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Entry version 6 (07 Oct 2020)
Sequence version 1 (13 Nov 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

MONAX_5E042413

Organism
Marmota monax (Woodchuck)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processRNA-mediated gene silencingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:MONAX_5E042413Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMarmota monax (Woodchuck)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9995 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciuromorphaSciuridaeXerinaeMarmotiniMarmota
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000335636 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1062 – 1179Ago_hookInterPro annotationAdd BLAST118
Domaini1251 – 1410M_domainInterPro annotationAdd BLAST160

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 141DisorderedSequence analysisAdd BLAST141
Regioni165 – 213DisorderedSequence analysisAdd BLAST49
Regioni226 – 279DisorderedSequence analysisAdd BLAST54
Regioni548 – 687DisorderedSequence analysisAdd BLAST140
Regioni707 – 740DisorderedSequence analysisAdd BLAST34
Regioni756 – 797DisorderedSequence analysisAdd BLAST42
Regioni812 – 1118DisorderedSequence analysisAdd BLAST307
Regioni1227 – 1298DisorderedSequence analysisAdd BLAST72
Regioni1353 – 1386DisorderedSequence analysisAdd BLAST34
Regioni1506 – 1541DisorderedSequence analysisAdd BLAST36

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 38PolyampholyteSequence analysisAdd BLAST38
Compositional biasi42 – 114PolarSequence analysisAdd BLAST73
Compositional biasi244 – 279PolarSequence analysisAdd BLAST36
Compositional biasi548 – 665PolarSequence analysisAdd BLAST118
Compositional biasi666 – 687PolyampholyteSequence analysisAdd BLAST22
Compositional biasi707 – 726PolarSequence analysisAdd BLAST20
Compositional biasi812 – 904PolarSequence analysisAdd BLAST93
Compositional biasi911 – 939PolarSequence analysisAdd BLAST29
Compositional biasi971 – 993PolyampholyteSequence analysisAdd BLAST23
Compositional biasi1000 – 1046PolarSequence analysisAdd BLAST47
Compositional biasi1083 – 1108PolarSequence analysisAdd BLAST26
Compositional biasi1241 – 1255PolarSequence analysisAdd BLAST15
Compositional biasi1262 – 1294PolarSequence analysisAdd BLAST33

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019486, Argonaute_hook_dom
IPR026805, GW182_M_dom
IPR033501, TNRC6A

