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Entry version 2 (03 Jul 2019)
Sequence version 1 (05 Jun 2019)
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Protein
Submitted name:

Fibronectin isoform X10

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Fibronectin isoform X10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi466 ↔ 492PROSITE-ProRule annotation
Disulfide bondi480 ↔ 507PROSITE-ProRule annotation
Disulfide bondi526 ↔ 552PROSITE-ProRule annotation
Disulfide bondi540 ↔ 567PROSITE-ProRule annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini155 – 195Fibronectin type-IInterPro annotationAdd BLAST41
Domaini200 – 243Fibronectin type-IInterPro annotationAdd BLAST44
Domaini244 – 287Fibronectin type-IInterPro annotationAdd BLAST44
Domaini289 – 334Fibronectin type-IInterPro annotationAdd BLAST46
Domaini335 – 379Fibronectin type-IInterPro annotationAdd BLAST45
Domaini412 – 451Fibronectin type-IInterPro annotationAdd BLAST40
Domaini461 – 509Fibronectin type-IIInterPro annotationAdd BLAST49
Domaini521 – 569Fibronectin type-IIInterPro annotationAdd BLAST49
Domaini574 – 617Fibronectin type-IInterPro annotationAdd BLAST44
Domaini622 – 664Fibronectin type-IInterPro annotationAdd BLAST43
Domaini665 – 708Fibronectin type-IInterPro annotationAdd BLAST44
Domaini716 – 811Fibronectin type-IIIInterPro annotationAdd BLAST96
Domaini828 – 918Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini919 – 1010Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini1015 – 1106Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini1107 – 1194Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini1195 – 1281Fibronectin type-IIIInterPro annotationAdd BLAST87
Domaini1282 – 1372Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini1375 – 1467Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini1468 – 1555Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini1556 – 1649Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini1650 – 1741Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini1742 – 1829Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini1830 – 1923Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini1924 – 2010Fibronectin type-IIIInterPro annotationAdd BLAST87
Domaini2011 – 2101Fibronectin type-IIIInterPro annotationAdd BLAST91
Domaini2209 – 2303Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini2310 – 2354Fibronectin type-IInterPro annotationAdd BLAST45
Domaini2355 – 2397Fibronectin type-IInterPro annotationAdd BLAST43
Domaini2399 – 2439Fibronectin type-IInterPro annotationAdd BLAST41

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 56DisorderedSequence analysisAdd BLAST56
Regioni128 – 152DisorderedSequence analysisAdd BLAST25
Regioni1498 – 1518DisorderedSequence analysisAdd BLAST21
Regioni1677 – 1699DisorderedSequence analysisAdd BLAST23
Regioni2164 – 2184DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi128 – 150PolarSequence analysisAdd BLAST23
Compositional biasi1498 – 1513PolyampholyteSequence analysisAdd BLAST16

Keywords - Domaini

RepeatSAAS annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00061 FN1, 12 hits
cd00062 FN2, 2 hits
cd00063 FN3, 15 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.10.10.10, 2 hits
2.60.40.10, 16 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000083 Fibronectin_type1
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR000562 FN_type2_dom
IPR036943 FN_type2_sf
IPR013783 Ig-like_fold
IPR013806 Kringle-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00039 fn1, 12 hits
PF00040 fn2, 2 hits
PF00041 fn3, 15 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00058 FN1, 12 hits
SM00059 FN2, 2 hits
SM00060 FN3, 16 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49265 SSF49265, 10 hits
SSF57440 SSF57440, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01253 FN1_1, 6 hits
PS51091 FN1_2, 12 hits
PS00023 FN2_1, 1 hit
PS51092 FN2_2, 2 hits
PS50853 FN3, 16 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A480EIV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRSHINPSS RVSAARAGCA LQGGRRGSPR RERGRGDLQP QLLSSSPSPL
60 70 80 90 100
SLYPSPSPSS SPYLLGGVGR SGHWKGLLWQ VAKKKSNLVE SCLLVRASIS
110 120 130 140 150
PHLLKMLGGP GPGLLLLAVL SLGTTVPSTG ASKSKRQAQQ IVQPQSPLVD
160 170 180 190 200
SQRKPGCYDN GKHYQINQQW ERTYLGSALV CTCYGGSRGF NCESKPEPEE
210 220 230 240 250
TCFDKYTGNT YRVGDTYERP KDSMIWDCTC IGAGRGRISC TIANRCHEGG
260 270 280 290 300
QSYKIGDTWR RPHETGGYML ECVCLGNGKG EWTCKPIAEK CFDHAAGGTS
310 320 330 340 350
YVVGETWEKP YQGWMMVDCT CLGEGSGRIT CTSRNRCNDQ DTRTSYRIGD
360 370 380 390 400
TWSKKDNRGN LLQCICTGNG RGEWKCERHT SLQTTSAGSG SFTDVRTAIY
410 420 430 440 450
QPQPHPQPAP YGHCVTDSGV VYSVGMQWLK TQGNKQMLCT CLGNGVSCQE
460 470 480 490 500
TAVTQTYGGN SNGEPCVLPF TYNGRTFYSC TTEGRQDGHL WCSTTSNYEQ
510 520 530 540 550
DQKYSFCTDH TVLVQTRGGN SNGALCHFPF LYNNRNYTDC TSEGRRDNMK
560 570 580 590 600
WCGTTQNYDA DQKFGFCPMA AHEEICTTNE GVMYRIGDQW DKQHDMGHMM
610 620 630 640 650
RCTCVGNGRG EWTCVAYSQL RDQCIVDDIT YNVNDTFHKR HEEGHMLNCT
660 670 680 690 700
CFGQGRGRWK CDPVDQCQDS ETRTFYQIGD SWEKYVHGVR YQCYCYGRGI
710 720 730 740 750
GEWHCQPLQT YPGTTGPVQV IITETPSQPN SHPIQWNAPE PSHISKYILR
760 770 780 790 800
WKPKNSPNRW KEATIPGHLN SYTIKGLRPG VVYEGQLISV QHYGHREVTR
810 820 830 840 850
FDFTTTSTSS AVTSNTVVGE TTPFSPVVAT SESVTEITAS SFVVSWVSAS
860 870 880 890 900
DTVSGFRVEY ELSEEGDEPQ YLDLPSTATS VNIPDLLPGR KYIVNVYQIS
910 920 930 940 950
EEGEQSLILS TSQTTAPDAP PDPTVDQVDD TSIVVRWSRP QAPITGYRIV
960 970 980 990 1000
YSPSVEGSST ELNLPETANS VTLSDLQPGV QYNITIYAVE ENQESTPVFI
1010 1020 1030 1040 1050
QQETTGVPRP DKVPPPKDLQ FVEVTDVKVT IMWTPPESPV TGYRVDVIPV
1060 1070 1080 1090 1100
NLPGEHGQRL PISRNTFAEV TGLSPGVTYH FKVFAVNQGR ESKPLTAQQT
1110 1120 1130 1140 1150
TKLDAPTNLQ FINETDSTVM VTWTPPRARI AGYRLTVGLT RGGQPKQYNV
1160 1170 1180 1190 1200
GPSASQYLLR NLQPGSEYAV TLVAVKGNQQ SPRATGVFTT LQPVGSIPPY
1210 1220 1230 1240 1250
NTEVTETTIV ITWTPAPRIG FKLGVRPSQG GEAPREVTSD SGSIVVSGLT
1260 1270 1280 1290 1300
PGVEYVYTIS VLRDGQERDT PIVKKVVTPL SPPTNLHLEA NPDTGVLTVS
1310 1320 1330 1340 1350
WERSTTPDIT GYRITTTPTN GQQGYSLEEV VHADQSSCTF ENLSPGLEYN
1360 1370 1380 1390 1400
VSVYTVKNDK ESVPISDTII PAVPPPTDLR FTNVGPDTIR VTWAPPPSIE
1410 1420 1430 1440 1450
LTNFLVRYSP VKNEEDVAEL SISPSDNAVV LTNLLPGTEY LVSVSSVYEQ
1460 1470 1480 1490 1500
HESIPLRGRQ KTGLDSPTGI DFSDITANSF TVYWIAPRAT ITGYKIRHHP
1510 1520 1530 1540 1550
EHMGGRPRED RVPPSRNSIT LTNLIPGVEY VVSIVAVNGR EESPPLVGQQ
1560 1570 1580 1590 1600
STVSDVPRDL QVIATTPTSL LISWDAPAVT VRYYRITYGE TGGNSPVQEF
1610 1620 1630 1640 1650
TVPGSKSTAT ISGLKPGVDY TITVYAVTGR GDSPASSKPV SIDYRTEIDK
1660 1670 1680 1690 1700
PSQMQVTDVQ DNSISVRWLP SSSHVTGYRV TTTPKNGSGP SKTKTVGPDQ
1710 1720 1730 1740 1750
TEMTIEGLQP TVEYVVSVYA QNQNGESQPL VQTAVTNIDR PKGLAFTDVD
1760 1770 1780 1790 1800
VDSIKIAWES PQGQVSRYRV TYSSPEDGIH ELFPAPDGEE DTAELQGLRP
1810 1820 1830 1840 1850
GSEYTVSVVA LHDDMESQPL IGTQSTAIPA PTNLKFTQVT PTSLTAQWTA
1860 1870 1880 1890 1900
PNVQLTGYRV RVTPKEKTGP MKEINLAPDS SSVVVSGLMV ATKYEVSIYA
1910 1920 1930 1940 1950
LKDTLTSRPA QGVVTTLENV SPPRRARVTD ATETTITISW RTKTETITGF
1960 1970 1980 1990 2000
QVDAVPANGQ TPIQRTIKPD VRSYTITGLQ PGTDYKIYLY TLNDNARSSP
2010 2020 2030 2040 2050
VVIDASTAID APSNLRFLAT TPNSLLVSWQ PPRAKITGYI IKYEKPGSPP
2060 2070 2080 2090 2100
REVVPRPRPG VTEATITGLE PATEYTIQVI ALKNNQKSEP LIGRKRTDEL
2110 2120 2130 2140 2150
PQLVTLPHPN LHGPEILDVP STVQKTPFVT KPGYDTGNGI QLPGTSGQQP
2160 2170 2180 2190 2200
SLGQQMIFEE HGFRRTTPPT TATPVRHRPG PYTPNVNEEI QVGHVPRGDV
2210 2220 2230 2240 2250
DHHLYPHVLG LNPNASTGQE ALSQTTISWT PFQESSEYII SCHPVGIDEE
2260 2270 2280 2290 2300
PLQFRVPGTS ASATLTGLTR GATYNIIVEA LKDQKRHKIR EEVVTVGNSV
2310 2320 2330 2340 2350
DQGLSQPTDD SCFDPYTVSH YAIGEEWERL SESGFKLSCQ CLGFGSGHFR
2360 2370 2380 2390 2400
CDSSKWCHDN GVNYKIGEKW DRQGENGQMM SCTCLGNGKG EFKCDPHEAT
2410 2420 2430 2440 2450
CYDDGKTYHV GEQWQKEYLG AICSCTCFGG QRGWRCDNCR RPGAELGPEG
2460 2470 2480 2490
STGHSYNQYS QRYHQRTNTN VNCPIECFMP LDVQADIEDS RE
Length:2,492
Mass (Da):273,771
Last modified:June 5, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49CAA8F404D95A51
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQIR01032492 Transcribed RNA Translation: HCZ87967.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQIR01032492 Transcribed RNA Translation: HCZ87967.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00061 FN1, 12 hits
cd00062 FN2, 2 hits
cd00063 FN3, 15 hits
Gene3Di2.10.10.10, 2 hits
2.60.40.10, 16 hits
InterProiView protein in InterPro
IPR000083 Fibronectin_type1
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR000562 FN_type2_dom
IPR036943 FN_type2_sf
IPR013783 Ig-like_fold
IPR013806 Kringle-like
PfamiView protein in Pfam
PF00039 fn1, 12 hits
PF00040 fn2, 2 hits
PF00041 fn3, 15 hits
SMARTiView protein in SMART
SM00058 FN1, 12 hits
SM00059 FN2, 2 hits
SM00060 FN3, 16 hits
SUPFAMiSSF49265 SSF49265, 10 hits
SSF57440 SSF57440, 2 hits
PROSITEiView protein in PROSITE
PS01253 FN1_1, 6 hits
PS51091 FN1_2, 12 hits
PS00023 FN2_1, 1 hit
PS51092 FN2_2, 2 hits
PS50853 FN3, 16 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A480EIV0_PIG
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A480EIV0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 5, 2019
Last sequence update: June 5, 2019
Last modified: July 3, 2019
This is version 2 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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