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Entry version 4 (16 Oct 2019)
Sequence version 1 (05 Jun 2019)
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Protein
Submitted name:

CAP-Gly domain-containing linker protein 1 isoform X1

Gene

CLIP1

Organism
Physeter macrocephalus (Sperm whale) (Physeter catodon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
CAP-Gly domain-containing linker protein 1 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhyseter macrocephalus (Sperm whale) (Physeter catodon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9755 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaCetaceaOdontocetiPhyseteridaePhyseter
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000248484 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini78 – 120CAP-GlyInterPro annotationAdd BLAST43
Domaini232 – 274CAP-GlyInterPro annotationAdd BLAST43

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 21DisorderedSequence analysisAdd BLAST21
Regioni128 – 205DisorderedSequence analysisAdd BLAST78
Regioni1298 – 1321DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili350 – 377Sequence analysisAdd BLAST28
Coiled coili403 – 451Sequence analysisAdd BLAST49
Coiled coili477 – 497Sequence analysisAdd BLAST21
Coiled coili512 – 532Sequence analysisAdd BLAST21
Coiled coili556 – 576Sequence analysisAdd BLAST21
Coiled coili581 – 615Sequence analysisAdd BLAST35
Coiled coili624 – 644Sequence analysisAdd BLAST21
Coiled coili660 – 680Sequence analysisAdd BLAST21
Coiled coili685 – 817Sequence analysisAdd BLAST133
Coiled coili832 – 866Sequence analysisAdd BLAST35
Coiled coili874 – 925Sequence analysisAdd BLAST52
Coiled coili944 – 978Sequence analysisAdd BLAST35
Coiled coili987 – 1035Sequence analysisAdd BLAST49
Coiled coili1058 – 1192Sequence analysisAdd BLAST135
Coiled coili1196 – 1234Sequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi139 – 202PolarSequence analysisAdd BLAST64