The PANTHER Classification System

More...
PANTHERi
PTHR13020:SF28, PTHR13020:SF28, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10427, Ago_hook, 1 hit
PF12938, M_domain, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A5E4B2Y1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRDLVQEEEQ LMEEKKKKKD DKKKKEAAQK KATEQKIKVP EQIKPSVSQP
60 70 80 90 100
QPANSNNGTS TATSTNNNAK RATANNQQQQ QQQQQPQQPQ QQQQQQQPPP
110 120 130 140 150
PLLQQQQQQQ QPPQPQALPR YPREVPPRFR HQEHKQLLKR GQHFPVIAAN
160 170 180 190 200
LGSAVKVLNS QSESSAVINQ QPQNNGEVQN SRTESDINHN TSGSHYENSQ
210 220 230 240 250
RGPVSSTSDS STNCKNAVVS DLLEKEVWPS VPGSDPELAS ECVDADSASS
260 270 280 290 300
SESERNITIM ASGSTGGEKD SLRNSTGLGS QNKFVVGSSS NNVGHGSSTG
310 320 330 340 350
PWGFSHGAII STCQVSVDAP ESKSESSNNR MNAWGTVSSS SNGGLNPSTL
360 370 380 390 400
NSASNHGAWP VLENNGLALK GPVGSGNSGI NIQCSTIGQM PNNQSINSKV
410 420 430 440 450
SGSSTHGTWG NLQETCESEV SGTQKVSFSG QPQNITTEMT GPNNTTNFMT
460 470 480 490 500
SSLPNSGSVQ NNELPSSNTG AWRVSTMNHP QIQAPSVMNG TSLSHLSNGE
510 520 530 540 550
SKSGGSYGTT WGAYGSNYSG DKCSGPNGQA NGDTVNATLM QPGINGPVGT
560 570 580 590 600
NFQVNTNKGG SVWESGAANS QSTSWGSGNG ANSGGSRRGW GTPAQNTGTN
610 620 630 640 650
IPSVEWNKLP SNQHSSDSAN GNGKKFTNGW KSTEEEDQGS ATSQTNEQSS
660 670 680 690 700
VWAKTGGAVE SEGSTESTGR LEEKATGDSQ SRDRRKLDQH TLLQSIVNRT
710 720 730 740 750
DLDPRVLSNS GWGQTPIKQN TAWDTETSPR GERKTDNGTE AWGSSAAQTL
760 770 780 790 800
NSGACMEKTG PNGNDTSAVS GWGDPKPALR WGDSKGSNCQ GGWEDDSAAT
810 820 830 840 850
GMIKSNQWGN CKEEKSAWND SQKNKQGWGD GQKASQGWSV SASDNWGETS
860 870 880 890 900
RSNHWGEANK KSSSGGSDSD RSVSGWNELG KTSSFTWGNN INPNNSSGWD
910 920 930 940 950
ESAKPNPSQG WGDPPKSNQS LGWGDSSKPV SSPDWNKQQD LVGSWGIPPA
960 970 980 990 1000
TGKPPGTGWL GGPIPAPAKE EEPTGWEEPS PESIRRKMEI DDGTSAWGDP
1010 1020 1030 1040 1050
SKYNYKNVNM WNKNVPNGSS RSDQQAQVHQ LLPSASAISS KEASSGSGWG
1060 1070 1080 1090 1100
EPWGEPSTPA TTVDNGTSAW GKPIDSGPSW GEPIAPASNT STWGSSSVGP
1110 1120 1130 1140 1150
QALSKSGPKS MQDGWCGDDM PLPGNRPTGW EEEEDVEIGM WNSNSSQELN
1160 1170 1180 1190 1200
SSLNWPPYTK KMSSKGMMKG GNKQEEAWIN PFVKQFSNIS FSRDSPEENV
1210 1220 1230 1240 1250
QSNKMDLSGG MLQDKRMEID KHSLNIGDYN RTVGKGPGSR PQISKESSME
1260 1270 1280 1290 1300
RNPYFDKNGN PSMFGVGNTA AQPRGLQQPP AQPLSSSQPN LRAQVPPPLL
1310 1320 1330 1340 1350
SPQVPVSLLK YAPNNGGLNP LFGPQQVAML NQLSQLNQLS QISQLQRLLA
1360 1370 1380 1390 1400
QQQRAQSQRS VPSGNRQQQD QQGRPLSVQQ QMMQQSRQLD PNVLVKQPTP
1410 1420 1430 1440 1450
PSQQQSLHQP AMKSFLDNVM PHTTPELQKG PSPINAFSNF PIGLNSNLNV
1460 1470 1480 1490 1500
NMDMNSIKEP QSRLRKWTTV DSISVNTSLD QNSSKHGAIS SGFRLEESPF
1510 1520 1530 1540 1550
VPYDFMNSSS SPASPPGSVG DGWPRAKSPN GSSSVNWPPG KVRTARSVRQ
1560 1570 1580 1590 1600
CSCWGFLACR LPSGLARCML GPSLPSDEER GDDGRKGGRR VSESVCVVPT

LCFH
Length:1,604
Mass (Da):171,905
Last modified:November 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4CCA6933F860999
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5E4B389A0A5E4B389_MARMO
Uncharacterized protein
MONAX_5E042413
1,643Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5E4B1A1A0A5E4B1A1_MARMO
Uncharacterized protein
MONAX_5E042413
1,508Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5E4B438A0A5E4B438_MARMO
Uncharacterized protein
MONAX_5E042413
1,767Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5E4B4B1A0A5E4B4B1_MARMO
Uncharacterized protein
MONAX_5E042413
1,519Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5E4B1G0A0A5E4B1G0_MARMO
Uncharacterized protein
MONAX_5E042413
1,393Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5E4B287A0A5E4B287_MARMO
Uncharacterized protein
MONAX_5E042413
1,358Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CABDUW010000230 Genomic DNA Translation: VTJ63510.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABDUW010000230 Genomic DNA Translation: VTJ63510.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR019486, Argonaute_hook_dom
IPR026805, GW182_M_dom
IPR033501, TNRC6A
PANTHERiPTHR13020:SF28, PTHR13020:SF28, 2 hits
PfamiView protein in Pfam
PF10427, Ago_hook, 1 hit
PF12938, M_domain, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A5E4B2Y1_MARMO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A5E4B2Y1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2019
Last sequence update: November 13, 2019
Last modified: October 7, 2020
This is version 6 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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