UniProtKB - A0A494BB27 (A0A494BB27_MOUSE)
Protein
Submitted name:
Homeobox protein PKNOX1
Gene
Pknox1
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 147 – 209 | HomeoboxPROSITE-ProRule annotationAdd BLAST | 63 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-UniRule
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Homeobox protein PKNOX1Imported |
Gene namesi | Name:Pknox1Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1201409, Pknox1 |
Subcellular locationi
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 145 – 208 | HomeoboxInterPro annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 289 – 324 | DisorderedSequence analysisAdd BLAST | 36 |
Sequence similaritiesi
Belongs to the TALE/MEIS homeobox family.ARBA annotation
Keywords - Domaini
HomeoboxPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000159505 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR008422, Homeobox_KN_domain IPR032453, PKNOX/Meis_N |
Pfami | View protein in Pfam PF05920, Homeobox_KN, 1 hit PF16493, Meis_PKNOX_N, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS50071, HOMEOBOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
A0A494BB27-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MWRWSQMVKA IQVLRIHLLE LEKVNELCKD FCSRYIACLK TKMNSETLLS
60 70 80 90 100
GEPGSPYSPV QSQIQSAITG TLSPQGIVVP ASALQQGNVT MATVAGGTVY
110 120 130 140 150
QPVTVVTPQG QVVTQALSPG TIRIQNSQLQ LQLNQDLSIL HQEDGSSKNK
160 170 180 190 200
RGVLPKHATN VMRSWLFQHI GHPYPTEDEK KQIAAQTNLT LLQVNNWFIN
210 220 230 240 250
ARRRILQPML DSSCSETPKT KKKPAQNRPV QRFWPDSLAS GVAQATPSEL
260 270 280 290 300
AMSEGAVVTI TTPVNMNVDS LQSLSSDGAT LAVQQVMMAG QSEDESVDST
310 320
EDEGGALAPT HISGLVLENS DSLQ
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketO70477 | PKNX1_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 436 | Annotation score: | ||
A0A494B9U0 | A0A494B9U0_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 435 | Annotation score: | ||
A0A494B958 | A0A494B958_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 325 | Annotation score: | ||
A0A494BA52 | A0A494BA52_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 323 | Annotation score: | ||
A0A494B934 | A0A494B934_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 61 | Annotation score: | ||
A0A494BAI2 | A0A494BAI2_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 41 | Annotation score: | ||
A0A494B900 | A0A494B900_MOUSE | Homeobox protein PKNOX1 | Pknox1 | 19 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC166172 Genomic DNA No translation available. AC166575 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000237748; ENSMUSP00000158343; ENSMUSG00000006705 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC166172 Genomic DNA No translation available. AC166575 Genomic DNA No translation available. |
3D structure databases
SMRi | A0A494BB27 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 3800, 230 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000237748; ENSMUSP00000158343; ENSMUSG00000006705 |
Organism-specific databases
MGIi | MGI:1201409, Pknox1 |
Phylogenomic databases
GeneTreei | ENSGT00940000159505 |
Miscellaneous databases
ChiTaRSi | Pknox1, mouse |
SOURCEi | Search... |
Gene expression databases
ExpressionAtlasi | A0A494BB27, baseline and differential |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR009057, Homeobox-like_sf IPR001356, Homeobox_dom IPR008422, Homeobox_KN_domain IPR032453, PKNOX/Meis_N |
Pfami | View protein in Pfam PF05920, Homeobox_KN, 1 hit PF16493, Meis_PKNOX_N, 1 hit |
SMARTi | View protein in SMART SM00389, HOX, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS50071, HOMEOBOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A494BB27_MOUSE | |
Accessioni | A0A494BB27Primary (citable) accession number: A0A494BB27 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 5, 2019 |
Last sequence update: | June 5, 2019 | |
Last modified: | August 12, 2020 | |
This is version 10 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |