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Entry version 8 (02 Jun 2021)
Sequence version 1 (11 Dec 2019)
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Protein
Submitted name:

AT-hook containing transcription factor 1

Gene

AHCTF1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT-hook containing transcription factor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHCTF1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:96050, AHCTF1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini36 – 525ELYS-bbInterPro annotationAdd BLAST490
Domaini758 – 980ELYSInterPro annotationAdd BLAST223

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1306 – 1341DisorderedSequence analysisAdd BLAST36
Regioni1780 – 1805DisorderedSequence analysisAdd BLAST26
Regioni1827 – 1883DisorderedSequence analysisAdd BLAST57
Regioni1942 – 2120DisorderedSequence analysisAdd BLAST179
Regioni2134 – 2172DisorderedSequence analysisAdd BLAST39
Regioni2217 – 2307DisorderedSequence analysisAdd BLAST91

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1311 – 1325Polar residuesSequence analysisAdd BLAST15
Compositional biasi1780 – 1798Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi1827 – 1851Polar residuesSequence analysisAdd BLAST25
Compositional biasi1942 – 1972Polar residuesSequence analysisAdd BLAST31
Compositional biasi1973 – 2045Basic and acidic residuesSequence analysisAdd BLAST73
Compositional biasi2083 – 2097Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2103 – 2120Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi2217 – 2246Basic and acidic residuesSequence analysisAdd BLAST30
Compositional biasi2274 – 2288Basic and acidic residuesSequence analysisAdd BLAST15

