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UniProtKB - A0A6J1U5Q6 (A0A6J1U5Q6_9SAUR)

Entry version 2 (02 Dec 2020)
Sequence version 1 (07 Oct 2020)
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Protein
Submitted name:

SMC5-SMC6 complex localization factor protein 2 isoform X1

Gene

SLF2

Organism
Notechis scutatus (mainland tiger snake)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
SMC5-SMC6 complex localization factor protein 2 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLF2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNotechis scutatus (mainland tiger snake)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8663 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Lepidosauria › Squamata › Bifurcata › Unidentata › Episquamata › Toxicofera › Serpentes › Colubroidea › Elapidae › Acanthophiinae › Notechis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000504612 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 33DisorderedSequence analysisAdd BLAST33
Regioni76 – 99DisorderedSequence analysisAdd BLAST24
Regioni153 – 266DisorderedSequence analysisAdd BLAST114
Regioni281 – 316DisorderedSequence analysisAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili557 – 577Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 24PolarSequence analysisAdd BLAST24
Compositional biasi182 – 229PolarSequence analysisAdd BLAST48
Compositional biasi230 – 244PolyampholyteSequence analysisAdd BLAST15
Compositional biasi245 – 266PolarSequence analysisAdd BLAST22
Compositional biasi281 – 301PolarSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM178 family.ARBA annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026161, FAM178

The PANTHER Classification System

More...PANTHERi		PTHR16046, PTHR16046, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14816, FAM178, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A6J1U5Q6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTQNCSGSGS RTQLSVSACS PSQHRPSVDR GAADARSKCI TDFFKPTLKK 
        60         70         80         90        100
DRTVLCSPEK GNGRAGHTVS CVGHVKKNAS SSKQHRRKKL PCSPSGRSPI 
       110        120        130        140        150
IDALFRKAKS EKNNSSENSV NHPKPVVRRL FISKALPDGS FILKDPIYSK 
       160        170        180        190        200
NSERNEKYPV QTKTHLMDNS SRQHKAEYED LDSTGSSLNK WPFTSGNNSL 
       210        220        230        240        250
KKQSHATQCQ KTVYSRLPQV SSSSPKSLGT VRKKRQEKGT KDFLRKNSSS 
       260        270        280        290        300
TSLESSSDES SSAQTSKSVF CSGLSSDKTI VTKSQPSPTA YSSATTSFGT 
       310        320        330        340        350
ANHKHPRKRK RVSSKTNVKN VQYVQKLNKH KYGSSQIPHN TNYSKHRISA 
       360        370        380        390        400
HNSQPADTDL SSSNLPISVE KYEAEENENK SYRCIISKNN QIQISDTSKR 
       410        420        430        440        450
KLQTSTPLIY LETRSYNAST VPSEKIAEPL KCSLGESKTT SKTTLEDYTC 
       460        470        480        490        500
DIIPNSSCNL NKSNHETYEL IQKLKSISDS DAEASDCSVN SSEEETLIPL 
       510        520        530        540        550
EKILFQSVRP PAKKSEEAMH EDEIESTISA THNTSLSKAF TERGASYMNH 
       560        570        580        590        600
LEHLLKEKEE LRRVDELENQ LQHVKERVEI NSEPEDQSTD GELFAEHREF 
       610        620        630        640        650
IEKYSFSQDA IPDQHPGENI FQIVNAGKIF NQNNLDLRNF DFHPQNLIEK 
       660        670        680        690        700
YLLRSGITQQ LFVTIEGLLA STYHNCPCPV PILKWMFQMM SIHPDSTVSR 
       710        720        730        740        750
KILDTLMLLT IRNFSDKNDK QKPWIPSLFD ITTVLINMGI SFNVLFPLQH 
       760        770        780        790        800
FQPGYTENDI MSEMHVTVNK QSKRDICINP TTYFLLIESN LCNIAKFLQL 
       810        820        830        840        850
CINVCPEGYT DREIFILLLL LSKLSLETQL KQFPLVDLEC LVIKLLENIR 
       860        870        880        890        900
NWDTEMSQLS LAISCLSNHH HNLLWLVQFV PNWTTRGRQI RRHLSLVIIS 
       910        920        930        940        950
KLLKSHVKIP STHDHQMSLL CKELVKMKPS GLLKRLSETS GHDDGVTGPF 
       960        970        980        990       1000
LSESEHQAYY LTYVLLHLVR EASNFERTSS NKRKWLLRLC SILEKHVKCD 
      1010       1020       1030       1040 
IREDVRLFYR TKVKDLVART YSKWQQMIHS SQLIQGQIHD FWVPDT
Length:1,046
Mass (Da):118,847
Last modified:October 7, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE45645011291EC8B
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_026523204.1, XM_026667419.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_026523204.1, XM_026667419.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR026161, FAM178
PANTHERiPTHR16046, PTHR16046, 2 hits
PfamiView protein in Pfam
PF14816, FAM178, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6J1U5Q6_9SAUR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6J1U5Q6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 7, 2020
Last sequence update: October 7, 2020
Last modified: December 2, 2020
This is version 2 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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