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K10421

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.190, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR032108 CLIP1_ZNF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01302 CAP_GLY, 2 hits
PF16641 CLIP1_ZNF, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01052 CAP_GLY, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF74924 SSF74924, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00845 CAP_GLY_1, 2 hits
PS50245 CAP_GLY_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A455AL69-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSMLKPSGLK APTKILKPGS TALKTPASVA APIEKTISSE KASSTPSAET
60 70 80 90 100
QEEFVDDFRV GERVWVNGNK PGFIQFLGET QFAPGQWAGI VLDEPIGKND
110 120 130 140 150
GSVAGIRYFQ CEPLKGIFTR PSKLTRKVQA EDEADGLQTT HASRATSPLS
160 170 180 190 200
TSTASMVSSS PATPSSIPHK SPQPTAKEPS ATSQISNLTK TTSESISNLS
210 220 230 240 250
EAGSIKKGER ELKIGDRVLV GGTKAGVVRF LGETDFAKGE WCGVELDEPL
260 270 280 290 300
GKNDGAVAGT RYFQCQPKYG LFAPVHKVTK IGFPSTTPAK AKAAAVRRVM
310 320 330 340 350
ATTPANLTRS PSASSLSSMS SVASSVSSKP SRTGLLTETS SRYARKISGT
360 370 380 390 400
TALQEALKEK QQHIEQLLAE RDLERAEVAK ATSHVGEIEQ ELALARDGHD
410 420 430 440 450
QHVLELEAKM DQLRAMVEAA DREKVELLNQ LEEERRKVED LQFRVEEESI
460 470 480 490 500
TKGDLEQKSQ ISEDPENTQT KLEHARIKEL EQSLLFEKTK ADKLQRELED
510 520 530 540 550
TRVATVSEKS RIMELEKDLA FRMQEVAELR RRLESSKPAG DVDMSLSLLQ
560 570 580 590 600
EISALQEKLE ATHTDHQKEI TSLKEHFGAR EETHQKEIKA LQATTEKLSK
610 620 630 640 650
ENESLKSKLD HANKENSDVI ALWKSKLETA IASHQQAMEE LKVSFSKGVG
660 670 680 690 700
TEMAEFAELK TQIEKMRLDY QHEIENLQNK QDLERSAHTK ELEALRAKLM
710 720 730 740 750
KVIKEKENSL EAIKSKLDKA EDQHLVEMED TLNKLQEAEL KVKELEVLQA
760 770 780 790 800
KCNEQTKVID NFTSQLKAAE EKLLDLDALR KASSEGKSEI ETLRQQLEAA
810 820 830 840 850
EKQIKNLEIE KNAESGKASS ITKELQGKEL MLNKLQEHLS EVSQVKEALE
860 870 880 890 900
KELQILKENF ADASEQAVSV QRSMQETVNK LHQKEEQFNV LSSELEKLRE
910 920 930 940 950
NLTDMEAKFR ERDEREEQLI KAKEKLENDI AVIMKMSGDS SSQLTKMNDE
960 970 980 990 1000
LRLKERNVEE LQLRLSKANE NASLLQESIG DVTLKAAQSQ QEAARKHEEE
1010 1020 1030 1040 1050
KKELLKKLSD LERKMQMSHN ECQELKGRYE EASSETQAKH EEVLQNLQKM
1060 1070 1080 1090 1100
LLDTGELLKA SQKENSDLLQ EMEELRRQAD KARAAQTAED AMQIMEQMTK
1110 1120 1130 1140 1150
EKTETLASLE DSKQTNEKLQ NELDTLKENN LKNMEELNKS KELLTVENQK
1160 1170 1180 1190 1200
MEEFKKEIET LKQAAAQKSQ QLSALQEENV KLAEELGRSR DEVTGHQKLE
1210 1220 1230 1240 1250
EERSVLNNQL LEMKKRESKL IKDADEEKAS LQKSISITSA LLTEKDAELE
1260 1270 1280 1290 1300
KLRNEVTALR GENASAKSLR AVVQSLESDK AKLELKVKNL ELQLKENKRQ
1310 1320 1330 1340 1350
LSSSSGNTDT QAEEDERAQE SQQMIDFLNS VIVDLQRKNQ DLKMKVEMMS
1360 1370 1380 1390 1400
EAALNGNGDD MNNYDSDDQE KQSKKKPRLF CDICDCFDLH DTEDCPTQAQ
1410 1420 1430 1440
MSEDPPHSTH HGSRSEERPY CEICEMFGHW ATNCNDDETF
Length:1,440
Mass (Da):162,063
Last modified:June 5, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF5BF072B06C90149
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2Y9FTK8A0A2Y9FTK8_PHYMC
CAP-Gly domain-containing linker pr...
CLIP1
1,438Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A455AJA7A0A455AJA7_PHYMC
CAP-Gly domain-containing linker pr...
CLIP1
1,216Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A455AJN1A0A455AJN1_PHYMC
CAP-Gly domain-containing linker pr...
CLIP1
1,392Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A455AL55A0A455AL55_PHYMC
CAP-Gly domain-containing linker pr...
CLIP1
1,221Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A455AL77A0A455AL77_PHYMC
CAP-Gly domain-containing linker pr...
CLIP1
1,254Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A455AXS0A0A455AXS0_PHYMC
CAP-Gly domain-containing linker pr...
CLIP1
1,394Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_028336628.1, XM_028480827.1
XP_028336629.1, XM_028480828.1
XP_028336630.1, XM_028480829.1
XP_028336631.1, XM_028480830.1
XP_028336632.1, XM_028480831.1
XP_028336633.1, XM_028480832.1
XP_028336634.1, XM_028480833.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pcad:102994904

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_028336628.1, XM_028480827.1
XP_028336629.1, XM_028480828.1
XP_028336630.1, XM_028480829.1
XP_028336631.1, XM_028480830.1
XP_028336632.1, XM_028480831.1
XP_028336633.1, XM_028480832.1
XP_028336634.1, XM_028480833.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

KEGGipcad:102994904

Phylogenomic databases

KOiK10421

Family and domain databases

Gene3Di2.30.30.190, 2 hits
InterProiView protein in InterPro
IPR036859 CAP-Gly_dom_sf
IPR000938 CAP-Gly_domain
IPR032108 CLIP1_ZNF
PfamiView protein in Pfam
PF01302 CAP_GLY, 2 hits
PF16641 CLIP1_ZNF, 2 hits
SMARTiView protein in SMART
SM01052 CAP_GLY, 2 hits
SUPFAMiSSF74924 SSF74924, 2 hits
PROSITEiView protein in PROSITE
PS00845 CAP_GLY_1, 2 hits
PS50245 CAP_GLY_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A455AL69_PHYMC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A455AL69
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 5, 2019
Last sequence update: June 5, 2019
Last modified: October 16, 2019
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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