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Entry version 1 (07 Oct 2020)
Sequence version 1 (07 Oct 2020)
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Protein
Submitted name:

voltage-dependent R-type calcium channel subunit alpha-1E isoform X1

Gene

CACNA1E

Organism
Acinonyx jubatus (Cheetah)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
voltage-dependent R-type calcium channel subunit alpha-1E isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CACNA1EImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcinonyx jubatus (Cheetah)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri32536 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeAcinonychinaeAcinonyx
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000504626 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A6J2AP93-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVPEMRGPSP GRRLPEPAPC PAAGGNPEPW ALGRRHRHVL ALPEEEAWRP
60 70 80 90 100
QQCALLEADA SDEVGMLPAS PRAVAAGFDN FFPVQEGEGP GWEGGAALEA
110 120 130 140 150
GSSPFLPVSP EVMKRRRGGL IEQRDIIKAH EAHKMQSTPQ ARRKEWEMAR
160 170 180 190 200
FGEAVVGRPG SGDGDSDQSR NRQGTPVPAS GPAAAYKQSK AQRARTMALY
210 220 230 240 250
NPIPVRQNCF TVNRSLFIFG EDNIVRKYAK KLIDWPPFEY MILATIIANC
260 270 280 290 300
IVLALEQHLP EDDKTPMSRR LEKTEPYFIG IFCFEAGIKI VALGFIFHKG
310 320 330 340 350
SYLRNGWNVM DFIVVLSGIL ATAGTHFNTH VDLRTLRAVR VLRPLKLVSG
360 370 380 390 400
IPSLQIVLKS IMKAMVPLLQ IGLLLFFAIL MFAIIGLEFY SGKLHRACFT
410 420 430 440 450
NSSGILEGFD PPHPCGVQGC PAGYECKDWI GPNDGITQFD NILFAVLTVF
460 470 480 490 500
QCITMEGWTT VLYNTNDALG ATWNWLYFIP LIIIGSFFVL NLVLGVLSGE
510 520 530 540 550
FAKERERVEN RRAFMKLRRQ QQIERELNGY RAWIDKAEEV MLAEENKNAG
560 570 580 590 600
TSALEVLRRA TIKRSRTEAM TRDSSDEHCV DISSVGTPLA RASIKSAKVD
610 620 630 640 650
GASYFRHKER LLRISIRHMV KSQVFYWIVL SLVALNTACV AIVHHNQPQW
660 670 680 690 700
LTHLLYYAEF LFLGLFLLEM SLKMYGMGPR LYFHSSFNCF DFGVTVGSIF
710 720 730 740 750
EVVWAIFRPG TSFGISVLRA LRLLRIFKIT KYWASLRNLV VSLMSSMKSI
760 770 780 790 800
ISLLFLLFLF IVVFALLGMQ LFGGRFNFND GTPSANFDTF PAAIMTVFQI
810 820 830 840 850
LTGEDWNEVM YNGIRSQGGV SSGMWSAIYF IVLTLFGNYT LLNVFLAIAV
860 870 880 890 900
DNLANAQELT KDEQEEEEAF NQKHALQKAK EVSPMSAPNM PSIERDRRRR
910 920 930 940 950
HHMSMWEPRS SHLRERRRRH HMSVWEQRTS QLRRHMQMSS QEALNKEEAP
960 970 980 990 1000
PMNPLNPLNP LSPLNPLNAH PSLYRRPRPI EGLGLGLEKC EEERISRGGS
1010 1020 1030 1040 1050
LKGDGGDLPS ALDNQRSPLS LGKREPPWLA KPCHGNCDST QQEAGGGETV
1060 1070 1080 1090 1100
VTFEDRARHR QSQRRSRHRR VRTEGKEPSS TSRSRSASQE RSLDEGGPTE
1110 1120 1130 1140 1150
GEKDREPRAS HGGKEPTIQE EERGQDLRRT NSLMVPRGSG LAGALDEANT
1160 1170 1180 1190 1200
PLVQPQPELE MGKDTALTEQ EPEGSSEQAL LGDVQLDMGR AISQSEPDLS
1210 1220 1230 1240 1250
