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UniProtKB - A0A494C1D7 (A0A494C1D7_HUMAN)

Entry version 17 (25 May 2022)
Sequence version 1 (05 Jun 2019)
Previous versions | rss
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Protein
Submitted name:

Dystonin

Gene

DST

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Dystonin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DST
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:1090, DST

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000151914

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

CytoplasmARBA annotation

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000151914

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...PeptideAtlasi		A0A494C1D7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A0A494C1D7, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A0A494C1D7

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini267 – 371Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini1003 – 1060SH3InterPro annotationAdd BLAST58

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni11 – 85DisorderedSequence analysisAdd BLAST75
Regioni116 – 143DisorderedSequence analysisAdd BLAST28
Regioni194 – 215DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili575 – 595Sequence analysisAdd BLAST21
Coiled coili793 – 813Sequence analysisAdd BLAST21
Coiled coili850 – 884Sequence analysisAdd BLAST35
Coiled coili956 – 979Sequence analysisAdd BLAST24
Coiled coili1225 – 1245Sequence analysisAdd BLAST21
Coiled coili1324 – 1358Sequence analysisAdd BLAST35
Coiled coili1534 – 1564Sequence analysisAdd BLAST31
Coiled coili1620 – 1647Sequence analysisAdd BLAST28
Coiled coili1709 – 1729Sequence analysisAdd BLAST21
Coiled coili1753 – 1787Sequence analysisAdd BLAST35
Coiled coili1873 – 1893Sequence analysisAdd BLAST21
Coiled coili1920 – 1940Sequence analysisAdd BLAST21
Coiled coili1969 – 1996Sequence analysisAdd BLAST28
Coiled coili2284 – 2304Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi57 – 85Polar residuesSequence analysisAdd BLAST29
Compositional biasi116 – 131Polar residuesSequence analysisAdd BLAST16

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155008

Family and domain databases

Conserved Domains Database

More...CDDi		cd00014, CH, 1 hit
cd00176, SPEC, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.418.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

The PANTHER Classification System

More...PANTHERi		PTHR23169, PTHR23169, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00307, CH, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 4 hits
PF18373, Spectrin_like, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00033, CH, 1 hit
SM00150, SPEC, 7 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50021, CH, 1 hit
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

