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Entry version 4 (02 Jun 2021)
Sequence version 1 (07 Oct 2020)
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Protein
Submitted name:

nesprin-1

Gene

SYNE1

Organism
Odocoileus virginianus texanus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
nesprin-1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYNE1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOdocoileus virginianus texanusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9880 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaRuminantiaPecoraCervidaeOdocoileinaeOdocoileus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000504613 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 141Calponin-homology (CH)InterPro annotationAdd BLAST115
Domaini185 – 290Calponin-homology (CH)InterPro annotationAdd BLAST106

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni5867 – 5895DisorderedSequence analysisAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili632 – 656Sequence analysisAdd BLAST25
Coiled coili936 – 956Sequence analysisAdd BLAST21
Coiled coili1321 – 1348Sequence analysisAdd BLAST28
Coiled coili1420 – 1454Sequence analysisAdd BLAST35
Coiled coili1561 – 1581Sequence analysisAdd BLAST21
Coiled coili1909 – 1929Sequence analysisAdd BLAST21
Coiled coili1987 – 2014Sequence analysisAdd BLAST28
Coiled coili2021 – 2041Sequence analysisAdd BLAST21
Coiled coili2091 – 2111Sequence analysisAdd BLAST21
Coiled coili2244 – 2271Sequence analysisAdd BLAST28
Coiled coili2281 – 2301Sequence analysisAdd BLAST21
Coiled coili2349 – 2376Sequence analysisAdd BLAST28
Coiled coili2969 – 2989Sequence analysisAdd BLAST21
Coiled coili3168 – 3188Sequence analysisAdd BLAST21
Coiled coili3412 – 3439Sequence analysisAdd BLAST28
Coiled coili3501 – 3521Sequence analysisAdd BLAST21
Coiled coili3579 – 3599Sequence analysisAdd BLAST21
Coiled coili3697 – 3717Sequence analysisAdd BLAST21
Coiled coili3757 – 3777Sequence analysisAdd BLAST21
Coiled coili3790 – 3810Sequence analysisAdd BLAST21
Coiled coili3973 – 3993Sequence analysisAdd BLAST21
Coiled coili4115 – 4135Sequence analysisAdd BLAST21
Coiled coili4153 – 4173Sequence analysisAdd BLAST21
Coiled coili4282 – 4319Sequence analysisAdd BLAST38
Coiled coili4780 – 4814Sequence analysisAdd BLAST35
Coiled coili4858 – 4878Sequence analysisAdd BLAST21
Coiled coili4970 – 4990Sequence analysisAdd BLAST21
Coiled coili5113 – 5133Sequence analysisAdd BLAST21
Coiled coili5159 – 5179Sequence analysisAdd BLAST21
Coiled coili5220 – 5240Sequence analysisAdd BLAST21
Coiled coili5364 – 5391Sequence analysisAdd BLAST28
Coiled coili5513 – 5543Sequence analysisAdd BLAST31
Coiled coili5635 – 5662Sequence analysisAdd BLAST28
Coiled coili5741 – 5768Sequence analysisAdd BLAST28
Coiled coili5779 – 5816Sequence analysisAdd BLAST38

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi5870 – 5886Polar residuesSequence analysisAdd BLAST17

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 2 hits
PF00435, Spectrin, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 2 hits
SM00150, SPEC, 26 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A6J0WMM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAASRAASRA PRDIANVMQR LQDEQEIVQK RTFTKWINSH LAKRKPPMVV
60 70 80 90 100
DDLFEDMKDG VKLLALLEVL SGQKLPCEQG RRMKRIHAVA NIGTALKFLE
110 120 130 140 150
GRKSMYRGSP IKLVNINSTD IADGRPSIVL GLMWTIILYF QIEELTSNLP
160 170 180 190 200
QLQALSSSTS SVDSMVSSET ASPPSKRKVA TKIQGNAKKA LLKWVQYTVT
210 220 230 240 250
QQSGIEVKDF GRSWRSGVAF HSVIHAIRPE LVDLEKVKGR PNRENLEEAF
260 270 280 290 300
SIAETELGIP RLLDPEDVDV DKPDEKSIMT YVAQFLKQYP DIHSTGSDGQ
310 320 330 340 350
ENDEILPSFP SFTNSIQILK REDRLILKEM KVWIEQFERD LTRTQVTDSS
360 370 380 390 400
LQDKYQSFKH FRVQYEMKRK QIEHLLQPLH RDGKLSLDQA LVKQAWDRVS
410 420 430 440 450
SRLFDWHIQL DKSLPAPLGT IGAWLYRAEV ALREEITVQQ VHEETANTIH
460 470 480 490 500
RKREQHKDLL QNTDAHKRAF HEIYRTRSVN GIPVPPDQLE DMAERFHFVS
510 520 530 540 550
STSELHLMKM EFLELKYRLL SLLVLAESKL KSWIIKYGGR DSVELLLQNY
560 570 580 590 600
ISFIENSKFF EQYEVTYQIL KQTAEMYVKA DGSVEEAENV MKFMNETTAQ
610 620 630 640 650
WRNLSVEVRS VRSMLEEVIA NWDRYGNTVA SLQAWLEDAE KMLNQSEHAK
660 670 680 690 700
KDFFRNLPHW IQQHTAMNDA GNFLIETCDE MVSRDLKQQL LLLNGRWREL
710 720 730 740 750
FMEVKQYARA DELDRMKKEY NDCVTVLSDF ATGAHRKLSE PLEVSFINVK
760 770 780 790 800
LLIQDLEDIE QRMPVMDAQY KMITKTAHLI TKEISQEEAN EMFANMSGLK
810 820 830 840 850
EQLTKVKDCY SPLLSESQQL LVPLEELEKQ MTAFYDSLGK IDEIMTVLEH
860 870 880 890 900
EAQSSPLFKQ KHQELLACQE SCKKAMTQIE KGSQSVQKFV TLSNVLKHFD
910 920 930 940 950
QTKLQRKIAD MHVAFQNMVK KTGDWKKHVE TNSRLMKKFE ESRAELEKVL
960 970 980 990 1000
RVAQEGLEEK GDPEDLLKRH TEFFSQLDQR VLNAFLKACD ELTDILPEQE
1010 1020 1030 1040 1050
QQGLQEAVRK LHKQWKDLQA EAPYHLLHLK IEVEKNRFLA SVEECRAELD
1060 1070 1080 1090 1100
RETKLVPQEG SEKVIKEHRI FFSDKGPHHL CEKRLQLIEE LCLKLPVRDT
1110 1120 1130 1140 1150
VRNTPETCHV TLKELRAAID CTYAKLVGDP DKWRDYTSRI SEFSSWISAK
1160 1170 1180 1190 1200
ETQLKGIKNE TIDTANQGEV KCAVEEIRSG ITKKGETLSW LKSRLKILIE
1210 1220 1230 1240 1250
VSPEDEAQKQ GDELAKLSSS FKALGTLLSE VEKMLSNFGD CVQYKEIVKS
1260 1270 1280 1290 1300
SLEELITGSK EVQEEAEKIL DTENLFEAQQ LLLHHQQKTK RINAKKKDVQ
1310 1320 1330 1340 1350
QQIAQAQQGE GGLPGRVQEE LRKLESTLDN VEHSREKQER RIQVTLRKWE
1360 1370 1380 1390 1400
RFETNKETVV RYLFQTGSSH ERFLSFSSLE SLSSELEQTK EFSKRTEGIA
1410 1420 1430 1440 1450
VQAENLVKEA SEIPLGPKNK QLLQQQAKSI KEQVKKLEDT LEEDIKTMEM
1460 1470 1480 1490 1500
VKNKWDHFGT NFETLSVWIT EKEKELNALE TSSSAMDTQI NQIKVMIKEI
1510 1520 1530 1540 1550
ESKVSSITGL EEEAQSFAQF ITTGESARIK AKLTQIRRYW EELREHAQSL
1560 1570 1580 1590 1600
QGIIVGHLAQ QKKFEENLKK IQQSVSEFED KLADPVKICS SATETYKVLQ
1610 1620 1630 1640 1650
EHMDLCQALE SLTSTVAALS ASARKVSNRD SSIQEAATVQ QSYEGLLGRA
1660 1670 1680 1690 1700
KERQRELEKL LACWQRLEKE LSAFLTWLER CEAIASSPEA DISADRVKLE
1710 1720 1730 1740 1750
SELQSIQVLQ NEVVAQASIY SNLLQLKESL FSVASRDDVK MMKLQLEHLD
1760 1770 1780 1790 1800
ERWRDLPQII SKRINFLQSV VAEHQQFDEL LLSFSVWIKL FLSELQTTSE
1810 1820 1830 1840 1850
ISVMDHQAAL TRHKDHAVEV ESKKGELQSL QGHLAKLGAL GRAEDLHLLQ
1860 1870 1880 1890 1900
GKAEDCLQLF EEASQVVERR QRALCQLAQF LQSHASLSQS LHHLRQTVEA
1910 1920 1930 1940 1950
THSMNKQQSD LLERDLNDAI RNVKTLESAA ISLDGLLTKA QYHLKSGGSE
1960 1970 1980 1990 2000
QRTSCRATAD DLSVELERIQ NLLGTKQSEA DALAVLKKAF RDQKEELLKS
2010 2020 2030 2040 2050
IEDIEERTDK ERLKDLTRQA LQQRLRVFNQ LEDELNSHEH ELCWLKDKAK
2060 2070 2080 2090 2100
QIAQKDVAFA PEVDKEINRL EVTWDDTKKL IHENQGQCCG LIDLIREYQN
2110 2120 2130 2140 2150
LKSAITKVLE NASNVITTRT TVKDQEDLKW ALSKHEAAKN EMCNKQKDLD
2160 2170 2180 2190 2200
NFTSKGKQLL SELKKIHSGD FIMVKTDMES TVDKWLDISE KIEENMDRLR
2210 2220 2230 2240 2250
VSLSIWDDVL SSKNEIDGWS NHYVPQLTES ISNLNDSLRA EEFLKEFESE
2260 2270 2280 2290 2300
VKKKALRLEE LRSKVIDLKE LTKNPETPPD LQFIEADLRQ KLEHAKEITE
2310 2320 2330 2340 2350
EAKGTLKEFT AQSAQVEKFI NDTASWLTKL EESLMNCAQT ETWEGLKKVK
2360 2370 2380 2390 2400
DIQKELQSQQ SNISATQENL NSLCRKYHSV ELGSLGSAMT GLIKRHEAVS
2410 2420 2430 2440 2450
QSCAKTQASL QDSLEKHFNE SMQEFQEWFS GIKAAAKKSS DRTGDSKVLE
2460 2470 2480 2490 2500
AKLHDLQNIL DSVGDGQSKL DAVTREGQTL YAHLSKQIVS SIQEQVTKAN
2510 2520 2530 2540 2550
EEFQAFLKQC LKDKQALQDC ALELGSFEDQ HRKLSLWIHE MEERLSTENL
2560 2570 2580 2590 2600
GESKQHIPEK KNEVHKIEMF LGELLAARES LDKLSQRGQL LSEEGHGAGK
2610 2620 2630 2640 2650
ESRLCSQLLT SYQNLLRMTK EKLRGCQVAL QEHEALEEAL QSMWSWVKDA
2660 2670 2680 2690 2700
QDRLAGAEST VGSKAALERR LLQMQELLLM KGEGEVKLNM AIGKGEQALR
2710 2720 2730 2740 2750
SSNKDGQKVI QTQLQTLKDV WASIMGSSVH AQSTLESVIS QWNDYLEWKN
2760 2770 2780 2790 2800
QLEQWMESVD QKVEHPLQLQ PGLKEKFSLL DHFQSIVSEA EDHVGALQRL
2810 2820 2830 2840 2850
TAKARELYQK TEDETFKDTA QEELKTQFND ILTVSKEKMR KVEEIVKDHL
2860 2870 2880 2890 2900
MYLDAVQEFM DWLHSAKEEL HRWSDMSGDS PATQKKLSKI KELMDSREIG
2910 2920 2930 2940 2950
ARRLSRVESL APAVKQNTTA SGCELLDTEM QALRADWKQW EDSVFQTQTS
2960 2970 2980 2990 3000
LENLVSQMAL SEQEFSGQVA KLEQALEQFS ALLTSWAQQL ALLEGKNTDK
3010 3020 3030 3040 3050
ELVECWQKGR EILDALQKAE PQTENLKSQL NELCQFSRDL STYSGKVSGL
3060 3070 3080 3090 3100
IKEYNCLCLQ ASKGCQNKEQ ILQQRFLRAF KDFQQWLVNA KITTAKCFDI
3110 3120 3130 3140 3150
PQNINEVSTS LQKIQEFLSE SESGQHKLNM MLSKGELLCT LLPKEKASGI
3160 3170 3180 3190 3200
QAKMATAKED WKNFHSNLHQ KESALENLKI QMKDFEVSAE PVQDWLSKTE
3210 3220 3230 3240 3250
KMVHESSNRL YDLPAKRREQ QKLQSVLEEI NCYEPQLHRL KEKAQQLWEG
3260 3270 3280 3290 3300
QAASRSFMHR VSQLSSQYLA LSNVTKEKVS RLDRIVAEHS QFSLGIKDLQ
3310 3320 3330 3340 3350
DWMTDTVHML DSYCHPTSDK SVLDSRVLKL EALLSVKQEK EIQMKMVVTR
3360 3370 3380 3390 3400
GESVLQHASP EGMPAIQLQL ASVKDTWASL WSAAVRCKSQ LEGALSKWTS
3410 3420 3430 3440 3450
YQDDVRQFSS WMDGVEASLN ESERQLAELR EKTAALGKAK LLNEEVLSHG
3460 3470 3480 3490 3500
SLLETIEVKG AGMTEHYVTQ LEFQDLQERY GAIRERTKEA VTKSEKLVRL
3510 3520 3530 3540 3550
HQEYQRDLKA FEAWLEKEQE KLDRYSVLEG DAHTHETALR DLQELQVRCA
3560 3570 3580 3590 3600
EGQALLNSAL HAREEVIPSG IPQTEDRVLE SLRQDWQAYQ QRLSETRTQF
3610 3620 3630 3640 3650
NNVVNKLRLM EQKFQQVDEW LKTTEEKVNL RTGRQSSRAA KEIQLHQMKK
3660 3670 3680 3690 3700
WHEEITAYRD EVEEVGARAQ EILDERHASR RMGCQATQLT SRYQALLLQV
3710 3720 3730 3740 3750
LEQIKFLEEE IQSLEESELS LSSCSDWYNS THKNFKNVAA KIDKVDKAMM
3760 3770 3780 3790 3800
GKKMKALEGL LKDMEKGQSL LKSAREKGER ALKYLEDDEA ETLRKEIHDH
3810 3820 3830 3840 3850
VERLKELTST VRKEHMTLEK GLHLTKEFSD KYKALTQWIA EYRDILHGPE
3860 3870 3880 3890 3900
EPKMELYEKK AQLSKYKSLQ QTVLSHEPSV KSVREKGEAL LELVQDVTLK
3910 3920 3930 3940 3950
DKIDQLQSDY QDLCRAAKEH VCSLEAKVRD HEDYNSELQE VEKWLLQMSG
3960 3970 3980 3990 4000
RLVAPDLMET SSLETVTQQL ARHKAMMEEI AGFEDRLNDL KTKGDNLISQ
4010 4020 4030 4040 4050
CVDHLQAKLK QNIHAHLQGT RDSYSAICST AQRVYQSLEH ELQKHVSRQD
4060 4070 4080 4090 4100
TLQQCQAWLS AVQPDLKPGA NPPLSRAEAV KQVKHFRALQ EQARTYLDLL
4110 4120 4130 4140 4150
CSMCDLSNSS VKTTAKDIQQ TEQMIEQRLA QAQNLTQGWE EIKHMKAELW
4160 4170 4180 4190 4200
IYLQDADQQL QNMKRRHSEL ELNIAQNMVS QVKDFVKKLQ CKQASVNTIT
4210 4220 4230 4240 4250
EKVDELTKKQ ESPEHKEISH LNDQWLDLCL QSNNLCLQRE EDLQRTRDYH
4260 4270 4280 4290 4300
DRMNVVEGFL EKFTTEWDNL ARSDAESTAA HLEALKKLAL ALQERKKAIE
4310 4320 4330 4340 4350
DLKEQKQKMI EHLNLDDKEL VKEQTSHLEQ RWFQLEDLVK RKIQVSITNL
4360 4370 4380 4390 4400
EELSVVRSRF QELMEWAEEQ QPNIAEALKQ SPPPDMAQNL LMDHLAICSE
4410 4420 4430 4440 4450
LEAKQMLLKS LTKDADRVMA DLGLNERQII QKALSDAQRH VSSLSDLVGQ
4460 4470 4480 4490 4500
RRKYLNKALS EKTQFLMAVF QATSQIQQHE RKIMFREHIC LLPDDVSKQV
4510 4520 4530 4540 4550
KTCKSAQASL KTYQNEVTGL WAQGRELMKG VTEQEKSEVL GKLQELQSVY
4560 4570 4580 4590 4600
DSVLQKCSHR LQELEKNLVS RKHFKEDFDK ACHWLKQADI VTFPEINLMN
4610 4620 4630 4640 4650
ETAELHTQMA EYQHILEQSP EYENLLLSLQ RTGQAILPTL NEVDHSYLNE
4660 4670 4680 4690 4700
KLHALPLQFN VIIDLAKDKF YKVQEAMLAR KEYASLIELT SQSLHDLEDQ
4710 4720 4730 4740 4750
FSRMSHIPGH LSVEEALSLQ DGWQALGGEV AGLAKAVDEL NQKKESFRST
4760 4770 4780 4790 4800
GQPWQPDKMP QLITLYHRLK RQTEQRVSFL EDTTSAYQEH ERMCHQLEKQ
4810 4820 4830 4840 4850
LESVRMEQSK VNEETLPAEE KLKVYHSLAG SLQNSGILLK RVTRHLEDLV
4860 4870 4880 4890 4900
SHLDPAAYEK AKHQLQAWQE ELKLLTSAIG ATVTECESRM VQSRDFQTEL
4910 4920 4930 4940 4950
SRSLDWLRSV EAALSGPLCL DPNLRDIQEE IRKVQIHQEE VRSSLRIMNA
4960 4970 4980 4990 5000
LSDKEKEKFT RAKELISADL QRTLAELSEL DGALQEALRT RQTTLTQIYS
5010 5020 5030 5040 5050
QCQRYYQVFQ AANDWLEDAH EMLQLTGNGL DVESAEESLK SHREFFSAED
5060 5070 5080 5090 5100
QFHSNLEELQ SLVANLDPLI KPTGKEDLAQ KMASLKEKSQ MIIQDSHAQL
5110 5120 5130 5140 5150
DLLQRCAAQW QDYQKAREEV IALMNEAEKK LSEFSLLKTS SSHEAEEKLS
5160 5170 5180 5190 5200
EHKALVSVIN SFHEKIVALE GEASELERTG NDASKAAISR STTAVWQRWT
5210 5220 5230 5240 5250
RLRAVAQDQE KLLEDAVDEW TNFNNKVKKA TEMIDQLQDK LPGSSAEKAS
5260 5270 5280 5290 5300
KAELVTFLEY HDTFILELER QQSALGMLRQ QALSMVQDGV TPSPGGETPT
5310 5320 5330 5340 5350
VQEITAMQDR CLNMQEKVKK NGKIVKQELK EREVVETQIS SVKSWVQETK
5360 5370 5380 5390 5400