CVTANTDKAT TESTSVTVTI PDVGPLVDST VVHISNKTDG EASPLKEAEI
1260 1270 1280 1290 1300
KEEEEEVEKK QQKKEKRETG KAMVPHSSMF IFSTTNPIRR ACHYIVNLRY
1310 1320 1330 1340 1350
FEMCILLVIA ASSIALAAED PVLTNSERNK VLRYFDYVFT GVFTFEMVIK
1360 1370 1380 1390 1400
MIDQGLILQD GSYFRDLWNI LDFVVVVGAL VAFALANALG TNKGRDIKTI
1410 1420 1430 1440 1450
KSLRVLRVLR PLKTIKRLPK LKAVFDCVVT SLKNVFNILI VYKLFMFIFA
1460 1470 1480 1490 1500
VIAVQLFKGK FFYCTDSSKD TEKECIGNYV DHEKNKMEVK GREWKRHEFH
1510 1520 1530 1540 1550
YDNIIWALLT LFTVSTGEGW PQVLQHSVDV TEEDRGPSRS NRMEMSIFYV
1560 1570 1580 1590 1600
VYFVVFPFFF VNIFVALIII TFQEQGDKMM EECSLEKNER ACIDFAISAK
1610 1620 1630 1640 1650
PLTRYMPQNR HTFQYRVWHF VVSPSFEYTI MAMIALNTVV LMMKYYSAPC
1660 1670 1680 1690 1700
TYELALKYLN IAFTMVFSLE CVLKIIAFGF LNYFRDTWNI FDFITVIGSI
1710 1720 1730 1740 1750
TEIILTDSKL VNTSGFNMSF LKLFRAARLI KLLRQGYTIR ILLWTFVQSF
1760 1770 1780 1790 1800
KALPYVCLLI AMLFFIYAII GMQVFGNIKL DEESHINRHN NFRSFFGSLM
1810 1820 1830 1840 1850
LLFRSATGEA WQEIMLSCLG EKGCEPDTTA PSGQNENERC GTDLAYVYFV
1860 1870 1880 1890 1900
SFIFFCSFLM LNLFVAVIMD NFEYLTRDSS ILGPHHLDEF VRVWAEYDRA
1910 1920 1930 1940 1950
ACGRIHYTEM YEMLTLMSPP LGLGKRCPSK VAYKRLVLMN MPVAEDMTVH
1960 1970 1980 1990 2000
FTSTLMALIR TALDIKIAKG GADRQQLDSE LQKETLAIWP HLSQKMLDLL
2010 2020 2030 2040 2050
VPMPKASDLT VGKIYAAMMI MDYYKQSKVK KQRQQLEEQK NAPMFQRMEP
2060 2070 2080 2090 2100
SSLPQEIIAN AKALPYLQQD PVSGLSGRSG YPSMSPLSPQ EIFQLACMDP
2110 2120 2130 2140 2150
ADDGQFQEQQ SLEPEVSELK SVQSSNHGIY LPSDTQEHTG SGRASSMPRL
2160 2170 2180 2190 2200
TVDPQVVTDP SSMRRSFSTI RDKRSNSSWL EEFSMERSSE NTYKSRRRSY
2210 2220 2230 2240 2250
HSSLRLSAHR LNSDSGHKSD THRSGGRERG RSKERKHLLS PDVSRCNSEE
2260 2270 2280 2290 2300
RGTQADWESP ERHESRSPSE GRSQTPNRQG TGSLSESSIP SISDTSTPRR
2310 2320 2330 2340 2350
SRRQLPPVPP KPRPLLSYSS LIRHTGSMSP PADGSEGGSP LASQALESPE
2360 2370 2380 2390 2400
ASLAESSSSR HVQQGQHASP QRYISEPYLA LHEDSHASDC GEEETLTFEA
2410 2420 2430 2440 2450
AVATSLGRSN TIGSAPPLRH SWQMPNGHYR RRRRGGPGPG VMCGAVSDLL

SDTEEDDKC
Length:2,459
Mass (Da):277,178
Last modified:October 7, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i669194CECFAA6EBD
GO

Sequence databases

NCBI Reference Sequences

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RefSeqi
XP_026930210.1, XM_027074409.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_026930210.1, XM_027074409.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6J2AP93_ACIJB
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6J2AP93
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 7, 2020
Last sequence update: October 7, 2020
Last modified: October 7, 2020
This is version 1 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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