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Entry version 9 (07 Oct 2020)
Sequence version 1 (10 Apr 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

ANK2

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANK2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A3Q2H3M0, baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini47 – 822ANK_REP_REGIONInterPro annotationAdd BLAST776
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati80 – 112ANKPROSITE-ProRule annotationAdd BLAST33
Repeati113 – 145ANKPROSITE-ProRule annotationAdd BLAST33
Repeati146 – 178ANKPROSITE-ProRule annotationAdd BLAST33
Repeati241 – 273ANKPROSITE-ProRule annotationAdd BLAST33
Repeati274 – 306ANKPROSITE-ProRule annotationAdd BLAST33
Repeati307 – 339ANKPROSITE-ProRule annotationAdd BLAST33
Repeati340 – 372ANKPROSITE-ProRule annotationAdd BLAST33
Repeati373 – 405ANKPROSITE-ProRule annotationAdd BLAST33
Repeati406 – 438ANKPROSITE-ProRule annotationAdd BLAST33
Repeati439 – 471ANKPROSITE-ProRule annotationAdd BLAST33
Repeati472 – 504ANKPROSITE-ProRule annotationAdd BLAST33
Repeati505 – 537ANKPROSITE-ProRule annotationAdd BLAST33
Repeati538 – 570ANKPROSITE-ProRule annotationAdd BLAST33
Repeati571 – 603ANKPROSITE-ProRule annotationAdd BLAST33
Repeati604 – 636ANKPROSITE-ProRule annotationAdd BLAST33
Repeati637 – 669ANKPROSITE-ProRule annotationAdd BLAST33
Repeati670 – 702ANKPROSITE-ProRule annotationAdd BLAST33
Repeati703 – 735ANKPROSITE-ProRule annotationAdd BLAST33
Repeati736 – 768ANKPROSITE-ProRule annotationAdd BLAST33
Repeati769 – 801ANKPROSITE-ProRule annotationAdd BLAST33
Domaini1007 – 1162ZU5InterPro annotationAdd BLAST156
Domaini1164 – 1310ZU5InterPro annotationAdd BLAST147
Domaini3576 – 3660DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1463 – 1492DisorderedSequence analysisAdd BLAST30
Regioni1655 – 1762DisorderedSequence analysisAdd BLAST108
Regioni1781 – 2152DisorderedSequence analysisAdd BLAST372
Regioni2199 – 2486DisorderedSequence analysisAdd BLAST288
Regioni2519 – 2804DisorderedSequence analysisAdd BLAST286
Regioni2818 – 2964DisorderedSequence analysisAdd BLAST147
Regioni2981 – 3027DisorderedSequence analysisAdd BLAST47
Regioni3075 – 3113DisorderedSequence analysisAdd BLAST39
Regioni3142 – 3471DisorderedSequence analysisAdd BLAST330
Regioni3556 – 3575DisorderedSequence analysisAdd BLAST20
Regioni3701 – 3720DisorderedSequence analysisAdd BLAST20
Regioni3733 – 3863DisorderedSequence analysisAdd BLAST131

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3485 – 3505Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1655 – 1679PolarSequence analysisAdd BLAST25
Compositional biasi1716 – 1743PolyampholyteSequence analysisAdd BLAST28
Compositional biasi1781 – 1809PolyampholyteSequence analysisAdd BLAST29
Compositional biasi1831 – 1910PolarSequence analysisAdd BLAST80
Compositional biasi1976 – 1990PolarSequence analysisAdd BLAST15
Compositional biasi2013 – 2046PolyampholyteSequence analysisAdd BLAST34
Compositional biasi2047 – 2062PolarSequence analysisAdd BLAST16
Compositional biasi2077 – 2132PolyampholyteSequence analysisAdd BLAST56
Compositional biasi2259 – 2293PolyampholyteSequence analysisAdd BLAST35
Compositional biasi2359 – 2388PolarSequence analysisAdd BLAST30
Compositional biasi2395 – 2409PolarSequence analysisAdd BLAST15
Compositional biasi2529 – 2563PolarSequence analysisAdd BLAST35
Compositional biasi2574 – 2632PolyampholyteSequence analysisAdd BLAST59
Compositional biasi2640 – 2655PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2663 – 2679PolarSequence analysisAdd BLAST17
Compositional biasi2703 – 2730PolarSequence analysisAdd BLAST28
Compositional biasi2731 – 2752PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2766 – 2783PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2821 – 2836PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2844 – 2860PolarSequence analysisAdd BLAST17
Compositional biasi2878 – 2913PolarSequence analysisAdd BLAST36
Compositional biasi2925 – 2964PolarSequence analysisAdd BLAST40
Compositional biasi2981 – 2995PolarSequence analysisAdd BLAST15
Compositional biasi3004 – 3027PolarSequence analysisAdd BLAST24
Compositional biasi3078 – 3109PolarSequence analysisAdd BLAST32
Compositional biasi3162 – 3176PolarSequence analysisAdd BLAST15
Compositional biasi3185 – 3199AcidicSequence analysisAdd BLAST15
Compositional biasi3201 – 3255PolarSequence analysisAdd BLAST55
Compositional biasi3271 – 3286PolyampholyteSequence analysisAdd BLAST16
Compositional biasi3300 – 3327PolarSequence analysisAdd BLAST28
Compositional biasi3367 – 3385PolarSequence analysisAdd BLAST19
Compositional biasi3387 – 3424PolyampholyteSequence analysisAdd BLAST38
Compositional biasi3449 – 3463PolarSequence analysisAdd BLAST15
Compositional biasi3733 – 3752PolarSequence analysisAdd BLAST20
Compositional biasi3777 – 3808PolarSequence analysisAdd BLAST32

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155279

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
IPR000906, ZU5_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 7 hits
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
PF00791, ZU5, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415, ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 23 hits
SM00005, DEATH, 1 hit
SM00218, ZU5, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986, SSF47986, 1 hit
SSF48403, SSF48403, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 20 hits
PS50017, DEATH_DOMAIN, 1 hit
PS51145, ZU5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A3Q2H3M0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNAALCPSC HASKSVGAQG HMPELDKTPD YYGCDSEDTK ELGSRSDSNA
60 70 80 90 100
SFLRAARAGN LDKVVEYLKG GIDINTCNQN GLNALHLAAK EGHVGLVQEL
110 120 130 140 150
LGRGSSVDSA TKKGNTALHI ASLAGQAEVV KVLVKEGANI NAQSQNGFTP
160 170 180 190 200
LYMAAQENHI DVVKYLLENG ANQSTATEDG FTPLAVALQQ GHNQAVAILL
210 220 230 240 250
ENDTKGKVRL PALHIAARKD DTKSAALLLQ NDHNADVQSK SGFTPLHIAA
260 270 280 290 300
HYGNVNVATL LLNRGAAVDF TARNGITPLH VASKRGNTNM VKLLLDRGGQ
310 320 330 340 350
IDAKTRDGLT PLHCAARSGH DQVVELLLER GAPLLARTKN GLSPLHMAAQ
360 370 380 390 400
GDHVECVKHL LQHKAPVDDV TLDYLTALHV AAHCGHYRVT KLLLDKRANP
410 420 430 440 450
NARALNGFTP LHIACKKNRI KVMELLVKYG ASIQAITESG LTPIHVAAFM
460 470 480 490 500
GHLNIVLLLL QNGASPDVTN IRGETALHMA ARAGQVEVVR CLLRNGALVD
510 520 530 540 550
ARAREEQTPL HIASRLGKTE IVQLLLQHMA HPDAATTNGY TPLHISAREG
560 570 580 590 600
QVDVASVLLE AGAAHSLATK KGFTPLHVAA KYGSLDVAKL LLQRRAAADS
610 620 630 640 650
AGKNGLTPLH VAAHYDNQKV ALLLLEKGAS PHATAKNGYT PLHIAAKKNQ
660 670 680 690 700
MQIASTLLNY GAETNIVTKQ GVTPLHLASQ EGHTDMVTLL LDKGANIHMS
710 720 730 740 750
TKSGLTSLHL AAQEDKVNVA DILTKNGADQ DAHTKLGYTP LIVACHYGNV
760 770 780 790 800
KMVNFLLKQG ADVNAKTKNG YTPLHQAAQQ GHTHIINVLL QHGAKPNATT
810 820 830 840 850
ANGNTALAIA KRLGYISVVD TLKVVTEEVT TTTTTITEKH KLNVPETMTE
860 870 880 890 900
VLDVSDEEAL KQFGDQFIDG EVLSDSGDDT MTGDGGEYLR PEDLKELGDD
910 920 930 940 950
SLPSSQFLDG MNYLRYSLEG GRSDSLRSFS SDRSHTLSHA SYLRDSAMID
960 970 980 990 1000
DTVVIPSHQV SALAKEAERN SYRLSWGTEN LDNVALSSSP IHSGRTSPCL
1010 1020 1030 1040 1050
DRDNSSFLVS FMVDARGGAM RGCRHNGLRI IIPPRKCTAP TRVTCRLVKR
1060 1070 1080 1090 1100
HRLATMPPMV EGEGLASRLI EVGPSGAQFL GPVIVEIPHF AALRGKEREL
1110 1120 1130 1140 1150
VVLRSENGDS WKEHYCEYTE DELNEILNGM DEVLDSPEDL EKKRICRIVT
1160 1170 1180 1190 1200
RDFPQYFAVV SRIKQDSNLI GPEGGVLSST VVPQVQAVFP EGALTKRIRV
1210 1220 1230 1240 1250
GLQAQPMHSE LVKKILGNKA TFSPIVTLEP RRRKFHKPIT MTIPVPKASS
1260 1270 1280 1290 1300
DVMLNGFGGD APTLRLLCSI TGGTTPAQWE DITGTTPLTF VNECVSFTTN
1310 1320 1330 1340 1350
VSARFWLIDC RQIQESVTFA SQVYREIICV PYMAKFVVFA KSHDPIEARL
1360 1370 1380 1390 1400
RCFCMTDDKV DKTLEQQENF AEVARSRDVE VLEGKPIYVD CFGNLVPLTK
1410 1420 1430 1440 1450
SGQHHIFSFF AFKENRLPLF VKVRDTTQEP CGRLSFMKEP KSTRGLVHQA
1460 1470 1480 1490 1500
ICNLNITLPV YTKESESDQE QEEEIDMTSE KNDETESTET SVLKSHLVNE
1510 1520 1530 1540 1550
VPVLASPDLL SEVSEMKQDL IKMTAILTTD VSERAGSIKV KELVKAAEEE
1560 1570 1580 1590 1600
PGEPFEIVER VKEDLEKVNE ILRSGTCTRD EASAPRARSE RELVEEEWVI
1610 1620 1630 1640 1650
ISDEEIEEAR QKAPLEITEY PCVEVRIDKE TKEEVEKDST GLVNYLTEDL
1660 1670 1680 1690 1700
NSYVSPHGEQ LQPAQEMAGE TSQAPAVGRS SENEGKDAHP DETQIPQKQQ
1710 1720 1730 1740 1750
KPSLGIKKPV RRKLKEKQKQ KEESLQASTE KTELTKGSSE ESLDEDLGLA
1760 1770 1780 1790 1800
PEPVPAVKAT SPLIEETPIG SIKDKVKALQ KRVEDEQKGR SKLPIRVKGK
1810 1820 1830 1840 1850
EDVPKKIVHR THPAVSPSLK AEKHTPASPA SKTERHSSLS SSAKTERHPP
1860 1870 1880 1890 1900
VSPSSKTEKH SPVSPSAKTE RHSPVSSSSK TEKHSPVSPS TKTERHSPVS
1910 1920 1930 1940 1950
SSTKTERHPP VSPSGKTDKR PPISPSGRPE KHSPVSPGRT EKRSPVSPAG
1960 1970 1980 1990 2000
RIERHPPVSA LGKTEKHLPV SPSGKTEKQP PVSPTSKTER IEETMSVREL
2010 2020 2030 2040 2050
MKAFQSGQDP SKHKAGLFEH KSAKQKQPQE KGKVRVEKEK GQMLTQRETQ
2060 2070 2080 2090 2100
RTESQTIKRG QKILVTGASE SKRGVRASSL GFKKEETVGE KEKGVSHKTP
2110 2120 2130 2140 2150
EPVRSAPEEE SHKENEVPKE KPAEEQGDMD LQISPDRKAS TDFSDVIKQE
2160 2170 2180 2190 2200
LEDNEKYQQF RLSEEPEKAQ LHLDQVLTSP FNTTFPLDYV KDEFLPALSL
2210 2220 2230 2240 2250
PSGALDGSSE SPKHEGVAGS PCGSLMEGTP QISSEESYKH EGLAETPETS
2260 2270 2280 2290 2300
PESLSFSPKK SEEPVREENE TTKLETPREI HLEKEHPSTK DVPDGSEEPG
2310 2320 2330 2340 2350
AAVTEGTEPS AECLLKEATL DPSKDTSSKQ EGDYLDSNSV SLAKETPKGL
2360 2370 2380 2390 2400
AEEASCDEGQ PTYVSSALKA QTDTEAQGST TTKPSDETKA SPLPDVSVKT
2410 2420 2430 2440 2450
GTGTEPKPQG VVRSPQGLEL ALPSRDSEVF SPGADESFAV SHKDSLEASP
2460 2470 2480 2490 2500
VLEDNSSHKT PDSLEPSPLK ESPCRDSLES SPVEPKMKAG ILSSHFPLPA
2510 2520 2530 2540 2550
AVAKTELFTE VASMRSRLLR DPDGSAEDDS LEQTSLMESS GKSPLSPDTP
2560 2570 2580 2590 2600
SSEEISYEVT PKATDASTPK PAVIHECAEE DDLENGEKKR FTPEEEMFKM
2610 2620 2630 2640 2650
VTKIKTFDEL EQEAKQKRDY RKEPKQEESS SSSEPDADSS ADVDEPKHME
2660 2670 2680 2690 2700
SAEEESEVPV AVTSESRKAS SSSESEPELT QLKKGADSGL LPEPVIRVQP
2710 2720 2730 2740 2750
PSPLPSSIDS NSSPEEVQFQ PIVSKQYTFK MNEDTQEESG KSEEEKVCES
2760 2770 2780 2790 2800
HLPEDSQTVS TEGPDMSYDD LKRDDDQPKI YDDHGCEAGS PSSPATPISS
2810 2820 2830 2840 2850
GLHSSCAHDI SEQLVIHKEA LPLQDAEEKD TEGELDVSGL ESPQVEGPSE
2860 2870 2880 2890 2900
SSSSPSSLPR CLASERKELD EDLVSPSSPT KVEATKTDQA FESLPKDCST
2910 2920 2930 2940 2950
EDSSITPQTD RLSVDVPVSD PAETDEISDP QTISPYENVP SQSFFSSEES
2960 2970 2980 2990 3000
KTQTDASHTS FHSSEVCSVT VTSSVAEVAV ESSSSRTVSS KESNFEDQNM
3010 3020 3030 3040 3050
ELESKQESTL WEMQSDGAPS SVESTIPNTS AVVGEKISKV IITKTDVDSD
3060 3070 3080 3090 3100
SWSEIREDDE AFEARVKEEE QKIFGLMVDR QSQGTTPDTT PARTPTEEGT
3110 3120 3130 3140 3150
PTSEQNPFLF QEGKLFEMTR SGAIDMTKRS YADESFHFFQ IGQESSEETL
3160 3170 3180 3190 3200
SEDMKGVSTG AEPPQLETSA ESLALSQSKE PVDDEADLLP DDLSEEVEEI
3210 3220 3230 3240 3250
PSSDAQLNSQ MEISASAETS TEDATSAEPE DLPTTQVSDT PPKSSVKQTS
3260 3270 3280 3290 3300
CPDSPEPAVQ VHLDFSTVTR SVYSDREDDS PDSSPEEQKS VIEIPTAPME
3310 3320 3330 3340 3350
SVPSTESKSK IPIRTIPTST PAPPSAEDEN SLSEDVPPSL DEESKEDETK
3360 3370 3380 3390 3400
PKSKIPVKAP VQRVEQQLLV LDSSLQKTVA PQGQDVTSRA RDDRSKSESD
3410 3420 3430 3440 3450
ADPLDSKAKS PVKTRSYTET ETESGEKAEE LELESEEGAT RTKIFASRLP
3460 3470 3480 3490 3500
VKSKSTTSSC REDTSPTKDS KEHFLDLYRN SIEFFEEISD EASKLVDRLT
3510 3520 3530 3540 3550
QSEREQELVS DDESSSALEV SVIENLPPVE TEHSIPEDIF DTRPIWDESI
3560 3570 3580 3590 3600
ETLIERIPDE NGHDHAEDQQ DEQERTEERL AYIADHLGFS WTELARELDF
3610 3620 3630 3640 3650
TEEQIHQIRI ENPNSLQDQS HALLKYWLER DGKHATDTSL IECLTKINRM
3660 3670 3680 3690 3700
DIVHLLETST EPLQEHMSHS YAEIEQTITL DHSEGFSVLQ EELCLAQQKQ
3710 3720 3730 3740 3750
KEEEQAASKE GEPCDQPPIV SEEDISVGYS TFQDYIPKTD GDSSTTELLP
3760 3770 3780 3790 3800
QTHKEEVQQD FSGKMQDLPE KSPPDHQQEY FVTTPGTEVS ETQKATAASG
3810 3820 3830 3840 3850
SPSKTPEEIT TPPEEERPYL QTPTPSEQGD SPIVQEPEEP LAQREESPRK
3860 3870 3880 3890 3900
TSLVIVESAD DQPQAFERLE EDAAFQKELT EELGELEASS DDEATVTTRV
3910 3920 3930 3940 3950
VRRRVIIQGD DMPDIPPESV TEEEYIDEHG HTVVKKVTRK IIKRYVSSDG
3960 3970 3980 3990 4000
TEKEEITVQG LPQDPVDVEE GDGYSKVIKR VVLKSDTALS EVTLSEPSIL
4010 4020 4030 4040 4050
SSSSQFEAEP VEGRRVSKVV KTTMVHGERM EKHLGDSSLA TDLPSAKDDF
4060 4070 4080 4090 4100
EEALSYTGSH MKVHSPSLVE REILKEDGSV IKRTVMSKAS TRSRAVVKDQ
4110 4120 4130 4140
HGKHIHLEHL EDVPEALDQG DLQRDLQQLL QHFCKEHLKQ EAK
Length:4,143
Mass (Da):454,138
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE653EBDFB03059B1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6SQK7F6SQK7_HORSE
Uncharacterized protein
ANK2
3,958Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6SQP2F6SQP2_HORSE
Uncharacterized protein
ANK2
4,137Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GU11A0A3Q2GU11_HORSE
Uncharacterized protein
ANK2
4,077Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GZG4A0A3Q2GZG4_HORSE
Uncharacterized protein
ANK2
4,164Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HCE8A0A3Q2HCE8_HORSE
Uncharacterized protein
ANK2
4,156Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HHV3A0A3Q2HHV3_HORSE
Uncharacterized protein
ANK2
4,141Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HPB7A0A3Q2HPB7_HORSE
Uncharacterized protein
ANK2
4,069Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I396A0A3Q2I396_HORSE
Uncharacterized protein
ANK2
4,098Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000047901; ENSECAP00000027616; ENSECAG00000024436

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000047901; ENSECAP00000027616; ENSECAG00000024436

Phylogenomic databases

GeneTreeiENSGT00940000155279

Gene expression databases

ExpressionAtlasiA0A3Q2H3M0, baseline

Family and domain databases

Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
IPR000906, ZU5_dom
PfamiView protein in Pfam
PF00023, Ank, 1 hit
PF12796, Ank_2, 7 hits
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
PF00791, ZU5, 1 hit
PRINTSiPR01415, ANKYRIN
SMARTiView protein in SMART
SM00248, ANK, 23 hits
SM00005, DEATH, 1 hit
SM00218, ZU5, 1 hit
SUPFAMiSSF47986, SSF47986, 1 hit
SSF48403, SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 20 hits
PS50017, DEATH_DOMAIN, 1 hit
PS51145, ZU5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q2H3M0_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q2H3M0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: October 7, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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