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UniProtKB - A0A452F4Q6 (A0A452F4Q6_CAPHI)

Entry version 9 (10 Feb 2021)
Sequence version 1 (08 May 2019)
Previous versions | rss
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Protein
Submitted name:

Uncharacterized protein

Gene

ANK2

Organism
Capra hircus (Goat)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANK2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCapra hircus (Goat)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9925 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Ruminantia › Pecora › Bovidae › Caprinae › Capra
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000291000 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini11 – 794ANK_REP_REGIONInterPro annotationAdd BLAST784
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati44 – 76ANKPROSITE-ProRule annotationAdd BLAST33
Repeati77 – 109ANKPROSITE-ProRule annotationAdd BLAST33
Repeati110 – 142ANKPROSITE-ProRule annotationAdd BLAST33
Repeati213 – 245ANKPROSITE-ProRule annotationAdd BLAST33
Repeati246 – 278ANKPROSITE-ProRule annotationAdd BLAST33
Repeati279 – 311ANKPROSITE-ProRule annotationAdd BLAST33
Repeati312 – 344ANKPROSITE-ProRule annotationAdd BLAST33
Repeati345 – 377ANKPROSITE-ProRule annotationAdd BLAST33
Repeati378 – 410ANKPROSITE-ProRule annotationAdd BLAST33
Repeati411 – 443ANKPROSITE-ProRule annotationAdd BLAST33
Repeati444 – 476ANKPROSITE-ProRule annotationAdd BLAST33
Repeati477 – 509ANKPROSITE-ProRule annotationAdd BLAST33
Repeati510 – 542ANKPROSITE-ProRule annotationAdd BLAST33
Repeati543 – 575ANKPROSITE-ProRule annotationAdd BLAST33
Repeati576 – 608ANKPROSITE-ProRule annotationAdd BLAST33
Repeati609 – 641ANKPROSITE-ProRule annotationAdd BLAST33
Repeati642 – 674ANKPROSITE-ProRule annotationAdd BLAST33
Repeati675 – 707ANKPROSITE-ProRule annotationAdd BLAST33
Repeati708 – 740ANKPROSITE-ProRule annotationAdd BLAST33
Repeati741 – 773ANKPROSITE-ProRule annotationAdd BLAST33
Domaini949 – 1104ZU5InterPro annotationAdd BLAST156
Domaini1106 – 1252ZU5InterPro annotationAdd BLAST147
Domaini3500 – 3584DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1516 – 1537DisorderedSequence analysisAdd BLAST22
Regioni1589 – 2070DisorderedSequence analysisAdd BLAST482
Regioni2128 – 2420DisorderedSequence analysisAdd BLAST293
Regioni2443 – 2699DisorderedSequence analysisAdd BLAST257
Regioni2712 – 2806DisorderedSequence analysisAdd BLAST95
Regioni2829 – 2892DisorderedSequence analysisAdd BLAST64
Regioni2928 – 2954DisorderedSequence analysisAdd BLAST27
Regioni3000 – 3038DisorderedSequence analysisAdd BLAST39
Regioni3067 – 3174DisorderedSequence analysisAdd BLAST108
Regioni3195 – 3393DisorderedSequence analysisAdd BLAST199
Regioni3619 – 3642DisorderedSequence analysisAdd BLAST24
Regioni3654 – 3767DisorderedSequence analysisAdd BLAST114
Regioni3832 – 3854DisorderedSequence analysisAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3409 – 3429Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1599 – 1632PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1657 – 1684PolyampholyteSequence analysisAdd BLAST28
Compositional biasi1711 – 1749PolyampholyteSequence analysisAdd BLAST39
Compositional biasi1760 – 1774PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1775 – 1840PolarSequence analysisAdd BLAST66
Compositional biasi1908 – 1922PolarSequence analysisAdd BLAST15
Compositional biasi1945 – 1978PolyampholyteSequence analysisAdd BLAST34
Compositional biasi2009 – 2052PolyampholyteSequence analysisAdd BLAST44
Compositional biasi2189 – 2218PolyampholyteSequence analysisAdd BLAST30
Compositional biasi2294 – 2308PolarSequence analysisAdd BLAST15
Compositional biasi2456 – 2490PolarSequence analysisAdd BLAST35
Compositional biasi2499 – 2557PolyampholyteSequence analysisAdd BLAST59
Compositional biasi2565 – 2580PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2628 – 2655PolarSequence analysisAdd BLAST28
Compositional biasi2656 – 2683PolyampholyteSequence analysisAdd BLAST28
Compositional biasi2712 – 2732PolarSequence analysisAdd BLAST21
Compositional biasi2747 – 2764PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2770 – 2784PolarSequence analysisAdd BLAST15
Compositional biasi2829 – 2844PolarSequence analysisAdd BLAST16
Compositional biasi2860 – 2875PolarSequence analysisAdd BLAST16
Compositional biasi2929 – 2954PolarSequence analysisAdd BLAST26
Compositional biasi3003 – 3034PolarSequence analysisAdd BLAST32
Compositional biasi3128 – 3174PolarSequence analysisAdd BLAST47
Compositional biasi3225 – 3253PolarSequence analysisAdd BLAST29
Compositional biasi3316 – 3346PolyampholyteSequence analysisAdd BLAST31
Compositional biasi3373 – 3389PolarSequence analysisAdd BLAST17
Compositional biasi3668 – 3682PolarSequence analysisAdd BLAST15
Compositional biasi3696 – 3718PolarSequence analysisAdd BLAST23
Compositional biasi3835 – 3851PolarSequence analysisAdd BLAST17

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155279

Identification of Orthologs from Complete Genome Data

More...OMAi		LLCSITX

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
IPR000906, ZU5_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00023, Ank, 2 hits
PF12796, Ank_2, 6 hits
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
PF00791, ZU5, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01415, ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00248, ANK, 23 hits
SM00005, DEATH, 1 hit
SM00218, ZU5, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47986, SSF47986, 1 hit
SSF48403, SSF48403, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 20 hits
PS50017, DEATH_DOMAIN, 1 hit
PS51145, ZU5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A452F4Q6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VVALFCFSQS DSNASFLRAA RAGNLDKVVE YLKGGIDINT CNQNGLNALH 
        60         70         80         90        100
LAAKEGHVGL VQELLGRGSA VDSATKKGNT ALHIASLAGQ AEVVKVLVKE 
       110        120        130        140        150
GANINAQSQN GFTPLYMAAQ ENHIDVVKYL LENGANQSTA TEDGFTPLAV 
       160        170        180        190        200
ALQQGHNQAV AILLENDTKG KVRLPALHIA ARKDDTKSAA LLLQNDHNAD 
       210        220        230        240        250
VQSKMMVNRT TESGFTPLHI AAHYGNVNVA TLLLNRGAAV DFTARNGITP 
       260        270        280        290        300
LHVASKRGNT NMVKLLLDRG GQIDAKTRDG LTPLHCAARS GHDQVVELLL 
       310        320        330        340        350
ERGAPLLART KNGLSPLHMA AQGDHVECVK HLLQHKAPVD DVTLDYLTAL 
       360        370        380        390        400
HVAAHCGHYR VTKLLLDKRA NPNARALNGF TPLHIACKKN RIKVMELLVK 
       410        420        430        440        450
YGASIQAITE SGLTPIHVAA FMGHLNIVLL LLQNGASPDV TNIRGETALH 
       460        470        480        490        500
MAARAGQVEV VRCLLRNGAL VDARAREEQT PLHIASRLGK TEIVQLLLQH 
       510        520        530        540        550
MAHPDAATTN GYTPLHISAR EGQVDVASVL LEAGAAHSLA TKKGFTPLHV 
       560        570        580        590        600
AAKYGSLDVA KLLLQRRAAA DSAGKNGLTP LHVAAHYDNQ KVALLLLEKG 
       610        620        630        640        650
ASPHATAKNG YTPLHIAAKK NQMQIASTLL SYGAETNIVT KQGVTPLHLA 
       660        670        680        690        700
SQEGHTDMVT LLLDKGANIH MSTKSGLTSL HLAAQEDKVN VADILTKHGA 
       710        720        730        740        750
DQDAHTKLGY TPLIVACHYG NVKMVNFLLK QGANVNAKTK NGYTPLHQAA 
       760        770        780        790        800
QQGHTHIINV LLQHGAKPNA TTANGNTALA IAKRLGYISV VDTLKVVTEE 
       810        820        830        840        850
VTTTTTTITE KHKLNVPETM TEVLDVSDEE GDDTMTGDGG EYLRPEDLKE 
       860        870        880        890        900
LGDDSLPSSQ FLDGMNYLRY SLEGGRSDSL RSFSSDRSHT LSHASYLRDS 
       910        920        930        940        950
AMIDDTVVIP SHQVTTLAKE AERNSYRLSW GTENLDNVAL SSSPIHSGFL 
       960        970        980        990       1000
VSFMVDARGG AMRGCRHNGL RIIIPPRKCT APTRVTCRLV KRHRLATMPP 
      1010       1020       1030       1040       1050
MVEGEGLASR LIEVGPSGAQ FLGPVIVEIP HFAALRGKER ELVVLRSENG 
      1060       1070       1080       1090       1100
DSWKEHYCEY TEEELNEILN GMDEVLDTPE DLEKKRVCRI ITRDFPQYFA 
      1110       1120       1130       1140       1150
VVSRIKQDSN LIGPEGGVLS STVVPQVQAV FPEGALTKRI RVGLQAQPMH 
      1160       1170       1180       1190       1200
SELVKKILGN KATFSPIVTL EPRRRKFHKP ITMTIPVPKA SSDVMLNGFG 
      1210       1220       1230       1240       1250
GDAPTLRLLC SITGGTTPAQ WEDITGTTPL TFVNECVSFT TNVSARFWLI 
      1260       1270       1280       1290       1300
DCRQIQESVT FASQVYREII CVPYMAKFVV FAKSHDPIEA RLRCFCMTDD 
      1310       1320       1330       1340       1350
KVDKTLEQQE NFAEVARSRD VEVLEGKPIY VDCFGNLVPL TKSGQHHIFS 
      1360       1370       1380       1390       1400
FFAFKENRLP LFVKVRDTTQ EPCGRLSFMK EPKSTRGLVH QAICNLNITL 
      1410       1420       1430       1440       1450
PIYTKESESD QEQEEEVIIW PCHDETESTE TSVLKSHLVN EVPVLASPDL 
      1460       1470       1480       1490       1500
LSEVSEMKQD LIKMTAILTT DGSDRAGSIK VKELVKAAEE EPGEPFEIVE 
      1510       1520       1530       1540       1550
RVKEDLEKVN EILRSGTCTG DEGSVPRSQP EKELEEEEWV IVSEEEIEEA 
      1560       1570       1580       1590       1600
KQKASSEITE YPCIEIRLDK ETKAEVEKDS TGLVNYLTED LNSYVPPHEE 
      1610       1620       1630       1640       1650
QPQKERGMVG EKREAQGPSR RSESEGKDAP SEETQSTQKQ PKPSLGIKKP 
      1660       1670       1680       1690       1700
VRRKLKEKQK QKEDSSQASA EKTELKKGSS EESLDEDTGS APEPLPAVKA 
      1710       1720       1730       1740       1750
TSPLIEETPI GSIKDKVKAL QKRVEDEQKG RSKLPVRVKG KEDVPKKITQ 
      1760       1770       1780       1790       1800
RTHLAASPSL KSERTERHTS LSSSAKTERH PPVSPSSKNE KHSPVSPSAK 
      1810       1820       1830       1840       1850
TERHSPVSSS SKTEKHSPVS PSTKTERHSP VSSSAKTERH PPVSPSGKTD 
      1860       1870       1880       1890       1900
KRPPGSPSGR TEKHPPVSPG RTEKRLLVSP AGRMEKHSPA SSSGKTEKHL 
      1910       1920       1930       1940       1950
PVSPSGKTDK QPPVSPTSKT ERIEETMSVR ELMKAFQSGQ DPSKHKTGLF 
      1960       1970       1980       1990       2000
EHKSAKQKQP QEKGRGRLEK ERGPIVTPRE VQKMESQTIK RGQRFLVTGL 
      2010       2020       2030       2040       2050
SEPRRAVRAS STGLKREDGA GEKEKSLNHK TPEPVQPVPE EESHKDSELA 
      2060       2070       2080       2090       2100
DDQGDMDLQI SPDRKTSTDF SDVIKQELED NDKYQQFRMT EEPEKAQLHL 
      2110       2120       2130       2140       2150
DQVLTSPFNT TFPLDYMKDE FLPALSLQSG TLPGSSESLK PEGVADSPCG 
      2160       2170       2180       2190       2200
SLMEGTPQIS SEESYKHEGL AETPETSPES LSFSPKKSEE QIGETHETTK 
      2210       2220       2230       2240       2250
LETAPESHSE KGHPSTKDVA DGSEGQGAAV TEAAESSAEC QLTEATPDPS 
      2260       2270       2280       2290       2300
KDMCPPQEGD SLGGQSVSLA KETPEGPTEE ATCDEGPVAH ISPSHEPQTD 
      2310       2320       2330       2340       2350
TEAQESIATK PSEEAEASPL SEAAVKAGSG TEPKPQAAIR SPQGLELALP 
      2360       2370       2380       2390       2400
SRESEVFSPG ADESFAVSHK DSLEASPVLE DNSSHKTPDS LEPSPLKESP 
      2410       2420       2430       2440       2450
CRDSLESSPV EPKMKAGILP SHFPLPSAVA KTELFTEVAS VRSRLLRDPD 
      2460       2470       2480       2490       2500
GSAEDDSLEQ TSLMESSGKS PLSPDTPSSE EVSYEVTPKT TDTPKPAVIP 
      2510       2520       2530       2540       2550
ECAEEDDSEN GEKKRFTPEE EMFKMVTKVK TFDELEQEAK QKRDYKREPK 
      2560       2570       2580       2590       2600
QEESSSSSDA DVDCSADTDE PKHTESVEDE SDAPVVVTAE GRKASSSSES 
      2610       2620       2630       2640       2650
EPELTQLKKG ADSGLLAEPV IRVQPPSPLP SSIDSNSSPE EIQFQPIVSK 
      2660       2670       2680       2690       2700
QYTFKMNEDA QEDSDKSEEE KDYKSRLPED SHALPIDGPE ISYDDLNGDT 
      2710       2720       2730       2740       2750
YQPKLCDSLG CEIGSPTNSA APVSSGLRSS PGDDVSEQLV IHKESLALQD 
      2760       2770       2780       2790       2800
TSEKDLEEEL DVPGVKSPQA DPPSESSPSF SSLPLCPASE AKELDEDVVS 
      2810       2820       2830       2840       2850
TASATEMEVA KTDQAFESLP EDCSIQDSLI TTQTDRSSLD VPVSDPTETD 
      2860       2870       2880       2890       2900
EIYEPQVISP YENVPSQSFF SGEESKTQTD TRHTSFHSSE EYSVTITSSV 
      2910       2920       2930       2940       2950
EDVVETSSSD KTVSSKEANF EDQVLEVESK QESTLQEVQS DGASSSLETT 
      2960       2970       2980       2990       3000
VQKTSTVVSE QISKVIITKT DVDSDSWSEI REDDEAFEAR VKEEEQKIFG 
      3010       3020       3030       3040       3050
LMVDRQSQGT TPDTTPARTP TEEGTPTSEQ NPFLFQEGKL FEMTRSGAID 
      3060       3070       3080       3090       3100
MTKRSYADES FHFFQIGQES REETLSQDMK EGGTGAEAPQ VETSAESLTL 
      3110       3120       3130       3140       3150
SESKETVDDE AELLPDDLSE EVEEIHTSDT PLSSQIDISA SIETSMKEAT 
      3160       3170       3180       3190       3200
STGLEDLPTR QMGDSLPLSS VKQTTCPDFP EQVVQVQLDF STVTRSIYSD 
      3210       3220       3230       3240       3250
RGDDSPDSSP EEQKSVIEIP TAPMENVPST ESKSKIPVRT IPTSTSIPPS 
      3260       3270       3280       3290       3300
VEYESSLSED FLPGLDEESK EDEAKPKSKI PVKAPAQRVE QQPSHLDSPL 
      3310       3320       3330       3340       3350
KKTDGPQGQD LTSSAPDDRS KSESDASLGM KTKCRVETRS YIETETESMG 
      3360       3370       3380       3390       3400
EEEELELESE EGATRPKIFT SRLPVKSKST TSSCRGPTSP TKDNKEHFFD 
      3410       3420       3430       3440       3450
LYRNSIEFFE EISDEASKLV DRLTQSEREQ DLVSDDESSS ALEVSVIENL 
      3460       3470       3480       3490       3500
PPVETENSIP EDIFDTRPIW DESIETLIER IPDENGHDRA EDQQDEQERI 
      3510       3520       3530       3540       3550
EERLAYIADH LGFSWTELAR ELDFTEEQIH QIRIENPNSL QDQSHALLKY 
      3560       3570       3580       3590       3600
WLERDGKHAT DTSLIECLTK INRMDIVHLM ETSTESLQER IGHSYAEIEQ 
      3610       3620       3630       3640       3650
TITLDHSEGF SVLQEELCTA QHKQKEEHAA SKEDEASDHP PIVSEEDISV 
      3660       3670       3680       3690       3700
GYSTFQDGIP KSEGDGSATE LLPQTQKEQV QRDFSGKMQD LPEDVTTPGT 
      3710       3720       3730       3740       3750
EMSETQKATG TSGSPAKTPE EIVTPPEEER LYLQTPTSSE RGGSPVVQEP 
      3760       3770       3780       3790       3800
EEPPESREES SPRKTSLVIV ESAEDQPQAF EKLDEDAAFQ KGDDMPDIPP 
      3810       3820       3830       3840       3850
ETVTEEEYID EHGHTVVKKV TRKIIRRFIS SDGTEKEEIT MQGTPQDSVS 
      3860       3870 
VEEGDGYSKV IKRIVLKSDT EQSEVSP
Length:3,877
Mass (Da):424,695
Last modified:May 8, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9DB7A75F973E69DB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A452F4F3A0A452F4F3_CAPHI
Uncharacterized protein
ANK2
3,933Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
LWLT01000006 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSCHIT00000026957; ENSCHIP00000019141; ENSCHIG00000018205

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LWLT01000006 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSCHIT00000026957; ENSCHIP00000019141; ENSCHIG00000018205

Phylogenomic databases

GeneTreeiENSGT00940000155279
OMAiLLCSITX

Family and domain databases

Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
IPR000906, ZU5_dom
PfamiView protein in Pfam
PF00023, Ank, 2 hits
PF12796, Ank_2, 6 hits
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
PF00791, ZU5, 1 hit
PRINTSiPR01415, ANKYRIN
SMARTiView protein in SMART
SM00248, ANK, 23 hits
SM00005, DEATH, 1 hit
SM00218, ZU5, 1 hit
SUPFAMiSSF47986, SSF47986, 1 hit
SSF48403, SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 20 hits
PS50017, DEATH_DOMAIN, 1 hit
PS51145, ZU5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A452F4Q6_CAPHI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A452F4Q6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 8, 2019
Last sequence update: May 8, 2019
Last modified: February 10, 2021
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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