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Entry version 2 (11 Dec 2019)
Sequence version 1 (13 Nov 2019)
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Protein
Submitted name:

Cytosine DNA methyltransferase

Gene

070

Organism
Frog virus 3 (FV-3)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferaseImported, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cytosine DNA methyltransferaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:070Imported, 074Imported, 077Imported, 080Imported, 081Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiFrog virus 3 (FV-3)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10493 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesIridoviridaeAlphairidovirinaeRanavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiDryophytes versicolor (chameleon treefrog) [TaxID: 30343]
Lithobates pipiens (Northern leopard frog) (Rana pipiens) [TaxID: 8404]
Notophthalmus viridescens (Eastern newt) (Triturus viridescens) [TaxID: 8316]
Oophaga pumilio (strawberry poison frog) [TaxID: 51950]
Rana sylvatica (Wood frog) [TaxID: 45438]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR018117 C5_DNA_meth_AS
IPR029063 SAM-dependent_MTases

Superfamily database of structural and functional annotation

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SUPFAMi
SSF53335 SSF53335, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS00094 C5_MTASE_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A5B8P1K2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRILDLFSGT HSVPKACAQR EGWSCVTVDL ADSDYNVDVL EWDYTKDLKP
60 70 80 90 100
REFDVVWASP PCRYFSKLRE SNIGRGGMTK KSVKEDLETK GLPLLRRAME
110 120 130 140 150
IIAYLQPKKF IVENPDTGRM KEYITEWPHY VVDYCAYSDW GYRKRTRLWT
160 170 180 190 200
DIEGFVPKTC AGKESCPNME RNPSSGRWRH VLATDAGGRG RKGTTRRLRY
210
RVPPAIIVEL LDLC
Length:214
Mass (Da):24,730
Last modified:November 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC0CB3D616F36A222
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
MK959604 Genomic DNA Translation: QDZ44454.1
MK959605 Genomic DNA Translation: QDZ44545.1
MK959606 Genomic DNA Translation: QDZ44628.1
MK959607 Genomic DNA Translation: QDZ44723.1
MK959608 Genomic DNA Translation: QDZ44818.1
MK959609 Genomic DNA Translation: QDZ44914.1
MK959610 Genomic DNA Translation: QDZ44998.1
MK959611 Genomic DNA Translation: QDZ45093.1
MK959612 Genomic DNA Translation: QDZ45187.1
MK959613 Genomic DNA Translation: QDZ45281.1
MK959614 Genomic DNA Translation: QDZ45375.1
MK959615 Genomic DNA Translation: QDZ45469.1
MK959616 Genomic DNA Translation: QDZ45563.1
MK959617 Genomic DNA Translation: QDZ45658.1
MK959618 Genomic DNA Translation: QDZ45745.1
MK959619 Genomic DNA Translation: QDZ45839.1
MK959620 Genomic DNA Translation: QDZ45933.1
MK959621 Genomic DNA Translation: QDZ46027.1

NCBI Reference Sequences

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RefSeqi
YP_031662.1, NC_005946.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
2947802

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MK959604 Genomic DNA Translation: QDZ44454.1
MK959605 Genomic DNA Translation: QDZ44545.1
MK959606 Genomic DNA Translation: QDZ44628.1
MK959607 Genomic DNA Translation: QDZ44723.1
MK959608 Genomic DNA Translation: QDZ44818.1
MK959609 Genomic DNA Translation: QDZ44914.1
MK959610 Genomic DNA Translation: QDZ44998.1
MK959611 Genomic DNA Translation: QDZ45093.1
MK959612 Genomic DNA Translation: QDZ45187.1
MK959613 Genomic DNA Translation: QDZ45281.1
MK959614 Genomic DNA Translation: QDZ45375.1
MK959615 Genomic DNA Translation: QDZ45469.1
MK959616 Genomic DNA Translation: QDZ45563.1
MK959617 Genomic DNA Translation: QDZ45658.1
MK959618 Genomic DNA Translation: QDZ45745.1
MK959619 Genomic DNA Translation: QDZ45839.1
MK959620 Genomic DNA Translation: QDZ45933.1
MK959621 Genomic DNA Translation: QDZ46027.1
RefSeqiYP_031662.1, NC_005946.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi2947802

Family and domain databases

InterProiView protein in InterPro
IPR018117 C5_DNA_meth_AS
IPR029063 SAM-dependent_MTases
SUPFAMiSSF53335 SSF53335, 1 hit
PROSITEiView protein in PROSITE
PS00094 C5_MTASE_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A5B8P1K2_FRG3V
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A5B8P1K2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2019
Last sequence update: November 13, 2019
Last modified: December 11, 2019
This is version 2 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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