UniProtKB - A0A410TLU6 (A0A410TLU6_9EURY)
Protein
Archaeal Rqc2 homolog aRqcH
Gene
rqcH
Organism
Halorubrum sp. BOL3-1
Status
Functioni
Probably part of the ribosome quality control system (RQC). May mediate the addition of alanine residues (Ala tailing) to incompletely synthesized nascent chains from stalled ribosomes, leading to their degradation.UniRule annotation
GO - Molecular functioni
- ribosomal large subunit binding Source: UniProtKB-UniRule
- tRNA binding Source: UniProtKB-UniRule
GO - Biological processi
- rescue of stalled ribosome Source: UniProtKB-UniRule
Keywordsi
Molecular function | RNA-binding, tRNA-bindingUniRule annotation |
Biological process | Protein biosynthesisUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Archaeal Rqc2 homolog aRqcHUniRule annotationShort name: aRqcHUniRule annotation |
Gene namesi | Name:rqcHUniRule annotation ORF Names:EKH57_02770Imported |
Organismi | Halorubrum sp. BOL3-1Imported |
Taxonomic identifieri | 2497325 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Haloferacales › Halorubraceae › Halorubrum › unclassified Halorubrum |
Proteomesi |
|
Interactioni
Subunit structurei
Associates with stalled 50S ribosomal subunits.
UniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 541 – 657 | NFACT-R_1InterPro annotationAdd BLAST | 117 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 241 – 275 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 487 – 527 | DisorderedSequence analysisAdd BLAST | 41 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 335 – 369 | UniRule annotationAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 253 – 269 | AcidicSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the NEMF family.UniRule annotation
Keywords - Domaini
Coiled coilUniRule annotationFamily and domain databases
HAMAPi | MF_00844_A, RqcH_A, 1 hit |
InterProi | View protein in InterPro IPR008532, NFACT_RNA-bd IPR010979, Ribosomal_S13-like_H2TH IPR043681, RqcH_archaeal |
Pfami | View protein in Pfam PF05670, NFACT-R_1, 1 hit |
SUPFAMi | SSF46946, SSF46946, 1 hit |
i Sequence
Sequence statusi: Complete.
A0A410TLU6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDQKRELSSV DLAALVTELN RYEGAKVDKA YLYDDDLLRL KLRDFDRGRV
60 70 80 90 100
ELMIEVGDVK RAHAADPDNV ADAPGRPPNF AKMLRNRMSG ADFAGVEQYE
110 120 130 140 150
FDRILTFEFE REDQNTTIVA ELFGQGNVAA LDETGEVVGS LSTVRLKSRT
160 170 180 190 200
VAPGAQYEYP ASRLNPLDVS RGGFDRHMRE SDSDVVRTLA TQLNLGGLYA
210 220 230 240 250
EEVCTRADVE KETPIEEVTD DQLRALHDAL SRIDERVRSG NIDPRVYEES
260 270 280 290 300
VDGDGNADGD GDGDEDGNGD ADAEPRVVDV TPFPLAEHED LPSVGFDSFN
310 320 330 340 350
TAVDEYFHRL EREGTADDES PADASPSRPE FEEEIAKQER IIEQQQGAIE
360 370 380 390 400
GFEEQAQAER ERAELLYANY DLVDDVLSTV REAREDEVPW AEIQKTLSAG
410 420 430 440 450
AERGIPAAEA VVDVDGEDGT VTVELARETG DETGGGNGGD ETVRIELDAS
460 470 480 490 500
EGVEVNADRL YQEAKRVEEK KTGAIAAIES TREELAAVEE RKAEWEATDA
510 520 530 540 550
ADGGSAGDGD EGGEDDEEHE ADWLSRSSIP IRSPDDWYDR FRWFHTSTGY
560 570 580 590 600
LVIGGRNADQ NEELVKKYMS KHDRFFHTQA HGGPVTILKA SGPSESAEPV
610 620 630 640 650
DFSEETLREA AQFAVSYSSV WKDGRGAGDA YMVEPDQVSK TPESGEYVEK
660 670 680 690 700
GSFVIRGDRT YLEDAPCRIA VGVQCEPITR AIGGPPSAIV DRAAAHVTFE
710 720 730 740
PGMYAQNDAA MMAYRNLKER FTDQSFVRKV ASADRLQEFL PSGGSDIAD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP034692 Genomic DNA Translation: QAU11762.1 |
Genome annotation databases
KEGGi | halb:EKH57_02770 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP034692 Genomic DNA Translation: QAU11762.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
KEGGi | halb:EKH57_02770 |
Family and domain databases
HAMAPi | MF_00844_A, RqcH_A, 1 hit |
InterProi | View protein in InterPro IPR008532, NFACT_RNA-bd IPR010979, Ribosomal_S13-like_H2TH IPR043681, RqcH_archaeal |
Pfami | View protein in Pfam PF05670, NFACT-R_1, 1 hit |
SUPFAMi | SSF46946, SSF46946, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A410TLU6_9EURY | |
Accessioni | A0A410TLU6Primary (citable) accession number: A0A410TLU6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 8, 2019 |
Last sequence update: | May 8, 2019 | |
Last modified: | December 2, 2020 | |
This is version 8 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |