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UniProtKB - A0A3Q7HI50 (A0A3Q7HI50_SOLLC)

Entry version 10 (02 Dec 2020)
Sequence version 1 (10 Apr 2019)
Previous versions | rss
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Protein

Pectinesterase

Gene
N/A
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: pectin degradation

This protein is involved in step 1 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.ARBA annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase, Pectinesterase (101261415), Pectinesterase, Pectinesterase (101244818), Pectinesterase (101246061), Pectinesterase 2.1 (PME2.1), Pectinesterase, Pectinesterase (PMEU1), Pectinesterase (101248642), Pectinesterase, Pectinesterase 2.2 (PME2.2), Pectinesterase (101258375), Pectinesterase (LePME1), Pectinesterase 3 (PME3), Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase 1 (PME1.9), Pectinesterase (101255775), Pectinesterase (101260091), Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase (101260282), Pectinesterase (101244677), Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase (101261269), Pectinesterase (101248083), Pectinesterase, Pectinesterase, Pectinesterase (101260787), Pectinesterase, Pectinesterase (101253120), Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase (101260795), Methionine aminopeptidase, Pectinesterase, Pectinesterase, Pectinesterase (101268391), Pectinesterase (101247796), Pectinesterase/pectinesterase inhibitor U1 (PMEU1), Pectinesterase (101260941), Pectinesterase (101260585), Pectinesterase (101247960), Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase (101266668), Pectinesterase (101262904), Pectinesterase (101261266), Pectinesterase, Pectinesterase (101268168), Pectinesterase (101244375), Pectinesterase, Pectinesterase, Pectinesterase (101261743), Pectinesterase (101257682), Pectinesterase, Pectinesterase (109119119), Pectinesterase (101245713), Pectinesterase, Pectinesterase, Pectinesterase (101264501), Pectinesterase (101266973), Pectinesterase, Pectinesterase, Pectinesterase, Pectinesterase
  2. Pectate lyase (778293), Probable pectate lyase P18 (9612), Pectate lyase, Pectate lyase (101257960), Pectate lyase, Pectate lyase, Pectate lyase (101257697), Pectate lyase (101246909), Probable pectate lyase P59 (LAT59), Probable pectate lyase P56 (LAT56), Pectate lyase, Pectate lyase (101260096), Pectate lyase, Pectate lyase (101250914), Pectate lyase (101264933), Pectate lyase (101263458), Pectate lyase (101249735), Pectate lyase, Pectate lyase (101252082), Pectate lyase (101254639), Pectate lyase, Pectate lyase, Pectate lyase (101260911), Pectate lyase (101253459)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei382PROSITE-ProRule annotation1
Active sitei905PROSITE-ProRule annotation1
Active sitei1441PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAspartyl esteraseARBA annotation, Hydrolase
Biological processCell wall biogenesis/degradationARBA annotation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00545;UER00823

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PectinesteraseARBA annotation (EC:3.1.1.11ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSolanum lycopersicum (Tomato) (Lycopersicon esculentum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri4081 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Solanum subgen. Lycopersicon
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000004994 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei21 – 42HelicalSequence analysisAdd BLAST22
Transmembranei538 – 561HelicalSequence analysisAdd BLAST24
Transmembranei1083 – 1108HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Cell wallARBA annotation, Membrane, Secreted

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 192PMEIInterPro annotationAdd BLAST154
Domaini564 – 715PMEIInterPro annotationAdd BLAST152
Domaini1107 – 1251PMEIInterPro annotationAdd BLAST145

