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UniProtKB - A0A494B9H2 (A0A494B9H2_MOUSE)
Protein
Submitted name:
Glucose-6-phosphate exchanger SLC37A1
Gene
Slc37a1
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Glucose-6-phosphate exchanger SLC37A1Imported |
Gene namesi | Name:Slc37a1Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2446181, Slc37a1 |
VEuPathDBi | HostDB:ENSMUSG00000024036 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 19 – 37 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 98 – 116 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 128 – 150 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 156 – 184 | HelicalSequence analysisAdd BLAST | 29 | |
Transmembranei | 196 – 215 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 221 – 242 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 285 – 306 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 326 – 343 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 350 – 367 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 379 – 402 | HelicalSequence analysisAdd BLAST | 24 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 27 – 430 | MFSInterPro annotationAdd BLAST | 404 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 53 – 72 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family. [View classification]ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000159245 |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR000849, Sugar_P_transporter |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
PIRSFi | PIRSF002808, Hexose_phosphate_transp, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All
A0A494B9H2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALLPVGIRF IISFSRDQWY RAFIFMLTFL LYASFHLSRK PISIVKGELH
60 70 80 90 100
KQCTAGDGPE SPFSDPSSST RHGPTHWLLN NETDCGWAPF DKNNYQQLLG
110 120 130 140 150
ALDYAFLCAY AIGMYLSGII GERLPIRYYL TFGMLASGAF TALFGLGYFY
160 170 180 190 200
NIHSLGFYVV TQIINGLVQT TGWPSVVTCL SNWFGKGRRG LIMGIWNSHT
210 220 230 240 250
SVGNILGSLI AGYWVSTCWG LSFIVPGAIV AAMGIVCFLF LIEHPKDVKC
260 270 280 290 300
SSTLPTHPRA SENGINRFRL QKQTTYSEKN GPLGVIEFSL CLLFAKLVSY
310 320 330 340 350
TFLFWLPLYI TSVDHLDAKK AGELSTLFDV GGIFGGILAG VISDRLEKRA
360 370 380 390 400
STCGLMLLLA APTLYVFSSV SRMGLEATIA MLLLSGALVS GPYALITTAV
410 420 430
SADLGTHKSL KGNSHALSTV TAIIDGTGSV
Computationally mapped potential isoform sequencesi
There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8R070 | G6PT2_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 531 | Annotation score: | ||
A0A494BBG7 | A0A494BBG7_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 359 | Annotation score: | ||
A0A494B938 | A0A494B938_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 83 | Annotation score: | ||
A0A494BBH2 | A0A494BBH2_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 87 | Annotation score: | ||
A0A494BAD1 | A0A494BAD1_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 108 | Annotation score: | ||
A0A494B9S8 | A0A494B9S8_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 18 | Annotation score: | ||
A0A494B977 | A0A494B977_MOUSE | Glucose-6-phosphate exchanger SLC37... | Slc37a1 | 51 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 430 | Imported | 1 |
Genome annotation databases
Ensembli | ENSMUST00000236251; ENSMUSP00000157617; ENSMUSG00000024036 |
Similar proteinsi
Cross-referencesi
3D structure databases
SMRi | A0A494B9H2 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 23842, 82 antibodies from 19 providers |
Genome annotation databases
Ensembli | ENSMUST00000236251; ENSMUSP00000157617; ENSMUSG00000024036 |
Organism-specific databases
MGIi | MGI:2446181, Slc37a1 |
VEuPathDBi | HostDB:ENSMUSG00000024036 |
Phylogenomic databases
GeneTreei | ENSGT00940000159245 |
Miscellaneous databases
ChiTaRSi | Slc37a2, mouse |
SOURCEi | Search... |
Gene expression databases
ExpressionAtlasi | A0A494B9H2, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf IPR000849, Sugar_P_transporter |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
PIRSFi | PIRSF002808, Hexose_phosphate_transp, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A494B9H2_MOUSE | |
Accessioni | A0A494B9H2Primary (citable) accession number: A0A494B9H2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 5, 2019 |
Last sequence update: | June 5, 2019 | |
Last modified: | January 19, 2022 | |
This is version 13 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |