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UniProtKB - A0A3Q7QBS6 (A0A3Q7QBS6_CALUR)

Entry version 8 (12 Aug 2020)
Sequence version 1 (10 Apr 2019)
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Protein
Submitted name:

zinc finger protein 106 isoform X1

Gene

ZNF106

Organism
Callorhinus ursinus (Northern fur seal)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
zinc finger protein 106 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF106Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCallorhinus ursinus (Northern fur seal)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri34884 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Otariidae › Callorhinus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000286641 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1543 – 1831WD_REPEATS_REGIONInterPro annotationAdd BLAST289
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1583 – 1627WDPROSITE-ProRule annotationAdd BLAST45

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni66 – 176DisorderedSequence analysisAdd BLAST111
Regioni345 – 381DisorderedSequence analysisAdd BLAST37
Regioni410 – 441DisorderedSequence analysisAdd BLAST32
Regioni483 – 528DisorderedSequence analysisAdd BLAST46
Regioni944 – 966DisorderedSequence analysisAdd BLAST23
Regioni978 – 1070DisorderedSequence analysisAdd BLAST93
Regioni1140 – 1170DisorderedSequence analysisAdd BLAST31
Regioni1184 – 1242DisorderedSequence analysisAdd BLAST59
Regioni1291 – 1499DisorderedSequence analysisAdd BLAST209
Regioni1518 – 1543DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi92 – 109PolyampholyteSequence analysisAdd BLAST18
Compositional biasi120 – 136PolyampholyteSequence analysisAdd BLAST17
Compositional biasi149 – 165PolyampholyteSequence analysisAdd BLAST17
Compositional biasi488 – 508PolarSequence analysisAdd BLAST21
Compositional biasi978 – 1032PolarSequence analysisAdd BLAST55
Compositional biasi1187 – 1224PolarSequence analysisAdd BLAST38
Compositional biasi1318 – 1332PolarSequence analysisAdd BLAST15
Compositional biasi1407 – 1422PolarSequence analysisAdd BLAST16
Compositional biasi1423 – 1437PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1456 – 1470PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1471 – 1499PolarSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

WD repeatPROSITE-ProRule annotationARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR018391, PQQ_beta_propeller_repeat
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type

