UniProtKB - A0A4P6PYL7 (A0A4P6PYL7_9ACTN)
Protein
Isoprenyl transferase
Gene
EKD16_07660
Organism
Streptomonospora sp. M2
Status
Functioni
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.UniRule annotation
Cofactori
Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 42 | UniRule annotation | 1 | |
Metal bindingi | 42 | MagnesiumUniRule annotation | 1 | |
Binding sitei | 47 | SubstrateUniRule annotation | 1 | |
Binding sitei | 55 | SubstrateUniRule annotation | 1 | |
Binding sitei | 59 | SubstrateUniRule annotation | 1 | |
Active sitei | 90 | Proton acceptorUniRule annotation | 1 | |
Binding sitei | 91 | SubstrateUniRule annotation | 1 | |
Binding sitei | 93 | SubstrateUniRule annotation | 1 | |
Binding sitei | 210 | SubstrateUniRule annotation | 1 | |
Metal bindingi | 229 | MagnesiumUniRule annotation | 1 |
GO - Molecular functioni
- magnesium ion binding Source: UniProtKB-UniRule
- prenyltransferase activity Source: UniProtKB-UniRule
Keywordsi
Molecular function | TransferaseUniRule annotationImportedARBA annotation |
Ligand | MagnesiumUniRule annotation, Metal-bindingUniRule annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:EKD16_07660Imported |
Organismi | Streptomonospora sp. M2Imported |
Taxonomic identifieri | 2498135 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Streptosporangiales › Nocardiopsaceae › Streptomonospora › unclassified Streptomonospora |
Proteomesi |
|
Interactioni
Subunit structurei
Homodimer.
UniRule annotationFamily & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 29 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 43 – 46 | Substrate bindingUniRule annotation | 4 | |
Regioni | 87 – 89 | Substrate bindingUniRule annotation | 3 | |
Regioni | 216 – 218 | Substrate bindingUniRule annotation | 3 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 16 | PolarSequence analysisAdd BLAST | 16 |
Sequence similaritiesi
Belongs to the UPP synthase family.UniRule annotation
Family and domain databases
CDDi | cd00475, Cis_IPPS, 1 hit |
Gene3Di | 3.40.1180.10, 1 hit |
HAMAPi | MF_01139, ISPT, 1 hit |
InterProi | View protein in InterPro IPR001441, UPP_synth-like IPR018520, UPP_synth-like_CS IPR036424, UPP_synth-like_sf |
PANTHERi | PTHR10291, PTHR10291, 1 hit |
Pfami | View protein in Pfam PF01255, Prenyltransf, 1 hit |
SUPFAMi | SSF64005, SSF64005, 1 hit |
TIGRFAMsi | TIGR00055, uppS, 1 hit |
PROSITEi | View protein in PROSITE PS01066, UPP_SYNTHASE, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A4P6PYL7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLFNTSSTA SANRPPNPHP SGARPPELPK ELIPQHVAIV MDGNGRWAKE
60 70 80 90 100
RGLARTEGHR AGESSLFDVV EGALELGVGH LSAYAFSTEN WKRSPDEVRF
110 120 130 140 150
LMGFNREVIR RRRDELHAMG VRVRWAGRRG RLWKSVISEL EDAEEMTKHN
160 170 180 190 200
TALTLQFCVN YGGRAEIADA AAALARKAAE GRLNPDRITE AMLAKHLDEP
210 220 230 240 250
DIPDVDLFLR SSGEQRTSNF LLWQSAYAEM VFLDTLWPDF DRRHFWHACQ
260 270
VYASRDRRYG GAVPNPVEPR PTTTEEAR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP036455 Genomic DNA Translation: QBI53328.1 |
Genome annotation databases
KEGGi | strr:EKD16_07660 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP036455 Genomic DNA Translation: QBI53328.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
KEGGi | strr:EKD16_07660 |
Family and domain databases
CDDi | cd00475, Cis_IPPS, 1 hit |
Gene3Di | 3.40.1180.10, 1 hit |
HAMAPi | MF_01139, ISPT, 1 hit |
InterProi | View protein in InterPro IPR001441, UPP_synth-like IPR018520, UPP_synth-like_CS IPR036424, UPP_synth-like_sf |
PANTHERi | PTHR10291, PTHR10291, 1 hit |
Pfami | View protein in Pfam PF01255, Prenyltransf, 1 hit |
SUPFAMi | SSF64005, SSF64005, 1 hit |
TIGRFAMsi | TIGR00055, uppS, 1 hit |
PROSITEi | View protein in PROSITE PS01066, UPP_SYNTHASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A4P6PYL7_9ACTN | |
Accessioni | A0A4P6PYL7Primary (citable) accession number: A0A4P6PYL7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 31, 2019 |
Last sequence update: | July 31, 2019 | |
Last modified: | December 2, 2020 | |
This is version 11 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |