Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 5 (11 Dec 2019)
Sequence version 1 (05 Jun 2019)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Nebulin-related-anchoring protein

Gene

LYPA_23C014947

Organism
Lynx pardinus (Iberian lynx) (Felis pardina)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nebulin-related-anchoring proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LYPA_23C014947Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLynx pardinus (Iberian lynx) (Felis pardina)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri191816 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeLynx

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 64LIM zinc-bindingInterPro annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1696 – 1719DisorderedSequence analysisAdd BLAST24

Keywords - Domaini

LIM domainPROSITE-ProRule annotationSAAS annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013998 Nebulin-like
IPR000900 Nebulin_repeat
IPR001781 Znf_LIM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00412 LIM, 1 hit
PF00880 Nebulin, 14 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00510 NEBULIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00132 LIM, 1 hit
SM00227 NEBU, 42 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00478 LIM_DOMAIN_1, 1 hit
PS50023 LIM_DOMAIN_2, 1 hit
PS51216 NEBULIN, 43 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A485N2X0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNVQACSRCG YGVYPAEKIS CLDQIWHKAC FHCEVCKMML SVNNFVSHQK
60 70 80 90 100
KPYCHAHNPK NNTFTSVYHT PLNLNMRKTP EAIHGVDDQD DSERFKSVFH
110 120 130 140 150
WDMKSRDGAD AANRQPLVNE VREERGYWTG YGEGSGWCPG ALPDPEIVRM
160 170 180 190 200
VEARKSLGEQ EYTEDYEQQR GKGSFPAMIT PAYQRAKKAN QLASQVEYKR
210 220 230 240 250
GHDERISTFS TVADTPELLR AKAGGQLQSD VRYTEDYEQQ RGKGSFPAMI
260 270 280 290 300
TPAYQIAKRA NELASDVRYH QQYQREMKGV ARPAAGAAGA SSRECMDQYG
310 320 330 340 350
QGYLEEYEEH RGKGSFPAMI TPAYQNAKKA NELASDIKYR QDFNKMKGPA
360 370 380 390 400
HYHSLPAQDN LVLKRAQSVN KLVSEVEYKK DLESSKGHSI NYCETPQFRN
410 420 430 440 450
VSKISKFTSD NKYKENYQNH MRGHYEGVGM DRRTLHAMKV GSLASNVAYK
460 470 480 490 500
ADYKHDVVDY NYPATLTPSY QTTVRLVPLK DVNYRQSIDK LKYSSVTNTP
510 520 530 540 550
QIVQAKINAQ QLSHVNYRAD YEKNKLNYTL PQDIPQLVKA RTNAELFSEV
560 570 580 590 600
KYREGWDKAK GKGFELKLDA MSLLAAKASG ELASNIKYKE EYEKSKGKVM
610 620 630 640 650
GTTDTRLLHS LQVAKMSSEV EYKKGFEESK TRFHLPMDMV HIKHAKKAQA
660 670 680 690 700
LASDLDYRKK LHEYTVLPED MKTQWAKKAY GLQSELQYKA DLAWMKGVGW
710 720 730 740 750
LTEGSLNLEQ AKKAGQLISE KNYRQRADGL KFTSVTDSSQ MAHARKSQEL
760 770 780 790 800
QSGVAYKAGN EQSVHQYSIS KDEPLFLQAR ANAANLSEKL YKSSWENQKA
810 820 830 840 850
KGFELRLDSL AFLAAKANRD LASEVKYKED YERSRGKLIG AKDAQGDSQM
860 870 880 890 900
SHSLQMSKLQ SDLEYKKGFE DTRSQCHVSL DMVHLVHARK AQHLATDIGY
910 920 930 940 950
KTASHHFTAL PTDMRVEWAK KAYGLQSDNQ YRADVKWMKG TGWVATGSLN
960 970 980 990 1000
VEQAKKAGEL ISEKKYRQPP DALKFTSIKD TPEMVQARIS YTQAVDRLYK
1010 1020 1030 1040 1050
EQGENIKHHY TQTADLPEVL LAKLNAMNIS ETRYKESWSK LRDGGYKLRL
1060 1070 1080 1090 1100
DAIPFQAAKA SGEIISDYKY KEAFEKMKGQ MLGSRSLEDD ISLAHSVYAN
1110 1120 1130 1140 1150
SLQSEVNYKK GFELSKAHFH LPLDMVTLVH ARKAQSLASD QDYRHPLPQY
1160 1170 1180 1190 1200
TSLAEDLRLS CAKRAHKLQS ENLYRSDLNF MRGVPCVIPG TLEIEGRKKA
1210 1220 1230 1240 1250
SELISESKYR QHPQSFKYTA VTDTPSLLHA KLSNQITNER LYKAAGDEER
1260 1270 1280 1290 1300
HRYTMTLGLP EFARAKANAA NLSDAKYKES WRNLRAQGYK LTIDALPFQA
1310 1320 1330 1340 1350
ARVSGDIASD FLYRHDFVKE RGRLIGTRSV SEDPRLRHCW RVGQLQSELQ
1360 1370 1380 1390 1400
YRRGAAGSRA QCHLPMDMVH LVHARKAQAL ASDHDYRTWC HEFTALPEDL
1410 1420 1430 1440 1450
KMSWAKRAHA LQSEFRYKSD LMGMKGTGWL TLSSPQLECA KKAGELISET
1460 1470 1480 1490 1500
KYRKKPDSIK FTTVVDSPDL VHAKNSYLHC NERLYRAGDA ESLHRYTPIP
1510 1520 1530 1540 1550
DHPDFTRARL NAQCLSDKAY RNSWEQTRAV GYDFRLEAIP FQTARASREI
1560 1570 1580 1590 1600
ASDFRYKEAF LRDRGQQIGY RSVQDDPRMR HFLNVGKLQS DNEYKKDFAK
1610 1620 1630 1640 1650
SRSQFHSRPD QPGLLQARRS QQLASDVCYR QPLPQPTCDP EQLGLKHAQK
1660 1670 1680 1690 1700
AHQLQSDVKY KSDLNLTRGI GWTPPGSYKV EMARRAAELA KARGLGLRGA
1710 1720 1730
DGGPEAVEPA DNQRGDVNPD AMEILHVKRR RGLPL
Length:1,735
Mass (Da):197,569
Last modified:June 5, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0A736026560AC4FB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CAAGRJ010010356 Genomic DNA Translation: VFV27750.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAGRJ010010356 Genomic DNA Translation: VFV27750.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR013998 Nebulin-like
IPR000900 Nebulin_repeat
IPR001781 Znf_LIM
PfamiView protein in Pfam
PF00412 LIM, 1 hit
PF00880 Nebulin, 14 hits
PRINTSiPR00510 NEBULIN
SMARTiView protein in SMART
SM00132 LIM, 1 hit
SM00227 NEBU, 42 hits
PROSITEiView protein in PROSITE
PS00478 LIM_DOMAIN_1, 1 hit
PS50023 LIM_DOMAIN_2, 1 hit
PS51216 NEBULIN, 43 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A485N2X0_LYNPA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A485N2X0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 5, 2019
Last sequence update: June 5, 2019
Last modified: December 11, 2019
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again