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Entry version 6 (16 Oct 2019)
Sequence version 1 (08 May 2019)
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Protein

Bms1-type G domain-containing protein

Gene

BMS1

Organism
Capra hircus (Goat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bms1-type G domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BMS1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCapra hircus (Goat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9925 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeCapra
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000291000 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 28

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini80 – 246Bms1-type GInterPro annotationAdd BLAST167

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 42DisorderedSequence analysisAdd BLAST42
Regioni399 – 638DisorderedSequence analysisAdd BLAST240
Regioni1225 – 1285DisorderedSequence analysisAdd BLAST61

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi21 – 42PolyampholyteSequence analysisAdd BLAST22
Compositional biasi412 – 438PolyampholyteSequence analysisAdd BLAST27
Compositional biasi439 – 473AcidicSequence analysisAdd BLAST35
Compositional biasi474 – 498PolyampholyteSequence analysisAdd BLAST25
Compositional biasi499 – 537AcidicSequence analysisAdd BLAST39
Compositional biasi538 – 556PolyampholyteSequence analysisAdd BLAST19
Compositional biasi557 – 587PolarSequence analysisAdd BLAST31
Compositional biasi593 – 611AcidicSequence analysisAdd BLAST19

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153195

KEGG Orthology (KO)

More...
KOi
K14569

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01882 BMS1, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012948 AARP2CN
IPR039761 Bms1/Tsr1
IPR037875 Bms1_N
IPR007034 BMS1_TSR1_C
IPR030387 G_Bms1/Tsr1_dom
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR12858 PTHR12858, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08142 AARP2CN, 1 hit
PF04950 RIBIOP_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00785 AARP2CN, 1 hit
SM01362 DUF663, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51714 G_BMS1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A452FSI8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METKDQKKHR KKNSGPKAEK KKKRHLQDLQ LGDEEDARKR NPKAFAVQSA
60 70 80 90 100
VRMARSFHRT QDLKTKKHHI PVVDRTPLEP PPIVVVVMGP PKVGKSTLIQ
110 120 130 140 150
CLIRNFTRQK LTEIRGPVTI VSGKKRRLTI IECGCDINMM IDLAKVADLV
160 170 180 190 200
LMLIDASFGF EMETFEFLNI CQVHGFPKIM GVLTHLDSFK HNKQLKKTKK
210 220 230 240 250
RLKHRFWTEV YPGAKLFYLS GMVHGEYQNQ EIHNLGRFIT VMKFRPLTWQ
260 270 280 290 300
TSHPYILADR MEDLTNPEDI RTNTKCDRKV SLYGYLRGAH LKNKSQVHIP
310 320 330 340 350
GVGDFAVSDV SFLPDPCALP EQQKKRCLNE KEKLVYAPLS GVGGVLYDKD
360 370 380 390 400
AVYVDLGGSH GFQESEEVRP THELVQSLIS THSTIDAKMA SSRVTLFTDS
410 420 430 440 450
KPLGSEDIDN QGQWMPKEEK QVDLKTGRVR RKAIFGDEEE DESGDSDDED
460 470 480 490 500
DEMSEGDRLE NSCSDDETEE GPDAEVPDKQ YMSRKGIKRQ KLEMEEDFEV
510 520 530 540 550
DLPAFADSDD DLERSSVEEE AEEADESSEE EDSTAEEERD IFESKAVREG
560 570 580 590 600
GKPELLQTDD SSDSLNMEKS LTRKKATFTT SDSGHCTAEE AFASEDEPEG
610 620 630 640 650
NSSLSTEEED SENEEAIRKK FPKPQVVSSQ KLGSGNLIDE TSDIEDLLKE
660 670 680 690 700
EEDYKEENNY STETSGALKW KEDLSRKAAE AFLRQQQTTP NLRKLIYGTV
710 720 730 740 750
TEDNEEEDGD NGEELGGLFR VSQPASECKH KADSLDCSRF HVEAPHDWDL
760 770 780 790 800
EEVMNSIRDC FVTGKWEEDK DAAKILAEDE ELYGDFEDLE TGDVHRGKPG
810 820 830 840 850
PDTQVEDVEE EIKEEIDPSA EESAKKKHLE KKRKLKEMFD AEYDEGESTY
860 870 880 890 900
FDDLKGEMQK QAQLNRAEFE DQDDEARVQY EGFRPGMYVR IEIENVPCEF
910 920 930 940 950
VLNFDPHYPI ILGGLGNSEG NVGYVQMRLK KHRWYKKILK SRDPIIFSVG
960 970 980 990 1000
WRRFQTIPLY YIEDHNGRQR LLKYTPQHMH CGATFWGPIT PQGTGFLAVQ
1010 1020 1030 1040 1050
SVSGNMPDFR IAATGVVLDL DKSIKIVKKL KLTGFPYKIF KNTSFIKGMF
1060 1070 1080 1090 1100
NSALEVAKFE GAVIRTVSGI RGQIKKALRA PEGAFRATFE DKLLMSDIVF
1110 1120 1130 1140 1150
MRTWYPVSVP AFYNPVTSLL KPIGEKDTWS GMRTTGQLRL AHGIKLKANK
1160 1170 1180 1190 1200
DSLYKPIVRQ KKHFNSLHIP KALQKALPFK SKPKTQAKAG KTPKDRVRPA
1210 1220 1230 1240 1250
VIREPHERKI LALLDALSTV HSEKMKKAKE QRHLHNKEHF KMKQKEEEEK
1260 1270 1280
LKRQKDLRKK LYRIQGQKER RNQKSSLKGP EEQLK
Length:1,285
Mass (Da):146,857
Last modified:May 8, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7BD4D850DBED9400
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
LWLT01000030 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_005699082.2, XM_005699025.2
XP_005699085.2, XM_005699028.3
XP_005699086.2, XM_005699029.2
XP_005699087.2, XM_005699030.3
XP_017897760.1, XM_018042271.1
XP_017897761.1, XM_018042272.1
XP_017897762.1, XM_018042273.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSCHIT00000035113; ENSCHIP00000027245; ENSCHIG00000023251
ENSCHIT00000035124; ENSCHIP00000027256; ENSCHIG00000023251

Database of genes from NCBI RefSeq genomes

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GeneIDi
102182945

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
chx:102182945

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LWLT01000030 Genomic DNA No translation available.
RefSeqiXP_005699082.2, XM_005699025.2
XP_005699085.2, XM_005699028.3
XP_005699086.2, XM_005699029.2
XP_005699087.2, XM_005699030.3
XP_017897760.1, XM_018042271.1
XP_017897761.1, XM_018042272.1
XP_017897762.1, XM_018042273.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSCHIT00000035113; ENSCHIP00000027245; ENSCHIG00000023251
ENSCHIT00000035124; ENSCHIP00000027256; ENSCHIG00000023251
GeneIDi102182945
KEGGichx:102182945

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9790

Phylogenomic databases

GeneTreeiENSGT00940000153195
KOiK14569

Family and domain databases

CDDicd01882 BMS1, 1 hit
InterProiView protein in InterPro
IPR012948 AARP2CN
IPR039761 Bms1/Tsr1
IPR037875 Bms1_N
IPR007034 BMS1_TSR1_C
IPR030387 G_Bms1/Tsr1_dom
IPR027417 P-loop_NTPase
PANTHERiPTHR12858 PTHR12858, 2 hits
PfamiView protein in Pfam
PF08142 AARP2CN, 1 hit
PF04950 RIBIOP_C, 1 hit
SMARTiView protein in SMART
SM00785 AARP2CN, 1 hit
SM01362 DUF663, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51714 G_BMS1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A452FSI8_CAPHI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A452FSI8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 8, 2019
Last sequence update: May 8, 2019
Last modified: October 16, 2019
This is version 6 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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