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Entry version 8 (12 Aug 2020)
Sequence version 1 (10 Apr 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

LAMA5

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LAMA5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000539 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Basement membraneARBA annotation, Extracellular matrix, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501870899727 – 3689Sequence analysisAdd BLAST3663

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi321 ↔ 330PROSITE-ProRule annotation
Disulfide bondi393 ↔ 402PROSITE-ProRule annotation
Disulfide bondi446 ↔ 455PROSITE-ProRule annotation
Disulfide bondi492 ↔ 504PROSITE-ProRule annotation
Disulfide bondi515 ↔ 524PROSITE-ProRule annotation
Disulfide bondi539 ↔ 551PROSITE-ProRule annotation
Disulfide bondi541 ↔ 558PROSITE-ProRule annotation
Disulfide bondi560 ↔ 569PROSITE-ProRule annotation
Disulfide bondi585 ↔ 597PROSITE-ProRule annotation
Disulfide bondi605 ↔ 614PROSITE-ProRule annotation
Disulfide bondi630 ↔ 642PROSITE-ProRule annotation
Disulfide bondi650 ↔ 659PROSITE-ProRule annotation
Disulfide bondi675 ↔ 687PROSITE-ProRule annotation
Disulfide bondi677 ↔ 694PROSITE-ProRule annotation
Disulfide bondi696 ↔ 705PROSITE-ProRule annotation
Disulfide bondi723 ↔ 740PROSITE-ProRule annotation
Disulfide bondi742 ↔ 751PROSITE-ProRule annotation
Disulfide bondi795 ↔ 804PROSITE-ProRule annotation
Disulfide bondi825 ↔ 837PROSITE-ProRule annotation
Disulfide bondi827 ↔ 844PROSITE-ProRule annotation
Disulfide bondi846 ↔ 855PROSITE-ProRule annotation
Disulfide bondi1434 ↔ 1446PROSITE-ProRule annotation
Disulfide bondi1436 ↔ 1453PROSITE-ProRule annotation
Disulfide bondi1455 ↔ 1464PROSITE-ProRule annotation
Disulfide bondi1496 ↔ 1505PROSITE-ProRule annotation
Disulfide bondi1548 ↔ 1557PROSITE-ProRule annotation
Disulfide bondi1573 ↔ 1585PROSITE-ProRule annotation
Disulfide bondi1575 ↔ 1592PROSITE-ProRule annotation
Disulfide bondi1594 ↔ 1603PROSITE-ProRule annotation
Disulfide bondi1875 ↔ 1884PROSITE-ProRule annotation
Disulfide bondi1932 ↔ 1941PROSITE-ProRule annotation
Disulfide bondi1987 ↔ 1996PROSITE-ProRule annotation
Disulfide bondi1999 ↔ 2013PROSITE-ProRule annotation
Disulfide bondi2035 ↔ 2044PROSITE-ProRule annotation
Disulfide bondi2083 ↔ 2092PROSITE-ProRule annotation
Disulfide bondi2126 ↔ 2135PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A3Q2UJC9, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 296Laminin N-terminalInterPro annotationAdd BLAST260
Domaini297 – 355Laminin EGF-likeInterPro annotationAdd BLAST59
Domaini356 – 416Laminin EGF-likeInterPro annotationAdd BLAST61
Domaini426 – 470Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini492 – 538Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini539 – 584Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini585 – 629Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini630 – 674Laminin EGF-likeInterPro annotationAdd BLAST45
Domaini675 – 720Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini722 – 771Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini772 – 824Laminin EGF-likeInterPro annotationAdd BLAST53
Domaini825 – 858Laminin EGF-likeInterPro annotationAdd BLAST34
Domaini1434 – 1479Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini1480 – 1523Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini1524 – 1572Laminin EGF-likeInterPro annotationAdd BLAST49
Domaini1573 – 1623Laminin EGF-likeInterPro annotationAdd BLAST51
Domaini1644 – 1822Laminin IV type AInterPro annotationAdd BLAST179
Domaini1856 – 1905Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini1906 – 1961Laminin EGF-likeInterPro annotationAdd BLAST56
Domaini1962 – 2015Laminin EGF-likeInterPro annotationAdd BLAST54
Domaini2016 – 2062Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini2063 – 2109Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini2110 – 2157Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2726 – 2921LAM_G_DOMAINInterPro annotationAdd BLAST196
Domaini2935 – 3109LAM_G_DOMAINInterPro annotationAdd BLAST175
Domaini3116 – 3285LAM_G_DOMAINInterPro annotationAdd BLAST170
Domaini3334 – 3503LAM_G_DOMAINInterPro annotationAdd BLAST170
Domaini3510 – 3686LAM_G_DOMAINInterPro annotationAdd BLAST177

