Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 3 (05 Jun 2019)
Sequence version 1 (10 Apr 2019)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

E3 ubiquitin-protein ligase MYCBP2 isoform X3

Gene

MYCBP2

Organism
Ursus arctos horribilis
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
E3 ubiquitin-protein ligase MYCBP2 isoform X3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MYCBP2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiUrsus arctos horribilisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri116960 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaUrsidaeUrsus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000286642 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati601 – 656RCC1PROSITE-ProRule annotationAdd BLAST56
Repeati959 – 1009RCC1PROSITE-ProRule annotationAdd BLAST51
Repeati1010 – 1067RCC1PROSITE-ProRule annotationAdd BLAST58
Repeati2336 – 2434FilaminPROSITE-ProRule annotationAdd BLAST99
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3718 – 3896DOCInterPro annotationAdd BLAST179
Domaini4428 – 4479RING-typeInterPro annotationAdd BLAST52

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni87 – 127DisorderedSequence analysisAdd BLAST41
Regioni170 – 192DisorderedSequence analysisAdd BLAST23
Regioni609 – 628DisorderedSequence analysisAdd BLAST20
Regioni898 – 928DisorderedSequence analysisAdd BLAST31
Regioni2710 – 2931DisorderedSequence analysisAdd BLAST222
Regioni2979 – 3020DisorderedSequence analysisAdd BLAST42
Regioni3605 – 3629DisorderedSequence analysisAdd BLAST25
Regioni3915 – 3936DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3193 – 3216Sequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi102 – 121BasicSequence analysisAdd BLAST20
Compositional biasi614 – 628PolyampholyteSequence analysisAdd BLAST15
Compositional biasi908 – 924PolyampholyteSequence analysisAdd BLAST17
Compositional biasi2714 – 2735PolarSequence analysisAdd BLAST22
Compositional biasi2736 – 2757PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2783 – 2856PolarSequence analysisAdd BLAST74
Compositional biasi2860 – 2890PolyampholyteSequence analysisAdd BLAST31
Compositional biasi3919 – 3933PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.30, 2 hits
2.60.120.260, 1 hit
2.60.120.820, 2 hits
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004939 APC_su10/DOC_dom
IPR017868 Filamin/ABP280_repeat-like
IPR008979 Galactose-bd-like_sf
IPR014756 Ig_E-set
IPR012983 PHR
IPR038648 PHR_sf
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
IPR003646 SH3-like_bac-type
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03256 ANAPC10, 1 hit
PF08005 PHR, 2 hits
PF00415 RCC1, 1 hit
PF08239 SH3_3, 1 hit
PF13639 zf-RING_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00633 RCCNDNSATION

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01337 APC10, 1 hit
SM00184 RING, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49785 SSF49785, 1 hit
SSF50985 SSF50985, 1 hit
SSF81296 SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51284 DOC, 1 hit
PS50194 FILAMIN_REPEAT, 1 hit
PS00626 RCC1_2, 2 hits
PS50012 RCC1_3, 3 hits
PS50089 ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A3Q7WFU2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMMCSATASP AAASSGPGGD GFFPAATISS SPAPGALFMP VPEGSVAAAG
60 70 80 90 100
LGLGLPAADS RGHYQLLLSG RALADRYRRI YTAALSDRDQ GGSSAGHPAS
110 120 130 140 150
RNKKILNKKK LKRKQKSKSK VKTRSKSENL ESTVIIPDIK LHSNPSAFNI
160 170 180 190 200
YCNVRHCVLE WQKKETSLAA ASKNSVQSGE SDSDEEEESK EPPIKLPKII
210 220 230 240 250
EVGLCEVFEL IKETRFSHPS LCLRSLQALL NVLQGQQPEG LQSEPPEVLE
260 270 280 290 300
SLFQLLLEIT VRSTGMNDST GQSLTALSCA CLFSLVASWG ETGRTLQAIS
310 320 330 340 350
AILTNNGSHA CQTIQVPTIL NSLQRSVQAV LVGKIQIQDW FSNGIKKAAL
360 370 380 390 400
MHKWPLKEIT VDEDDQCLLQ NDGFFLYLLC KDGLYKIGSG YSGTVRGHIY
410 420 430 440 450
NSTSRIRNRK EKKSWLGYAQ GYLLYRDVNN HSMTAIRISP ETLEQDGTVM
460 470 480 490 500
LPDCHTEGQN ILFTDGEYIN QIAASRDDGF VVRIFATSTE PVLQQELQLK
510 520 530 540 550
LARKCLHACG ISLFDLEKDL HIISTGFDEE SAILGAGREF ALMKTASGKI
560 570 580 590 600
YYTGKYQSLG IKQGGPSAGK WVELPITKSP KIVHFSVGHD GSHALLVAED
610 620 630 640 650
GSIFFTGSAS KGEDGESTKS RRQSKPYKPK KIIKMEGKIV VYTACNNGSS
660 670 680 690 700
SVISKDGELY MFGKDAIYSD SSSLVTDLKG HFVTQVAMGK AHTCVLMKNG
710 720 730 740 750
EVWTFGVNNK GQCGRDTGAM NQGGKGFGVE NMATAMDEDL EEELDEKDEK
760 770 780 790 800
SMMCPPGMHK WKLEQCMVCT VCGDCTGYGA SCVSSGRPDR VPGGICGCGS
810 820 830 840 850
GESGCAVCGC CKACARELDG QEARQRGILD AVKEMIPLDL LLAVPVPGVN
860 870 880 890 900
IEEHLQLRQE EKRQRVIRRH RLEEGRGPLV FAGPIFMNHR EQALARLRSH
910 920 930 940 950
PAQLKHKRDK HKDGSGERGE KDASKITTYP PGSVRFDCEL RAVQVSCGFH
960 970 980 990 1000
HSVVLMENGD VYTFGYGQHG QLGHGDVNSR GCPTLVQALP GPSTQVTAGS
1010 1020 1030 1040 1050
NHTAVLLMDG QVFTFGSFSK GQLGRPILDV PYWNAKPAPM PNIGSKYGRK
1060 1070 1080 1090 1100
ATWIGASGDQ TFLRIDEALI NSHVLATSEI FASKHIIGLV PASISEPPPF
1110 1120 1130 1140 1150
KCLLINKVDG SCKTFNDSEQ EDLQGFGVCL DPVYDVIWRF RPNTRELWCY
1160 1170 1180 1190 1200
NAVVADARLP SAADMQSRCS ILSPELALPT GSRALTTRSH AALHILGCLD
1210 1220 1230 1240 1250
TLAAMQDLKM GVASTEEETQ AVMKVYSKED YSVVNRFESH GGGWGYSAHS
1260 1270 1280 1290 1300
VEAIRFSADT DILLGGLGLF GGRGEYTAKI KLFELGPDGG DHETDGDLLA
1310 1320 1330 1340 1350
ETDVLAYDCA AREKYAMMFD EPVLLQAGWW YVAWARVSGP SSDCGSHGQA
1360 1370 1380 1390 1400
SITTDDGVVF QFKSSKKSNN GTDVNAGQIP QLLYRLPTSD GSASKGKQQT
1410 1420 1430 1440 1450
SEPVHILKRS FARTVSVECF ESLLSILHWS WTTLVLGVEE LRGLKGFQFT
1460 1470 1480 1490 1500
ATLLDLERLR FVGTCCLRLL RVYTCEIYPV SATGKAVVEE TSKLAECIGK
1510 1520 1530 1540 1550
TRTLLRKILS EGVDHCMVKL DNDPQGYLSQ PLSLLEAVLQ ECHNTFTACF
1560 1570 1580 1590 1600
HSFYPTPALQ WACLCDLLNC LDQDIQEANF KTSSSRLLAA VMSALCHTSV
1610 1620 1630 1640 1650
KLTSIFPIAY DGEVLLRSIV KQVSTENDST LVHRFPLLVA HMEKLSQSEE
1660 1670 1680 1690 1700
NISGMTSFRE VLEKMLVIVV LPVRNSLRRE NELFSSHLVS NTCGLLASIV
1710 1720 1730 1740 1750
SELTASALGS EVDGLNSLHS VKASANRFTK TSQGRSWNTG NGSPDAICFS
1760 1770 1780 1790 1800
VDKPGIVVVG FSVYGGGGIH EYELEVLVDD SEHVGDSTHS HRWTSLELVK
1810 1820 1830 1840 1850
GTYTTDDSPS DIAEIRLDKV VPLKENVKYA VRLRNYGSRT ANGDGGMTTV
1860 1870 1880 1890 1900
QCPDGVTFTF STCSLSSNGT NQTRGQIPQI LYYRSEFDGD LQSQLLSKAN
1910 1920 1930 1940 1950
EEDKNCSRAL SVVSTVVRAA KDLLHRALAV DADDIPELLS SSSLFSMLLP
1960 1970 1980 1990 2000
LIIAYIGPVA AAIPKVAVEV FGLVQQLLPS VAILNQKYAP PAFNPNQSTD
2010 2020 2030 2040 2050
STTGNQPEQG LSACTTSNHY AVIESEHPYK PACVMHYKVT FPECVRWMTI
2060 2070 2080 2090 2100
EFDPQCGTAQ SEDVLRLLIP VRTVQNSGYG PKLTSVLENL NSWIELKKFS
2110 2120 2130 2140 2150
GSSGWPTMVL VLPGNEALFS LETASDYVKD DKASFYGFKC FAIGYEFSPG
2160 2170 2180 2190 2200
PDEGVIQLEK ELANLGGVCA AALMKKDLAL PIGNELEEDL EILEEAALQV
2210 2220 2230 2240 2250
CKTHSGILGK GLALSHSPTI LEALEGNLPL QIQSNEQSFL DDFIACVPGS
2260 2270 2280 2290 2300
SGGRLARWLQ PDSYADPQKT SLILNKDDIR CGWPTTITVQ TKDQYGDVVH
2310 2320 2330 2340 2350
VPNMKVEVKA VPVSQKKTSL QQEQVKKPQR IPGSPAVAAA PSNTDMTFGG
2360 2370 2380 2390 2400
LASPKLDVSY EPMIVKEARY IAITMMKVYE NYSFEELRFA SPTPKRPSEN
2410 2420 2430 2440 2450
MLIRVNNDGT YCANWTPGAI GLYTIHVTID GIEIDAGLEV KVKDPPKGMI
2460 2470 2480 2490 2500
PPGTQLVKPK TEPQPNKVRK FVAKDSAGLR IRSHPSLQSE QIGIVKVNGT
2510 2520 2530 2540 2550
ITFIDEIHND DGVWLRLNDE TIKKYVPNMN GYTEAWCLSF NQHLGKSLLV
2560 2570 2580 2590 2600
PVDEPKTNTD DFFKDINSCC PQEATMQEQE MPFLRGGPGM YKVVKTGPSG
2610 2620 2630 2640 2650
HNIRSCPNLR GIPIGMLVLG NKVKAVGEVT NSEGAWVQLD KNSMVEFCES
2660 2670 2680 2690 2700
DEGEAWSLAR DRGGNQYLRH EDEQVLLDQN SQTPPPSPFS VQAFNKGASC
2710 2720 2730 2740 2750
SAQGFDYGLG NNKGDRGTIS TSSRPVSTSG KSELSSKHSR SLKPDGRMSR
2760 2770 2780 2790 2800
TTVDQKKPRG TEGLSASESL MLKSDAAKLR SDSHSRSLSP NHNTLQTLKS
2810 2820 2830 2840 2850
DGRMSSSFRA ESPGPGSRSS SPKPKTLPAN RSSPSGASSP RSSSPHDKNL
2860 2870 2880 2890 2900
PQKSTAPVKT KLDPPRERSK SDSYTLDPDT LRKKKMPLTE PLRGRSTSPK
2910 2920 2930 2940 2950
PKPVPKDSKD SPGSENRAPS PHVVQENLHS EVVEVCTSST LKTNSLTDST
2960 2970 2980 2990 3000
CDESSEFKSV DESSNKVHFS IGKAPLKDEQ EMRASPKISR KCANRHTRPK
3010 3020 3030 3040 3050
KEKSSFLFKG DGSKPLEPAK QAMSPSVAEC ARAVFASFLW HEGIVHDAMA
3060 3070 3080 3090 3100
CSSFLKFNPE LSKEHAPIRN SLNSQQPTEE KETKLKNRHS LEISSALNMF
3110 3120 3130 3140 3150
NIAPHGPDIS KMGSINKNKV LSMLKEPPLH EKCEDGKTEA TFEMSMHHPM
3160 3170 3180 3190 3200
KSKSPLPLTL QHLVAFWEDI SLATIKAASQ NMIFPSPGSC AVLKKKECEK
3210 3220 3230 3240 3250
ENKKAKKDKK KKEKTEVRPR GNLFGEMAQL AVGGPEKDTI CELCGESHPY
3260 3270 3280 3290 3300
PVTYHMRQAH PGCGRYAGGQ GYNSIGHFCG GWAGNCGDGG IGGSTWYLVC
3310 3320 3330 3340 3350
DRCREKYLRE KQAAAREKVK QSRRKPMQVK TPRALPTMEA HQVIKANALF
3360 3370 3380 3390 3400
LLSLSSAAEP SILCYHPAKP FQSHLPSVKE GISEDLPVKM PCLYLQTLAR
3410 3420 3430 3440 3450
HHHENFVGYQ DDNLFQDEMR YLRSTSVPAP YISVTPDASP NVFEEPESNM
3460 3470 3480 3490 3500
KSMPPSLETS PITDTDLAKR TVFQRSYSVV ASEYDKQHSI LPARVKAIPR
3510 3520 3530 3540 3550
RRVNSGDTEV GSSLLRHPSP ELSRLISAHS SLSKGERNFQ WPVLAFVIQH
3560 3570 3580 3590 3600
HDLEGLEIAM KQALRKSACR VFAMEAFNWL LCNVIQTTSL HDILWHFVAS
3610 3620 3630 3640 3650
LTPAPVEPEE EEDEENKTNK ENAEQEKDTR VCEHPLSDIV IAGEAAHPLP
3660 3670 3680 3690 3700
HTFHRLLQTI SDLMMSLPSG SSLQQMALRC WSLKFKQSDH QFLHQSNVFH
3710 3720 3730 3740 3750
HINNILSKSD DGDSEESFSI SIQSGFEAMS QELCIVMCLK DLTSIVDIKT
3760 3770 3780 3790 3800
SSRPAMIGSL TDGSTETFWE SGDEDKNKTK NITINCVKGI NARYVSVHVD
3810 3820 3830 3840 3850
NSRDLGNKVT SMTFLTGKAV EDLCRIKQVD LDSRHIGWVT SELPGGDNHI
3860 3870 3880 3890 3900
IKIELKGPEN TLRVRQVKVL GWKDGESTKI AGQISASVAQ QRNCEAETLR
3910 3920 3930 3940 3950
VFRLITSQVF GKLISGDAEP TPEQEEKALL SSPEGEEKVY NATSDADLKE
3960 3970 3980 3990 4000
HMVGIIFSRS KLTNLQKQVC AHIVQAIRME ATRVREEWEH AISSKENANS
4010 4020 4030 4040 4050
QPNDEDASSD AYCFELLSMV LALSGSNVGR QYLAQQLTLL QDLFSLLHTA
4060 4070 4080 4090 4100
SPRVQRQVTS LLRRVLPEVT PNRLASIIGV KALPPADISD IIHSTEKGDW
4110 4120 4130 4140 4150
NKLGILDMFL GCIAKALTVQ LKAKGTTITG TAGTTVGKGV TTVTLPMIFN
4160 4170 4180 4190 4200
SSYVRRGESH WWMKGSTPTQ ISEIIIKLIK DMAAGHLSEA WSRVTKNAIA
4210 4220 4230 4240 4250
ETIIALTKME EEFRSPVRCI ATTRLWLALA SLCVLDQDHV DRLSSGRWMG
4260 4270 4280 4290 4300
KDGQQKQMPM CDNHDDGETA AIILCNVCGN LCTDCDRFLH LHRRTKTHQR
4310 4320 4330 4340 4350
QVFKEEEEAI KVDLHEGCGR TKLFWLMALA DSKTMKAMVE FREHTGKPTT
4360 4370 4380 4390 4400
SSSEACRFCG SRSGTELSAV GSVCSDADCQ DYAKIACSKT HPCGHPCGGV
4410 4420 4430 4440 4450
KNEEHCLPCL HGCDKSATTL KQDADDMCMI CFTEALSAAP AIQLDCSHVF
4460 4470 4480 4490 4500
HLQCCRRVLE NRWLGPRITF GFISCPICKN KINHIVLKDL LDPIKELYED
4510 4520 4530 4540 4550
VRRKALMRLE YEGLHKSEAI TTPGVRFYND PAGYAMNRYA YYVCYKCRKA
4560 4570 4580 4590 4600
YFGGEARCDA EAGQGDDYDP RELICGACSD VSRAQMCPKH GTDFLEYKCR
4610 4620 4630 4640 4650
YCCSVAVFFC FGTTHFCNAC HDDFQRMTSI PKEELPHCPA GPKGKQLEGT
4660 4670
ECPLHVVHPP TGEEFALGCG VCRNAHTF
Length:4,678
Mass (Da):513,737
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i37163DD61382B9F1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q7UL31A0A3Q7UL31_URSAR
E3 ubiquitin-protein ligase MYCBP2 ...
MYCBP2
4,752Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7VAN1A0A3Q7VAN1_URSAR
E3 ubiquitin-protein ligase MYCBP2 ...
MYCBP2
4,755Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7VJK0A0A3Q7VJK0_URSAR
E3 ubiquitin-protein ligase MYCBP2 ...
MYCBP2
3,808Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_026349217.1, XM_026493432.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_026349217.1, XM_026493432.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.130.10.30, 2 hits
2.60.120.260, 1 hit
2.60.120.820, 2 hits
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR004939 APC_su10/DOC_dom
IPR017868 Filamin/ABP280_repeat-like
IPR008979 Galactose-bd-like_sf
IPR014756 Ig_E-set
IPR012983 PHR
IPR038648 PHR_sf
IPR009091 RCC1/BLIP-II
IPR000408 Reg_chr_condens
IPR003646 SH3-like_bac-type
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF03256 ANAPC10, 1 hit
PF08005 PHR, 2 hits
PF00415 RCC1, 1 hit
PF08239 SH3_3, 1 hit
PF13639 zf-RING_2, 1 hit
PRINTSiPR00633 RCCNDNSATION
SMARTiView protein in SMART
SM01337 APC10, 1 hit
SM00184 RING, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
SSF50985 SSF50985, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS51284 DOC, 1 hit
PS50194 FILAMIN_REPEAT, 1 hit
PS00626 RCC1_2, 2 hits
PS50012 RCC1_3, 3 hits
PS50089 ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q7WFU2_URSAR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q7WFU2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: June 5, 2019
This is version 3 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again