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UniProtKB - A0A3Q3FKF5 (A0A3Q3FKF5_9LABR)

Entry version 8 (10 Feb 2021)
Sequence version 1 (10 Apr 2019)
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Protein

HEAT repeat-containing protein 6

Gene
N/A
Organism
Labrus bergylta (ballan wrasse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
HEAT repeat-containing protein 6ARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLabrus bergylta (ballan wrasse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri56723 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Eupercaria › Labriformes › Labridae › Labrus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261660 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini434 – 614DUF4042InterPro annotationAdd BLAST181

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni323 – 398DisorderedSequence analysisAdd BLAST76
Regioni638 – 677DisorderedSequence analysisAdd BLAST40
Regioni1141 – 1171DisorderedSequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi358 – 381PolyampholyteSequence analysisAdd BLAST24
Compositional biasi638 – 664PolarSequence analysisAdd BLAST27

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016675

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR025283, DUF4042

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13251, DUF4042, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3Q3FKF5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAALTGMSEV STVSRSDVSA YPSVALSAEA APFTPLRMDG WQLGSSSDAE 
        60         70         80         90        100
KQFSRCASKL RGLRGDSAQL REELNILFDQ LLSENYNKTF DPTINIRPEG 
       110        120        130        140        150
VCSLLKHASS LVPLSQEHLV IKFCQLIHHL LNQLKVIMDE HTLDILVKYT 
       160        170        180        190        200
TSALKVCSTW THSDVLLALS TIVYGNGPQC HQHLSNLLRE DGVLLQYSSP 
       210        220        230        240        250
SQSNMELRRV ALNCMANICL RIPGQPPLDD QYRSVYFSVF LKTLQSPKPP 
       260        270        280        290        300
DTDELFYCMV VQAALKGLQC CLSGGKWKFG GGEDLGSVLA LLKRLMFQGA 
       310        320        330        340        350
PGVSVEWPAV LYPATLPQYE GLPASKSAEP EKPAERPKDA ALPGKTSGNK 
       360        370        380        390        400
KRKSRGKGKK TSAEDSRGDD GEEDDKVSAP QKGGGREGGR GNMESFSKPS 
       410        420        430        440        450
ALSLYPSWKK NSSDSEFSDP EGNAQCKLRL YHARVRQGAL HCLLAVVKSI 
       460        470        480        490        500
EKRTLYSFWS SFIPDSPIGG LPPLTLLTII LKDLSPKVRA CALQVLSAML 
       510        520        530        540        550
DGSRQFLAVA EDTASPRTSY TPFSFSLATA VRELHRALSL ALLAETSPQT 
       560        570        580        590        600
LTQVIKCVAY LVANAPYHRL RPGLLSPLWK QMRPYVRHRD ANVRVSVLTL 
       610        620        630        640        650
YGALVTTQAP LPEVRLLLQQ PEGSTSSGLL TPQDSALSWR QRDGVSSPSR 
       660        670        680        690        700
TPGSLSQWGS CTRSPRAPHT PGEEESSPPW LLQLCVSLVT QPREDQSDSE 
       710        720        730        740        750
GAGTGGVSLE PSPVRLEALQ VMSHLVRGYF SLVQTCLRDI GQVSARCLRE 
       760        770        780        790        800
SDPSIQLHGT KLLEELGTGI IQQYRTENKV PESSRVPMSQ VVLFWSEVLS 
       810        820        830        840        850
GPLNAALQNE QHPTLQTSAC ETLSSILPQA FAQLPDKTQL MCITMLLGLT 
       860        870        880        890        900
YSENYLVKTA AVRALGVYIL FPCLREDVMF VADTANTILA ALEDRSPNVR 
       910        920        930        940        950
AKAAWSLGNL TDTLIVNMES VGVDFQEELS DMLLLKMLQA ATRASDDKDR 
       960        970        980        990       1000
VKSNAVRALG NLLHFLRRSQ MTRSAFQRPL EDAVRSLVKT VQSEATMKVR 
      1010       1020       1030       1040       1050
WNACCALGNA FRNPSLPLDS APWSRDAFSA LCNVVTSCKN FKVRIKSAAA 
      1060       1070       1080       1090       1100
LAVPSDRSFY GDVKRFSCVW RSLATALENS EDTNDFLEYR YSASLRHTLS 
      1110       1120       1130       1140       1150
HALLHLLSIS QSLDMPALGS SLSGNEGRGI REHLMKYVRA EEGGGEGGGG 
      1160       1170       1180       1190       1200
TEGGEGAQGE KDTGDSFTPQ QRIGGLQQTL IRLKGLEAAG EEERGREEVV 
      1210 
DFLEDLLKTC E
Length:1,211
Mass (Da):132,502
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i06790B9663071575
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSLBET00000021067; ENSLBEP00000019994; ENSLBEG00000015367

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSLBET00000021067; ENSLBEP00000019994; ENSLBEG00000015367

Phylogenomic databases

GeneTreeiENSGT00390000016675

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR025283, DUF4042
PfamiView protein in Pfam
PF13251, DUF4042, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q3FKF5_9LABR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q3FKF5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: February 10, 2021
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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