIKN NKRLEIFECH GPRAVSCLAT AQEGARKLLV VGSYDCTISV
1710 1720 1730 1740 1750
RDARNGLLLR TLEGHSKTIL CMKVVNDLVF SGSSDQSVHA HNIHTGELVR
1760 1770 1780 1790 1800
IYKGHNHAVT VVNILGKVMV TACLDKFVRV YELQSHDRLQ VYGGHKDMIM
1810 1820 1830 1840 1850
CMTIHKSMIY TGCYDGSIQA VRLNLMQNYR CWWHGCALIF GVVDHLKQHL
1860 1870 1880 1890
LTDHTNPNFQ TLKCRWKNCD AFFTARKGSK QDAAGHIERH AEDDSKIDS
Length:1,899
Mass (Da):210,670
Last modified:December 2, 2020 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC1A63B487C6A9B80
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_027425699.2, XM_027569898.2

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_027425699.2, XM_027569898.2

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type
PANTHERiPTHR14435, PTHR14435, 1 hit
PfamiView protein in Pfam
PF00400, WD40, 1 hit
SMARTiView protein in SMART
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6J2B1I6_ZALCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6J2B1I6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 7, 2020
Last sequence update: December 2, 2020
Last modified: December 2, 2020
This is version 2 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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