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Entry version 7 (11 Dec 2019)
Sequence version 1 (13 Feb 2019)
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Protein
Submitted name:

proteasome-associated protein ECM29 homolog

Gene

Kiaa0368

Organism
Mesocricetus auratus (Golden hamster)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
proteasome-associated protein ECM29 homologImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Kiaa0368Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMesocricetus auratus (Golden hamster)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10036 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaCricetidaeCricetinaeMesocricetus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000189706 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

ProteasomeImported

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1149 – 1231Vac14_Fab1_bdInterPro annotationAdd BLAST83

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni193 – 217DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi193 – 213PolarSequence analysisAdd BLAST21

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024372 Ecm29
IPR032878 Vac14_Fab1-bd

The PANTHER Classification System

More...
PANTHERi
PTHR23346:SF19 PTHR23346:SF19, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13001 Ecm29, 1 hit
PF12755 Vac14_Fab1_bd, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3Q0DFP7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAASASQ DELNQLERVF LRLGHAETDE QLQNIISKFL PPVLLKLSST
60 70 80 90 100
QEGVRKKVME LLVHLNKRIK SRPKIQLPVE TLLVQYQDPA AVSFVTNFTI
110 120 130 140 150
IYVKMGYPRL PVEKQCELAP TLLTAMEGKP QPQQDSLMHL LIPTLFHMKY
160 170 180 190 200
PAESSRSAAP FNLAEKPKTV QLLLDFMLDV LLMPYGYVLN ESQSRQNSSS
210 220 230 240 250
TQGSSSNSGG GSGIPQPPPG MSFYAAKRVI GDNPWTPEQL EQCKLGIVKF
260 270 280 290 300
IEAEQVPELE AVLHLVIASS DTRHSVATAA DLELKSKQSL IDWNNPAIIN
310 320 330 340 350
KMYKVYLGDI PLKTKEGAVL KPELKRDPVS TRVKLKIVPH LLRSRQAAET
360 370 380 390 400
FPANIQVVYD GLFGTNTNSK LRTLSLQFVH HICITCPEIK IKPLGPMLLN
410 420 430 440 450
GLTKLINEYK EDPKLLSMAY SAVGKLSSRM PHLFTKDIAL VQQLFEALCK
460 470 480 490 500
EEPETRLAIQ EALSMMVGAY STLEGAQRTL MEALVASYLI KPEVQVRQVA
510 520 530 540 550
VKFASTVFPS DHIPSRYLLL LAAGDPREEV HGEAQRVLRC LPGRNKKESA
560 570 580 590 600
AKQMPSFPEM VYYIQEKASH RMKTPVKYMT GTTVLPFNPA AFGEIILYLR
610 620 630 640 650
MCLAHSAGVV PTSQSLADMQ DHAPAIGRYI RTLMSSSQAT ASSSNKSGET
660 670 680 690 700
NPVQIYIGLL QQLLAGVGGL PVMYCLLEAV SVYPEKLATK FVDKTEWIKS
710 720 730 740 750
LMSSSKEEMR ELAALFYSVV VSTVSGNELK SMIEQLIKAT KDNHSPEVQH
760 770 780 790 800
GSLLALGFTV GRYLAKKRMR MAEQRDLETD ADLLPEQEDL IRSATEIIGS
810 820 830 840 850
FLDSTSPLLA IAACTALGEI GRNGPLPIPS EGSGFTKLHL VESLLNRIPS
860 870 880 890 900
SKETNKMKER AIQTLGYFPV GDGDFPHQKL LLRGLMDSVE AKQIELQFTI
910 920 930 940 950
GEAITSAAIG TNSVAARDAW LVTEEEYTPL AGAKMNDVVP WVLEVILSKH
960 970 980 990 1000
IISPNPHVRQ AACIWLLSLV RKLSTHIEVK SHLKEIQSAF VSVLSENDEL
1010 1020 1030 1040 1050
SQDVASKGLG LVYELGSEQD QQELVSTLVE TLMTGKRAKH EVSGETVVFQ
1060 1070 1080 1090 1100
GGGLGKTPDG QGLSTYKELC SLASDLSQPD LVYKFMNLAN HHAMWNSRKG
1110 1120 1130 1140 1150
AAFGFNVIAT RAGEQLAPFL PQLIPRLYRY QFDPNLGIRQ AMTSIWNALV
1160 1170 1180 1190 1200
TDKSMVDKYL KEILQDVIKN LTSNMWRVRE SSCLALNDLL RGRPLDDVID
1210 1220 1230 1240 1250
KLPEMWETLF RVQDDIKESV RKTAELVLKT LSKVCVKMCD PAKGAAGQRT
1260 1270 1280 1290 1300
IAVLLPCLLD KGMMSPVTEV RALSINTLVK ISKSAGAMLK PHAPKLIPAL
1310 1320 1330 1340 1350
LESLSVLEPQ VLNYLSLRAT EQEKAAMDSA RLSAAKSSPM METINMCLQY
1360 1370 1380 1390 1400
LDVSVLGELV PRLCELIRSG VGLGTKGGCA SVIVSLTTQC PQDLTPYSGK
1410 1420 1430 1440 1450
LMSALLSGLT DRNSVIQKSC AFAMGHLVRT SRDSSTEKLL QKLNGWYMEK
1460 1470 1480 1490 1500
EEPVYKTACA LTIHAIGRYS PDVLKNHAKE VLPLAFLGMH EVADEEKSEK
1510 1520 1530 1540 1550
EECNLWTEVW QENVPGSFGG IRLYLQELIA ITQKALQSQS WKMKAQGAIA
1560 1570 1580 1590 1600
MASIAKQTSS LVPPYLGMIL SALLQGLAGR TWAGKEELLK AIACVVTACS
1610 1620 1630 1640 1650
TELEKSVPNQ PTTNEILQAV LKECCKENLK YKIVAITCAA DVLKATKEDR
1660 1670 1680 1690 1700
FQEFSDIVIP LIKKNSLESM GVRSTKAEEE NDKERELQLE SLLGAFESLG
1710 1720 1730 1740 1750
KAWPRNPETQ RCYRQELCKL MCERLRLSTW KVQLGVLQSM NAFFQGLMLL
1760 1770 1780 1790 1800
EEEHADSEAL AEILLETCKS ITYSLENKTY SSVRTEALSV VELLLKKLEE
1810 1820 1830 1840
AKQWESLTVE CRRLLVESLA TMETDNRPEL QEKASVLKKT LESLE
Length:1,845
Mass (Da):204,215
Last modified:February 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i79573C153622DC91
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_021091588.1, XM_021235929.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_021091588.1, XM_021235929.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di1.25.10.10, 2 hits
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR024372 Ecm29
IPR032878 Vac14_Fab1-bd
PANTHERiPTHR23346:SF19 PTHR23346:SF19, 1 hit
PfamiView protein in Pfam
PF13001 Ecm29, 1 hit
PF12755 Vac14_Fab1_bd, 1 hit
SUPFAMiSSF48371 SSF48371, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3Q0DFP7_MESAU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3Q0DFP7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 13, 2019
Last sequence update: February 13, 2019
Last modified: December 11, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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