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the C-terminal section; belongs to the pectinesterase family.ARBA annotation
In the N-terminal section; belongs to the PMEI family.ARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.140.40, 3 hits
2.160.20.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR035513, Invertase/methylesterase_inhib
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR033131, Pectinesterase_Asp_AS
IPR000070, Pectinesterase_cat
IPR006501, Pectinesterase_inhib_dom
IPR018040, Pectinesterase_Tyr_AS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01095, Pectinesterase, 3 hits
PF04043, PMEI, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00856, PMEI, 3 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF101148, SSF101148, 3 hits
SSF51126, SSF51126, 3 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01614, PME_inhib, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00800, PECTINESTERASE_1, 3 hits
PS00503, PECTINESTERASE_2, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3Q7HI50-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANPQQPLLI KTHKQNPIIS FKILSFVITL FVALFLVAPY QVEIKHSNLC 
        60         70         80         90        100
KTAQDSQLCL SYVSDLISNE IVTTESDGHS ILMKFLVNYV HQMNNAIPVV 
       110        120        130        140        150
RKMKNQINDI RQHGALTDCL ELLDQSVDFA SDSIAAIDKR SRSEHANAQS 
       160        170        180        190        200
WLSGVLTNHV TCLDELDSFT KAMINGTNLE ELISRAKVAL AMLASLTTQD 
       210        220        230        240        250
EDVFMTVLGK MPSWVSSMDR KLMESSGKDI IANAVVAQDG TGDYQTLAEA 
       260        270        280        290        300
VAAAPDKSKT RYVIYVKRGT YKENVEVASN KMNLMIVGDG MYATTITGSL 
       310        320        330        340        350
NVVDGSTTFR SATLAAVGQG FILQDICIQN TAGPAKDQAV ALRVGADMSV 
       360        370        380        390        400
INRCRIDAYQ DTLYAHSQRQ FYRDSYVTGT VDFIFGNAAV VFQKCQLVAR 
       410        420        430        440        450
KPGKYQQNMV TAQGRTDPNQ ATGTSIQFCN IIASSDLEPV LKEFPTYLGR 
       460        470        480        490        500
PWKEYSRTVV MESYLGGLIN PAGWAEWDGD FALKTLYYGE FMNNGPGAGT 
       510        520        530        540        550
SKRVKWPGYH VITDPAKAMP FTVAKLIQGG SWLRSTGVAF KILTFVVTLF 
       560        570        580        590        600
VALFLVVFLV APYQFEIKHS NLCKTAQDSQ LCLSYVSDLI SNEIVTSDSD 
       610        620        630        640        650
GLSILKKFLV YSVHQMNNAI PVVRKIKNQI NDIREQGALT DCLELLDLSV 
       660        670        680        690        700
DLVCDSIAAI DKRSRSEHAN AQSWLSGVLT NHVTCLDELD SFTKAMINGT 
       710        720        730        740        750
NLDELISRAK VALAMLASVT TPNDEVLRPG LGKMPSWVSS RDRKLMESSG 
       760        770        780        790        800
KDIGANAVVA KDGTGKYRTL AEAVAAAPDK SKTRYVIYVK RGTYKENVEV 
       810        820        830        840        850
SSRKMNLMII GDGMYATIIT GSLNVVDGST TFHSATLAAV GKGFILQDIC 
       860        870        880        890        900
IQNTAGPAKH QAVALRVGAD KSVINRCRID AYQDTLYAHS QRQFYRDSYV 
       910        920        930        940        950
TGTIDFIFGN AAVVFQKCQL VARKPGKYQQ NMVTAQGRTD PNQATGTSIQ 
       960        970        980        990       1000
FCDIIASPDL KPVVKEFPTY LGRPWKKYSR TVVMESYLGG LIDPSGWAEW 
      1010       1020       1030       1040       1050
HGDFALKTLY YGEFMNNGPG AGTSKRVKWP GYHVITDPAE AMSFTVAKLI 
      1060       1070       1080       1090       1100
QGGSWLRSTD VAMATPLQPF LTKTHKQNPI IGFNILTFVV TLFVALFLVV 
      1110       1120       1130       1140       1150
FLVAPYQFEI KHSNLCKSAQ GSQLCLSYVS EIVTTESDGV TVLKKFLVKY 
      1160       1170       1180       1190       1200
VHQMNNAIPV VRKIKNQIND IRQHGALTDC LELLDQSVDL VSDSIAAIDK 
      1210       1220       1230       1240       1250
RSRLEHANVQ SWLSGVLTNH VTCLDELTSL STKNGTVLDE LITRAKVALA 
      1260       1270       1280       1290       1300
MLASVTTPND EVLRQGLGKM PYWVSSRDRK LMESSGKDII ANAVVAQDGT 
      1310       1320       1330       1340       1350
GDYQTLAEAV DAAPDKNKTR YVIYVKMGIY KENVVVTKKK MNLMIVGDGM 
      1360       1370       1380       1390       1400
NATIITGSLN VVDGSTTFRS ATLAAVGQGF ILQDLCIQNT AGPEKGQAVA 
      1410       1420       1430       1440       1450
LRVGADMSVI NRCRIDAYQD TLYAHSQRQF YRDSYVTGTV DFIFGNAAVV 
      1460       1470       1480       1490       1500
FQKCQIVARK PNKRQKNMVT AQGRTDPNQA TGTSIQFCDI IASPDLEPVM 
      1510       1520       1530       1540       1550
NEYKTYLGRP WKKHSRTVVM QSYLDGHIDP SGWFEWRGDF ALKTLYYGEY 
      1560       1570       1580       1590       1600
MNNGPGAGTS KRVKWPGYHV ITDPNEAMPF TVAELIQGGS WLNSTSVAYV 

EGLVE
Length:1,605
Mass (Da):176,700
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB2D0D938FE40D52E
GO

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		Solyc07g064190.2.1; Solyc07g064190.2.1; Solyc07g064190.2

Gramene; a comparative resource for plants

More...Gramenei		Solyc07g064190.2.1; Solyc07g064190.2.1; Solyc07g064190.2

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsemblPlantsiSolyc07g064190.2.1; Solyc07g064190.2.1; Solyc07g064190.2
GrameneiSolyc07g064190.2.1; Solyc07g064190.2.1; Solyc07g064190.2

Enzyme and pathway databases

UniPathwayiUPA00545;UER00823

Family and domain databases

Gene3Di1.20.140.40, 3 hits
2.160.20.10, 3 hits
InterProiView protein in InterPro
IPR035513, Invertase/methylesterase_inhib
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR033131, Pectinesterase_Asp_AS
IPR000070, Pectinesterase_cat
IPR006501, Pectinesterase_inhib_dom
IPR018040, Pectinesterase_Tyr_AS
PfamiView protein in Pfam
PF01095, Pectinesterase, 3 hits
PF04043, PMEI, 3 hits
SMARTiView protein in SMART
SM00856, PMEI, 3 hits
SUPFAMiSSF101148, SSF101148, 3 hits
SSF51126, SSF51126, 3 hits
TIGRFAMsiTIGR01614, PME_inhib, 3 hits
PROSITEiView protein in PROSITE
PS00800, PECTINESTERASE_1, 3 hits
PS00503, PECTINESTERASE_2, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q7HI50_SOLLC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q7HI50
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: December 2, 2020
This is version 10 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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