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UniProtKB - A0A4S2L4X5 (A0A4S2L4X5_OPIFE)

Entry version 6 (12 Aug 2020)
Sequence version 1 (31 Jul 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

CRM22_009864

Organism
Opisthorchis felineus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CRM22_009864Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOpisthorchis felineusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri147828 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Spiralia › Lophotrochozoa › Platyhelminthes › Trematoda › Digenea › Opisthorchiida › Opisthorchiata › Opisthorchiidae › Opisthorchis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000308267 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Integrator subunit 2 family.ARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2

The PANTHER Classification System

More...PANTHERi		PTHR28608, PTHR28608, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14750, INTS2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR02105, INTSUBUNIT2

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A4S2L4X5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNIFIAGTAH FCAVSGRSSV VKRQLPFDIN KDKTTTDCLA IVQFRWEKRK 
        60         70         80         90        100
TTTLTEDVIF GAPSLSGLQF PLLNTIYQPY PMRSIMGDLR CADPSDILDL 
       110        120        130        140        150
LPLLYFSKVD LEDDLLNVSL PYDVAYMLRE NLHFLTQLRQ LNLLDLWSSV 
       160        170        180        190        200
KSEESSCSGV NVSTMEYEAQ NVAGKAKLFF RLLYHLLYTH ASQPCFSQPC 
       210        220        230        240        250
VDLLQLEPFE FELIAFMCST VYGIPDFPIL PAFVCGYISH ANHTNFHLLK 
       260        270        280        290        300
RLFRNIPFEW FTVWNWLIRL SEQLSLGVTV PEILHSCGTS SSADEPGFLF 
       310        320        330        340        350
SLSTELDRNL LLHRIEGTIR SLLLVCPNYT RMVIERCLSI HCFPGLVVDA 
       360        370        380        390        400
LFFLDKSDDN SLLIYLKRML LDSGTRTRSW ISGYLKRQMG ADGHLEMFSQ 
       410        420        430        440        450
YFIKSSASLI PNDPSIPLTN DVILKALLLL RVLAAMRGFV NYIFPPTLSS 
       460        470        480        490        500
QLLTLLTHKT VDSERGSQYI TYSLAFLIGL RSSLQVPQDV IVRTGSSSDI 
       510        520        530        540        550
ENQIVVWLQG LINRQTHVPP AGLSNEQHSI ILNTPNNRPY AETLLLLAIL 
       560        570        580        590        600
FHTNQPGPIT DLISNLLGLR IPSLGRTVNG WRKIFLQSVF TESMIASQVA 
       610        620        630        640        650
RVPITPLLNR SLSTHLPIQC ALQLLKSHAF AKNKLEIKDW LVGQIRQSVR 
       660        670        680        690        700
PMHPLLPDLV EAHIVHSFGT SSTPGCISEP SALISERELI AQIQNGAKYP 
       710        720        730        740        750
LAQLCSPSLD MTCKDSTPPT DSTQVDFTAE LLFLYYALYV YDYQIASRLL 
       760        770        780        790        800
SNRHCLPGEA PCVYSDQLWD CIPITYLLRH ARSNVTDYGP LYPRLLQLVT 
       810        820        830        840        850
NHFPNLTVGE LMIQDELLLD PIWCPQVKRF SAPAQQSVPD ELTIDSTQLH 
       860        870        880        890        900
CATNTINICS PTELDEAFEA VLTHIIPLCE SGEDQRPSQA ILTRTSVHHL 
       910        920        930        940        950
IRLIQRLSQA VEQLSVDCLL PFGPVLGHQC PRLLLAANKH PLFTTNRRFV 
       960        970        980        990       1000
CRLEYLWCRL HLVMPRKLEL LTVNALLDGV NSKKPSCSSL RCIRSVKKLT 
      1010       1020       1030       1040       1050
GADIRIDPVE SLMNTVDRGV FRCPPVLRMF LRILESNLLA SRSYWGHRLL 
      1060       1070       1080       1090       1100
ERVVNLPAST GAPFGSVTNT VTLPSVQSGN NSESALDSSL PNLPTTTSFV 
      1110       1120       1130       1140       1150
NAAASARTIA PVSDEECEVL CSNMLLTQNA TVVQLLLEHC LPRKEESTLR 
      1160       1170       1180       1190       1200
SQISVLREVQ NIVCTYVHSM FIAEPALAEV IVWQTFPHSL LPISTQAIPS 
      1210       1220       1230       1240       1250
LHICLDSVLH VYRLSGDYAK MVFCLDLVSH LSLHYNIQSA FERAAFMIDS 
      1260       1270       1280       1290       1300
LFHLLSSVVC ADDRPDLLQA CLPAFLRLGG AFPSLAPVIV RLLLTVGTLI 
      1310       1320       1330       1340       1350
SSVLPDEARD RLRLRTSDEK RPEPATWTAA TYDLPLLDRS MLCLEHVMWT 
      1360       1370 
FDKLIHRCSA QRYLYYPPEL TC
Length:1,372
Mass (Da):154,132
Last modified:July 31, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEB07662E41848BE8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A4S2L4D3A0A4S2L4D3_OPIFE
Uncharacterized protein
CRM22_009864
1,422Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A4S2L4Q6A0A4S2L4Q6_OPIFE
Uncharacterized protein
CRM22_009864
968Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A4V3SCS1A0A4V3SCS1_OPIFE
Uncharacterized protein
CRM22_009864
886Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
SJOL01009403 Genomic DNA Translation: TGZ57813.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
SJOL01009403 Genomic DNA Translation: TGZ57813.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR026236, Int2_metazoa
IPR029321, INTS2
PANTHERiPTHR28608, PTHR28608, 1 hit
PfamiView protein in Pfam
PF14750, INTS2, 1 hit
PRINTSiPR02105, INTSUBUNIT2

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A4S2L4X5_OPIFE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A4S2L4X5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 31, 2019
Last sequence update: July 31, 2019
Last modified: August 12, 2020
This is version 6 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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