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Entry version 9 (02 Jun 2021)
Sequence version 1 (31 Jul 2019)
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Protein

BIG2 domain-containing protein

Gene

DXH47_03945

Organism
Levilactobacillus suantsaii
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
BIG2 domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DXH47_03945Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLevilactobacillus suantsaiiImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri2292255 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLevilactobacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000290602 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 46Sequence analysisAdd BLAST46
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_502080238347 – 1477BIG2 domain-containing proteinSequence analysisAdd BLAST1431

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1282 – 1359BIG2InterPro annotationAdd BLAST78

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni54 – 141DisorderedSequence analysisAdd BLAST88

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003343, Big_2
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR008964, Invasin/intimin_cell_adhesion
IPR022263, KxYKxGKxW

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00635, BID_2, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 1 hit
SSF49373, SSF49373, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03715, KxYKxGKxW, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A4Q0VKC7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKFMRNKAFY GDPKLRYKMF KVGKIWVFTA MASFSLLGAP QMMAHADTSA
60 70 80 90 100
QAESSSVVTK DTTTESEIQS NSSSTSSAAT SSSAASSSSS STSSSSATSS
110 120 130 140 150
SATSSSSSST SSSSATSSSA ASSSSSSTSS SSATSSSASS AASSSVTVAS
160 170 180 190 200
EALSSATTSS SATSAVSAAT TESSQTSAVA TSTATADQTI NSAASSAAAT
210 220 230 240 250
VADVTLTTNI TSAVTQTTTT SKSATTAVAT AATVSSAAST ESAAALTAED
260 270 280 290 300
KLSSEYASVA TAAASTAASA SSAAMAASSY AEIFNTSGAS SVSTDNPVSA
310 320 330 340 350
ANSVAQSAYI ATSTAADLAL HYNSLASMYI DALDVASVPS DMSISYGKAS
360 370 380 390 400
TAADSYVQAA VSYASVATSA AEAAELAAAQ NLNSLVSSTN STTYSEASAA
410 420 430 440 450
NSMATTASAA ASAAYESMQY DKTNSTAANA YSQANSAAKV ASSAAITANS
460 470 480 490 500
LATAAQAAYS TANSAAESGD YTAASDALVT AQTLASQSSD NYAIASTATS
510 520 530 540 550
TAESAASLAT TTTVSTAASM ASSSAQLAAS SATDATSYAS DAAQYSGGSQ
560 570 580 590 600
SALYVVAASE YASTAQSAAA VASSAASAAA VASTTKEANS LYRVASSAAN
610 620 630 640 650
TTQEATLQAS SAAMYAQEFY ADVDNAQTGE DSSVSVAVDV TNDTLSVGDS
660 670 680 690 700
VNIDATVSNS ASLSSTSNIT YTWYMSTDGK TWTQVQTSAS TTSSKTDSYT
710 720 730 740 750
ATIASAGTYY YQLLVTGKKG LLGTSFSVAS DVVTVVVTDE NGDYTTQAKS
760 770 780 790 800
SASLASDYAS AANSAATAAS SAIDNMYDIA NVSGVTPSSY ATKAVASYNE
810 820 830 840 850
ASSYATLATS AATAASEAQS LAAENETNGS YDLASSYAVN AASYATVASS
860 870 880 890 900
YSVQTSTAAS TALSYVDTAL QKAAAGSGQD STANYLASSY AETAASLASA
910 920 930 940 950
ASSVATIANS HANDANNAYS SAPDFNSTAT DYMNAANSAA SAAASNAAAA
960 970 980 990 1000
SSAASLAATF TGSDFAEASS AADDANTYLA LVNDNLSAAS SAAAAATQSV
1010 1020 1030 1040 1050
VDAQSSYTNS VATAATEAAS AANELGSSAA SVASSLAAAN TTNTSLGASY
1060 1070 1080 1090 1100
TAMTASYAQD AQSAAAMGSE AASAATSYMT MASSAVAAGS FNEASSYVTA
1110 1120 1130 1140 1150
ANDAMSEASS YATAATTAAS LGSSAAVDAV NYSNNLSSWQ SKPTGDATKI
1160 1170 1180 1190 1200
FGWTVLGGIT QQPATVTSTT SGSTFTLTGA ARTGAIAVNG ATKAYWYVQY
1210 1220 1230 1240 1250
NGEWYNLTTG NVPDVITVSQ AANTSVWDLA NLSSTLTVTV DSSFTGNLTF
1260 1270 1280 1290 1300
QFRAAYGLST ISYTTNYYSN LAEVDVYDKD IDASGIEVSG DDYLLNTETG
1310 1320 1330 1340 1350
VYTATTNPGN ATGTITWTSS DTSIATINDD GYVAPVTGAS GTITLTATIT
1360 1370 1380 1390 1400
NADGTTYSAS KEITIGSGLE DQTVDAGSKL DWKPVGGTTS DDDSVTYQWY
1410 1420 1430 1440 1450
YSTTDATSGG TAISGATDAT LSLSNVKSSD AGYYYLVVTS GTATTTLGAG
1460 1470
QLTVNATASE AASSSATMAS SAANEAG
Length:1,477
Mass (Da):145,410
Last modified:July 31, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE8C275F8C85BC483
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
QXIL01000005 Genomic DNA Translation: RXI79203.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
QXIL01000005 Genomic DNA Translation: RXI79203.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR003343, Big_2
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR008964, Invasin/intimin_cell_adhesion
IPR022263, KxYKxGKxW
SMARTiView protein in SMART
SM00635, BID_2, 1 hit
SUPFAMiSSF48726, SSF48726, 1 hit
SSF49373, SSF49373, 1 hit
TIGRFAMsiTIGR03715, KxYKxGKxW, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A4Q0VKC7_9LACO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A4Q0VKC7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 31, 2019
Last sequence update: July 31, 2019
Last modified: June 2, 2021
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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