Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 5 (22 Apr 2020)
Sequence version 1 (18 Sep 2019)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Kinetochore associated 1

Gene

EWB00_003395

Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Kinetochore associated 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:EWB00_003395Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchistosoma japonicum (Blood fluke)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6182 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000311919 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2100 – 2123DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili130 – 150Sequence analysisAdd BLAST21
Coiled coili596 – 616Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A4Z2DVT2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYDLFEAIEQ FEITIHEDLV PFSVPFIERY DKKVVAIRRT LFLFDCDFKV
60 70 80 90 100
TDSYEHDCNI VKVCSPPSVL FLFFLDEQGL FNVYLPEKRS LAFSLTHFGR
110 120 130 140 150
IFDLQLVTTS AVSFDLLLRS GDSLLLWRDI NSLQLHSELI EQNFEELNAR
160 170 180 190 200
FKSTERVAIT GKMFICCHLN PAVVWNLQLG SPSFITICLK ESSQFVVQSL
210 220 230 240 250
FDPFLVIEES ISLRKLSLIC DTIYCLALSY SGHLFLFNMF ASICLGCLNQ
260 270 280 290 300
FPRVHDFYIC STTSQSTFTE DNEFPGLHEI TIVILRDLEE NDQPSPSGPS
310 320 330 340 350
KLLELILFPS YQVIYRTNVS KDSWLLSDYD VGSYKAVSTG SQVLYAELLS
360 370 380 390 400
KRPDESLENF LSIKALRATN PKERLQHLLI SKNFEEARLL VKTFNLDCKD
410 420 430 440 450
FQLVVTTELE FLVNTIHKHD QGDDLYPRLL TCLQQTEELW KHLDIVESIL
460 470 480 490 500
RITMPKSDDQ LKLLLIIKEK LIIGNSEDMS TEHEDIGIKV LILLKRLKAF
510 520 530 540 550
LMIHGPDNYT IKTWVEFRDE NIYVIFARLF LSKSEGTSDL SQAFLFWILY
560 570 580 590 600
KGELSEFLTW DTLELLCNLL SKRPLTCFTS NHLQSGHQCD STNSPYQSQE
610 620 630 640 650
LELLESEEAI QKWIRNELLP VVIRQSPDAL PLLVKYLTQR VKELEACSFT
660 670 680 690 700
SNSNICVQEN KLKCPFSWPS TAISWINKFL DSVNISESIN QECVYNIGSV
710 720 730 740 750
ADLYLSGIAS RDPNVDPFYE LRKLAKQLET IKLLRDVYNC HLSIDFCEGE
760 770 780 790 800
TELSIAYRIL DVAFNLGTCF DNGIDKLTAR YLKDRNIDHQ TFFQGYSYDL
810 820 830 840 850
INRIRMAIQS SVLDEDCPPE WLGSPPKCKQ SNKEIILDQE PHILSQHACL
860 870 880 890 900
VAGWITVPSC RMKVVFDLAS VAPLPWSNDL ITLTESVLKQ ARVPSSCSQY
910 920 930 940 950
VDGLFHMMNK LERLCNIARL HEIFTRYGLK EFSLSDIGYG NTLWLADQAI
960 970 980 990 1000
SRILRSNEGP FNTNISFSTP RLDRSDTVYR DATTVAQKLL DQSQWPLLFA
1010 1020 1030 1040 1050
QLYMELALFK ALELNDAESI NFSDDYDNRI SFFITHLNFS TNEALHELFS
1060 1070 1080 1090 1100
HPNSKLLESS MQLTSIRDWL IRLTFRSIKH LLKHGNLLFP SQRSLIVDLG
1110 1120 1130 1140 1150
LSLASMRITL NSTEYKQNGT QMNWCHLMKF IKLYTTSPFD DSNLHDSEVS
1160 1170 1180 1190 1200
IILELFSNDK CVFGLLTDRL HIIRCLTKSY VEQVCSSIYE PTDIDKMFNF
1210 1220 1230 1240 1250
PMKLRSSYRL LLPDLPYGIL EELMTWQWFS LLCSSICTSS VAITSESCSQ
1260 1270 1280 1290 1300
SNLSVDHSSS LISQGLRVHS LLVKMMETLT NIHQTRLHSK ANCERIEVSS
1310 1320 1330 1340 1350
ISSYLVPTCY YCSCIWNRPL GRLGCVFELF MSFVFPFLLK VIKSIQLDEM
1360 1370 1380 1390 1400
SIRKSIVNIV QAVLSTFSSL LLWAGGQDQL NPLVEQKCIC RIFALTNEFQ
1410 1420 1430 1440 1450
ALRLVVQAFT SVFSQIDRAY QSTSGEKDPL ECLFCNSLYH EQTTTDVFHS
1460 1470 1480 1490 1500
KSQSNHLYNS LKWLANLLQW FTCHYSYTGD NNKIYDDTKN EENKVVRSNN
1510 1520 1530 1540 1550
TNIPRQILED GMKLASSWYL EFGLCLTGAH TLLIGIMNLI RSSVARNIWS
1560 1570 1580 1590 1600
DSFIFDLGLQ ELNNDVVGSC FDLCNQCLSS SLNSILNPSS GKYLDQPLAL
1610 1620 1630 1640 1650
SIALALPIEE ATTVVRNVVA QNKHTPKKIM AVANIIFMFS QITCKADLSL
1660 1670 1680 1690 1700
LQLSQTMANT WSWHIVLKPY KLNFSRLITH GIDHSSLEHI LDKLCRMIPS
1710 1720 1730 1740 1750
INEESVYIVP SEPRSESVSR ILNTTNERSL PPIKLIAEFA KDFNIPLKPY
1760 1770 1780 1790 1800
LFKHLNYLFR PCNGFVDPTV SVDGNFPFTG FDNNSNNTFL PTSTTEINGS
1810 1820 1830 1840 1850
NVNRFMCYQK VCLSRAHTIL KLLFRSAKQS DNSQHSFNEL ANLLQSFYAS
1860 1870 1880 1890 1900
TSPYDYERLS FLFSWIRTCC PKMIANKQIQ LLNFLRAYRR SHPPRDFELE
1910 1920 1930 1940 1950
RVSAGSESEH STLNGWGIYL CRPSCFSKSE GYHQLGNMRM PYHQLLDDSL
1960 1970 1980 1990 2000
PIKIIGPEIT SSNVNFWLRV NQSMEWNSSD LIKITAAQNL VNQYTIVGLL
2010 2020 2030 2040 2050
PVTNSNYVTE ELTVPRSVGW DRALPCQILI EPLFSKLHNL LETVESTFNV
2060 2070 2080 2090 2100
YSLLSGLSRR VIYGPHRLLV LRLARNLAKT YLLRADNEAR LVYARNKQSC
2110 2120 2130 2140 2150
STSKTCPNEE LLDSDSDESE KEPNENIRLA RIALEKAETS HKQFAIEGCL
2160 2170 2180 2190 2200
YEHHLADWEE VNKHFNSPFE LILNILYKAA SELQPSVTWN SRSGLPISEL
2210 2220 2230 2240 2250
FLRRRVIKAL PHIAELAQID LLDVAKHILV NRLKLPSRIF MNDGELNGSP
2260 2270 2280 2290 2300
ITNRSMLLDM TVECSEFSPN DISFNTTVYQ PQLSGVTSFE NQRSDQSEPK
2310 2320 2330 2340 2350
QEDFMLAELL LQSTRLKNEL LPILDIFVFA DTPNQYVSAK WRAARCILRS
2360 2370 2380 2390 2400
QSGLTLRPKL SFSELRSTLL RLSTLASCPT ATSQQLIFGA SFSCTSSRGD
2410 2420 2430 2440 2450
TFNSLCCTRL TNSMKQLLAS SSNTLTTIHF ASCLVLDYEL SSPPTITQLL
2460 2470 2480 2490 2500
EFINRLNAKE SLDYALLLLV FMESSPDVKG SMKWFLLNPV KQSCTLHYLL
2510 2520 2530 2540 2550
SSLIERILLR LLNREHSDSR KLHDFLNKLL CFLIAWPIPD KEIEAIFSQL
2560 2570 2580 2590 2600
SKSIIPVISQ QTIRLNVSLQ RIMIIISVFL RLLALSTLDK YTAVDLDLWF
2610 2620 2630
NLINENEGQN VTKFIRDAIL NSEICLTSKF LSCL
Length:2,634
Mass (Da):301,193
Last modified:September 18, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i166DC4E2BF226AFC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
SKCS01000021 Genomic DNA Translation: TNN20654.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
SKCS01000021 Genomic DNA Translation: TNN20654.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A4Z2DVT2_SCHJA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A4Z2DVT2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2019
Last sequence update: September 18, 2019
Last modified: April 22, 2020
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again