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3299 – 3334DisorderedSequence analysisAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2210 – 2244Sequence analysisAdd BLAST35
Coiled coili2300 – 2320Sequence analysisAdd BLAST21
Coiled coili2326 – 2346Sequence analysisAdd BLAST21
Coiled coili2365 – 2385Sequence analysisAdd BLAST21
Coiled coili2393 – 2420Sequence analysisAdd BLAST28
Coiled coili2424 – 2451Sequence analysisAdd BLAST28
Coiled coili2553 – 2573Sequence analysisAdd BLAST21
Coiled coili2575 – 2609Sequence analysisAdd BLAST35
Coiled coili2614 – 2681Sequence analysisAdd BLAST68

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3318 – 3334PolarSequence analysisAdd BLAST17

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156537

KEGG Orthology (KO)

More...
KOi
K06240

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.1490, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027267, AH/BAR_dom_sf
IPR013320, ConA-like_dom_sf
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR038684, Laminin_N_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00052, Laminin_B, 1 hit
PF00053, Laminin_EGF, 19 hits
PF00054, Laminin_G_1, 1 hit
PF02210, Laminin_G_2, 4 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit
PF00055, Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 15 hits
SM00180, EGF_Lam, 22 hits
SM00281, LamB, 1 hit
SM00282, LamG, 5 hits
SM00136, LamNT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103657, SSF103657, 1 hit
SSF49899, SSF49899, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022, EGF_1, 2 hits
PS01248, EGF_LAM_1, 9 hits
PS50027, EGF_LAM_2, 21 hits
PS50025, LAM_G_DOMAIN, 5 hits
PS51115, LAMININ_IVA, 1 hit
PS51117, LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A3Q2UJC9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARAAERGLR LLVLLLGLGA GLPAAARPPA SFPGDVNGHS LHPPYFNLAE
60 70 80 90 100
GTRISASATC GEETAGTSGS RRAVEDLYCK LVGGPLAGGD PNQTIQGQYC
110 120 130 140 150
DICSSANSNK AHPITNAIDG TERWWQSPPL SRGLEFNQVN VTLDLGQLFH
160 170 180 190 200
VAYVLIKFAN SPRPDLWVLE RSTDFGLTYE PWQYFASSKR DCIEKFGLQT
210 220 230 240 250
VDRITKDDHA ICTTEYSRIV PLENGEIVVS LVNGRPGAMN FSYSPLLRNF
260 270 280 290 300
TKATNIRLRF LQTNTLLGHL MGKALRDPTV TRRYYYSIKD ISIGGRCVCH
310 320 330 340 350
GHADVCDAKD PSDPYRLQCD CQHNTCGGSC DRCCPGFNQF PWKPATADSA
360 370 380 390 400
NECQPCNCNG HAYDCYYDPE VDRHKASKSR EDKFEGGGVC IDCQHHTTGV
410 420 430 440 450
NCERCIPGYY RSPDHPIDSP YICYRCNCKS DFTDGTCEDL TGRCYCKPNY
460 470 480 490 500
TGEHCNACAE GYLDFPHCYP VPAFAYNDTG EQVLPAGQII NCDCYAGGTE
510 520 530 540 550
GNACRKDPRV GMCVCKPNFQ GTHCDQCTPG HYGPLCQPCQ CSGPGQYDGT
560 570 580 590 600
CDSETGQCLC RTGFEGQLCD RCAPGYFNYP LCQLCGCSAV GTLPGGCDSS
610 620 630 640 650
GRCFCKAEFA GPRCEQCSSG HHSYPHCYAC SCDSRGAVDN NCSPAGQCRC
660 670 680 690 700
HVNFTGHTCN QCALGFYGYP SCTPCQCSRE GSLHSTCNQE TGQCSCRPKV
710 720 730 740 750
TGLRCDSCVP GAYGFPHCEV GSCNPAGLVT ADPSLAPGSC ACRAYVEGPA
760 770 780 790 800
CDRCKPLYWN LTPDNPYGCT SCKCETKGTI SGIAECQQGN GQCFCKPNTC
810 820 830 840 850
GQFCSACKDG YFSMENTNYF GCQGCRCDVG GSLGPSCEER SGACRCRQNT
860 870 880 890 900
RGPTCTQPVR DHYFPDLHHL KFELEEGTTP AGRAVRFGYN PLEFEGFSWR
910 920 930 940 950
GYAQMSSIQP KVVVTLNVTS PDLFRLVFRY VSRGSAIVEG RVSVVEEGKF
960 970 980 990 1000
NICGNCTEQS KQIVFAPSTE PAFVTVPQNS FGEPFVLNPN TWSLIVEAEG
1010 1020 1030 1040 1050
VLLDYLVLLP SSYYEAPILQ LKVTDPCTYQ PAPEQATQNC LLYKYLSVDG
1060 1070 1080 1090 1100
FPAVAGVGAV CRLDNRLPRG CPTEQLTPAH PRMAMCSGND VEVQLSLPIA
1110 1120 1130 1140 1150
QPGKYVLVVE YANPNALHPV AVAISSPHLA MQQGTFTFYP CVYSFLCRGV
1160 1170 1180 1190 1200
AVDSQSRLAT FELTSEATIR FIADLADFFL HKVYLVPAEQ FTMEFVEPKV
1210 1220 1230 1240 1250
HCISVHGMFS SNSSSCIPSR FLKHSQSVVL EGGQALPLAA EVPLAQAVHV
1260 1270 1280 1290 1300
APAGVPLEPA PRPPTAMDST TELILLQPPQ AAVVFNSRIQ NLGRYAFVLH
1310 1320 1330 1340 1350
YYQPNHPTFP VEVLINGGRI WQGQTNATFC PHGYGCRSLV VAEDQIVLDV
1360 1370 1380 1390 1400
TDNDLMVVVR VPEGKQLWLD YILVVPEDSY SSQYLQEEPL DKSYDFISSC
1410 1420 1430 1440 1450
GINSFYINPS TSSRFCRDSA ISLSLFYNNG AQPCQCHEAG ARGSQCEPFG
1460 1470 1480 1490 1500
GQCPCKSNVI GRECSRCATG YWGFPNCRPC DCGTRLCDEV TGQCICPPHT
1510 1520 1530 1540 1550
LKPECVVCEP QTFGCHPLIG CEDCNCSQPG VQELTELGCD VDSGQCKCKP
1560 1570 1580 1590 1600
NVIGRRCDLC APGYYHYPSC RRCDCHPDGT EVSVCDPVTG QCHCKENVEG
1610 1620 1630 1640 1650
PRCDQCRLGT FSLDASNPKG CTKCFCFGAT NRCRSAVKYR AEFIDMNGWL
1660 1670 1680 1690 1700
LMSSDRQEVP TALSLREQLL RADLRNLLDA YQELYWVAPS SYLGDRVSSY
1710 1720 1730 1740 1750
GGHLRYELHS DPRRGDVFIP MESRPDVILK GNQMSIMFLE SSYPSPGEIH
1760 1770 1780 1790 1800
EGQLQLVESN FRHTETHNPV SREELMMVLA NLEQLQIRAL FSQLSSSVSL
1810 1820 1830 1840 1850
RRVVLEIATD TATGVPASNV ELCFCPANYL GDSCQECAPG YYRDTKGLFL
1860 1870 1880 1890 1900
GKCIPCHCNG HSDQCLPGSG ICLNCQHNTE GDHCEQCKDG YVGSRNADGS
1910 1920 1930 1940 1950
LQCVGCPCPL SVASNNFAIG CVHKGSSTQC LCKPGYAGPN CERCAPGYYG
1960 1970 1980 1990 2000
NPLVIGSSCQ PCDCSGNTDP NMLFSSCDSL TGTCMGCMHH TAGVRCEVCA
2010 2020 2030 2040 2050
PGFYGDAVAA KNCTQCNCSP CGTDSCHPQT GQCFCKAGVT GQHCDHCEEG
2060 2070 2080 2090 2100
YYGFEGCSGC RRCDCDVGAM GSSCHAQTGQ CHCLPGVSGS RCQQCAPGYW
2110 2120 2130 2140 2150
GFSERGCRKC ECRGGSCDPR TGECTCSNGL TGKQCDVCMH NYEIPVANGP
2160 2170 2180 2190 2200
DSMRCEVCDS CVLLLLEDLQ SIEMSFPSIR SQLLNLSASS IAWARLHSLN
2210 2220 2230 2240 2250
STMATVANQL REYHRAMNKV RQRADELEDE NIDLTQDLNA LQHRMMMAHS
2260 2270 2280 2290 2300
KANHLEQHTR ETYQRGEQLL LIIQSIQKSI GDLVRQMATF GAANTSTTST
2310 2320 2330 2340 2350
EEFRQKMAEV ERMLREMKQR SLGGQEELAR REHKEAQKLL HRVKNELHAH
