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UniProtKB - A0A4S2E4D2 (A0A4S2E4D2_9PAST)
Protein
Deoxyribose-phosphate aldolase
Gene
deoC
Organism
Pasteurella caecimuris
Status
Functioni
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
UniRule annotationCaution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
Catalytic activityi
- 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphateUniRule annotationARBA annotationEC:4.1.2.4UniRule annotationARBA annotation
: 2-deoxy-D-ribose 1-phosphate degradation Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation This subpathway is part of the pathway 2-deoxy-D-ribose 1-phosphate degradation, which is itself part of Carbohydrate degradation.View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate, the pathway 2-deoxy-D-ribose 1-phosphate degradation and in Carbohydrate degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 92 | Proton donor/acceptorUniRule annotation | 1 | |
Active sitei | 154 | Schiff-base intermediate with acetaldehydeUniRule annotation | 1 | |
Active sitei | 182 | Proton donor/acceptorUniRule annotation | 1 |
GO - Molecular functioni
- deoxyribose-phosphate aldolase activity Source: UniProtKB-UniRule
GO - Biological processi
- carbohydrate catabolic process Source: UniProtKB-UniRule
- deoxyribonucleotide catabolic process Source: InterPro
- deoxyribose phosphate catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | LyaseUniRule annotationImported |
Ligand | Schiff baseUniRule annotation |
Enzyme and pathway databases
UniPathwayi | UPA00002;UER00468 |
Names & Taxonomyi
Protein namesi | Recommended name: Deoxyribose-phosphate aldolaseUniRule annotation (EC:4.1.2.4UniRule annotation)Short name: DERAUniRule annotation Alternative name(s): 2-deoxy-D-ribose 5-phosphate aldolaseUniRule annotation PhosphodeoxyriboaldolaseUniRule annotation Short name: DeoxyriboaldolaseUniRule annotation |
Gene namesi | Name:deoCUniRule annotation ORF Names:E5343_04555Imported |
Organismi | Pasteurella caecimurisImported |
Taxonomic identifieri | 1796644 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Pasteurella |
Proteomesi |
|
Subcellular locationi
Cytoplasm and Cytosol
- Cytoplasm UniRule annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationStructurei
Family & Domainsi
Sequence similaritiesi
Family and domain databases
CDDi | cd00959, DeoC, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00114, DeoC_type1, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR011343, DeoC IPR002915, DeoC/FbaB/LacD_aldolase IPR028581, DeoC_typeI |
PANTHERi | PTHR10889, PTHR10889, 1 hit PTHR10889:SF1, PTHR10889:SF1, 1 hit |
Pfami | View protein in Pfam PF01791, DeoC, 1 hit |
PIRSFi | PIRSF001357, DeoC, 1 hit |
SMARTi | View protein in SMART SM01133, DeoC, 1 hit |
TIGRFAMsi | TIGR00126, deoC, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A4S2E4D2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDSKSLAKYI DHTALTAEKN EQDILTLCDE AMKYGFYSVC INSGYISLAK
60 70 80 90 100
EKLAGSEVKI CTVVGFPLGA NLTSVKAFET QEAIKAGTNE IDMVINVGWI
110 120 130 140 150
KSNKWQAVKE DIQAVLNACN GVPLKVILET CLLSKEEIIK ACEICRELGV
160 170 180 190 200
IFVKTSTGFS KGGATVEDVA LMKKIVGNIG VKASGGVRDT KTALAMIEAG
210 220
ATRIGASAGI AIISNSSDTQ STY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | SRYN01000004 Genomic DNA Translation: TGY50146.1 |
Genome annotation databases
EnsemblBacteriai | TGY50146; TGY50146; E5343_04555 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | SRYN01000004 Genomic DNA Translation: TGY50146.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblBacteriai | TGY50146; TGY50146; E5343_04555 |
Enzyme and pathway databases
UniPathwayi | UPA00002;UER00468 |
Family and domain databases
CDDi | cd00959, DeoC, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_00114, DeoC_type1, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR011343, DeoC IPR002915, DeoC/FbaB/LacD_aldolase IPR028581, DeoC_typeI |
PANTHERi | PTHR10889, PTHR10889, 1 hit PTHR10889:SF1, PTHR10889:SF1, 1 hit |
Pfami | View protein in Pfam PF01791, DeoC, 1 hit |
PIRSFi | PIRSF001357, DeoC, 1 hit |
SMARTi | View protein in SMART SM01133, DeoC, 1 hit |
TIGRFAMsi | TIGR00126, deoC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A4S2E4D2_9PAST | |
Accessioni | A0A4S2E4D2Primary (citable) accession number: A0A4S2E4D2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 31, 2019 |
Last sequence update: | July 31, 2019 | |
Last modified: | May 25, 2022 | |
This is version 9 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |