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UniProtKB - A0A5E4ARK6 (A0A5E4ARK6_MARMO)

Entry version 5 (12 Aug 2020)
Sequence version 1 (13 Nov 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

MONAX_5E001983

Organism
Marmota monax (Woodchuck)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:MONAX_5E001983Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMarmota monax (Woodchuck)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9995 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciuromorpha › Sciuridae › Xerinae › Marmotini › Marmota
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000335636 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei197 – 217HelicalSequence analysisAdd BLAST21
Transmembranei229 – 246HelicalSequence analysisAdd BLAST18
Transmembranei416 – 438HelicalSequence analysisAdd BLAST23
Transmembranei458 – 480HelicalSequence analysisAdd BLAST23
Transmembranei1230 – 1255HelicalSequence analysisAdd BLAST26
Transmembranei1261 – 1278HelicalSequence analysisAdd BLAST18
Transmembranei1304 – 1328HelicalSequence analysisAdd BLAST25
Transmembranei1372 – 1389HelicalSequence analysisAdd BLAST18
Transmembranei1401 – 1423HelicalSequence analysisAdd BLAST23
Transmembranei1443 – 1464HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 44DisorderedSequence analysisAdd BLAST44
Regioni620 – 676DisorderedSequence analysisAdd BLAST57

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili254 – 274Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi14 – 28PolarSequence analysisAdd BLAST15
Compositional biasi662 – 676PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR023298, ATPase_P-typ_TM_dom_sf
IPR039720, TMEM94

The PANTHER Classification System

More...PANTHERi		PTHR13219, PTHR13219, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF81665, SSF81665, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A5E4ARK6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLLGDEEER PKTQSIGQFS SQTVGKPPRV ASNGHGCDPW RRGREVRRGL 
        60         70         80         90        100
GGERGLDADE EDGPSGPALL WVSSSVLLIG SSYRSLLQAP DLTALVSRCC 
       110        120        130        140        150
DWGRRAGVCP CWGGVFLPGV TAFIWACLQY PGPMDLKEKH LGEPPVALGL 
       160        170        180        190        200
STWKALSVLK EQLEAVLEGH LKEQKKYLTW KEAWRNSFLH HSNRCSCFHW 
       210        220        230        240        250
PGASLMLLAV LLLLGCYGGQ PAGSHGVELV NASALFLLLL LNLVLIGRQD 
       260        270        280        290        300
RLKRREVERR LRGIIDQIQD ALRDSKEIKW PNALYPDLHM PFAPSWSLHW 
       310        320        330        340        350
AYRDGHLVNL PVSLLVEGDI IALRPGQESF ASLRGIKDDE HIVLEPGDLF 
       360        370        380        390        400
PPFSPPPSPR GEVKKGPQNP QQHRLFRVLE TPVIDNIRWC LDMALSRPVT 
       410        420        430        440        450
ALDNERFTVQ SAMLHYAVPV VLAGFLITNA LRCMFSAPGV TSWQYTLLQL 
       460        470        480        490        500
QVNGMLPILP LLFPVLWVLA TACGEARVLA QMSKASPSSL LAKFSEDTLS 
       510        520        530        540        550
SYTEAVSSQE MLRCIWGHFL RVIQGTSPTL SHSASLLHSL GSVTVLCCVD 
       560        570        580        590        600
KQGILSWPNP SPETVLFFSG KVEPPHSSHE DLTDDLSTRS FCHPEVEEEP 
       610        620        630        640        650
HERDALLTGS LSNTLHLSNE QERGDWPGDG PKPPEAYSYH KAHGRNKHPS 
       660        670        680        690        700
GSNVSFSRDT EGGEEGPGKG HPGTEAEPYE AEDFVCDYHL EMLSLSQDQQ 
       710        720        730        740        750
NPSCIQFDDS NWQLHLTSLK PLGLNVLLNL CNASVTERLC RFSDHLCHVA 
       760        770        780        790        800
LQESHRTVLP VHVPWGLCEL ARLIGFTPGA KELFKQENHL ALYRLPSAET 
       810        820        830        840        850
VKETLLGRPS CVTKRRPPLS HMISLFIKDT ATSTEQMLSH GTADVVLEAC 
       860        870        880        890        900
TDFWDGADIY PLSGSDRKKV LDFYQRACLS GYCSAFAYKP MNCALSSQLN 
       910        920        930        940        950
GKCIELVQVP GQSSIFTMCE LPSTIPLKQN TRRNSWSSDE GIGEVLEKED 
       960        970        980        990       1000
CMQALSGQIF MGMVSSQYQA RLDIVRLIDG LVNACIRFVY FSLEDELKSK 
      1010       1020       1030       1040       1050
VFAEKMGLET GWNCHISLTP NGDMPGSEIP PSSPSHAGSL HDDLNQVSRD 
      1060       1070       1080       1090       1100
DVEGLLLMEE EGHSDLISFQ PTDSDIPSFL EDCNRAKLPR GIHQVRPHLQ 
      1110       1120       1130       1140       1150
NIDNVPLLVP LFTDCTPETM CEMIKIMQEY GEVTCCLGSS ANLRNSCLFL 
      1160       1170       1180       1190       1200
QSDVSIALDP LYPSRCSWET FGYATSTSMA QASDGLSPLQ LSGQLNSLPC 
      1210       1220       1230       1240       1250
SLTFRQEETI SIIRLIEQAR HATYGIRKCF LFLLQCQLTL VVIQFLSCLV 
      1260       1270       1280       1290       1300
QLPPLLSTTD ILWLSCFCYP LLSISLLGKP PHSSIMSMAT GKNLQSIPKK 
      1310       1320       1330       1340       1350
TQHYFLLCFL LKFSLTISSC LICFGFTLQS FCDSAQARNL TNCSSIMLSS 
      1360       1370       1380       1390       1400
NDERAPAWFE DFANGLLSAQ KLTAALIVLH TVFISITHVH RTKPLWRKSP 
      1410       1420       1430       1440       1450
LTNLWWAMTV PVVLLGQVVQ TAVDLQLWTH RDSRIHFGLE DVPLLTWLLG 
      1460       1470       1480       1490 
CLSLVLVVVT NEIVKLHEIR VRVRYQKRQK LQFETKLGMN SPF
Length:1,493
Mass (Da):166,177
Last modified:November 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA4B9059317486AA9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CABDUW010000121 Genomic DNA Translation: VTJ59361.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABDUW010000121 Genomic DNA Translation: VTJ59361.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR023298, ATPase_P-typ_TM_dom_sf
IPR039720, TMEM94
PANTHERiPTHR13219, PTHR13219, 1 hit
SUPFAMiSSF81665, SSF81665, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A5E4ARK6_MARMO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A5E4ARK6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2019
Last sequence update: November 13, 2019
Last modified: August 12, 2020
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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