2360 2370 2380 2390 2400
WESNQALVSS IQDWLTQHSS QLMDLRDALN EAVNKTRQTE DLNSLNRNNL
2410 2420 2430 2440 2450
EESQQKSREL QKQYGLVQET LRMAESALAK VSNFLQKMES AKEAYEKLAA
2460 2470 2480 2490 2500
LLDGAKLPLT ERVKKFSPAS SKIPIVEQAE EHARLLDELA RNLSSIIQGT
2510 2520 2530 2540 2550
NQDGFIQRAI DASNVYASII EAVRKAERAA HDAHEAAGEA LMNVMSENLG
2560 2570 2580 2590 2600
AISKELKRNS SNLEEAVRRE QTKLNGAIKG TLQTAKNKLA DLRRKKEQLL
2610 2620 2630 2640 2650
SQLQSVQDML GRDQEDTKET IQNAKAAATE ANQTAARVEE TLSTMKKNLD
2660 2670 2680 2690 2700
EWKDKYGGLR NEDLNQAVQD ARKSVSSLES TIPLLLGKLS SLENRRNKNA
2710 2720 2730 2740 2750
TVSENIVRIR QLITQARNAA SKVKVPMKFN GSSGVQVRMP SNLQDLAAYT
2760 2770 2780 2790 2800
SLKFYIQNPE PRSQQDGAEE GRFVLYLGSR EATGDYLGIV LKDRKVQWVY
2810 2820 2830 2840 2850
KLGNEEPASL TVDEEIGEQF AAININRILQ YGQMSVIVER QTVHETKGDS
2860 2870 2880 2890 2900
VAKGEQGLLN LDPHNVVFYV GGYPPSFMPP PTLRYPNYRG CLELDTLNEE
2910 2920 2930 2940 2950
VVSLYNFQHT FQLDTTAEKP CARSKSTGDP WLTDGSYFDG TGYAEIKFES
2960 2970 2980 2990 3000
QFGTTKRFEQ EIRIISYNGI LFFLENQGQF LCLAIRNGKL VLYYDFNTGL
3010 3020 3030 3040 3050
EMAKPSSNAS SISSATNKAI QIFLLKMNNK KRILVRLERL TIFVVEQENS
3060 3070 3080 3090 3100
LENAVSYYLG GVPPAVLPPS LKALFPTGGP IRGCMKGLKA LGKYVDLKRM
3110 3120 3130 3140 3150
NTVGVSYGCT SDLLVARSIS VHGYGYLTLA LKDVPGLRDF YSGFSFQTSQ
3160 3170 3180 3190 3200
REGLLYHHST QEGMCQVSLQ RGQLALNLLE TKVTTENTYA DDRTHYVAFY
3210 3220 3230 3240 3250
SDAQGVRLYV DDELQDTAVG ARASRRQRRQ QDGRALFQLG GSPEPGALSN
3260 3270 3280 3290 3300
LTGCIGNVFV KRRSEPQMVV DLQQNVESIN VTMSCPWGER PQQLRVALKK
3310 3320 3330 3340 3350
DRRKPKVPSR PSSKDRRHNQ AGLCQPQPRT TRGSFRFGGS PSSRWEFEEI
3360 3370 3380 3390 3400
PASFSQRSHF SLEVRLNSSN GLLFYVAGER GTSMALFVSN GRFIFLVDIG
3410 3420 3430 3440 3450
GRRLRIRSKE KYHDRRWHTV FFSRDQSRAQ LVIDGLRAQS AAVATAELFV
3460 3470 3480 3490 3500
AQTPLYVGGV PDGRAKAHML GTSVSSFDGC LRNPQLDGKP LGTPSHTFGV
3510 3520 3530 3540 3550
TPCYEGALES GVFFAADGGS ITLADALATE QDLEVTLEVR PHSASGLIFH
3560 3570 3580 3590 3600
IGTRRSHHSL VLYMEETKVT MRANTGADEF STSVTCPSLC DGQWHTITAT
3610 3620 3630 3640 3650
KRKNIIQVEV DTERNYAVGP SWPPAPSARA MFYLGGLQEA DEASPVSALP
3660 3670 3680
PLPHYVGCIR NLLVNGSHVN LLQTRTVRGS VGLKGCPVL
Length:3,689
Mass (Da):405,554
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3E21749589C0D8B9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2UHC6A0A3Q2UHC6_CHICK
Uncharacterized protein
LAMA5
3,725Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F1NZZ2F1NZZ2_CHICK
Uncharacterized protein
LAMA5
3,686Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AADN05000479 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
XP_015152145.1, XM_015296659.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSGALT00000097748; ENSGALP00000074260; ENSGALG00000005321

