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UniProtKB - A0A3Q2GU11 (A0A3Q2GU11_HORSE)

Entry version 9 (07 Oct 2020)
Sequence version 1 (10 Apr 2019)
Previous versions | rss
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Protein
Submitted name:

Uncharacterized protein

Gene

ANK2

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANK2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A0A3Q2GU11, baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini47 – 756ANK_REP_REGIONInterPro annotationAdd BLAST710
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati80 – 112ANKPROSITE-ProRule annotationAdd BLAST33
Repeati113 – 145ANKPROSITE-ProRule annotationAdd BLAST33
Repeati146 – 178ANKPROSITE-ProRule annotationAdd BLAST33
Repeati241 – 273ANKPROSITE-ProRule annotationAdd BLAST33
Repeati274 – 306ANKPROSITE-ProRule annotationAdd BLAST33
Repeati307 – 339ANKPROSITE-ProRule annotationAdd BLAST33
Repeati340 – 372ANKPROSITE-ProRule annotationAdd BLAST33
Repeati373 – 405ANKPROSITE-ProRule annotationAdd BLAST33
Repeati406 – 438ANKPROSITE-ProRule annotationAdd BLAST33
Repeati439 – 471ANKPROSITE-ProRule annotationAdd BLAST33
Repeati472 – 504ANKPROSITE-ProRule annotationAdd BLAST33
Repeati505 – 537ANKPROSITE-ProRule annotationAdd BLAST33
Repeati538 – 570ANKPROSITE-ProRule annotationAdd BLAST33
Repeati571 – 603ANKPROSITE-ProRule annotationAdd BLAST33
Repeati604 – 636ANKPROSITE-ProRule annotationAdd BLAST33
Repeati637 – 669ANKPROSITE-ProRule annotationAdd BLAST33
Repeati670 – 702ANKPROSITE-ProRule annotationAdd BLAST33
Repeati703 – 735ANKPROSITE-ProRule annotationAdd BLAST33
Domaini941 – 1096ZU5InterPro annotationAdd BLAST156
Domaini1098 – 1244ZU5InterPro annotationAdd BLAST147
Domaini3510 – 3594DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1397 – 1426DisorderedSequence analysisAdd BLAST30
Regioni1589 – 1696DisorderedSequence analysisAdd BLAST108
Regioni1715 – 2080DisorderedSequence analysisAdd BLAST366
Regioni2133 – 2420DisorderedSequence analysisAdd BLAST288
Regioni2453 – 2738DisorderedSequence analysisAdd BLAST286
Regioni2752 – 2898DisorderedSequence analysisAdd BLAST147
Regioni2916 – 2961DisorderedSequence analysisAdd BLAST46
Regioni3009 – 3047DisorderedSequence analysisAdd BLAST39
Regioni3076 – 3405DisorderedSequence analysisAdd BLAST330
Regioni3490 – 3509DisorderedSequence analysisAdd BLAST20
Regioni3635 – 3654DisorderedSequence analysisAdd BLAST20
Regioni3667 – 3797DisorderedSequence analysisAdd BLAST131

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3419 – 3439Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1589 – 1613PolarSequence analysisAdd BLAST25
Compositional biasi1650 – 1677PolyampholyteSequence analysisAdd BLAST28
Compositional biasi1715 – 1743PolyampholyteSequence analysisAdd BLAST29
Compositional biasi1765 – 1844PolarSequence analysisAdd BLAST80
Compositional biasi1910 – 1924PolarSequence analysisAdd BLAST15
Compositional biasi1947 – 1980PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1981 – 1996PolarSequence analysisAdd BLAST16
Compositional biasi2011 – 2066PolyampholyteSequence analysisAdd BLAST56
Compositional biasi2193 – 2227PolyampholyteSequence analysisAdd BLAST35
Compositional biasi2293 – 2322PolarSequence analysisAdd BLAST30
Compositional biasi2329 – 2343PolarSequence analysisAdd BLAST15
Compositional biasi2463 – 2497PolarSequence analysisAdd BLAST35
Compositional biasi2508 – 2566PolyampholyteSequence analysisAdd BLAST59
Compositional biasi2574 – 2589PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2597 – 2613PolarSequence analysisAdd BLAST17
Compositional biasi2637 – 2664PolarSequence analysisAdd BLAST28
Compositional biasi2665 – 2686PolyampholyteSequence analysisAdd BLAST22
Compositional biasi2700 – 2717PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2755 – 2770PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2778 – 2794PolarSequence analysisAdd BLAST17
Compositional biasi2812 – 2847PolarSequence analysisAdd BLAST36
Compositional biasi2859 – 2898PolarSequence analysisAdd BLAST40
Compositional biasi2938 – 2961PolarSequence analysisAdd BLAST24
Compositional biasi3012 – 3043PolarSequence analysisAdd BLAST32
Compositional biasi3096 – 3110PolarSequence analysisAdd BLAST15
Compositional biasi3119 – 3133AcidicSequence analysisAdd BLAST15
Compositional biasi3135 – 3189PolarSequence analysisAdd BLAST55
Compositional biasi3205 – 3220PolyampholyteSequence analysisAdd BLAST16
Compositional biasi3234 – 3261PolarSequence analysisAdd BLAST28
Compositional biasi3301 – 3319PolarSequence analysisAdd BLAST19
Compositional biasi3321 – 3358PolyampholyteSequence analysisAdd BLAST38
Compositional biasi3383 – 3397PolarSequence analysisAdd BLAST15
Compositional biasi3667 – 3686PolarSequence analysisAdd BLAST20
Compositional biasi3711 – 3742PolarSequence analysisAdd BLAST32

