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Entry version 5 (22 Apr 2020)
Sequence version 1 (18 Sep 2019)
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Protein
Submitted name:

Centrosomal protein

Gene

EWB00_007010

Organism
Schistosoma japonicum (Blood fluke)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Centrosomal proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:EWB00_007010Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchistosoma japonicum (Blood fluke)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6182 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaSpiraliaLophotrochozoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000311919 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni534 – 564DisorderedSequence analysisAdd BLAST31
Regioni871 – 938DisorderedSequence analysisAdd BLAST68
Regioni997 – 1026DisorderedSequence analysisAdd BLAST30
Regioni1039 – 1063DisorderedSequence analysisAdd BLAST25
Regioni1218 – 1265DisorderedSequence analysisAdd BLAST48
Regioni1532 – 1567DisorderedSequence analysisAdd BLAST36
Regioni1838 – 1876DisorderedSequence analysisAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili60 – 80Sequence analysisAdd BLAST21
Coiled coili267 – 287Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi534 – 549PolarSequence analysisAdd BLAST16
Compositional biasi872 – 938PolarSequence analysisAdd BLAST67
Compositional biasi1039 – 1054PolarSequence analysisAdd BLAST16
Compositional biasi1553 – 1567PolarSequence analysisAdd BLAST15
Compositional biasi1838 – 1863PolarSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A4Z2CW57-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEYPTSPYG PSLLELRQLK HEEIERRKKM RILQVRSQAK ESARKVRMLY
60 70 80 90 100
NVKKQQLSDL VAKKLQIKLA KDDIKLLEAK KCEYINVMQL YGIGHKSAEN
110 120 130 140 150
WNNPVLETNQ NLSVARKRAE DRFNMALNKL HEERLNEDLI QHETQKRIKE
160 170 180 190 200
VRNVEKKRAA LIASLPPSRS VLIKENSKPT LAYEPLVLVY DIEARNAIHT
210 220 230 240 250
QNMSSKVLVN NIKVDEATAV GDKKAQNATI SAYKEEERIQ AVERENNIHA
260 270 280 290 300
QEDLIKADMR GRQAMRKERI HQHYQALLNR LDEIRRNETL LRRSQLYSGT
310 320 330 340 350
IENSHMPGGP WDETVINRRA EKIFEDELLH QLTNINHEDC ADVIDEENIV
360 370 380 390 400
DSNNNHIDKC NQVLDIDSEI NNLPVKDVTS KSDHNLLDHQ ISLSNEPILE
410 420 430 440 450
LDLNDEFSFH DEEHLSTKEE EITPNEEIPA KYTDLGPGER PTLPDIRRCR
460 470 480 490 500
ILSGSINLTN PTHDVNSNNC TTSKPVHRNF NTPSQSIVSS KTSFEDKLTS
510 520 530 540 550
DVFAESGDMQ LRQRLLDEEL EMIDKRINRL RFNSSLDPQE NQSHSVRSSE
560 570 580 590 600
SFKEPNKTTR NTTPRNMYII EGCIYKDNAV SNTKDSFHSP GHISSTKYET
610 620 630 640 650
ETSLSSIIPQ PNGTPPVNLL FSESIPTDQK ISSCMAFANQ NFDNNQSTVV
660 670 680 690 700
KYCISKPITG VLAERARDLV RIQKAELLNC EKSKSFITES SQSFRSSSQS
710 720 730 740 750
SIDAIDFQFS AHSSSTNNEM HENEDVSCFI PESDTNQMMN HSSITGSDKH
760 770 780 790 800
NWDINDNKHL SKHSLQQMNV SVYESSTLST STPVVSYKPV QSLQSHCDVQ
810 820 830 840 850
DVSHFDEVID VVAGDVVQDV DKMPVHDSSF EVVTSINDLS IMNSQCYNHL
860 870 880 890 900
HEPSNIQLLN GTDKRLETKI PTESLSDQPH KIPSQSTSLV DISSKNKLSS
910 920 930 940 950
STTTLSPQSS LNSPSSIGSK QTILLSSSDK PQSSESCTSD TLKAELKALL
960 970 980 990 1000
TSSLLNSILS YNSSGLTTDT NDLKKLFSSQ SFLLSSLSGV YRDAKVQTNE
1010 1020 1030 1040 1050
NSSENEMNHP ITSISSTSSL SNPSVSSLNQ INSKITQLNK LSDHNASNQE
1060 1070 1080 1090 1100
SDTKSIDRPL CDGHTEDIPV NNDHADKLPI NDDVIKAVKQ RILNKYLQTN
1110 1120 1130 1140 1150
KEWLINLSSS NRGKLSHTRS STSSSSSSGV EFHYLSEATD TNEINWSENK
1160 1170 1180 1190 1200
SDSFLHSEQV SANKSSSFPE TYDCVSFSPQ TYTPLSNQSA RFKPLPRLEE
1210 1220 1230 1240 1250
AISEESLHTI QVVSDFNNLS SNTPSSWTES RKSSEFGNLS QYSATNRTSG
1260 1270 1280 1290 1300
PGISLKNENE NSPNHNVVNN GTCSHQSSEE NDTIQQLLSN IPDTPIDESN
1310 1320 1330 1340 1350
KAEIIPCIGS KLSLLTTSSE KLDNARLLTE DCDQNVVECS LPHNSQHDNG
1360 1370 1380 1390 1400
ATNEPSVIVN NEDSKDEIPV ENSSILCLKL NSRPSSPAEG AVSKFSPRYH
1410 1420 1430 1440 1450
QIDDFNVSSS LPSVHVESLL DRCEKYQIYA ETVHCASDSN LKPPSQTNEA
1460 1470 1480 1490 1500
SVTDSLLSFQ RHEEHCNMLS INLQTQKADD PKCQLPNVSS NNINSDNVSL
1510 1520 1530 1540 1550
AKDTLQDKPL TGKPTNNHSK FSITKHKTKD SMINHSNGLR TNHVVKGSGT
1560 1570 1580 1590 1600
RKPDPFVSNS SKQRTTHSKI VRNAVSTGQK SIKFKYPKVN IPSSSTNTIT
1610 1620 1630 1640 1650
KTPSKQTSTT NSLAKRQTSV PVCTKNLTIT SCSQQTKPFE SYSCMKLNPF
1660 1670 1680 1690 1700
NQAKTLQMEL TQWQQKRLRC HKVSDDKDTM SKITTIPSSI SNDVNNDNTN
1710 1720 1730 1740 1750
IESVSDSDVI NFGSKFIPDI IQDENKQQQT QNSNIMKFTS SSISNRNRSP
1760 1770 1780 1790 1800
VELTVDNVTQ QLASCFVDID ASICSGEKSL NKPASEINIP IDQSKLAFEA
1810 1820 1830 1840 1850
PNDANVQLIS EIPPDTFSYL KKSSNFSVKT ISSKASTSLS SSSKLHEQQH
1860 1870 1880 1890
DSLISAQSRH QQAHANRQRV KEYDRPNHVP KSCCIPTCLY KRFTTYRE
Length:1,898
Mass (Da):212,437
Last modified:September 18, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB13B588E526BFBA4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
SKCS01000408 Genomic DNA Translation: TNN08479.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
SKCS01000408 Genomic DNA Translation: TNN08479.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A4Z2CW57_SCHJA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A4Z2CW57
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 18, 2019
Last sequence update: September 18, 2019
Last modified: April 22, 2020
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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