Database of genes from NCBI RefSeq genomes

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GeneIDi
428148

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
gga:428148

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN05000479 Genomic DNA No translation available.
RefSeqiXP_015152145.1, XM_015296659.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSGALT00000097748; ENSGALP00000074260; ENSGALG00000005321
GeneIDi428148
KEGGigga:428148

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
3911

Phylogenomic databases

GeneTreeiENSGT00940000156537
KOiK06240

Gene expression databases

ExpressionAtlasiA0A3Q2UJC9, baseline and differential

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR027267, AH/BAR_dom_sf
IPR013320, ConA-like_dom_sf
IPR013032, EGF-like_CS
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
IPR008211, Laminin_N
IPR038684, Laminin_N_sf
PfamiView protein in Pfam
PF00052, Laminin_B, 1 hit
PF00053, Laminin_EGF, 19 hits
PF00054, Laminin_G_1, 1 hit
PF02210, Laminin_G_2, 4 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit
PF00055, Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 15 hits
SM00180, EGF_Lam, 22 hits
SM00281, LamB, 1 hit
SM00282, LamG, 5 hits
SM00136, LamNT, 1 hit
SUPFAMiSSF103657, SSF103657, 1 hit
SSF49899, SSF49899, 5 hits
PROSITEiView protein in PROSITE
PS00022, EGF_1, 2 hits
PS01248, EGF_LAM_1, 9 hits
PS50027, EGF_LAM_2, 21 hits
PS50025, LAM_G_DOMAIN, 5 hits
PS51115, LAMININ_IVA, 1 hit
PS51117, LAMININ_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q2UJC9_CHICK
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q2UJC9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: August 12, 2020
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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