UniProtKB - A0A4U9MDT0 (A0A4U9MDT0_HAEHA)
Protein
Bifunctional protein PyrR
Gene
pyrR
Organism
Haemophilus haemolyticus
Status
Functioni
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.UniRule annotation
Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.UniRule annotation
Catalytic activityi
- EC:2.4.2.9UniRule annotation
GO - Molecular functioni
- uracil phosphoribosyltransferase activity Source: UniProtKB-UniRule
GO - Biological processi
- nucleoside metabolic process Source: InterPro
- regulation of transcription, DNA-templated Source: UniProtKB-UniRule
Keywordsi
Molecular function | GlycosyltransferaseUniRule annotationImported, Transferase |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Bifunctional protein PyrRUniRule annotationIncluding the following 2 domains: Pyrimidine operon regulatory proteinUniRule annotation Uracil phosphoribosyltransferaseUniRule annotation (EC:2.4.2.9UniRule annotation) Short name: UPRTaseUniRule annotation |
Gene namesi | Name:pyrRUniRule annotationImported ORF Names:NCTC10659_00085Imported |
Organismi | Haemophilus haemolyticusImported |
Taxonomic identifieri | 726 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus |
Proteomesi |
|
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 4 – 147 | PribosyltranInterPro annotationAdd BLAST | 144 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 93 – 105 | PRPP-bindingUniRule annotationAdd BLAST | 13 |
Sequence similaritiesi
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.UniRule annotationARBA annotation
Family and domain databases
CDDi | cd06223, PRTases_typeI, 1 hit |
Gene3Di | 3.40.50.2020, 1 hit |
HAMAPi | MF_01219, PyrR, 1 hit |
InterProi | View protein in InterPro IPR000836, PRibTrfase_dom IPR029057, PRTase-like IPR023050, PyrR |
Pfami | View protein in Pfam PF00156, Pribosyltran, 1 hit |
SUPFAMi | SSF53271, SSF53271, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A4U9MDT0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKTKEVVDEL TVKRAITRIT YEIIERNKDL NKIVLAGIKT RGVFIAHRIQ
60 70 80 90 100
ERLKQLENLS VPVVELDTKP FRDDVKSGED TSLVSVDVTD REVILVDDVL
110 120 130 140 150
YTGRTIRAAI DNIVGHGRPA RVSLAVLVDR GHRELPIRPD YVGKNIPTSR
160 170
SEEIIVEMTE LDDQDRVLIT EEA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CABEEK010000001 Genomic DNA Translation: VTQ34518.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CABEEK010000001 Genomic DNA Translation: VTQ34518.1 |
3D structure databases
SMRi | A0A4U9MDT0 |
ModBasei | Search... |
Family and domain databases
CDDi | cd06223, PRTases_typeI, 1 hit |
Gene3Di | 3.40.50.2020, 1 hit |
HAMAPi | MF_01219, PyrR, 1 hit |
InterProi | View protein in InterPro IPR000836, PRibTrfase_dom IPR029057, PRTase-like IPR023050, PyrR |
Pfami | View protein in Pfam PF00156, Pribosyltran, 1 hit |
SUPFAMi | SSF53271, SSF53271, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A4U9MDT0_HAEHA | |
Accessioni | A0A4U9MDT0Primary (citable) accession number: A0A4U9MDT0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 31, 2019 |
Last sequence update: | July 31, 2019 | |
Last modified: | October 7, 2020 | |
This is version 8 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |