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Entry version 6 (10 Feb 2021)
Sequence version 1 (03 Jul 2019)
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Protein
Submitted name:

Protein kinase pkn/prk1 effector

Gene
N/A
Organism
Ixodes scapularis (Black-legged tick) (Deer tick)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinaseImported, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Protein kinase pkn/prk1 effectorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiIxodes scapularis (Black-legged tick) (Deer tick)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6945 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariParasitiformesIxodidaIxodoideaIxodidaeIxodinaeIxodes

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
VectorBase:ISCI001197
VectorBase:ISCW001197

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini197 – 454PL48InterPro annotationAdd BLAST258

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni110 – 188DisorderedSequence analysisAdd BLAST79
Regioni468 – 487DisorderedSequence analysisAdd BLAST20
Regioni499 – 537DisorderedSequence analysisAdd BLAST39
Regioni678 – 732DisorderedSequence analysisAdd BLAST55

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili254 – 284Sequence analysisAdd BLAST31
Coiled coili632 – 652Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi156 – 181PolarSequence analysisAdd BLAST26
Compositional biasi499 – 515PolyampholyteSequence analysisAdd BLAST17
Compositional biasi718 – 732PolarSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RIPOR family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031780, FAM65_N
IPR026136, RIPOR3

The PANTHER Classification System

More...
PANTHERi
PTHR15829, PTHR15829, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15903, PL48, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A4D5RR59-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
DRRRGYHGTW IVAGSFLHTR SNGRPVGRSF SVVCVSRQSE KRRRRRCCWW
60 70 80 90 100
ILCVSVLRRD YYGSMTNGDA WMTSRVTTDI AGRSERAKET TLDRRWESVV
110 120 130 140 150
CVVSHNMSLS ERLRSRQSPD PPPGGVLSRS RSFAGMLGHR RTASAVGAAP
160 170 180 190 200
TPAFGTDGGS SLSSGGSSSS SSSTLSKGSV LGQHHSPHAP RRILQGISST
210 220 230 240 250
WSGKPPRSPR PARTLLIFNA VERGLRECVG LAQEDILSLR SSVDNLSLSS
260 270 280 290 300
SQQLKTAERY LKRLEFQLSK VEELREQYEV QQRMRDGVRS MAYAYVLSPG
310 320 330 340 350
CEKDNALHGV RSGYRECVDT LCVLEAHLEQ LMGTLQFQMK GIQGFARLCA
360 370 380 390 400
GDNFEISVKH GEQKWKSRGR VQKNGQQVWD NQQIIVKALL GEFLFIKAVE
410 420 430 440 450
VRGLGKNVLL GNKSCEIKEL FSSHSQLMTV NLNSSGSLKL NLIITWNPLH
460 470 480 490 500
GCLEDSVAAS KQSPPVLGVM SSPFTRRRGT SPFRGDTILE RTGSLAHELE
510 520 530 540 550
QSRDWRQHSK DWDGRWRLPP AQGSASAPGS ALTSPNEEFP RAAVGQTLLV
560 570 580 590 600
NPYLAGRAQS PTLRALESTT SQRWSNTACD SSSYSCGSSL DLAESGNNGT
610 620 630 640 650
GPPAAPASSP LRESVQGLSA CLEDIQGHYP ELHSLEQSIA ELDRMLRKRS
660 670 680 690 700
RQRRASTGSN ASISIESALG CFDFLDSEET ESSESSPVRQ TTPYRNREAK
710 720 730 740 750
KNGGTADSGV ASLRDRRSPD AGSSTPSPVM ASTGSDQLDC AIAVHCCYCI
760 770 780 790 800
RLVEGLGTFG PLRSRERTSL EKLQLQARVL RRLLSVARRF SEDRRPIYGS
810 820 830 840 850
QLIDEDEVGH LWAQMGSGDG LVTTVGRLRE PLAHLVHSCV SQAAFCDRVT
860 870 880 890 900
SLILYKMLDV TKLEADMLVT ALQFQSYFAD VGAVLIVDHI ERLEAELKVL
910 920 930 940 950
DSLSSRELPI VKRTLSALKN VKVSREVLFS VSQMLVSGDK HLEHLAEQYL
960 970 980 990 1000
KSAARLLSKA EVCGTLVEGL EAEAALTRQG CCKGLSLLQA HEYMEELVHL
1010 1020 1030 1040
SYADEVAKVR QQAKEALFSF GEDGRREFQQ SQLVVHGFQG LTVK
Length:1,044
Mass (Da):114,925
Last modified:July 3, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA2D5A4E6F130CED
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei1044Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GHJT01005769 Transcribed RNA Translation: MOY39740.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GHJT01005769 Transcribed RNA Translation: MOY39740.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Organism-specific databases

VEuPathDBiVectorBase:ISCI001197
VectorBase:ISCW001197

Family and domain databases

InterProiView protein in InterPro
IPR031780, FAM65_N
IPR026136, RIPOR3
PANTHERiPTHR15829, PTHR15829, 1 hit
PfamiView protein in Pfam
PF15903, PL48, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A4D5RR59_IXOSC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A4D5RR59
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 3, 2019
Last sequence update: July 3, 2019
Last modified: February 10, 2021
This is version 6 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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