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Entry version 6 (19 Jan 2022)
Sequence version 1 (07 Oct 2020)
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Protein
Submitted name:

nesprin-1 isoform X8

Gene

SYNE1

Organism
Acinonyx jubatus (Cheetah)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
nesprin-1 isoform X8Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYNE1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAcinonyx jubatus (Cheetah)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri32536 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeAcinonychinaeAcinonyx
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000504626 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 8760CytoplasmicPROSITE-ProRule annotationAdd BLAST8760
Topological domaini8782 – 8811Perinuclear spacePROSITE-ProRule annotationAdd BLAST30

Keywords - Cellular componenti

Membrane, NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 141Calponin-homology (CH)InterPro annotationAdd BLAST115
Domaini185 – 290Calponin-homology (CH)InterPro annotationAdd BLAST106
Domaini8752 – 8811KASHInterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni5868 – 5895DisorderedSequence analysisAdd BLAST28
Regioni8258 – 8295DisorderedSequence analysisAdd BLAST38
Regioni8685 – 8747DisorderedSequence analysisAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili334 – 354Sequence analysisAdd BLAST21
Coiled coili442 – 462Sequence analysisAdd BLAST21
Coiled coili632 – 656Sequence analysisAdd BLAST25
Coiled coili936 – 956Sequence analysisAdd BLAST21
Coiled coili1321 – 1341Sequence analysisAdd BLAST21
Coiled coili1420 – 1454Sequence analysisAdd BLAST35
Coiled coili1561 – 1581Sequence analysisAdd BLAST21
Coiled coili1634 – 1654Sequence analysisAdd BLAST21
Coiled coili1988 – 2015Sequence analysisAdd BLAST28
Coiled coili2022 – 2042Sequence analysisAdd BLAST21
Coiled coili2245 – 2272Sequence analysisAdd BLAST28
Coiled coili2282 – 2302Sequence analysisAdd BLAST21
Coiled coili2350 – 2377Sequence analysisAdd BLAST28
Coiled coili2490 – 2510Sequence analysisAdd BLAST21
Coiled coili2617 – 2637Sequence analysisAdd BLAST21
Coiled coili3169 – 3189Sequence analysisAdd BLAST21
Coiled coili3413 – 3440Sequence analysisAdd BLAST28
Coiled coili3474 – 3494Sequence analysisAdd BLAST21
Coiled coili3580 – 3600Sequence analysisAdd BLAST21
Coiled coili3698 – 3718Sequence analysisAdd BLAST21
Coiled coili3791 – 3811Sequence analysisAdd BLAST21
Coiled coili3974 – 3994Sequence analysisAdd BLAST21
Coiled coili4116 – 4136Sequence analysisAdd BLAST21
Coiled coili4154 – 4174Sequence analysisAdd BLAST21
Coiled coili4286 – 4313Sequence analysisAdd BLAST28
Coiled coili4351 – 4371Sequence analysisAdd BLAST21
Coiled coili4724 – 4751Sequence analysisAdd BLAST28
Coiled coili4781 – 4815Sequence analysisAdd BLAST35
Coiled coili4859 – 4879Sequence analysisAdd BLAST21
Coiled coili5076 – 5096Sequence analysisAdd BLAST21
Coiled coili5114 – 5134Sequence analysisAdd BLAST21
Coiled coili5365 – 5392Sequence analysisAdd BLAST28
Coiled coili5447 – 5467Sequence analysisAdd BLAST21
Coiled coili5514 – 5541Sequence analysisAdd BLAST28
Coiled coili5608 – 5628Sequence analysisAdd BLAST21
Coiled coili5636 – 5663Sequence analysisAdd BLAST28
Coiled coili5742 – 5769Sequence analysisAdd BLAST28
Coiled coili5780 – 5817Sequence analysisAdd BLAST38
Coiled coili6078 – 6098Sequence analysisAdd BLAST21
Coiled coili6241 – 6268Sequence analysisAdd BLAST28
Coiled coili6533 – 6567Sequence analysisAdd BLAST35
Coiled coili6598 – 6622Sequence analysisAdd BLAST25
Coiled coili7071 – 7098Sequence analysisAdd BLAST28
Coiled coili7177 – 7207Sequence analysisAdd BLAST31
Coiled coili7826 – 7853Sequence analysisAdd BLAST28
Coiled coili8394 – 8414Sequence analysisAdd BLAST21
Coiled coili8482 – 8502Sequence analysisAdd BLAST21
Coiled coili8656 – 8680Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi5871 – 5895Polar residuesSequence analysisAdd BLAST25
Compositional biasi8258 – 8281Polar residuesSequence analysisAdd BLAST24
Compositional biasi8685 – 8738Polar residuesSequence analysisAdd BLAST54

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nesprin family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, RepeatARBA annotation, Transmembrane, Transmembrane helixARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR012315, KASH
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 2 hits
PF10541, KASH, 1 hit
PF00435, Spectrin, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 2 hits
SM01249, KASH, 1 hit
SM00150, SPEC, 43 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits
PS51049, KASH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 18 potential isoforms that are computationally mapped.Show allAlign All

A0A6J1Z7Y1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASRTASRS PRDIANVMQR LQDEQEIVQK RTFTKWINSH LTKRKPPLVV
60 70 80 90 100
DDLFEDMKDG VKLLALLEVL SGQKLPCEQG RRMKRIHAVA NIGTALKFLE
110 120 130 140 150
GRKSMYRGSP IKLVNINSTD IADGRPSIIL GLMWTIILYF QIEELTSNLP
160 170 180 190 200
QLQSLPGSTS SVDSMVSAET ASPPSKRKVA TKIQGNAKKA LLKWVQYTVA
210 220 230 240 250
KQTGIDVKDF GRSWRSGVAF HSVIHAIRPE LVDLEKVKGR SNRENLEEAF
260 270 280 290 300
TIAESELGIP RLLDPEDVDV DKPDEKSIMT YVAQFLKHYP DIHNTGTDGQ
310 320 330 340 350
ENDEILPGFP SFANSIQNFK REDGLILKET KVWIEQFERD LTRAQMTESN
360 370 380 390 400
LQDKYQSFKH FRVQYEIKRK QIEHLIQPVH RDGKLSLDQA LVKQSWDRVS
410 420 430 440 450
SRLFDWHIQL DKSLPAPLGT IGAWLYRAEV ALREEITIQQ VHEETANTIQ
460 470 480 490 500
RKREQHKDLL QNTDAHKRAF HEIYRTRSVN GIPVPPDQLE DMAERFHFVS
510 520 530 540 550
STSELHLMKM EFLELKYRLL SLLVLAESKL KSWIIKYGRR ESVELLLQNY
560 570 580 590 600
ISFIENSKFF EQYEVTYQIL KQTAEMYVKA DGSVEEAENV MKFMNETTAQ
610 620 630 640 650
WRNLSVEVRS VRSMLEEVIA NWDRYGNTVA SLQAWLEDAE KMLNQSEHAK
660 670 680 690 700
KDFFRNLPHW IQQHAAMNDA GNFLIETCDE MVSRDLKQQL LLLNGRWREL
710 720 730 740 750
FMEVKQYARA DEMDRMKKEY ADCITVLSDF ATEAHKKLSE PLEVSFINVK
760 770 780 790 800
LLIQDLEDIE QRVPVMDAQY KMITKTAHLI TKESSQEEAN EMFATMSGLK
810 820 830 840 850
ERLTKVKECC PPLLYESQQL LIPLEELEKQ MTFFYDSLAK IHEIMAVLER
860 870 880 890 900
EAQSSALFKQ KHQELSACQE SCKKTMTQIE KGSQNVQKFV TLSSVLKHFD
910 920 930 940 950
QTKLHRQIAD AHGAFQNMVK KIGDWKKHVE TNSRLMKKFE ESRAELEKVL
960 970 980 990 1000
RIAQEGLEEK GNPEDLLKKH TEFFSQLDQR VLNAFLKACD ELTDILPEQE
1010 1020 1030 1040 1050
QQGLQEAVRK LHKQWKDLQG EAPYHLLHLK IDVEKNRFLA SVEECRTELD
1060 1070 1080 1090 1100
RETTLVPQEG SEKIIKEHRI FFSDKGPHHL CEKRLQLIEE LCLKLPVRDP
1110 1120 1130 1140 1150
VRNTPETCHV TLKELRAAID ATYKKLVEDR DKWKDYARRI SEFSSWISAK
1160 1170 1180 1190 1200
ETQLKGFKNE PIDTANHGEI KHAVEEIRNG VTTKGETLNW LKSRLKILIE
1210 1220 1230 1240 1250
VSSENEAQKQ GDELAKLSSS FKALIALLSE VEKMLSNFGD CVQYKEIVKS
1260 1270 1280 1290 1300
SLGELISDSK EVQEQAEKIL DTENLFEAQQ LLLHHQQKTK RISAKKRDVQ
1310 1320 1330 1340 1350
QQIAQAQQGE GGMPGQVRDE LRKLESTLHS MEHSREKQER RIQVTLRKWE
1360 1370 1380 1390 1400
RFETNKETVV RYLFQTGSSH ERFLSFSSLE SLSSELEQTK EFSKLTGGIA
1410 1420 1430 1440 1450
VQAENLVKEA SEIPLGPKNK QLLQQQAKTI KEQVKKLEDT LEEDIKTMEM
1460 1470 1480 1490 1500
VKNKWDHFGN NFETLSVWIT EKEKELNALE TSSSAMDMQI NQIKVIIQEI
1510 1520 1530 1540 1550
ESKIGCITEL EEAAQSFAQF VTTGESARIK AKLTQIRRYW EELREHAQCL
1560 1570 1580 1590 1600
EGTILGHLSQ QQKFEENLRK IQKSVSEFED KLADPIKICS SATETYKILQ
1610 1620 1630 1640 1650
EHMDLCQALE ALNSAVTTVS ASAQKVANRG TSSVQEAAAL QQRYEETRSR
1660 1670 1680 1690 1700
AKKRQAVLEN LLAHWQRLEK ELSTFLTWLE RCEAIASSPE MDISADRVKV
1710 1720 1730 1740 1750
ESELQSIQAL QNELVSQASV YSNLLQLKES LFSVASKDDV KMMKLHLEQL
1760 1770 1780 1790 1800
NERWRDLPQI ISKRINFLQS VVSEHQQFDE LLLSFSVWIK LFLSELQTTS
1810 1820 1830 1840 1850
EISITDHQAA FARHKDHEAE AESKMGDLQR LRDHLAKLGA LGRAEDLHLL
1860 1870 1880 1890 1900
QGKAEDCFQL FEEASQVVGR RQLALSQLAE FLQHHASLSG VLHRLRHTVE
1910 1920 1930 1940 1950
TTDSMNKKQT DLLKKDLNRA IQDAKTLEST AVSLDGILAK AQYHLKSGSS
1960 1970 1980 1990 2000
EQRTSCRSTA DHLCFELERI QNLLGTKQSE ADALAALKKA FQDQKEELLK
2010 2020 2030 2040 2050
SIEDIEERTD KERLKEPTRQ ALQQRLRVFN QLEDELNSHE HELCWLKDKA
2060 2070 2080 2090 2100
KQIAQKDVAF ASEVDREINR LEVTWDDTKK LIHENQGQCC GLIDLMRDYQ
2110 2120 2130 2140 2150
NLKSVVSKVL ENANNVLATR TTIKDQEDLK WALSKHESVK NEMCNKQKEL
2160 2170 2180 2190 2200
DNFTSKGKQL LSELKKIHSS DFNLVKTDME STVDRWLDVS EKIEENMDRL
2210 2220 2230 2240 2250
RASLTLWGDV LSSKDEIDGW SNNSVPQLAE SISNLNNSVR AEEFLKEFES
2260 2270 2280 2290 2300
EVKNKALRLE ELHCKVNDLK ELTKNPETPP DLQFIEADLR QKLEHAKEIT
2310 2320 2330 2340 2350
EEAKGTLKEF TTQSTQVEKF INDITSWLTK VEEALMNCAQ TETWEGLKKV
2360 2370 2380 2390 2400
KEIQKELQSQ QSNISSTQEN LNSLCRKYHS IELESLGSAM TGLIKNHEAV
2410 2420 2430 2440 2450
SQLCSKTQAS LQDFLEKHFN ESMQEFQEWF SGIKAAAKKS SDRTGDSKVL
2460 2470 2480 2490 2500
EAKLHDLQNI LDSISDGQSK LDAVTQEGQI LYAHLSKQIV SSIQEQITKA
2510 2520 2530 2540 2550
NEEFQAFLKQ CLKDKQALQD CALELGSFED QHRKLNLWIH EMDERLSTEN
2560 2570 2580 2590 2600
FGESKQHIPE KKNEVHKVEM FLGELLAVRE SLDKLSQRGQ LLSEEGHGAG
2610 2620 2630 2640 2650
KEGRLCSQLL TNYQNLLRTT KEKLRNCQLA LQEHEALEEA VQSMWSWVKD
2660 2670 2680 2690 2700
IQDRLACAES TVGSKDTLEK RLLQIQDILL MKGEGEVKLN MAIGKGEQAL
2710 2720 2730 2740 2750
RSSNKQGQKV IQTQLQNLKD VWADIMSSSV RAQSTLESVI SKWNDYLEWK
2760 2770 2780 2790 2800
NQLEQWMEFV DQKVEHPLQP QPGLKEKFSL LDHFQSIVSE AEDHAGTLHR
2810 2820 2830 2840 2850
LASKSRELYQ KTEDESFKET AQEELKTQFN DIITVSKEKM RKVEEIVKDH
2860 2870 2880 2890 2900
LMYLDAVQEF TDWLHSAKEE LHRWSDMSGD SSATQKKLSK IKELMDSRGI
2910 2920 2930 2940 2950
GASRLSRVES LAPAVRQNTS ASGCELVDAE MQALRADWKQ WEDSVLQTRT
2960 2970 2980 2990 3000
SLENLVSQMA LSEQEFSGQV VQLEQALEQF GALLTTCAQQ LALLESKNTD
3010 3020 3030 3040 3050
KEIVECWRKG QEILDALQKA EPKTEDLKSQ LNELCRFSRD LSTYSGKVSG
3060 3070 3080 3090 3100
LIKEYNCLCL QASKGCQTRE QILQQRFQRA FKDFQQWLVN AKITTAKCFD
3110 3120 3130 3140 3150
IPQNISEVST SLQKIQEFLS ESENGQHKLN VMVSKGELLS TLLPKEKADG
3160 3170 3180 3190 3200
IQAKVATAKE DWKKFHSNLH QKESALENLK IQMKDFEVSA EPVQDWLSKT
3210 3220 3230 3240 3250
EKLVQESSNR LYDLPAKRRE QQKLQSVLEE INCYEPQLNR LREKAQQLWE
3260 3270 3280 3290 3300
GQAASKSFMH RVSQLSSQYL ALSNLTKEKV SRLDRIVAEH NQYSLGIKEL
3310 3320 3330 3340 3350
QDWMTDAVHM LDSYCHPISD KSVLDSRMLK LEALLSVKQE KEIQMKMIVT
3360 3370 3380 3390 3400
RGESVLQNTS PEGWPAIQQQ LQSVKDMWAS LLSAAIRCKS QLEGALSKWT
3410 3420 3430 3440 3450
SYQDDVRQFS SWMDSVEASL NESERQYAEL REKTASLGKA KLLSEEVLSY
3460 3470 3480 3490 3500
SSLLEAIELK GAGMTEHYVT QLEFQDLQER YRAITERAKE AVTKSEKLVR
3510 3520 3530 3540 3550
LHQEYQRDLK AFEVWLGQEQ EKLDRYSVLE GDAHTHETTL QDLQELQVHC
3560 3570 3580 3590 3600
AEGQVLLNSV LHTREEVIPS GIPQTEDRAL ESLRQDWQAY QQRLSETRTQ
3610 3620 3630 3640 3650
FNNVVNKLRL MEQKYQQVDE WLKTLEDKVS LRTGRQSNRA AKEIQLHQMK
3660 3670 3680 3690 3700
KWHEEVIAYK DEVEDVGARA QEMLDENHVS SSMGCQATQL TSRYQALLLQ
3710 3720 3730 3740 3750
VLEQIQFLEE EIQSLEESEL SLSSYSDWYS STHKNFKNVA TKIDRVDKAT
3760 3770 3780 3790 3800
MGKKMKTLEG LLKDMDKGHS LLKSAREKGE RALKYLEDGE AEMLRKDIHE
3810 3820 3830 3840 3850
HVEQLKELTS TVRKEHMTLE KGLLLAKEFS DKYKALTQWI SEYQEILHTP
3860 3870 3880 3890 3900
EEPKMELYEK KAQLSKYKSL QQMVLSHEPS IKSVREKGEA LLELVQDVTL
3910 3920 3930 3940 3950
KDKMDKLQSD YQDLCGAGKE HVCSLETKVK DHEDYNSELQ EVEKWLLQMS
3960 3970 3980 3990 4000
GRLVAPDLME TSSLEIITQQ LAHHKAMMEE IAGFEDRLNN LKSKGDNLIS
4010 4020 4030 4040 4050
QCADHLQAKL KQNVYAHLQG TKDSYSAVCS TAQRVYQSLE HELQKHVSRQ
4060 4070 4080 4090 4100
DTLQQCQAWL SAVQPDLKPT QHPPLSRAEA VKQVKHYRAL QEQARTYLDL
4110 4120 4130 4140 4150
LCSTCDLSSS SVKTTAKDIQ ETEQMIEQRL VQAQNLTQGW GEIKHMKAEL
4160 4170 4180 4190 4200
WIYLQDADQQ LQNMKKRHSE LELNIAQNMV SQVKDFVKKL QCKQASVTAI
4210 4220 4230 4240 4250
TERVNKLTKK QESPEHKEIS HLNDQWLDLC LQANSLCLQR EEDLQRTRDY
4260 4270 4280 4290 4300
HDRMSVVEEF LEKFTTEWDN LARSDAESTA VHLGALKKLA LALQERKQAV
4310 4320 4330 4340 4350
EDLKDQKQKM IEHLNLDDKE LVKEQTSHLE QRWFQLEDLV KRKLQVSVTN
4360 4370 4380 4390 4400
LEELNVVRSR FQELMEWAEE QQPNIAEALK QSPPPDMAQN LLMDHLAICS
4410 4420 4430 4440 4450
ELETKQMLLK SLIKDADRVM ADLGLNERQI IQKALSDAQR HVNCLSDLVG
4460 4470 4480 4490 4500
QRRKYLNKAL SEKTQFLMAV FQATSQIQQH ERKIMFREHI CLLPDDVSKQ
4510 4520 4530 4540 4550
VKTCKSAQAS LKTYQNEVTG LWAQGRELMK GATEQEKSEV LGKLQELQSV
4560 4570 4580 4590 4600
YDTVLQKCSH RLQELEKSLV SRKHFKEDFD KACHWLKQAD IITFPEINLM
4610 4620 4630 4640 4650
NESAELHAQL AKYQHILEQS PEYENLLLTL QRTGQTILPS LNEVDHSYLN
4660 4670 4680 4690 4700
EKLNALPLQF NVIVALAKDK FYKVQETILA RKEYASLIEL TTQSLSELED
4710 4720 4730 4740 4750
QFLKMSKVPT DLRVEEAVSL QEGCRALLGE VARLGEAVDE LNQKKESFRS
4760 4770 4780 4790 4800
TGQPWQPDKM LHLVTLYHRL KRQTEQRVGL LEDTSSAYQE HEKMCHQLEK
4810 4820 4830 4840 4850
QLQAVKTEQS KVNEETLPAE EKLKIYHSLA GSLQDSGIVL KRVTVHLEDL
4860 4870 4880 4890 4900
VPHLDPSAYE KAKQQIQSWQ EELKVLTSAI GATVTECESR MVQSIDFQTE
4910 4920 4930 4940 4950
LSRSLDWLRS VKAELSGPVC LDLSLQDIQE EIRKTQIHQE EVQSSLRIMN
4960 4970 4980 4990 5000
ALSNKEKEKF TKAKELLSAD FQHTLAELSE LDGDVQEALR TRQAVLTQIY
5010 5020 5030 5040 5050
SQCQRYYQVF QAANDWLEDA HEMLQLAGNG LEVESVEENL KSHVEFFSTE
5060 5070 5080 5090 5100
DQFHSNLEEL QHLVVSLDPL LKPTGKERLA QKMASLEEKS QRIIQDSHAQ
5110 5120 5130 5140 5150
LDLLQRCAHQ WQTYQKAREE VIELMNEAEK KLSEFSLLKA SSSHEAEEKL
5160 5170 5180 5190 5200
SEHKALASVV NSFHEKVVAL EDKTSQLEKT GNDASKAAIS RSMTTVWQRW
5210 5220 5230 5240 5250
TRLRAVAQDQ EKILEDAVDE WTSFNNKVKK ATETTDQLQD KLPGGSAEKA
5260 5270 5280 5290 5300
SKAELLTLLD HHDALVLELE QQQLALGMLR QQALGMLQDG APQPPGEEPP
5310 5320 5330 5340 5350
TVQEITAMQD RCLNMQEKVK NTGKVVKQEL KEREVVETQI NSVKSWVQET
5360 5370 5380 5390 5400
KEYLGNPTIE IDAQLEELQL LLTEATNHRQ SIEKMAEEQK NKYLGLYSIL
5410 5420 5430 5440 5450
PSELSLQLAE VALDLGTIHD QIQDKVREVE QSKAMSQEFS RQIQKIAKDL
5460 5470 5480 5490 5500
TTILSKLRAK TDNLQQAKID QKVLGEELDG CNLKLMELDA AVQKFSEQNG
5510 5520 5530 5540 5550
QLGKPLAKKV GKLMELHQQT IRQAENRLSK LSQAASHLEE YTEMLEFILK
5560 5570 5580 5590 5600
WIEKAKVLVH GKIAWNSANQ LREQYIFHQT MLEESEEIPS NLEAMIEKLQ
5610 5620 5630 5640 5650
CLASIYSTEK MSQQVADLGR ESEELRQTIK IRLQNLQDAA KDMKKFETEL
5660 5670 5680 5690 5700
KNLQVALEQA QTTLTSPEVG RLSLKEQLSH RQHLLSEMES LKPKVHAVQI
5710 5720 5730 5740 5750
CQSALRIPDD VVASLPLCHC ALHLQAEASR LQHTAIQQCN IMQEAVVQYE
5760 5770 5780 5790 5800
QYEQEMQHLQ ELIEGAHREI EDTPTATSNI QELQAQISRH EELAQKIKGY
5810 5820 5830 5840 5850
QEQIASLNSK CKMLTMKAKH ATMLLTVTEV EGLAEGTEDL DRELLPATSA
5860 5870 5880 5890 5900
HPSVVMMTAG RCHTLLSPVT EESGEEGTNS EISSPPACRS PSPVANTDAS
5910 5920 5930 5940 5950
VNQDIAYYQA LSAERLQTDA ARIHPSTLPS PEFYELGLEP SATAKLDDLQ
5960 5970 5980 5990 6000
RSWETLKNVI SEKQRTLYEA LERQQKYQDS LQSISTKMEA IEMKLSESLE
6010 6020 6030 6040 6050
HGRGPESQMA EHQSSPQALM DEILMLQEEI SELQSSLAEE LVSQSPESDP
6060 6070 6080 6090 6100
AEQLALQSTL TVLAERMSTI KMMASGKRQL LEEKLNDQLE EQRQEQALQR
6110 6120 6130 6140 6150
YRCEADELDH WLLSTKATLD TALGTAQEPM DMEAQLVDCQ NMLVEIEQKV
6160 6170 6180 6190 6200
VALSELSVHN DNLLLEGKAH TKEEAEQLAV KLRTLKGSLL ELQRALHDKQ
6210 6220 6230 6240 6250
LLMQQGTAQE KEESHADLTA SQSPGVQEWL AQARTAWAHQ RQSSLQQQKE
6260 6270 6280 6290 6300
LEQELAEQKS LLRSVASRGE EILTQHSAAE TSAGIGEKPD VLSQELGMEG
6310 6320 6330 6340 6350
EKSASEDQMR MKWESLHQEF STKQKLLQNV LEQEQEQVLY SRPNRLLSGV
6360 6370 6380 6390 6400
PLYKGDGQTQ DRSAVTSLLD GLNQAFEEVS SQGGGTKRQN IHLEQKLYDG
6410 6420 6430 6440 6450
VSATSTWLDD VEERLFVATA LLPEETEACL FNQETLAKDI KEMSEEMDKN
6460 6470 6480 6490 6500
KNLFSQAFPE NGDNRDVIED TLGCLLGRLS LLDSVVNQRC HQMKERLQQI
6510 6520 6530 6540 6550
LNFQNDLKVL CTSLADSKYI ILQKLANVFE QPVAEQIEAI QQAEDGLKEL
6560 6570 6580 6590 6600
DAEIIELKKR GDKLQIEQPS MQELSKLQDM YDELMMTIGS WRSSLNQNLA
6610 6620 6630 6640 6650
LKSQYERAMQ DLADLLETGQ EKMAGDQKII VSSKEEIQQL LDKHKEYFQG
6660 6670 6680 6690 6700
LESHMILTET LFRKIINFAV LQETQFYTEL MTQASAVLKR AHKRGVELEY
6710 6720 6730 6740 6750
ILETWSHLDE DHQALSKQLE VVESSIPSVG LVEESEERLI DRITLYQHLK
6760 6770 6780 6790 6800
SSLHEYQPKL YQVLDDGKRL LISISCSDLE SQLNQLGEQW LDNTNKVSKE
6810 6820 6830 6840 6850
LHRLETVLKH WTRYQSESAE LIHWLQSAKD RLEFWTQQSV TVPQELEMVR
6860 6870 6880 6890 6900
DHLNAFLEFS KEVDAKSSLK SSVLSIGNQL LRLKKVDTAS LRSELSHIDS
6910 6920 6930 6940 6950
QWTDLLTNIP TVQEKLHQLQ MDKLPSRHAI SELMTWISLM ENVIQKDEEN
6960 6970 6980 6990 7000
IKNSIGYKAI HEYLQKYKGF KIDINCKQLT VDFVNQSVLQ ISSQDVESKR
7010 7020 7030 7040 7050
SDKTDFAEQL GAMNKSWQIL QGLVTEKIQL LEGLLESWSE YENNVQSLKT
7060 7070 7080 7090 7100
WYETQENKLK QQHRIGDQAS VQSSMKDCQD LEDLIRAKEK EVEKIEQNGL
7110 7120 7130 7140 7150
ALIQNKKEEV SGVVMSTLRE LNQTWANLDH MVGQFKILLK SVFDQWNNHK
7160 7170 7180 7190 7200
EAFDEINSYL MEARYSLSRF RLLTGSLEAV QVQVDNLQNL QDDLEKQEKN
7210 7220 7230 7240 7250
LQNFGSITNQ LLKECHPPVT ETLTTTLKDV NMRWNNLLEE IAKQLCSSKA
7260 7270 7280 7290 7300
LLQLWQRYKD YSKQCASTVQ QQEDGASELL KAATNKDIAD DEAATWIQDC
7310 7320 7330 7340 7350
NDLLKGLGTA KDSLFVLREL GEQLKQQVDA SAASTIQSDQ LSLSQRLCAL
7360 7370 7380 7390 7400
EQALCKQQTM LQAGVLDYET FTKSLEALEA WIVEAEEILQ GQDPGHSSDL
7410 7420 7430 7440 7450
STIQQRMEEL KGQMLKFSSM APDLDRLNEL GYRLPLNDKE IKRMQNLNRH
7460 7470 7480 7490 7500
WSLISSQTTE RFSKLQSFLL QHQTFLEKCE TWMEFLVQTE QKLAVEISGN
7510 7520 7530 7540 7550
YQHLLEQQRA HELFQAEMFS RQQILHSIII DGQRLLEQGQ VDDRDEFNLK
7560 7570 7580 7590 7600
LTLLSNQWQG VIRRAQQRRG IIDSQIRQWR RYREMAEKLR KWLVEVSYLP
7610 7620 7630 7640 7650
VSALGSVPIP LQQARTLFDE VQFKEKVFLR QQGSYILTVE AGKQLLLSAD
7660 7670 7680 7690 7700
SGAEAALQAE LAEIQEKWRS ASVRLEEQKK KLAFLLKDWE KCENGIADSL
7710 7720 7730 7740 7750
EKLRTFKKKL SPPLPDHHEE LHAEQMRCKE LENAAGNWTD DLAQLALLKD
7760 7770 7780 7790 7800
TLCAYISADD ISILNERMEL LQRQWEELCH QLSLRRQQVS ERLNEWAVFS
7810 7820 7830 7840 7850
EKNKELCEWL TQMESKVSQN GDILIEEMIE KLKKDYQEEI AVAQENKIQL
7860 7870 7880 7890 7900
QQMGERLARA SHESKASEIE YKLGKVNDRW QHLLDLMAAR VKKLKETLVA
7910 7920 7930 7940 7950
VQQLDKNMSS LRTWLAHIES ELAKPIVYDS CDSDEIQKKL TEQQELQRDI
7960 7970 7980 7990 8000
EKHSTGVASV LNLCEVLLHD CDACATDAEC DSIQQATRNL DRRWRNICAM
8010 8020 8030 8040 8050
SMERRLRIEE TWRLWQKFLD DYSRFEDWLK ISERTAAFPS SSGVLYTVAK
8060 8070 8080 8090 8100
EELKKFEAFQ RQVHESLTQL ELINKQYRRL ARENRTDSAC SLKQMVHEGN
8110 8120 8130 8140 8150
QRWDNLQKRV TSILRRLKHF IGQREEFETA RDSILVWLTE MDLQLTNIEH
8160 8170 8180 8190 8200
FSECDVQAKI KQLKAFQQEI SLNHNKIEQI ISQGEQLIEK SEPLDAAVIE
8210 8220 8230 8240 8250
EELDELRRYC QEVFGRVERY HKKLIRLPLP DDEHDLSDRE LELDDSAALS
8260 8270 8280 8290 8300
DLHWRDTSAD SVLSPQPSSN PSLSLAQPLR SERSGRDTPA SVDSIPLEWD
8310 8320 8330 8340 8350
HDYDLSRDLE SAVSRTLPSE DEEVGDDKDF YLRGAVGLSG APSALESQIR
8360 8370 8380 8390 8400
QLDKALDESR FQMQQTENII RSKTPTGPEL DSSYRGYMKL LGECSDSIDS
8410 8420 8430 8440 8450
VRRLEHKLKE EEENFPGFVN LNSTETQTAG VIDRWELIQA QALSKELRMK
8460 8470 8480 8490 8500
QNLQKWQQFN SDLNNIWTWL GETEEELERL QHLELSTDIQ AIELQIKKLK
8510 8520 8530 8540 8550
ELQKAVDHRK AIILSINLCS PEFTQTGSEK SQDLQDRLSQ MNGRWDRVCS
8560 8570 8580 8590 8600
LLDEWRGLLQ DALMQCQDFH EMSHGLLLML ENIDRRKNEI VPIDSNQDAE
8610 8620 8630 8640 8650
TLQDHHKQLM QIRHELLESQ LKVASLQDMS CQLLVNAEGT DCLEAKEKVH
8660 8670 8680 8690 8700
VIGNRLKLLL KEVSRHIKEL EKLLDMSSSQ QDLSSWSSAD ELDTSGSVSP
8710 8720 8730 8740 8750
TSGRSTPNRQ RTPRGKCSLS QPGPSVNSPH SRSIKGGCDS SLSEPRPARS
8760 8770 8780 8790 8800
GRAFLLRVLR AALPLQLLLL LLIGLACLVP MSEEDYSCAL SNNFARSFHP
8810
MLRYTNGPPP L
Length:8,811
Mass (Da):1,012,016
Last modified:October 7, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1BD129E71FF1D21B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 18 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6J1Z5Y2A0A6J1Z5Y2_ACIJB
nesprin-1 isoform X1
SYNE1
8,834Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z4K9A0A6J1Z4K9_ACIJB
nesprin-1 isoform X5
SYNE1
8,827Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z4L3A0A6J1Z4L3_ACIJB
nesprin-1 isoform X10
SYNE1
8,799Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z4V3A0A6J1Z4V3_ACIJB
nesprin-1 isoform X4
SYNE1
8,829Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z4V8A0A6J1Z4V8_ACIJB
nesprin-1 isoform X9
SYNE1
8,806Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z5Y7A0A6J1Z5Y7_ACIJB
nesprin-1 isoform X6
SYNE1
8,825Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z5Z1A0A6J1Z5Z1_ACIJB
nesprin-1 isoform X11
SYNE1
8,787Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z6H8A0A6J1Z6H8_ACIJB
nesprin-1 isoform X2
SYNE1
8,833Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z6I5A0A6J1Z6I5_ACIJB
nesprin-1 isoform X7
SYNE1
8,817Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6J1Z6J0A0A6J1Z6J0_ACIJB
nesprin-1 isoform X12
SYNE1
8,785Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_026912410.1, XM_027056609.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_026912410.1, XM_027056609.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

CDDicd00014, CH, 2 hits
Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR012315, KASH
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PfamiView protein in Pfam
PF00307, CH, 2 hits
PF10541, KASH, 1 hit
PF00435, Spectrin, 12 hits
SMARTiView protein in SMART
SM00033, CH, 2 hits
SM01249, KASH, 1 hit
SM00150, SPEC, 43 hits
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits
PS51049, KASH, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6J1Z7Y1_ACIJB
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6J1Z7Y1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 7, 2020
Last sequence update: October 7, 2020
Last modified: January 19, 2022
This is version 6 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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