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018900

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032040, ELYS-bb
IPR025151, ELYS_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13934, ELYS, 1 hit
PF16687, ELYS-bb, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A5G2R3A1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VETLAGLPLA EPAGTLSLSY VGVCSTCSRA WLGESMRDLT AQVTSDLLQF
60 70 80 90 100
PEVTIQALGE DEITLESVLR GKFAAGRNGL ACLACGPQLE VVNSLTGERL
110 120 130 140 150
SAYRFSGVNE QPPIVLAVKE FSWQKRTGLL IGLEEFEGSV LCLYDLGLSR
160 170 180 190 200
VVKAVVLPGR VTAIEPIINH GGASASTQHL HPSLRWLFGV AAVVTDVGQI
210 220 230 240 250
LLIDLCLDDL SGSQNEVEAS DLEVITGIPA EVPHIRENVM REGRHLCFQL
260 270 280 290 300
VSPSGIAVST LSYINRTNQL AVGFSDGYLA LWNMKSMKRE YYTQLEGGRV
310 320 330 340 350
PVYAVTFQEP ENDPRNCCYL WAVQSTQDSE GDVLSLHLLQ LAFGDRKCLA
360 370 380 390 400
SGQILYEGLE YCEERYTLDL TGGGMFPVRG QTGNTKLLGC QSIEKFRSHG
410 420 430 440 450
DREEGMNEAL SPDTSVSVFT WQVNIYGQGK PSIYLGLFDI NRWYHAQMPD
460 470 480 490 500
SLRSGEYLHN CSYFALWSLD SVVSKTSPHY VLDVLVHERS LSRGVPPSYP
510 520 530 540 550
PPEQFFNPST YNFDATCLLN SGVVHITCTG FQKETLTFLK KSGPSLNEVI
560 570 580 590 600
PDGYNRCLVA GLLSPRLIDI QPSSLSQEEQ LEAILSAAIQ TSSLGLLTGC
610 620 630 640 650
IRRWITEEQP NSAANLRFVL EWTWNKVVFT KGEFDRLCAP LFDGSCRFID
660 670 680 690 700
PQTIQSIQQC SLLLSNLNTV LSCFATEAQE ITERGVMDLS NKYTVSQLIC
710 720 730 740 750
QYAQVVLWFS HSGLLPEGLD DAVQLSRLCY NYPVIQNYYT SRRQKCERLS
760 770 780 790 800
RGKWNPDCLM IDGMVSQLGD RVEKLWKRDE GGTGKYPPTS LHALLDIYLL
810 820 830 840 850
EDVTEASKHS ITIYLLLDIM YSFPNKTDTS IESFPTAFAI SWGQVKLIQG
860 870 880 890 900
FWLIDHNDYE SGLDLLFHPA TAKPVSWQHS KIIQAFMSQG EPRQALRYIQ
910 920 930 940 950
TMRPTVSTDS DVTLHLTVLL FNRCMVEAWD LVRQHSSRLN IEELLKHTYE
960 970 980 990 1000
VCQEMGLMED LLKLPFTDTE QECLVKFLQS SASIQNHEFL LVHHLQRANY
1010 1020 1030 1040 1050
IPALKLNQTL KINLMNDRDP RLRERSVARN SILDQYGKIL PRVQRKLAIE
1060 1070 1080 1090 1100
RAKPYRLSAS SVLREVSRPK PLSAVPKQAV TGTVFTRSTF INNVLSKIGE
1110 1120 1130 1140 1150
VWASSEPKNS LSVYNSPKIE APSPVVYSLP DLELPEAFVG TPISKASQKI
1160 1170 1180 1190 1200
SRLLDLVVQP VPQPSQCLGF IQHIPPRSPL YLVSSSLSLS SQLKESRQNA
1210 1220 1230 1240 1250
SRASELHLLE TPLVVKKAKT LAMSVTSSGF AEFTPQSILR SGLRTTPLAS
1260 1270 1280 1290 1300
PSLSPGRSLT PPLRLKETRI SFMEEGLTTE WAAGAADDSK TKVFITEPFH
1310 1320 1330 1340 1350
KCGVPAETGW QKNKDKTTSF SMSSPEKDHQ EVDVQSQDTT SQGLEKLDIS
1360 1370 1380 1390 1400
VEHSNASTRS DQTTLEYQDA PLPEDLEDIF MASMPPSSST ELITNLTGQS
1410 1420 1430 1440 1450
EKDSDKDVFE SEVTPPDLEK QMGTLEDAET RDLLVAEGAL SELNHLSPSQ
1460 1470 1480 1490 1500
GVEASCVSSI HEGSILTPES MVPVLDKGLV SIETCTSTIR TGNNKSVADV
1510 1520 1530 1540 1550
LGDNGSSGLL ISESPAISEH RLDQEVALNV KEDHEIEVDV LKARVDLPEE
1560 1570 1580 1590 1600
KPPISDDPPD TQEIHVVEHE KVEVQDSGQE ARNLSFNELY PSGTLKLQYN
1610 1620 1630 1640 1650
FDTIEKQFCD LPDSKDSAEC DIAEVDRELF VAQSNFTLIL EGEEGEIETG
1660 1670 1680 1690 1700
DSAASNVLAK AANAATEEKH TCSRENDSHR HVANLPSVLT SDQESQKVET
1710 1720 1730 1740 1750
LPYVPEPIKV AIAENLLDVI KDTRSKEITS DTMEQSIHDN IPLISQKVMC
1760 1770 1780 1790 1800
STKLAKTPFK TVQETSAVTI NVSQINDMIS SRTRKKRRVQ DMSVKSAHQE
1810 1820 1830 1840 1850
ESADVATPEM LGLSIMKKTR KTKEISGAFE SASSDDKGIS QNQQTPQNSV
1860 1870 1880 1890 1900
TPRRGRRKKE INQDTSEDIN SVEQELEATP GRELRRVKSS QLLESVTEES
1910 1920 1930 1940 1950
SFRKDVKLSS VTKRTPKRIK KSVENQESVE VINDLKVSKI ASPSRSTRKL
1960 1970 1980 1990 2000
RSACLETSES TAGESTEQQL PLQRNRRVRK REGSASDVVE DSKFDSSQRK
2010 2020 2030 2040 2050
PPAEFDTPAT PRKRGRPRKT NPSEDVESKA VKGARSPETR EGLNIQRRST
2060 2070 2080 2090 2100
RNTPAKSGNT EVGKLALETS VFVPSEELAT PVSSKKKPTK RTENQSQKRP
2110 2120 2130 2140 2150
LRSISEKCID EEMTHKEVDD QEEKLLATVA LTKSSRGTRT RSSKAVLLPD
2160 2170 2180 2190 2200
LSEPKNESLF SPPVSKIPRK EKAKKIEAPA QLKELVSDLS SQFVFSPPAL
2210 2220 2230 2240 2250
RTRQKNLTNT SKLIDKLEDD APSVETVEKQ QVKRARTTKT RQASKNTEKE
2260 2270 2280 2290 2300
SWSPPPVEVK LISPLASPVD GVKSRPRRAA EVTGKTLGRS RKKVSSFPKQ

VLRRKML
Length:2,307
Mass (Da):256,215
Last modified:December 11, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB981BC6E49AEC381
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A287A0A3A0A287A0A3_PIG
AT-hook containing transcription fa...
AHCTF1
2,333Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1S8P4F1S8P4_PIG
AT-hook containing transcription fa...
AHCTF1
2,281Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A287A3H9A0A287A3H9_PIG
AT-hook containing transcription fa...
AHCTF1
2,199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK02000071 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000080963; ENSSSCP00000070827; ENSSSCG00000010863

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000071 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSSSCT00000080963; ENSSSCP00000070827; ENSSSCG00000010863

Organism-specific databases

VGNCiVGNC:96050, AHCTF1

Phylogenomic databases

GeneTreeiENSGT00390000018900

Family and domain databases

InterProiView protein in InterPro
IPR032040, ELYS-bb
IPR025151, ELYS_dom
PfamiView protein in Pfam
PF13934, ELYS, 1 hit
PF16687, ELYS-bb, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A5G2R3A1_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A5G2R3A1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 11, 2019
Last sequence update: December 11, 2019
Last modified: June 2, 2021
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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