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1 to 25 of 82  Show
  1. 1
    "Identification and characterization of novel alternative splice variants of L-dopa decarboxylase (DDC) in human cancer cells, using Next Generation Sequencing."
    Adamopoulos P.G., Kontos C.K., Fragoulis E.G., Scorilas A.
    Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).
  2. 2
    "Neuronal promoter of human aromatic L-amino acid decarboxylase gene directs transgene expression to the adult floor plate and aminergic nuclei induced by the isthmus."
    Chatelin S., Wehrle R., Mercier P., Morello D., Sotelo C., Weber M.J.
    Brain Res. Mol. Brain Res. 97:149-160(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: gene promoter directs transgene expression to the adult floor plate and aminergic nuclei induced by the isthmus.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  3. 3
    "Investigation of two variants in the DOPA decarboxylase gene in patients with autism."
    Lauritsen M.B., Borglum A.D., Betancur C., Philippe A., Kruse T.A., Leboyer M., Ewald H.
    Am. J. Med. Genet. 114:466-470(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: findings suggest that the DDC gene is unlikely to play a major role in the development of autism in our data set.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  4. 4
    "Association study between two variants in the DOPA decarboxylase gene in bipolar and unipolar affective disorder."
    Jahnes E., Muller D.J., Schulze T.G., Windemuth C., Cichon S., Ohlraun S., Fangerau H., Held T., Maier W., Propping P., Nothen M.M., Rietschel M.
    Am. J. Med. Genet. 114:519-522(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); Results do not support an involvement of the 1-bp or 4-bp deletion within the DDC gene in the etiology of affective disorders. [GeneRIF:1644]. Not Associated with PSYCH: bipolar affective disorder; unipolar affective disorder. [GAD:121271]. Not Associated with PSYCH: bipolar disorder. [GAD:121269].
    Source: GeneRIF:1644, GAD:121269, GAD:121271.

    This publication is mapped to 46 other entries.

  5. 5
    "Possible parent-of-origin effect of Dopa decarboxylase in susceptibility to bipolar affective disorder."
    Borglum A.D., Kirov G., Craddock N., Mors O., Muir W., Murray V., McKee I., Collier D.A., Ewald H., Owen M.J., Blackwood D., Kruse T.A.
    Am. J. Med. Genet. B Neuropsychiatr. Genet. 117B:18-22(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: DDC might confer susceptibility to bipolar affective disorder predominantly when paternally transmitted.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  6. 6
    "Cloning and expression of human placental L-Dopa decarboxylase."
    Siaterli M.Z., Vassilacopoulou D., Fragoulis E.G.
    Neurochem. Res. 28:797-803(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: This enzyme is cloned from and expressed in placenta.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  7. 7
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: We report three siblings who showed the clinical phenotype to be caused by aromatic L-amino acid decarboxylase deficiency. Molecular characterization showed a homozygous point mutation (c.387 G-->A) in exon 3.
    Source: GeneRIF:1644.

    This publication is mapped to 45 other entries.

  8. 8
    "No association between polymorphisms in the DDC gene and paranoid schizophrenia in a northern Chinese population."
    Zhang B., Jia Y., Yuan Y., Yu X., Xu Q., Shen Y., Shen Y.
    Psychiatr. Genet. 14:161-163(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: Not Associated with PSYCH: schizophrenia. [GAD:121270]. Polymorphisms studied do not play a major role in paranoid schizophrenia pathogenesis in the population investigated; Observational study of gene-disease association. (HuGE Navigator). [GeneRIF:1644].
    Source: GeneRIF:1644, GAD:121270.

    This publication is mapped to 46 other entries.

  9. 9
    "Molecular detection of dopamine decarboxylase expression by means of reverse transcriptase and polymerase chain reaction in bone marrow and peripheral blood: utility as a tumor marker for neuroblastoma."
    Bozzi F., Luksch R., Collini P., Gambirasio F., Barzano E., Polastri D., Podda M., Brando B., Fossati-Bellani F.
    Diagn. Mol. Pathol. 13:135-143(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech, Expression.
    Annotation: dopamine decarboxylase mRNA in neuroblastoma patients could be a potential marker for minimal residual disease.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  10. 10
    "Identification and characterization of a novel form of the human L-dopa decarboxylase mRNA."
    Vassilacopoulou D.S., Sideris D.C., Vassiliou A.G., Fragoulis E.G.
    Neurochem. Res. 29:1817-1823(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Detection of a new alternative splicing event within the coding region of the human dopa decarboxylase (DDC) mRNA suggests that the single copy human DDC gene undergoes complex processing leading to the formation of multiple mRNA isoforms.
    Source: GeneRIF:1644.

    This publication is mapped to 45 other entries.

  11. 11
    "Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence."
    Ma J.Z., Beuten J., Payne T.J., Dupont R.T., Elston R.C., Li M.D.
    Hum. Mol. Genet. 14:1691-1698(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Single nucleotide polymorphisms in the dopa decarboxylase gene is associated with nicotine dependence.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  12. 12
    "Congenital hyperinsulinism: pancreatic [18F]fluoro-L-dihydroxyphenylalanine (DOPA) positron emission tomography and immunohistochemistry study of DOPA decarboxylase and insulin secretion."
    de Lonlay P., Simon-Carre A., Ribeiro M.J., Boddaert N., Giurgea I., Laborde K., Bellanne-Chantelot C., Verkarre V., Polak M., Rahier J., Syrota A., Seidenwurm D., Nihoul-Fekete C., Robert J.J., Brunelle F., Jaubert F.
    J. Clin. Endocrinol. Metab. 91:933-940(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Immunohistochemical detection of DOPA decarboxylase shows diffuse staining of Langerhans islets in congenital hyperinsulinism.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  13. 13
    "Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans."
    Yu Y., Panhuysen C., Kranzler H.R., Hesselbrock V., Rounsaville B., Weiss R., Brady K., Farrer L.A., Gelernter J.
    Hum. Mol. Genet. 15:2192-2199(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: Associated with CHEMDEPENDENCY: nicotine dependence smoking behavior. [GAD:146669]. association of alleles and haplotypes at the DOPA decarboxylase (DDC) locus with the DSM-IV diagnosis of nicotine dependence; Observational study of gene-disease association. (HuGE Navigator). [GeneRIF:1644].
    Source: GAD:146669, GeneRIF:1644.

    This publication is mapped to 46 other entries.

  14. 14
    "DOPA decarboxylase gene is associated with nicotine dependence."
    Zhang H., Ye Y., Wang X., Gelernter J., Ma J.Z., Li M.D.
    Pharmacogenomics 7:1159-1166(2006) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator); Association of the DOPA decarboxylase (DDC) gene on chromosome 7p11 with measures of nicotine dependence.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  15. 15
    Category: Function, Sequences.
    Annotation: Autoantibodies to the COOH-terminal region induce a significant inhibition of enzymatic activity.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  16. 16
    "Unusually mild phenotype of AADC deficiency in 2 siblings."
    Tay S.K., Poh K.S., Hyland K., Pang Y.W., Ong H.T., Low P.S., Goh D.L.
    Mol. Genet. Metab. 91:374-378(2007) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Expands clinical spectrum of AADC deficiency and contributes to the knowledge of the genotype and phenotype correlation for the DDC gene.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  17. 17
    "Exploration of 19 serotoninergic candidate genes in adults and children with attention-deficit/hyperactivity disorder identifies association for 5HT2A, DDC and MAOB."
    Ribases M., Ramos-Quiroga J.A., Hervas A., Bosch R., Bielsa A., Gastaminza X., Artigas J., Rodriguez-Ben S., Estivill X., Casas M., Cormand B., Bayes M.
    Mol. Psychiatry 14:71-85(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech.
    Annotation: The DDC gene was strongly associated with both adulthood (P=0.00053; odds ratio (OR)=2.17) and childhood ADHD (P=0.0017; OR=1.90).
    Source: GeneRIF:1644.

    This publication is mapped to 55 other entries.

  18. 18
    Category: Function.
    Annotation: study does not support the involvement of tyrosine hydroxylase gene variants as major contributors to suicide whereas dopa decarboxylase variants could mediate some features related to suicide and be involved in violent suicidal behavior; Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:1644.

    This publication is mapped to 62 other entries.

  19. 19
    "Genomic imprinting of Dopa decarboxylase in heart and reciprocal allelic expression with neighboring Grb10."
    Menheniott T.R., Woodfine K., Schulz R., Wood A.J., Monk D., Giraud A.S., Baldwin H.S., Moore G.E., Oakey R.J.
    Mol. Cell. Biol. 28:386-396(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: analysis of Ddc redefines the imprinted Grb10 domain on mouse proximal chromosome 11 and identifies Ddc_exon1a as the first example of a heart-specific imprinted gene.
    Source: GeneRIF:1644.

    This publication is mapped to 61 other entries.

  20. 20
    Category: Function, Pathology & Biotech.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:1644.

    This publication is mapped to 67 other entries.

  21. 21
    "Worldwide genetic variation in dopamine and serotonin pathway genes: implications for association studies."
    Gardner M., Bertranpetit J., Comas D.
    Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B:1070-1075(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Pathology & Biotech, Sequences.
    Annotation: Observational study of genotype prevalence. (HuGE Navigator).
    Source: GeneRIF:1644.

    This publication is mapped to 224 other entries.

  22. 22
    "Aromatic L-amino acid decarboxylase deficiency in Taiwan."
    Lee H.F., Tsai C.R., Chi C.S., Chang T.M., Lee H.J.
    Eur. J. Paediatr. Neurol. 13:135-140(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech, Sequences.
    Annotation: Three different mutations were identified in the DDC gene including two novel mutations 1303 C>T and 1367ins A and one IVS 6+4 A>T mutation in patients with AADC deficiency in Taiwan.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  23. 23
    "Expression analysis and clinical utility of L-Dopa decarboxylase (DDC) in prostate cancer."
    Avgeris M., Koutalellis G., Fragoulis E.G., Scorilas A.
    Clin. Biochem. 41:1140-1149(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: These data reveal the potential of DDC expression at the mRNA level as a novel biomarker in prostate cancer.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

  24. 24
    "mRNAs of tyrosine hydroxylase and dopa decarboxylase but not of GD2 synthase are specific for neuroblastoma minimal disease and predicts outcome for children with high-risk disease when measured at diagnosis."
    Trager C., Vernby A., Kullman A., Ora I., Kogner P., Kagedal B.
    Int. J. Cancer 123:2849-2855(2008) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Sequences.
    Annotation: Hhigh expression of DDC both in peripheral blood and bone marrow corresponds to metastatic neuroblastoma at diagnosis residual disease and poor outcome.
    Source: GeneRIF:1644.

    This publication is mapped to 62 other entries.

  25. 25
    "Expression of enzymatically active L-DOPA decarboxylase in human peripheral leukocytes."
    Kokkinou I., Nikolouzou E., Hatzimanolis A., Fragoulis E.G., Vassilacopoulou D.
    Blood Cells Mol. Dis. 42:92-98(2009) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: The expression of enzymatically active DDC in human leukocytes could indicate a cross-talk between the nervous and the immune systems and raises new questions about the regulatory role of DDC in immune responses.
    Source: GeneRIF:1644.

    This publication is mapped to 46 other entries.

1 to 25 of 82  Show
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