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Entry version 5 (10 Feb 2021)
Sequence version 1 (26 Feb 2020)
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Protein

C2H2-type domain-containing protein

Gene
N/A
Organism
Mesocestoides corti
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
C2H2-type domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMesocestoides cortiImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri53468 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaPlatyhelminthesCestodaEucestodaCyclophyllideaMesocestoididaeMesocestoides
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000046399 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini657 – 683C2H2-typeInterPro annotationAdd BLAST27

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni26 – 55DisorderedSequence analysisAdd BLAST30
Regioni232 – 254DisorderedSequence analysisAdd BLAST23
Regioni295 – 323DisorderedSequence analysisAdd BLAST29
Regioni744 – 786DisorderedSequence analysisAdd BLAST43
Regioni1095 – 1164DisorderedSequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi744 – 762PolarSequence analysisAdd BLAST19
Compositional biasi1095 – 1134PolarSequence analysisAdd BLAST40

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013087, Znf_C2H2_type

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A5K3FRJ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLLFSQQLPP IRHPAPLLLG GVVPRDPQPP SLASPPAHAL TAFPLPPSTS
60 70 80 90 100
RQPLLPRQSV SSRLNFNSIF SSPARLLQKV RAKALPELSS VLRLDPSVLL
110 120 130 140 150
WSPDQNGAEK HKSRHPNPKG HHMCLFCRRT FSSASLYSNH LNRPVARVIY
160 170 180 190 200
RCHLCPPQQD TAPTPTVVPA LQPPSLDNAA PPASNLSAPN LCALFVHMTQ
210 220 230 240 250
RHANEPVSAW RLIPSRLSVN AIPWLVGAGD PLEGSACEEE ENQSGGGGSQ
260 270 280 290 300
PPNQQLYVEG QELVDLGNDL DRGITNLLRT QEFCFLPAGT GQSPDTSFLR
310 320 330 340 350
IPDIPSMTAS SSSSSSLSSS SQTCPQLLSQ HGLPLNQSSS ISHLLFRLAE
360 370 380 390 400
GSVWNGQFFL SAWHARVTNS GATAQKNGLG GTPSPPPAAT RDQVEQAYTA
410 420 430 440 450
LLGCGRSNPD FHRVLRCLMC GDFRTNSPTA LRHHLSGVPG SPDTVLARCA
460 470 480 490 500
FCSLSVSHNS GLCSVKAHIL FHLGIFLVCP QCGFTPPPDL PPPLAEICLR
510 520 530 540 550
LHLRFSCFHF NVAKVFVCTR TTCSDKIFLT MENFVHHWFE AHTARKYACQ
560 570 580 590 600
LCSGANLQSK VEDTGDGACA NRLNPRNQLY SYDFRDFAAV CSHLQERHAL
610 620 630 640 650
APASASTYSQ IGYECSECSY ITPVPVTFAG HFSTAHCRPG DSTVVGCPTT
660 670 680 690 700
CEVRSAYNCF GECKRLFFDA NEFRRHLRVC PHAVAVLSRT FGENCLNITP
710 720 730 740 750
QPSEAAASES GTESVSQMTT TTVADSPLCF CLYCGIGLKK PPVRRSSQST
760 770 780 790 800
SPAPQNQAVS LPVRGGSGEE RASERPRGDA KSTVTFPDLG SLHSHEISNH
810 820 830 840 850
VVCVGVSGQI GCPWCGDKVQ LVSSDPLDHA NGLVEHLSMH ARANPYVAWH
860 870 880 890 900
LDRTRRFSER PGDVIVCQCQ SGCLDSPLAL MAHASAFPTA SSCFRGLRKR
910 920 930 940 950
RHDDNNLLPF PSLFADEEAM NNTPDTPTSG TISTVRPLHL PGGHPPLSKA
960 970 980 990 1000
VFEHLRFGDH LNSDPRLRLF DETLNAGSDE NAVAVATAKA FQCPICKSVE
1010 1020 1030 1040 1050
ATRWALTEHA FFSHWLRLCY VCCDYIHTEK PANSSDVANA ASIWDHVFAC
1060 1070 1080 1090 1100
LTQRHKLLTM KNEPDHPAPS SSAQIDDCIC GDSLSGEVSI VEVDLSSSDG
1110 1120 1130 1140 1150
RISPNKGQPK NPTKTTLYPP HPPASSTGGT SKSHHAIPSR HCGDFMGLVR
1160
KEPRLESSAT SYQR
Length:1,164
Mass (Da):126,293
Last modified:February 26, 2020 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB7A4B6E3498C57A6
GO

Genome annotation databases

WormBase ParaSite

More...
WBParaSitei
MCU_009400-RA; MCU_009400-RA; MCU_009400

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

WBParaSiteiMCU_009400-RA; MCU_009400-RA; MCU_009400

Family and domain databases

InterProiView protein in InterPro
IPR013087, Znf_C2H2_type
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 1 hit
PS50157, ZINC_FINGER_C2H2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A5K3FRJ5_9CEST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A5K3FRJ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 26, 2020
Last sequence update: February 26, 2020
Last modified: February 10, 2021
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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