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Entry version 2 (03 Jul 2019)
Sequence version 1 (05 Jun 2019)
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Protein
Submitted name:

Integral membrane protein GPR155 isoform X1

Gene
N/A
Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Integral membrane protein GPR155 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei44 – 61HelicalSequence analysisAdd BLAST18
    Transmembranei82 – 100HelicalSequence analysisAdd BLAST19
    Transmembranei120 – 142HelicalSequence analysisAdd BLAST23
    Transmembranei154 – 172HelicalSequence analysisAdd BLAST19
    Transmembranei184 – 206HelicalSequence analysisAdd BLAST23
    Transmembranei227 – 250HelicalSequence analysisAdd BLAST24
    Transmembranei262 – 280HelicalSequence analysisAdd BLAST19
    Transmembranei292 – 311HelicalSequence analysisAdd BLAST20
    Transmembranei331 – 352HelicalSequence analysisAdd BLAST22
    Transmembranei364 – 384HelicalSequence analysisAdd BLAST21
    Transmembranei404 – 422HelicalSequence analysisAdd BLAST19
    Transmembranei434 – 453HelicalSequence analysisAdd BLAST20
    Transmembranei459 – 489HelicalSequence analysisAdd BLAST31
    Transmembranei501 – 519HelicalSequence analysisAdd BLAST19
    Transmembranei539 – 560HelicalSequence analysisAdd BLAST22
    Transmembranei677 – 698HelicalSequence analysisAdd BLAST22
    Transmembranei710 – 731HelicalSequence analysisAdd BLAST22

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

    Membrane

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini798 – 853DEPInterPro annotationAdd BLAST56

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni571 – 592DisorderedSequence analysisAdd BLAST22
    Regioni857 – 885DisorderedSequence analysisAdd BLAST29

    Compositional bias

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi870 – 885PolyampholyteSequence analysisAdd BLAST16

    Keywords - Domaini

    Transmembrane, Transmembrane helixSequence analysis

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd04443 DEP_GPR155, 1 hit

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    1.10.10.10, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR000591 DEP_dom
    IPR037368 GPR155_DEP
    IPR004776 Mem_trans
    IPR036388 WH-like_DNA-bd_sf
    IPR036390 WH_DNA-bd_sf

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00610 DEP, 1 hit
    PF03547 Mem_trans, 2 hits

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM00049 DEP, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF46785 SSF46785, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS50186 DEP, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    A0A480DZN1-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MNSFSDLSAK NLTIAVNMTN TLPSTVAHGF NSTNDPPSMS ITRLFPALLE
    60 70 80 90 100
    CFGIVLCGYI AGRANVITST QAKGLGNFVS RFALPALLFK NMVVLNFSNV
    110 120 130 140 150
    DALLFKNMVV LNFSNVDWSF LYSILIAKAS VFFIVCVLTL LVASPDSRFS
    160 170 180 190 200
    KAGLFPIFAT QSNDFALGYP IVEALYQTTY PEYLQYIYLV APISLMMLNP
    210 220 230 240 250
    IGFIFCEIQK WRDTQNASQN KVKIVGLGLL RVLQNPIVFM VFIGIAFNFI
    260 270 280 290 300
    LDQKVPVYME NFLDGLANSF SGSALFYLGL TMVGKIKKLK KSAFVVLILL
    310 320 330 340 350
    ITAKLLVLPL LCREMVELLD KGDNVVNHTS LSNYAFLYGV FPVAPGVAIF
    360 370 380 390 400
    ATQFNMEVEI ITSGMVISTF VSAPIMYVSA WLLTFPTMDP KPLAYAIQNV
    410 420 430 440 450
    SFDISIISLV SLIWSLAILL LSKKYKQLPH MLTINLLIAQ SIVCAGMMIW
    460 470 480 490 500
    NFVKEKNFVG QILVFVLLYS SLYSTYLWTG LLAISLFLLK KREGVQIPVG
    510 520 530 540 550
    IIIISGWGIP ALLVGVLLIT GKHNGESIDS AFFYGKEQMI ITAVTLFCSI
    560 570 580 590 600
    VIAGISLMCM NRTSQAGRYE GFGQSQDHKA PEPGNTAFEE TPAPIDEPKP
    610 620 630 640 650
    FTSSIPETSC CSCSMGNGEL CCPSTEPVAN ISTSGPVTPS FEKNEHCVSR
    660 670 680 690 700
    CNSQSCILAQ EEELYLQTGD QQLTRHVLLC LLLIIGLFAN LSSCLWWLFN
    710 720 730 740 750
    QEPGRLYVEL QFFCAVFNFG QGFISFGIFG LDKHLIILPF KRRLEFLWNN
    760 770 780 790 800
    KETAENRGSP VPEEIKMTCQ QFIHYHRDLC IQNIVRERRC GPKTSAGTFC
    810 820 830 840 850
    GCDLVNWLIE VGLASDRGEA VIYGDRLVQG GVIQHITNEY EFRDEYLFYR
    860 870 880
    FLQKSPEHSP PATNTHTPQQ ERYKEIEHSS PPTKT
    Length:885
    Mass (Da):98,570
    Last modified:June 5, 2019 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB60C1F69CB39A269
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    DQIR01025518 Transcribed RNA Translation: HCZ80993.1

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    DQIR01025518 Transcribed RNA Translation: HCZ80993.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protocols and materials databases

    Structural Biology KnowledgebaseSearch...

    Family and domain databases

    CDDicd04443 DEP_GPR155, 1 hit
    Gene3Di1.10.10.10, 1 hit
    InterProiView protein in InterPro
    IPR000591 DEP_dom
    IPR037368 GPR155_DEP
    IPR004776 Mem_trans
    IPR036388 WH-like_DNA-bd_sf
    IPR036390 WH_DNA-bd_sf
    PfamiView protein in Pfam
    PF00610 DEP, 1 hit
    PF03547 Mem_trans, 2 hits
    SMARTiView protein in SMART
    SM00049 DEP, 1 hit
    SUPFAMiSSF46785 SSF46785, 1 hit
    PROSITEiView protein in PROSITE
    PS50186 DEP, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A480DZN1_PIG
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A480DZN1
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 5, 2019
    Last sequence update: June 5, 2019
    Last modified: July 3, 2019
    This is version 2 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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