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155279

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.20, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
IPR000906, ZU5_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12796, Ank_2, 7 hits
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
PF00791, ZU5, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01415, ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00248, ANK, 21 hits
SM00005, DEATH, 1 hit
SM00218, ZU5, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47986, SSF47986, 1 hit
SSF48403, SSF48403, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 18 hits
PS50017, DEATH_DOMAIN, 1 hit
PS51145, ZU5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A3Q2GU11-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGNAALCPSC HASKSVGAQG HMPELDKTPD YYGCDSEDTK ELGSRSDSNA 
        60         70         80         90        100
SFLRAARAGN LDKVVEYLKG GIDINTCNQN GLNALHLAAK EGHVGLVQEL 
       110        120        130        140        150
LGRGSSVDSA TKKGNTALHI ASLAGQAEVV KVLVKEGANI NAQSQNGFTP 
       160        170        180        190        200
LYMAAQENHI DVVKYLLENG ANQSTATEDG FTPLAVALQQ GHNQAVAILL 
       210        220        230        240        250
ENDTKGKVRL PALHIAARKD DTKSAALLLQ NDHNADVQSK SGFTPLHIAA 
       260        270        280        290        300
HYGNVNVATL LLNRGAAVDF TARNGITPLH VASKRGNTNM VKLLLDRGGQ 
       310        320        330        340        350
IDAKTRDGLT PLHCAARSGH DQVVELLLER GAPLLARTKN GLSPLHMAAQ 
       360        370        380        390        400
GDHVECVKHL LQHKAPVDDV TLDYLTALHV AAHCGHYRVT KLLLDKRANP 
       410        420        430        440        450
NARALRGETA LHMAARAGQV EVVRCLLRNG ALVDARAREE QTPLHIASRL 
       460        470        480        490        500
GKTEIVQLLL QHMAHPDAAT TNGYTPLHIS AREGQVDVAS VLLEAGAAHS 
       510        520        530        540        550
LATKKGFTPL HVAAKYGSLD VAKLLLQRRA AADSAGKNGL TPLHVAAHYD 
       560        570        580        590        600
NQKVALLLLE KGASPHATAK NGYTPLHIAA KKNQMQIAST LLNYGAETNI 
       610        620        630        640        650
VTKQGVTPLH LASQEGHTDM VTLLLDKGAN IHMSTKSGLT SLHLAAQEDK 
       660        670        680        690        700
VNVADILTKN GADQDAHTKL GYTPLIVACH YGNVKMVNFL LKQGADVNAK 
       710        720        730        740        750
TKNGYTPLHQ AAQQGHTHII NVLLQHGAKP NATTANGNTA LAIAKRLGYI 
       760        770        780        790        800
SVVDTLKVVT EEVTTTTTTI TEKHKLNVPE TMTEVLDVSD EEALKQFGDQ 
       810        820        830        840        850
FIDGEVLSDS GDDTMTGDGG EYLRPEDLKE LGDDSLPSSQ FLDGMNYLRY 
       860        870        880        890        900
SLEGGRSDSL RSFSSDRSHT LSHASYLRDS AMIDDTVVIP SHQVSALAKE 
       910        920        930        940        950
AERNSYRLSW GTENLDNVAL SSSPIHSGRT SPCLDRDNSS FLVSFMVDAR 
       960        970        980        990       1000
GGAMRGCRHN GLRIIIPPRK CTAPTRVTCR LVKRHRLATM PPMVEGEGLA 
      1010       1020       1030       1040       1050
SRLIEVGPSG AQFLGPVIVE IPHFAALRGK ERELVVLRSE NGDSWKEHYC 
      1060       1070       1080       1090       1100
EYTEDELNEI LNGMDEVLDS PEDLEKKRIC RIVTRDFPQY FAVVSRIKQD 
      1110       1120       1130       1140       1150
SNLIGPEGGV LSSTVVPQVQ AVFPEGALTK RIRVGLQAQP MHSELVKKIL 
      1160       1170       1180       1190       1200
GNKATFSPIV TLEPRRRKFH KPITMTIPVP KASSDVMLNG FGGDAPTLRL 
      1210       1220       1230       1240       1250
LCSITGGTTP AQWEDITGTT PLTFVNECVS FTTNVSARFW LIDCRQIQES 
      1260       1270       1280       1290       1300
VTFASQVYRE IICVPYMAKF VVFAKSHDPI EARLRCFCMT DDKVDKTLEQ 
      1310       1320       1330       1340       1350
QENFAEVARS RDVEVLEGKP IYVDCFGNLV PLTKSGQHHI FSFFAFKENR 
      1360       1370       1380       1390       1400
LPLFVKVRDT TQEPCGRLSF MKEPKSTRGL VHQAICNLNI TLPVYTKESE 
      1410       1420       1430       1440       1450
SDQEQEEEID MTSEKNDETE STETSVLKSH LVNEVPVLAS PDLLSEVSEM 
      1460       1470       1480       1490       1500
KQDLIKMTAI LTTDVSERAG SIKVKELVKA AEEEPGEPFE IVERVKEDLE 
      1510       1520       1530       1540       1550
KVNEILRSGT CTRDEASAPR ARSERELVEE EWVIISDEEI EEARQKAPLE 
      1560       1570       1580       1590       1600
ITEYPCVEVR IDKETKEEVE KDSTGLVNYL TEDLNSYVSP HGEQLQPAQE 
      1610       1620       1630       1640       1650
MAGETSQAPA VGRSSENEGK DAHPDETQIP QKQQKPSLGI KKPVRRKLKE 
      1660       1670       1680       1690       1700
KQKQKEESLQ ASTEKTELTK GSSEESLDED LGLAPEPVPA VKATSPLIEE 
      1710       1720       1730       1740       1750
TPIGSIKDKV KALQKRVEDE QKGRSKLPIR VKGKEDVPKK IVHRTHPAVS 
      1760       1770       1780       1790       1800
PSLKAEKHTP ASPASKTERH SSLSSSAKTE RHPPVSPSSK TEKHSPVSPS 
      1810       1820       1830       1840       1850
AKTERHSPVS SSSKTEKHSP VSPSTKTERH SPVSSSTKTE RHPPVSPSGK 
      1860       1870       1880       1890       1900
TDKRPPISPS GRPEKHSPVS PGRTEKRSPV SPAGRIERHP PVSALGKTEK 
      1910       1920       1930       1940       1950
HLPVSPSGKT EKQPPVSPTS KTERIEETMS VRELMKAFQS GQDPSKHKAG 
      1960       1970       1980       1990       2000
LFEHKSAKQK QPQEKGKVRV EKEKGQMLTQ RETQRTESQT IKRGQKILVT 
      2010       2020       2030       2040       2050
GASESKRGVR ASSLGFKKEE TVGEKEKGVS HKTPEPVRSA PEEESHKENE 
      2060       2070       2080       2090       2100
VPKEKPAEEQ GDMDLQISPD RKASTDFSDV IKQELEDNEK YQQFRLSEEP 
      2110       2120       2130       2140       2150
EKAQLHLDQV LTSPFNTTFP LDYVKDEFLP ALSLPSGALD GSSESPKHEG 
      2160       2170       2180       2190       2200
VAGSPCGSLM EGTPQISSEE SYKHEGLAET PETSPESLSF SPKKSEEPVR 
      2210       2220       2230       2240       2250
EENETTKLET PREIHLEKEH PSTKDVPDGS EEPGAAVTEG TEPSAECLLK 
      2260       2270       2280       2290       2300
EATLDPSKDT SSKQEGDYLD SNSVSLAKET PKGLAEEASC DEGQPTYVSS 
      2310       2320       2330       2340       2350
ALKAQTDTEA QGSTTTKPSD ETKASPLPDV SVKTGTGTEP KPQGVVRSPQ 
      2360       2370       2380       2390       2400
GLELALPSRD SEVFSPGADE SFAVSHKDSL EASPVLEDNS SHKTPDSLEP 
      2410       2420       2430       2440       2450
SPLKESPCRD SLESSPVEPK MKAGILSSHF PLPAAVAKTE LFTEVASMRS 
      2460       2470       2480       2490       2500
RLLRDPDGSA EDDSLEQTSL MESSGKSPLS PDTPSSEEIS YEVTPKATDA 
      2510       2520       2530       2540       2550
STPKPAVIHE CAEEDDLENG EKKRFTPEEE MFKMVTKIKT FDELEQEAKQ 
      2560       2570       2580       2590       2600
KRDYRKEPKQ EESSSSSEPD ADSSADVDEP KHMESAEEES EVPVAVTSES 
      2610       2620       2630       2640       2650
RKASSSSESE PELTQLKKGA DSGLLPEPVI RVQPPSPLPS SIDSNSSPEE 
      2660       2670       2680       2690       2700
VQFQPIVSKQ YTFKMNEDTQ EESGKSEEEK VCESHLPEDS QTVSTEGPDM 
      2710       2720       2730       2740       2750
SYDDLKRDDD QPKIYDDHGC EAGSPSSPAT PISSGLHSSC AHDISEQLVI 
      2760       2770       2780       2790       2800
HKEALPLQDA EEKDTEGELD VSGLESPQVE GPSESSSSPS SLPRCLASER 
      2810       2820       2830       2840       2850
KELDEDLVSP SSPTKVEATK TDQAFESLPK DCSTEDSSIT PQTDRLSVDV 
      2860       2870       2880       2890       2900
PVSDPAETDE ISDPQTISPY ENVPSQSFFS SEESKTQTDA SHTSFHSSEV 
      2910       2920       2930       2940       2950
CSVTVTSSVA EVAVESSSSR TVSSKESNFE DQNMELESKQ ESTLWEMQSD 
      2960       2970       2980       2990       3000
GAPSSVESTI PNTSAVVGEK ISKVIITKTD VDSDSWSEIR EDDEAFEARV 
      3010       3020       3030       3040       3050
KEEEQKIFGL MVDRQSQGTT PDTTPARTPT EEGTPTSEQN PFLFQEGKLF 
      3060       3070       3080       3090       3100
EMTRSGAIDM TKRSYADESF HFFQIGQESS EETLSEDMKG VSTGAEPPQL 
      3110       3120       3130       3140       3150
ETSAESLALS QSKEPVDDEA DLLPDDLSEE VEEIPSSDAQ LNSQMEISAS 
      3160       3170       3180       3190       3200
AETSTEDATS AEPEDLPTTQ VSDTPPKSSV KQTSCPDSPE PAVQVHLDFS 
      3210       3220       3230       3240       3250
TVTRSVYSDR EDDSPDSSPE EQKSVIEIPT APMESVPSTE SKSKIPIRTI 
      3260       3270       3280       3290       3300
PTSTPAPPSA EDENSLSEDV PPSLDEESKE DETKPKSKIP VKAPVQRVEQ 
      3310       3320       3330       3340       3350
QLLVLDSSLQ KTVAPQGQDV TSRARDDRSK SESDADPLDS KAKSPVKTRS 
      3360       3370       3380       3390       3400
YTETETESGE KAEELELESE EGATRTKIFA SRLPVKSKST TSSCREDTSP 
      3410       3420       3430       3440       3450
TKDSKEHFLD LYRNSIEFFE EISDEASKLV DRLTQSEREQ ELVSDDESSS 
      3460       3470       3480       3490       3500
ALEVSVIENL PPVETEHSIP EDIFDTRPIW DESIETLIER IPDENGHDHA 
      3510       3520       3530       3540       3550
EDQQDEQERT EERLAYIADH LGFSWTELAR ELDFTEEQIH QIRIENPNSL 
      3560       3570       3580       3590       3600
QDQSHALLKY WLERDGKHAT DTSLIECLTK INRMDIVHLL ETSTEPLQEH 
      3610       3620       3630       3640       3650
MSHSYAEIEQ TITLDHSEGF SVLQEELCLA QQKQKEEEQA ASKEGEPCDQ 
      3660       3670       3680       3690       3700
PPIVSEEDIS VGYSTFQDYI PKTDGDSSTT ELLPQTHKEE VQQDFSGKMQ 
      3710       3720       3730       3740       3750
DLPEKSPPDH QQEYFVTTPG TEVSETQKAT AASGSPSKTP EEITTPPEEE 
      3760       3770       3780       3790       3800
RPYLQTPTPS EQGDSPIVQE PEEPLAQREE SPRKTSLVIV ESADDQPQAF 
      3810       3820       3830       3840       3850
ERLEEDAAFQ KELTEELGEL EASSDDEATV TTRVVRRRVI IQGDDMPDIP 
      3860       3870       3880       3890       3900
PESVTEEEYI DEHGHTVVKK VTRKIIKRYV SSDGTEKEEI TVQGLPQDPV 
      3910       3920       3930       3940       3950
DVEEGDGYSK VIKRVVLKSD TALSEVTLSE PSILSSSSQF EAEPVEGRRV 
      3960       3970       3980       3990       4000
SKVVKTTMVH GERMEKHLGD SSLATDLPSA KDDFEEALSY TGSHMKVHSP 
      4010       4020       4030       4040       4050
SLVEREILKE DGSVIKRTVM SKASTRSRAV VKDQHGKHIH LEHLEDVPEA 
      4060       4070 
LDQGDLQRDL QQLLQHFCKE HLKQEAK
Length:4,077
Mass (Da):447,060
Last modified:April 10, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i94D46A35E8690D1C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6SQK7F6SQK7_HORSE
Uncharacterized protein
ANK2
3,958Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6SQP2F6SQP2_HORSE
Uncharacterized protein
ANK2
4,137Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2GZG4A0A3Q2GZG4_HORSE
Uncharacterized protein
ANK2
4,164Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2H3M0A0A3Q2H3M0_HORSE
Uncharacterized protein
ANK2
4,143Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HCE8A0A3Q2HCE8_HORSE
Uncharacterized protein
ANK2
4,156Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HHV3A0A3Q2HHV3_HORSE
Uncharacterized protein
ANK2
4,141Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HPB7A0A3Q2HPB7_HORSE
Uncharacterized protein
ANK2
4,069Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2I396A0A3Q2I396_HORSE
Uncharacterized protein
ANK2
4,098Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSECAT00000065402; ENSECAP00000024136; ENSECAG00000024436

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSECAT00000065402; ENSECAP00000024136; ENSECAG00000024436

Phylogenomic databases

GeneTreeiENSGT00940000155279

Gene expression databases

ExpressionAtlasiA0A3Q2GU11, baseline

Family and domain databases

Gene3Di1.25.40.20, 2 hits
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR040745, Ankyrin_UPA
IPR011029, DEATH-like_dom_sf
IPR000488, Death_domain
IPR000906, ZU5_dom
PfamiView protein in Pfam
PF12796, Ank_2, 7 hits
PF00531, Death, 1 hit
PF17809, UPA_2, 1 hit
PF00791, ZU5, 1 hit
PRINTSiPR01415, ANKYRIN
SMARTiView protein in SMART
SM00248, ANK, 21 hits
SM00005, DEATH, 1 hit
SM00218, ZU5, 1 hit
SUPFAMiSSF47986, SSF47986, 1 hit
SSF48403, SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 18 hits
PS50017, DEATH_DOMAIN, 1 hit
PS51145, ZU5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q2GU11_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q2GU11
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: April 10, 2019
Last sequence update: April 10, 2019
Last modified: October 7, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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