EYLGNPTIEI DAQLEELKIL LTEATNHRQN VEKMAEEQKN KYLGLSTILP
5410 5420 5430 5440 5450
SELSLQLAEV ALDLGAIHDQ IQDKVKEVEQ SKAMSQEFSQ QIQKIARDLT
5460 5470 5480 5490 5500
TILTKLRAKT DNLVQAKTDQ KVLGEELDDC HLKLMELDNA VQKFSEQNGQ
5510 5520 5530 5540 5550
LGKPLAKKIG KLTELHQQTI RQAENQLSKL NQAASRLEEY NEMLELILRW
5560 5570 5580 5590 5600
IEKTKILIHG KIAWNSASQL REQYISHQTM LEESEDIHND LEAMTEILQY
5610 5620 5630 5640 5650
LDSVYHTETM SQQVADLGRE TEELRQVIKI RLQSLHDAAK DMKKFEAELR
5660 5670 5680 5690 5700
NLQVALEQAQ TTLTSPEVGR LSLKEQLSHR QHLLSEMESL KPKVHAVQVC
5710 5720 5730 5740 5750
QSALRIPEDV VTSLPLCHAA LHLQEEASRL QHTAIQQCNI MQEAVVQYEQ
5760 5770 5780 5790 5800
YEQEMQHLQE LIEGAHREIE DKPVATSNIQ ELQAQISRHE ELAQKIKGYQ
5810 5820 5830 5840 5850
EQIASLNSKC KMLTMKAKHA TMLLTVTEVE GLAEGTEDLD RELLPATSAH
5860 5870 5880 5890 5900
PSVVMMTAGR CHTLLSPVTE ESGEEGTNSE ISSPPACRSP SPVAHTDASV
5910 5920 5930 5940 5950
NQDIAYYQAL SPERLQTDAA KLPPSTLPPQ ELYEPGLEPS ATAKLDDLQR
5960 5970 5980 5990 6000
SWETLKNVIS EKQRTLYEAL ERQQKYQDSL QSISTKMEAI EMKLSESLEQ
6010 6020 6030 6040 6050
SRSRTQARQI QKGLAQVLLY EKGSFQASWV LPHSSRDGFR TSRKRSRLPY
6060 6070 6080 6090 6100
WFCIFKRWFE PSPFSLASSQ KKMAHTLQSH ILMVEIETQK EGGVGDLQMH
6110 6120
VNQAVDGGLH LSGVILMNLG AHG
Length:6,123
Mass (Da):702,423
Last modified:October 7, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i954C4B3047B19CDD
GO

Sequence databases

NCBI Reference Sequences

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RefSeqi
XP_020738076.1, XM_020882417.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_020738076.1, XM_020882417.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

CDDicd00014, CH, 2 hits
Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PfamiView protein in Pfam
PF00307, CH, 2 hits
PF00435, Spectrin, 6 hits
SMARTiView protein in SMART
SM00033, CH, 2 hits
SM00150, SPEC, 26 hits
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A6J0WMM5_ODOVR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A6J0WMM5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 7, 2020
Last sequence update: October 7, 2020
Last modified: June 2, 2021
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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