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UniProtKB - A0A4Z2DVT2 (A0A4Z2DVT2_SCHJA)

Entry version 5 (22 Apr 2020)
Sequence version 1 (18 Sep 2019)
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Protein
Submitted name:

Kinetochore associated 1

Gene

EWB00_003395

Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Kinetochore associated 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:EWB00_003395Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchistosoma japonicum (Blood fluke)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6182 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Trematoda › Digenea › Strigeidida › Schistosomatoidea › Schistosomatidae › Schistosoma
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000311919 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2100 – 2123DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili130 – 150Sequence analysisAdd BLAST21
Coiled coili596 – 616Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A4Z2DVT2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYDLFEAIEQ FEITIHEDLV PFSVPFIERY DKKVVAIRRT LFLFDCDFKV 
        60         70         80         90        100
TDSYEHDCNI VKVCSPPSVL FLFFLDEQGL FNVYLPEKRS LAFSLTHFGR 
       110        120        130        140        150
IFDLQLVTTS AVSFDLLLRS GDSLLLWRDI NSLQLHSELI EQNFEELNAR 
       160        170        180        190        200
FKSTERVAIT GKMFICCHLN PAVVWNLQLG SPSFITICLK ESSQFVVQSL 
       210        220        230        240        250
FDPFLVIEES ISLRKLSLIC DTIYCLALSY SGHLFLFNMF ASICLGCLNQ 
       260        270        280        290        300
FPRVHDFYIC STTSQSTFTE DNEFPGLHEI TIVILRDLEE NDQPSPSGPS 
       310        320        330        340        350
KLLELILFPS YQVIYRTNVS KDSWLLSDYD VGSYKAVSTG SQVLYAELLS 
       360        370        380        390        400
KRPDESLENF LSIKALRATN PKERLQHLLI SKNFEEARLL VKTFNLDCKD 
       410        420        430        440        450
FQLVVTTELE FLVNTIHKHD QGDDLYPRLL TCLQQTEELW KHLDIVESIL 
       460        470        480        490        500
RITMPKSDDQ LKLLLIIKEK LIIGNSEDMS TEHEDIGIKV LILLKRLKAF 
       510        520        530        540        550
LMIHGPDNYT IKTWVEFRDE NIYVIFARLF LSKSEGTSDL SQAFLFWILY 
       560        570        580        590        600
KGELSEFLTW DTLELLCNLL SKRPLTCFTS NHLQSGHQCD STNSPYQSQE 
       610        620        630        640        650
LELLESEEAI QKWIRNELLP VVIRQSPDAL PLLVKYLTQR VKELEACSFT 
       660        670        680        690        700
SNSNICVQEN KLKCPFSWPS TAISWINKFL DSVNISESIN QECVYNIGSV 
       710        720        730        740        750
ADLYLSGIAS RDPNVDPFYE LRKLAKQLET IKLLRDVYNC HLSIDFCEGE 
       760        770        780        790        800
TELSIAYRIL DVAFNLGTCF DNGIDKLTAR YLKDRNIDHQ TFFQGYSYDL 
       810        820        830        840        850
INRIRMAIQS SVLDEDCPPE WLGSPPKCKQ SNKEIILDQE PHILSQHACL 
       860        870        880        890        900
VAGWITVPSC RMKVVFDLAS VAPLPWSNDL ITLTESVLKQ ARVPSSCSQY 
       910        920        930        940        950
VDGLFHMMNK LERLCNIARL HEIFTRYGLK EFSLSDIGYG NTLWLADQAI 
       960        970        980        990       1000
SRILRSNEGP FNTNISFSTP RLDRSDTVYR DATTVAQKLL DQSQWPLLFA 
      1010       1020       1030       1040       1050
QLYMELALFK ALELNDAESI NFSDDYDNRI SFFITHLNFS TNEALHELFS 
      1060       1070       1080       1090       1100
HPNSKLLESS MQLTSIRDWL IRLTFRSIKH LLKHGNLLFP SQRSLIVDLG 
      1110       1120       1130       1140       1150
LSLASMRITL NSTEYKQNGT QMNWCHLMKF IKLYTTSPFD DSNLHDSEVS 
      1160       1170       1180       1190       1200
IILELFSNDK CVFGLLTDRL HIIRCLTKSY VEQVCSSIYE PTDIDKMFNF 
      1210       1220       1230       1240       1250
PMKLRSSYRL LLPDLPYGIL EELMTWQWFS LLCSSICTSS VAITSESCSQ 
      1260       1270       1280       1290       1300
SNLSVDHSSS LISQGLRVHS LLVKMMETLT NIHQTRLHSK ANCERIEVSS 
      1310       1320       1330       1340       1350
ISSYLVPTCY YCSCIWNRPL GRLGCVFELF MSFVFPFLLK VIKSIQLDEM 
      1360       1370       1380       1390       1400
SIRKSIVNIV QAVLSTFSSL LLWAGGQDQL NPLVEQKCIC RIFALTNEFQ 
      1410       1420       1430       1440       1450
ALRLVVQAFT SVFSQIDRAY QSTSGEKDPL ECLFCNSLYH EQTTTDVFHS 
      1460       1470       1480       1490       1500
KSQSNHLYNS LKWLANLLQW FTCHYSYTGD NNKIYDDTKN EENKVVRSNN 
      1510       1520       1530       1540       1550
TNIPRQILED GMKLASSWYL EFGLCLTGAH TLLIGIMNLI RSSVARNIWS 
      1560       1570       1580       1590       1600
DSFIFDLGLQ ELNNDVVGSC FDLCNQCLSS SLNSILNPSS GKYLDQPLAL 
      1610       1620       1630       1640       1650
SIALALPIEE ATTVVRNVVA QNKHTPKKIM AVANIIFMFS QITCKADLSL 
      1660       1670       1680       1690       1700
LQLSQTMANT WSWHIVLKPY KLNFSRLITH GIDHSSLEHI LDKLCRMIPS 
      1710       1720       1730       1740       1750
INEESVYIVP SEPRSESVSR ILNTTNERSL PPIKLIAEFA KDFNIPLKPY 
      1760       1770       1780       1790       1800
LFKHLNYLFR PCNGFVDPTV SVDGNFPFTG FDNNSNNTFL PTSTTEINGS 
      1810       1820       1830       1840       1850
NVNRFMCYQK VCLSRAHTIL KLLFRSAKQS DNSQHSFNEL ANLLQSFYAS 
      1860       1870       1880       1890       1900
TSPYDYERLS FLFSWIRTCC PKMIANKQIQ LLNFLRAYRR SHPPRDFELE 
      1910       1920       1930       1940       1950
RVSAGSESEH STLNGWGIYL CRPSCFSKSE GYHQLGNMRM PYHQLLDDSL 
      1960       1970       1980       1990       2000
PIKIIGPEIT SSNVNFWLRV NQSMEWNSSD LIKITAAQNL VNQYTIVGLL 
      2010       2020       2030       2040       2050
PVTNSNYVTE ELTVPRSVGW DRALPCQILI EPLFSKLHNL LETVESTFNV 
      2060       2070       2080       2090       2100
YSLLSGLSRR VIYGPHRLLV LRLARNLAKT YLLRADNEAR LVYARNKQSC 
      2110       2120       2130       2140       2150
STSKTCPNEE LLDSDSDESE KEPNENIRLA RIALEKAETS HKQFAIEGCL 
      2160       2170       2180       2190       2200
YEHHLADWEE VNKHFNSPFE LILNILYKAA SELQPSVTWN SRSGLPISEL 
      2210       2220       2230       2240       2250
FLRRRVIKAL PHIAELAQID LLDVAKHILV NRLKLPSRIF MNDGELNGSP 
      2260       2270       2280       2290       2300
ITNRSMLLDM TVECSEFSPN DISFNTTVYQ PQLSGVTSFE NQRSDQSEPK 
      2310       2320       2330       2340       2350
QEDFMLAELL LQSTRLKNEL LPILDIFVFA DTPNQYVSAK WRAARCILRS 
      2360       2370       2380       2390       2400
QSGLTLRPKL SFSELRSTLL RLSTLASCPT ATSQQLIFGA SFSCTSSRGD 
      2410       2420       2430       2440       2450
TFNSLCCTRL TNSMKQLLAS SSNTLTTIHF ASCLVLDYEL SSPPTITQLL 
      2460       2470       2480       2490       2500
EFINRLNAKE SLDYALLLLV FMESSPDVKG SMKWFLLNPV KQSCTLHYLL 
      2510       2520       2530       2540       2550
SSLIERILLR LLNREHSDSR KLHDFLNKLL CFLIAWPIPD KEIEAIFSQL 
      2560       2570       2580       2590       2600
SKSIIPVISQ QTIRLNVSLQ RIMIIISVFL RLLALSTLDK YTAVDLDLWF 
      2610       2620       2630 
NLINENEGQN VTKFIRDAIL NSEICLTSKF LSCL
Length:2,634
Mass (Da):301,193
Last modified:September 18, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i166DC4E2BF226AFC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
SKCS01000021 Genomic DNA Translation: TNN20654.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
SKCS01000021 Genomic DNA Translation: TNN20654.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A4Z2DVT2_SCHJA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A4Z2DVT2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2019
Last sequence update: September 18, 2019
Last modified: April 22, 2020
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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