A0A494C1D7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNVCGCVRA EKEEQYVDPA KTPLNPEKYS PGRKYFRRKP IKKTGGDKES 
        60         70         80         90        100
VGANNENEGK KKSSSQPSKE QPAPLSRGLV QQESVTLNSA LGDGIQQKKT 
       110        120        130        140        150
EVVADSVKQK LLPSAVSSWS DCVNTSPAKD SETEVKVSEL DERISEKDST 
       160        170        180        190        200
PYCAKRKKHL DDVNTSEITF QEKTDVFSFR KAASLSSIPS GIERSLEKSG 
       210        220        230        240        250
FPEDPPKSYS SIQEKQNTER FCPHATQHFQ FKKKRCHSLY TSMSSVSKDT 
       260        270        280        290        300
DGNEISDIHV TGESEDMSAK ERLLLWTQQA TEGYAGIRCE NFTTCWRDGK 
       310        320        330        340        350
LFNAIIHKYR PDLIDMNTVA VQSNLANLEH AFYVAEKIGV IRLLDPEDVD 
       360        370        380        390        400
VSSPDEKSVI TYVSSLYDAF PKVPEGGEGI GANDVEVKWI EYQNMVNYLI 
       410        420        430        440        450
QWIRHHVTTM SERTFPNNPV ELKALYNQYL QFKETEIPPK ETEKSKIKRL 
       460        470        480        490        500
YKLLEIWIEF GRIKLLQGYH PNDIEKEWGK LIIAMLEREK ALRPEVERLE 
       510        520        530        540        550
MLQQIANRVQ RDSVICEDKL ILAGNALQSD SKRLESGVQF QNEAEIAGYI 
       560        570        580        590        600
LECENLLRQH VIDVQILIDG KYYQADQLVQ RVAKLRDEIM ALRNECSSVY 
       610        620        630        640        650
SKGRILTTEQ TKLMISGITQ SLNSGFAQTL HPSLTSGLTQ SLTPSLTSSS 
       660        670        680        690        700
MTSGLSSGMT SRLTPSVTPA YTPGFPSGLV PNFSSGVEPN SLQTLKLMQI 
       710        720        730        740        750
RKPLLKSSLL DQNLTEEEIN MKFVQDLLNW VDEMQVQLDR TEWGSDLPSV 
       760        770        780        790        800
ESHLENHKNV HRAIEEFESS LKEAKISEIQ MTAPLKLTYA EKLHRLESQY 
       810        820        830        840        850
AKLLNTSRNQ ERHLDTLHNF VSRATNELIW LNEKEEEEVA YDWSERNTNI 
       860        870        880        890        900
ARKKDYHAEL MRELDQKEEN IKSVQEIAEQ LLLENHPARL TIEAYRAAMQ 
       910        920        930        940        950
TQWSWILQLC QCVEQHIKEN TAYFEFFNDA KEATDYLRNL KDAIQRKYSC 
       960        970        980        990       1000
DRSSSIHKLE DLVQESMEEK EELLQYKSTI ANLMGKAKTI IQLKPRNSDC 
      1010       1020       1030       1040       1050
PLKTSIPIKA ICDYRQIEIT IYKDDECVLA NNSHRAKWKV ISPTGNEAMV 
      1060       1070       1080       1090       1100
PSVCFTVPPP NKEAVDLANR IEQQYQNVLT LWHESHINMK SVVSWHYLIN 
      1110       1120       1130       1140       1150
EIDRIRASNV ASIKTMLPGE HQQVLSNLQS RFEDFLEDSQ ESQVFSGSDI 
      1160       1170       1180       1190       1200
TQLEKEVNVC KQYYQELLKS AEREEQEESV YNLYISEVRN IRLRLENCED 
      1210       1220       1230       1240       1250
RLIRQIRTPL ERDDLHESVF RITEQEKLKK ELERLKDDLG TITNKCEEFF 
      1260       1270       1280       1290       1300
SQAAASSSVP TLRSELNVVL QNMNQVYSMS STYIDKLKTV NLVLKNTQAA 
      1310       1320       1330       1340       1350
EALVKLYETK LCEEEAVIAD KNNIENLIST LKQWRSEVDE KRQVFHALED 
      1360       1370       1380       1390       1400
ELQKAKAISD EMFKTYKERD LDFDWHKEKA DQLVERWQNV HVQIDNRLRD 
      1410       1420       1430       1440       1450
LEGIGKSLKY YRDTYHPLDD WIQQVETTQR KIQENQPENS KTLATQLNQQ 
      1460       1470       1480       1490       1500
KMLVSEIEMK QSKMDECQKY AEQYSATVKD YELQTMTYRA MVDSQQKSPV 
      1510       1520       1530       1540       1550
KRRRMQSSAD LIIQEFMDLR TRYTALVTLM TQYIKFAGDS LKRLEEEEKS 
      1560       1570       1580       1590       1600
LEEEKKEHVE KAKELQKWVS NISKTLKDAE KAGKPPFSKQ KISSEEISTK 
      1610       1620       1630       1640       1650
KEQLSEALQT IQLFLAKHGD KMTDEERNEL EKQVKTLQES YNLLFSESLK 
      1660       1670       1680       1690       1700
QLQESQTSGD VKVEEKIVAE RQQEYKEKLQ GICDLLTQTE NRLIGHQEAF 
      1710       1720       1730       1740       1750
MIGDGTVELK KYQSKQEELQ KDMQGSAQAL AEVVKNTENF LKENGEKLSQ 
      1760       1770       1780       1790       1800
EDKALIEQKL NEAKIKCEQL NLKAEQSKKE LDKVVTTAIK EETEKVAAVK 
      1810       1820       1830       1840       1850
QLEESKTKIE NLLDWLSNVD KDSERAGTKH KQVIEQNGTH FQEGDGKSAI 
      1860       1870       1880       1890       1900
GEEDEVNGNL LETDVDGQVG TTQENLNQQY QKVKAQHEKI ISQHQAVIIA 
      1910       1920       1930       1940       1950
TQSAQVLLEK QGQYLSPEEK EKLQKNMKEL KVHYETALAE SEKKMKLTHS 
      1960       1970       1980       1990       2000
LQEELEKFDA DYTEFEHWLQ QSEQELENLE AGADDINGLM TKLKRQKSFS 
      2010       2020       2030       2040       2050
EDVISHKGDL RYITISGNRV LEAAKSCSKR DGGKVDTSAT HREVQRKLDH 
      2060       2070       2080       2090       2100
ATDRFRSLYS KCNVLGNNLK DLVDKYQHYE DASCGLLAGL QACEATASKH 
      2110       2120       2130       2140       2150
LSEPIAVDPK NLQRQLEETK ALQGQISSQQ VAVEKLKKTA EVLLDARGSL 
      2160       2170       2180       2190       2200
LPAKNDIQKT LDDIVGRYED LSKSVNERNE KLQITLTRSL SVQDGLDEML 
      2210       2220       2230       2240       2250
DWMGNVESSL KEQGQVPLNS TALQDIISKN IMLEQDIAGR QSSINAMNEK 
      2260       2270       2280       2290       2300
VKKFMETTDP STASSLQAKM KDLSARFSEA SHKHKETLAK MEELKTKVEL 
      2310       2320       2330       2340       2350
FENLSEKLQT FLETKTQALT EVDVPGKDVT ELSQYMQEST SEFLEHKKHL 
      2360       2370       2380 
EVLHSLLKEI SSHGLPSDKA LVLEKTNNLS KKF
Length:2,383
Mass (Da):273,039
Last modified:June 5, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF470423A58B40530
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q03001DYST_HUMAN
Dystonin
DST BP230, BP240, BPAG1, DMH, DT
7,570Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8W9J4F8W9J4_HUMAN
Dystonin
DST
7,461Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PHM6E9PHM6_HUMAN
Dystonin
DST
5,497Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6QMI7F6QMI7_HUMAN
Dystonin
DST
5,537Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7P0T890A0A7P0T890_HUMAN
Dystonin
DST
7,818Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0U1RQJ2A0A0U1RQJ2_HUMAN
Dystonin
DST
2,676Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C073A0A494C073_HUMAN
Dystonin
DST
1,347Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A494C1U5A0A494C1U5_HUMAN
Dystonin
DST
625Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T0V7Q5T0V7_HUMAN
Dystonin
DST
689Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q6P0N6Q6P0N6_HUMAN
DST protein
DST
1,143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei23831

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000652573.1; ENSP00000498983.1; ENSG00000151914.22

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL096710 Genomic DNA No translation available.
AL137008 Genomic DNA No translation available.
AL512422 Genomic DNA No translation available.
AL512448 Genomic DNA No translation available.
AL590005 Genomic DNA No translation available.
AL590037 Genomic DNA No translation available.
KF458172 Genomic DNA No translation available.

3D structure databases

SMRiA0A494C1D7
ModBaseiSearch...

Proteomic databases

PeptideAtlasiA0A494C1D7

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		31066, 184 antibodies from 22 providers

Genome annotation databases

EnsembliENST00000652573.1; ENSP00000498983.1; ENSG00000151914.22

Organism-specific databases

HGNCiHGNC:1090, DST
OpenTargetsiENSG00000151914
VEuPathDBiHostDB:ENSG00000151914

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00940000155008

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DST, human

Gene expression databases

ExpressionAtlasiA0A494C1D7, baseline and differential

Family and domain databases

CDDicd00014, CH, 1 hit
cd00176, SPEC, 3 hits
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR041615, Desmoplakin_SH3
IPR041573, Desmoplakin_Spectrin-like
IPR043197, Plakin
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PANTHERiPTHR23169, PTHR23169, 2 hits
PfamiView protein in Pfam
PF00307, CH, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 4 hits
PF18373, Spectrin_like, 1 hit
SMARTiView protein in SMART
SM00033, CH, 1 hit
SM00150, SPEC, 7 hits
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS50021, CH, 1 hit
PS50002, SH3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A494C1D7_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A494C1D7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 5, 2019
Last sequence update: June 5, 2019
Last modified: May 25, 2022
This is version 17 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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