The PANTHER Classification System

More...PANTHERi		PTHR14435, PTHR14435, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00400, WD40, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00564, PQQ, 4 hits
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3Q7QBS6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVRERKCILC HIVYSSKKEM DEHMRSMLHH RELENLKGRD SSHECRVCGV 
        60         70         80         90        100
TEVGLSAYAK HISSQLHKDN VDAQDREDDG KGEEEEEDYF DKELVQLIKQ 
       110        120        130        140        150
RKEQSRQEEP SNSSQEISSD DRRPQWRRED RIPYQDREGY SQPAWHHRGP 
       160        170        180        190        200
PQRDWKWEKD GFNNNRKNNF PHSLRNNGGP RGCSGWHKGV AGGASTWFHN 
       210        220        230        240        250
HSNSGGGWHS KSGAVDWNPN GTGRNSSWHS EGTGGFSSWH MNSSNGNWKS 
       260        270        280        290        300
SVRSTNSWNY SGPGDKFQPG RNRNSNCQMD DLTMLWNKKS KSNKYNQERY 
       310        320        330        340        350
SWQRQESDKI GTAATYRGPS EGFTADKFPS EGLLSFSFEQ LESKTTKQTD 
       360        370        380        390        400
PIASKMGGKN GSVTRDKLHR WTPYPPQKTL DLQSGMKEVT GNKSEMIDKP 
       410        420        430        440        450
FFDFSLTTAG TPEPQIDETN HSPTLKTQKE THGGSLTHKA PSDCTASYEA 
       460        470        480        490        500
VRDCPVTEKH EQELHLSKMP SLKSALLPIP VTKSVPQKPD LKNPSKNTKT 
       510        520        530        540        550
NSFFPGEHSN PLNKPAMEDS HGSHVTKLRS SCPHVLKGNK STFGTQREPD 
       560        570        580        590        600
ENFSDTLQKA KEVLQCHESL QNPLLGTSKR TRNFAKASRN VEESEKGSLK 
       610        620        630        640        650
IEFQVHTLED ESDGELSDTE KRGSKIGTLG SATTEMLSCS THLTDEKEGD 
       660        670        680        690        700
DQNLKTCRKL STNACNSTIH QKEPELQMTS AASPPSGLLL DLKTSLEDAQ 
       710        720        730        740        750
VDDPVKSHVS YETEGFESAS LDAELQKNDL GQSSGPLLPE LSKLGFPASL 
       760        770        780        790        800
QRDLTRHISL KSKTGAHLPE PNLNSARRIR NISGHRKGET EKESGLKPTL 
       810        820        830        840        850
RQILNASRRN VNWEQVIQQV TKKKQELGKG LPRFGIEMVP LVQNEQEVLD 
       860        870        880        890        900
LDGEPDLSNL EGFQWEGISI SSSPGLARKR SLSESSVIMD RAPSVYSFFS 
       910        920        930        940        950
EEGTGKENEP QQIFSPSNSL RAAQSQTTTL GLKQEVTPLA ASLRTGERAE 
       960        970        980        990       1000
NVASQRRHSA QLSSDRAIPL MHLAKDLNSQ EGSTPSSENQ NTQESNGEGN 
      1010       1020       1030       1040       1050
SLSSNTSSAL GISSLADAAT DSSCTSGAEQ NDSQSVRKKR RATGDGSSPE 
      1060       1070       1080       1090       1100
LPSLERKNKR RKIKGKKERS QVDQLLNISL REEELSKSLQ CMDNNLLQAR 
      1110       1120       1130       1140       1150
AALQTAYVEV QRLLMLKQQI TMEMSALRTH RIQILQGLQE TYEPSERPDQ 
      1160       1170       1180       1190       1200
VPYSLPRERR NSRSQTSADA TLLPTPFFPV VLEPPSSHMS PSPTGVPLQV 
      1210       1220       1230       1240       1250
TTSPTFQAHG SVPAPDSSVQ IKQEPMSPEH DESVTAVSQG SAGSVSKELL 
      1260       1270       1280       1290       1300
QANRENSDSC PVYPVITATL SLSEVTESFH EPSQELKFSM EQGNTRNRGN 
      1310       1320       1330       1340       1350
APSSQPADLH EEPVKGNSGS EACTSSFPRL SFVSETPLER DPHSPADQPE 
      1360       1370       1380       1390       1400
QQAESTLTSA ETRGNKKKKK LRKKKTLRAA HVPENSDTEQ DVFTAKPVRK 
      1410       1420       1430       1440       1450
VKTGKSTKGG KVTTSTWEDS RTGPEQESVR DEPDSDSSLE VLEIPNPQLE 
      1460       1470       1480       1490       1500
VVAIDSSESG EEKPDSPSKK DIWNSAEQNS LETSRSGCDE VSSTSEIGTR 
      1510       1520       1530       1540       1550
YKDGIPVSVA ETQTVISSIK GSKNSSEISS EPGDDDEPTE GSFEGHQAAV 
      1560       1570       1580       1590       1600
NAIQIFGNLL YTCSADKTVR AYNLVSRKCI GVFEGHTSKV NCLLVTQTSG 
      1610       1620       1630       1640       1650
KNAALYTGSS DHTIRCYNVK TRECVEQLQL EDRVLCLHSR WRILYAGLAN 
      1660       1670       1680       1690       1700
GTVVTFNIKN NKRLEIFECH GPRAVSCLAT AQEGARKLLV VGSYDCTISV 
      1710       1720       1730       1740       1750
RDARNGLLLR TLEGHSKTIL CMKVVNDLVF SGSSDQSVHA HNIHTGELVR 
      1760       1770       1780       1790       1800
IYKGHNHAVT VVNILGKVMV TACLDKFVRV YELQSHDRLQ VYGGHKDMIM 
      1810       1820       1830       1840       1850
CMTIHKSMIY TGCYDGSIQA VRLNLMQNYR CWWHGCALIF GVVDHLKQHL 
      1860       1870       1880       1890 
LTDHTNPNFQ TLKCRWKNCD AFFTARKGSK QDAAGHIERH AEDDSKIDS
Length:1,899
Mass (Da):210,616
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4280FD476DD4BBE8
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_025739657.1, XM_025883872.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_025739657.1, XM_025883872.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR018391, PQQ_beta_propeller_repeat
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type
PANTHERiPTHR14435, PTHR14435, 1 hit
PfamiView protein in Pfam
PF00400, WD40, 1 hit
SMARTiView protein in SMART
SM00564, PQQ, 4 hits
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q7QBS6_CALUR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q7QBS6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: August 12, 2020
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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