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Entry version 8 (10 Feb 2021)
Sequence version 1 (10 Apr 2019)
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Protein
Submitted name:

kinectin isoform X3

Gene

KTN1

Organism
Vulpes vulpes (Red fox)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
kinectin isoform X3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KTN1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiVulpes vulpes (Red fox)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9627 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeVulpes
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000286640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei170 – 191HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini191 – 328Rib_recp_KP_regInterPro annotationAdd BLAST138

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni15 – 37DisorderedSequence analysisAdd BLAST23
Regioni60 – 82DisorderedSequence analysisAdd BLAST23
Regioni211 – 240DisorderedSequence analysisAdd BLAST30
Regioni270 – 380DisorderedSequence analysisAdd BLAST111

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili503 – 530Sequence analysisAdd BLAST28
Coiled coili535 – 555Sequence analysisAdd BLAST21
Coiled coili567 – 594Sequence analysisAdd BLAST28
Coiled coili603 – 658Sequence analysisAdd BLAST56
Coiled coili726 – 753Sequence analysisAdd BLAST28
Coiled coili764 – 784Sequence analysisAdd BLAST21
Coiled coili813 – 882Sequence analysisAdd BLAST70
Coiled coili892 – 915Sequence analysisAdd BLAST24
Coiled coili920 – 947Sequence analysisAdd BLAST28
Coiled coili958 – 1013Sequence analysisAdd BLAST56
Coiled coili1024 – 1051Sequence analysisAdd BLAST28
Coiled coili1059 – 1145Sequence analysisAdd BLAST87
Coiled coili1156 – 1197Sequence analysisAdd BLAST42
Coiled coili1277 – 1325Sequence analysisAdd BLAST49
Coiled coili1337 – 1409Sequence analysisAdd BLAST73
Coiled coili1466 – 1486Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi225 – 240PolyampholyteSequence analysisAdd BLAST16
Compositional biasi282 – 301PolyampholyteSequence analysisAdd BLAST20
Compositional biasi324 – 348PolyampholyteSequence analysisAdd BLAST25
Compositional biasi365 – 380PolyampholyteSequence analysisAdd BLAST16

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024854, Kinectin
IPR007794, Rib_rcpt_KP

The PANTHER Classification System

More...
PANTHERi
PTHR18864, PTHR18864, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05104, Rib_recp_KP_reg, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A3Q7T7G2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLEFGSSLPL RILRGPALPP SQAPSHRRVR VPGSRRGGGW GWESGVRGLG
60 70 80 90 100
ENVWPALETG EVTPSSPRGV CPSSVAPPPP PPPFPTMRFS WRLGISAENQ
110 120 130 140 150
TGSLEKSLGH QTPGVGCAAA HVCPGGACVR RRRAARVAGQ RRPNRVQLQL
160 170 180 190 200
AQVLQNYINK STMEFYESTY FIVLIPSVVI TVIFLFFWLF MKETLYDEVL
210 220 230 240 250
AKQKREQKLI PTKTDKKKAE KKKNKKKEIQ NGNLHESDSE SVPRDFKLSV
260 270 280 290 300
ALAVEDEQVV PIPLNVVETS SSVRERKKKE KKHKPVLEEQ VTKESDVSKI
310 320 330 340 350
PGKKVEPVPV TKQPTPPSEA AASKKKPGQK KSKNGSDDQD KKVETLMAPS
360 370 380 390 400
KKQESLPLQQ ETKQESGSGK KKVSSKKQKA ENVLVDEPLI HATTYIPLMD
410 420 430 440 450
NADSNPVLDK REVIDLIKPD QVEGIQKTGA KKLKTETDKE NAEVKFKDFL
460 470 480 490 500
LSLKTMMFSE DEALCVVDLL KEKSGVIQDA LKRSSKGELT ALVHQLQEKD
510 520 530 540 550
KLLAAVKEDA AVMKDRCKQL TQEMMSEKER SNVVIARMKD RIGTLEKEHN
560 570 580 590 600
VFQNKMHVSY QETQQMQMKF QQVREQMEAE IAHLKQENGI LRDAVSNTTN
610 620 630 640 650
QLESKQSAEL NKLRQDYARL VNELTEKTGK LQQEEVQKKN AEQAVTQLKV
660 670 680 690 700
QLQEAERRWE EVQSYIRKRT AEHEAAQQDL QSKFVAKENE VQSLHSKLTD
710 720 730 740 750
TLVSKQQLEQ RLMQLMESEQ KRVTKEESLQ MQVQDILEQN EALKAQIQQF
760 770 780 790 800
HSQIAAQTSA SVLAEELHKV IAEKDKQIKQ TEDSLANEHD HLTSKEEELK
810 820 830 840 850
DIQNMNFLLK AEVQKLQALA NEQAAAAHEL EKMQKSIHVK DDQIRLLEEQ
860 870 880 890 900
LQCEISNKME EFKILNDQNK ALQLEVQKLQ ILVSEQPNKD VVEQMEKCIQ
910 920 930 940 950
EKDEKLKTVE ELLETGLIQV ATKEEELNAI RTENSSLTKE VQDLKAKQND
960 970 980 990 1000
QVSFASLVEE LKKVIHEKDG KIKSVEELLE AEVLKVANKE KTIQDLKQEI
1010 1020 1030 1040 1050
EALKEEIGNI QLEKAQQLSI TSQIQELQNL LKGKEEQMNT MKTVLEEKEK
1060 1070 1080 1090 1100
DLASRGKWLQ DLQEENESLK THIQEVAQHN LKEACSASRL EELETVLKEK
1110 1120 1130 1140 1150
ENEMKRIETI LKERENDLSS KIKLLQEVQD ENKLFKSEIE QLKQCNYQQA
1160 1170 1180 1190 1200
SSFPPHEELL KVISEREKEI TGLQNELDSL KEAVEHQRKK NNDLREKNWE
1210 1220 1230 1240 1250
AMEALASTEK MLQDKVNKTS KERQQYVEAI ELEAKEVLKK LFPKVSVPPN
1260 1270 1280 1290 1300
LNYGEWLRGF EKKAKEYVAE TSGSEEVKVL EHKLKEADEM HTLLQLECEK
1310 1320 1330 1340 1350
YKSVLAETEG ILQKLQRSVE QEENKWKVKV DESQKTLKQM QLSFTSSEQE
1360 1370 1380 1390 1400
LERLRRENKD IENLRREREH LEMELEKAEI ERSTYVTEVR ELKTQLNETL
1410 1420 1430 1440 1450
TKLRTEQSER QKVAGDLHKA QQSLDLIQSK IVKAAGDTTV IENSDVSPEA
1460 1470 1480 1490
ESSEKETMSV SLNQTVTQLQ QLLQAVNQQL TKEKEHYQVL E
Length:1,491
Mass (Da):170,687
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFD824CB7EA77D411
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O97961KTN1_VULVU
Kinectin
KTN1
1,330Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7TMS6A0A3Q7TMS6_VULVU
kinectin isoform X1
KTN1
1,519Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7S9N6A0A3Q7S9N6_VULVU
kinectin isoform X4
KTN1
1,490Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7SJ65A0A3Q7SJ65_VULVU
kinectin isoform X8
KTN1
1,357Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7SLQ9A0A3Q7SLQ9_VULVU
kinectin isoform X2
KTN1
1,496Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7SLR4A0A3Q7SLR4_VULVU
kinectin isoform X6
KTN1
1,462Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7T7G3A0A3Q7T7G3_VULVU
kinectin isoform X7
KTN1
1,460Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q7TMU2A0A3Q7TMU2_VULVU
kinectin isoform X5
KTN1
1,468Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_025856422.1, XM_026000637.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_025856422.1, XM_026000637.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR024854, Kinectin
IPR007794, Rib_rcpt_KP
PANTHERiPTHR18864, PTHR18864, 1 hit
PfamiView protein in Pfam
PF05104, Rib_recp_KP_reg, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q7T7G2_VULVU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q7T7G2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: February 10, 2021
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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