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UniProtKB - A0A5S6R6D7 (A0A5S6R6D7_TRIMR)

Entry version 5 (10 Feb 2021)
Sequence version 1 (26 Feb 2020)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Trichuris muris (Mouse whipworm)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTrichuris muris (Mouse whipworm)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri70415 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Nematoda › Enoplea › Dorylaimia › Trichinellida › Trichuridae › Trichuris
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000046395 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini466 – 643Reverse transcriptaseInterPro annotationAdd BLAST178
Domaini975 – 1150Integrase catalyticInterPro annotationAdd BLAST176

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni221 – 246DisorderedSequence analysisAdd BLAST26
Regioni1248 – 1283DisorderedSequence analysisAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili196 – 216Sequence analysisAdd BLAST21
Coiled coili872 – 892Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi221 – 235PolarSequence analysisAdd BLAST15
Compositional biasi1248 – 1262PolarSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.40.70.10, 1 hit
3.30.420.10, 1 hit
3.30.70.270, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR021109, Peptidase_aspartic_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR041577, RT_RNaseH_2

Pfam protein domain database

More...Pfami		View protein in Pfam
PF17921, Integrase_H2C2, 1 hit
PF17919, RT_RNaseH_2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50630, SSF50630, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS50878, RT_POL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A5S6R6D7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDNVSQKLNT SSLSRLTSED TELAANSMVK LPPFWSKDAH LWFARIEAQF 
        60         70         80         90        100
RRSRITSDAA MFDHVVAGLE PDVATEVRDI LIAPPAEQKY ETLKKAIITR 
       110        120        130        140        150
LTDSSSKRLQ QVLHKEELGD RTPSQFWRHL QALADTTVGE SVLRAIWLQR 
       160        170        180        190        200
LPVNVQSILA GQDLGFTMNQ LLAIADRVAE VSQMEVMPVV SQSDPLTQLT 
       210        220        230        240        250
GQIDAISRRL NDLELQQRTM SWSGPKGTNA SSRRTYRCTE RSRRTPSETL 
       260        270        280        290        300
PAAMHVRAAG KRRTQAVDAG AAWGPPKSRR LFVFDRLTRT RFLVDTGAEV 
       310        320        330        340        350
SVHPRVSPHR LSATDIQLSA ANGSKIKSYG KFTLTTDFGL GRTFTWDFMC 
       360        370        380        390        400
ADVTQPIIGA DFLFNFGLIV DLKHGKLVHR ATSASCTGII GSAVTLGIKA 
       410        420        430        440        450
INPTASEFLR LLAEFPSLTR PQMSSGQVNH GITHHILTEG PPKAARPRRL 
       460        470        480        490        500
PADRLRAAKA HFAALLDQGI IRRSSSPWSS ALHLVRKKNG DWRPCGDFRP 
       510        520        530        540        550
LNAVTVPDRY PIPHIEDVSA ALHGKHIFST IDLVRAYYHI PVEPSDIPKT 
       560        570        580        590        600
AITTPFGLFE FVHMPFGLRN AAQTFQRFID TVCKDLPFVF AYIDDILVFS 
       610        620        630        640        650
RNAEEHRCHL RTLFRRLSDY GIRINAAKCV LGKEEVDFLG SRISSAGIMP 
       660        670        680        690        700
SPDKIQTIRD FPRPTDKKAL LKFLGMVNFY RRWIPNAARL EAPIYAIVPK 
       710        720        730        740        750
AGQTFVWSTA AAEAFDTIKT TLVNCTLLTH PNPKSRLALF TDASDIAIGA 
       760        770        780        790        800
VLNQLENGAW RPLAFFSKKL QPTETRYSAY DKELLAIYLA IKRFRHQLEG 
       810        820        830        840        850
RQFTIFSDHK PLSFAFHQKP ESCSPRRLRQ LEFIAQFTTD IRHINGSANT 
       860        870        880        890        900
VADALSRIDE IHIFDPESIA DAQATDDELQ QILQNNTSLQ LEKISLPRTG 
       910        920        930        940        950
KTIWVDTTAG KQRPYVPLAL RRELFDAIHK LSHPGVKATT AMLTARFVWP 
       960        970        980        990       1000
SIRRDCQTWT KLCIECQRYK VVRHTRSAPG TFFMPDRRFA HVHLDIIQLS 
      1010       1020       1030       1040       1050
PSEGYSYCLT MIDRFTRWPE VTPISDISAE TVAKAFYASW ITRFGCPETV 
      1060       1070       1080       1090       1100
TTDRGRQFES VLFQKLLELF GIKRNRTTAF HPQSNGLIER FHRTLKAALK 
      1110       1120       1130       1140       1150
AHRTSKWTDV LPMVLLGLRT APKATTGVSA AELTYGTVLR LPSDFFLQSA 
      1160       1170       1180       1190       1200
KQEDPATYVG CLVRVMRDLR PTPTTRNRSS AQVFVSPNLS SCSHVFLRND 
      1210       1220       1230       1240       1250
AVRRPLDPTY DGPFRVITRH DKTFVLDIAG RQTTVSIDRL IPAHLANETT 
      1260       1270       1280 
QQVTQSDTSI QHEAGPRSRR KVSFSARPDY VYY
Length:1,283
Mass (Da):144,476
Last modified:February 26, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5AF36EA7A50EC021
GO

Genome annotation databases

WormBase ParaSite

More...WBParaSitei		TMUE_3000014964.1; TMUE_3000014964.1; WBGene00302417

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

WBParaSiteiTMUE_3000014964.1; TMUE_3000014964.1; WBGene00302417

Family and domain databases

Gene3Di2.40.70.10, 1 hit
3.30.420.10, 1 hit
3.30.70.270, 2 hits
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR021109, Peptidase_aspartic_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR041577, RT_RNaseH_2
PfamiView protein in Pfam
PF17921, Integrase_H2C2, 1 hit
PF17919, RT_RNaseH_2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit
SUPFAMiSSF50630, SSF50630, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS50878, RT_POL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A5S6R6D7_TRIMR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A5S6R6D7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2020
Last sequence update: February 26, 2020
Last modified: February 10, 2021
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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