UniProtKB - A0A494BA69 (A0A494BA69_MOUSE)
Protein
Submitted name:
Cathepsin W
Gene
Ctsw
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Cathepsin WImported |
Gene namesi | Name:CtswImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1338045, Ctsw |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 21 | Sequence analysisAdd BLAST | 21 | |
ChainiPRO_5019790350 | 22 – 342 | Sequence analysisAdd BLAST | 321 |
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 40 – 97 | Inhibitor_I29InterPro annotationAdd BLAST | 58 | |
Domaini | 106 – 328 | Pept_C1InterPro annotationAdd BLAST | 223 |
Sequence similaritiesi
Belongs to the peptidase C1 family.ARBA annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000161630 |
OMAi | TCGITKY |
Family and domain databases
CDDi | cd02248, Peptidase_C1A, 1 hit |
InterProi | View protein in InterPro IPR033158, Cathepsin_W IPR038765, Papain-like_cys_pep_sf IPR025661, Pept_asp_AS IPR025660, Pept_his_AS IPR000668, Peptidase_C1A_C IPR039417, Peptidase_C1A_papain-like IPR013201, Prot_inhib_I29 |
PANTHERi | PTHR12411:SF101, PTHR12411:SF101, 2 hits |
Pfami | View protein in Pfam PF08246, Inhibitor_I29, 1 hit PF00112, Peptidase_C1, 1 hit |
PRINTSi | PR00705, PAPAIN |
SMARTi | View protein in SMART SM00848, Inhibitor_I29, 1 hit SM00645, Pept_C1, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS00640, THIOL_PROTEASE_ASN, 1 hit PS00639, THIOL_PROTEASE_HIS, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
A0A494BA69-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTLTAHLSYF LVLLLAGQGL SDSLLTKDAG PRPLELKEVF KLFQIRFNRS
60 70 80 90 100
YWNPAEYTRR LSIFAHNLAQ AQRLQQEDLG TAEFGETPFS DLTEEEFGQL
110 120 130 140 150
YGQERSPERT PNMTKKGSCK CCWAMAAADN IQALWRIKHQ QFVDVSVQEL
160 170 180 190 200
LDCERCGNGC NGGFVWDAYL TVLNNSGLAS EKDYPFQGDR KPHRCLAKKY
210 220 230 240 250
KKVAWIQDFT MLSNNEQAIA HYLAVHGPIT VTINMKLLQH YQKGVIKATP
260 270 280 290 300
SSCDPRQVDH SVLLVGFGKE KEGMQTGTVL SHSRKRRHSS PYWILKNSWG
310 320 330 340
AHWGEKGYFR LYRGNNTCGV TKYPFTAQVD SPVKKARTSC PP
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP56203 | CATW_MOUSE | Cathepsin W | Ctsw | 371 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC122861 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000236256; ENSMUSP00000157959; ENSMUSG00000024910 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC122861 Genomic DNA No translation available. |
3D structure databases
SMRi | A0A494BA69 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 4281, 100 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000236256; ENSMUSP00000157959; ENSMUSG00000024910 |
Organism-specific databases
MGIi | MGI:1338045, Ctsw |
Phylogenomic databases
GeneTreei | ENSGT00940000161630 |
OMAi | TCGITKY |
Miscellaneous databases
ChiTaRSi | Ctsw, mouse |
SOURCEi | Search... |
Gene expression databases
ExpressionAtlasi | A0A494BA69, baseline and differential |
Family and domain databases
CDDi | cd02248, Peptidase_C1A, 1 hit |
InterProi | View protein in InterPro IPR033158, Cathepsin_W IPR038765, Papain-like_cys_pep_sf IPR025661, Pept_asp_AS IPR025660, Pept_his_AS IPR000668, Peptidase_C1A_C IPR039417, Peptidase_C1A_papain-like IPR013201, Prot_inhib_I29 |
PANTHERi | PTHR12411:SF101, PTHR12411:SF101, 2 hits |
Pfami | View protein in Pfam PF08246, Inhibitor_I29, 1 hit PF00112, Peptidase_C1, 1 hit |
PRINTSi | PR00705, PAPAIN |
SMARTi | View protein in SMART SM00848, Inhibitor_I29, 1 hit SM00645, Pept_C1, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS00640, THIOL_PROTEASE_ASN, 1 hit PS00639, THIOL_PROTEASE_HIS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A494BA69_MOUSE | |
Accessioni | A0A494BA69Primary (citable) accession number: A0A494BA69 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 5, 2019 |
Last sequence update: | June 5, 2019 | |
Last modified: | April 7, 2021 | |
This is version 11 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |