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UniProtKB - A0A650CNR0 (A0A650CNR0_9CREN)
Protein
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase
Gene
taw3
Organism
Stygiolobus azoricus
Status
Functioni
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72.
UniRule annotationCatalytic activityi
- 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine37 in tRNAPhe + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine37 in tRNAPhe + H+ + S-adenosyl-L-homocysteineUniRule annotationEC:2.1.1.282UniRule annotation
GO - Molecular functioni
- tRNA methyltransferase activity Source: InterPro
GO - Biological processi
- wybutosine biosynthetic process Source: InterPro
Keywordsi
Molecular function | MethyltransferaseUniRule annotationARBA annotation, Transferase |
Biological process | tRNA processingUniRule annotationARBA annotation |
Ligand | S-adenosyl-L-methionineUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferaseUniRule annotation (EC:2.1.1.282UniRule annotation)Alternative name(s): tRNA wyosine derivatives biosynthesis protein Taw3UniRule annotation |
Gene namesi | Name:taw3UniRule annotation ORF Names:D1868_05405Imported |
Organismi | Stygiolobus azoricusImported |
Taxonomic identifieri | 41675 [NCBI] |
Taxonomic lineagei | Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Stygiolobus |
Proteomesi |
|
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 8 – 185 | TYW3InterPro annotationAdd BLAST | 178 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 185 – 213 | DisorderedSequence analysisAdd BLAST | 29 |
Sequence similaritiesi
Belongs to the TYW3 family.UniRule annotation
Family and domain databases
Gene3Di | 3.30.1960.10, 1 hit |
HAMAPi | MF_00266, TYW3_archaea, 1 hit |
InterProi | View protein in InterPro IPR022908, Taw3 IPR003827, tRNA_yW-synthesising IPR036602, tRNA_yW-synthesising-like_sf |
Pfami | View protein in Pfam PF02676, TYW3, 1 hit |
SUPFAMi | SSF111278, SSF111278, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A650CNR0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENWEDYKKK AWERILRDKE IGYLDPDIFE VLEVFFKRQK AYTQSSCSGR
60 70 80 90 100
VSIVDSYLPW ERKDSTVVYK NHITFSMEDL KDTISKGYVR RLWLIVQGPI
110 120 130 140 150
LHVYTKDMEE AWELLKIARG AGFKHSGILT SNNKGVLIEL RTGVKMVHYL
160 170 180 190 200
SPSLDQKELE ELVSISLEVL RKGKDKLRKL KESVESSISN ESMELRENSK
210
RETELHYGIN QPP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP045483 Genomic DNA Translation: QGR19476.1 |
Genome annotation databases
KEGGi | sazo:D1868_05405 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP045483 Genomic DNA Translation: QGR19476.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
KEGGi | sazo:D1868_05405 |
Family and domain databases
Gene3Di | 3.30.1960.10, 1 hit |
HAMAPi | MF_00266, TYW3_archaea, 1 hit |
InterProi | View protein in InterPro IPR022908, Taw3 IPR003827, tRNA_yW-synthesising IPR036602, tRNA_yW-synthesising-like_sf |
Pfami | View protein in Pfam PF02676, TYW3, 1 hit |
SUPFAMi | SSF111278, SSF111278, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A650CNR0_9CREN | |
Accessioni | A0A650CNR0Primary (citable) accession number: A0A650CNR0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 22, 2020 |
Last sequence update: | April 22, 2020 | |
Last modified: | September 29, 2021 | |
This is version 7 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |